Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7187 results
Cited 45 times since 1989 (1.3 per year) source: EuropePMC
Journal of immunology (Baltimore, Md. : 1950), Volume 142, Issue 6, 1 1 1989, Pages 2024-2030 Biosynthesis of complement factor H by human umbilical vein endothelial cells. Regulation by T cell growth factor and IFN-gamma. Brooimans RA, Hiemstra PS, van der Ark AA, Sim RB, van Es LA, Daha MR
The present studies were initiated to characterize a 150-kDa molecule with inhibitory activity for C3bBb formation, which is present in human umbilical vein endothelial cells (HUVEC). Therefore, human endothelial culture supernatants (HECS) were analyzed for the presence of human complement factor H by ELISA. It was found that H was present in HECS. An immunoblot analysis of affinity purified H from HECS showed that the size of HUVEC H was identical to that of plasma H. The mean production of H... Abstract
Cited 33 times since 1989 (1 per year) source: EuropePMC
Experimental hematology, Volume 17, Issue 3, 1 1 1989, Pages 229-234 Interleukin 1 and poly(rI).poly(rC) induce production of granulocyte CSF, macrophage CSF, and granulocyte-macrophage CSF by human endothelial cells. Fibbe WE, Daha MR, Hiemstra PS, Duinkerken N, Lurvink E, Ralph P, Altrock BW, Kaushansky K, Willemze R, Falkenburg JH
Electrophoretically pure human interleukin 1 (IL-1) beta was found to stimulate human endothelial cells in monolayer culture to elaborate colony-stimulating activity (CSA). Supernatant fluids from cultures stimulated with increasing concentrations of IL-1 were found to stimulate colony formation of myeloid (CFU-GM), erythroid (BFU-E), and multipotent (CFU-GEMM) progenitor cells in a dose-dependent fashion. The effect on mixed colony formation, however, was less than on CFU-GM and BFU-E growth. S... Abstract
Cited 1 times since 1989 (0 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 133, Issue 10, 1 1 1989, Pages 494-498 [Diagnosis and treatment of differentiated thyroid carcinoma] Schelfhout LJ, Goslings BM, Hamming JF, Bruining HA, Krenning EP, van de Velde CJ
Chest, Volume 95, Issue 3, 1 1 1989, Pages 709-710 Oral etoposide for a 95-year-old patient with small cell lung cancer. Smit EF, Sleijfer DT, Postmus PE
Cited 4 times since 1989 (0.1 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 25, Issue 2, 1 1 1989, Pages 377-378 High-dose etoposide for meningeal carcinomatosis in patients with small cell lung cancer. Postmus PE, Haaxma-Reiche H, Berendsen HH, Sleijfer DT
Cited 1 times since 1989 (0 per year) source: EuropePMC
Deutsche medizinische Wochenschrift (1946), Volume 114, Issue 6, 1 1 1989, Pages 214-217 [Papaverine-induced priapism. Experiences with a new urologic emergency]. Schneider AW, Busch R, Gonnermann D, Klosterhalfen H
Ten patients with priapism after self-administered intracavernous papaverine injection for erectile impotence had to be treated as emergencies between September 1985 and February 1988. In half the patients it was possible to achieve penile detumescence by puncture of the corpora cavernosa, injection of 2-5 mg metaraminol or both, but failed in the remainder, requiring the intracavernous injection of 10-30 mg metaraminol in 500 ml physiological saline. Surgical treatment was necessary in one case... Abstract
Cited 21 times since 1989 (0.6 per year) source: EuropePMC
British journal of cancer, Volume 59, Issue 2, 1 1 1989, Pages 254-256 High dose etoposide for brain metastases of small cell lung cancer. A phase II study. The EORTC Lung Cancer Cooperative Group. Postmus PE, Haaxma-Reiche H, Sleijfer DT, Kirkpatrick A, McVie JG, Kleisbauer JP
Symptomatic brain metastases are found in about 40% of patients with small cell lung cancer. Cranial irradiation is the first line treatment for this form of metastatic disease. Frequently brain metastases recur after this treatment or develop after prophylactic cranial irradiation. For these patients no effective antitumour therapy is available. In this study the efficacy of high dose etoposide 1.5 g m-2 was evaluated. In 10 (43%) out of 23 evaluable patients a response was seen. Toxicity was s... Abstract
L' Orthodontie francaise, Volume 60 Pt 2, 1 1 1989, Pages 543-557 [Reciprocal transplantation of cranial and facial sutures in guinea pigs: a histologic evaluation] de Coster T
The objectives of this experimental study were to evaluate histological responses following cross-transplantations of the contrastive metopic and internasal sutures and to determine the nature of their integration and metamorphosis in the respective new functional environments. Twenty-two Hartly guinea pigs were utilized. They were divided into three groups: a nonsurgical control group, a surgical control group, and an experimental group. Vital dyes were injected weekly to each animal. Two histo... Abstract
L' Orthodontie francaise, Volume 60 Pt 2, 1 1 1989, Pages 495-520 [Vertical dimension. Discussion of the report] Horn AJ, Decker A, De Coster T, Planas P, Decosse MH, Hadjean E, Philippe J
Cited 9 times since 1989 (0.3 per year) source: EuropePMC
Cancer chemotherapy and pharmacology, Volume 25, Issue 3, 1 1 1989, Pages 202-204 A phase II study of carboplatin and vincristine in previously treated patients with small-cell lung cancer. Smit EF, Berendsen HH, de Vries EG, Mulder NH, Postmus PE
A total of 28 previously treated patients with small-cell lung cancer were treated at relapse with 400 mg/m2 carboplatin and 2 mg vincristine on days 1 and 8, every 4 weeks. Ten partial responses (PRs) (37%) but no complete responses (CRs) were seen. Median survival after the start of second-line treatment was 120 days (range, 39-503 days). Toxicity of this regimen was moderate, including WHO grade 3/4 myelosuppression in 26% of courses (n = 66). Eight PRs were seen in a subgroup of 22 patients... Abstract
Cited 11 times since 1989 (0.3 per year) source: EuropePMC
International journal of cardiac imaging, Volume 4, Issue 2-4, 1 1 1989, Pages 127-133 Laser ablation and the need for intra-arterial imaging. Borst C, Rienks R, Mali WP, van Erven L
In 48 patients with severe claudication due to a total obstruction of the femoropopliteal artery, percutaneous recanalization was attempted with a 2.2 mm diameter rounded sapphire contact probe in conjunction with a continuous wave Nd:YAG laser. In eight patients the contact probe laser catheter took a subintimal course that could not be redressed. Laser recanalization needs high-resolution diagnostic information on the complex anatomy of the obstruction. Intra-arterial ultrasound imaging may pr... Abstract
Cited 1 times since 1989 (0 per year) source: EuropePMC
Monographs in allergy, Volume 26, 1 1 1989, Pages 82-95 Rheumatoid factor and complement activation. Doekes G, Hiemstra PS
Cited 3 times since 1989 (0.1 per year) source: EuropePMC
Progress in clinical and biological research, Volume 297, 1 1 1989, Pages 247-60; discussion 260-1 Interaction of immunoglobulin A with complement and phagocytic cells. Daha MR, Gorter A, Rits M, van Es LA, Hiemstra PS
Cited 4 times since 1989 (0.1 per year) source: EuropePMC
Pediatric cardiology, Volume 10, Issue 1, 1 1 1989, Pages 1-9 Anatomic correction for transposition of the great arteries: first follow-up (38 patients). Klautz RJ, Ottenkamp J, Quaegebeur JM, Buis-Liem TN, Rohmer J
Between April 1983 and October 1985, 38 consecutive patients with transposition of the great arteries (TGA) underwent anatomic correction. Ages ranged from 1 day to 284 weeks (mean 26.2 weeks). Simple TGA was present in 17 patients, 17 had an associated ventricular septal defect, and the remaining four had a Taussig-Bing anomaly. Hospital mortality was 2 of 38, with 1 late death. Follow-up time varied from 6 to 35 months. Postoperative cardiac catheterization was performed in 34 of the 36 early... Abstract
Cited 52 times since 1988 (1.5 per year) source: EuropePMC
Cancer research, Volume 48, Issue 23, 1 1 1988, Pages 6891-6899 Characterization of three small cell lung cancer cell lines established from one patient during longitudinal follow-up. Berendsen HH, de Leij L, de Vries EG, Mesander G, Mulder NH, de Jong B, Buys CH, Postmus PE, Poppema S, Sluiter HJ
Three classic-type, small cell lung cancer cell lines (GLC-14, GLC-16, and GLC-19) have been established from one patient during longitudinal follow-up. During this period the tumor changed from sensitive to completely resistant to (chemo)therapy. A phenotypical and functional characterization of the different cell lines is given in combination with the matching clinical data. (a) The cell lines have been compared with the biopsies from which they were derived. There was a good match between the... Abstract
Cited 3 times since 1988 (0.1 per year) source: EuropePMC
The European respiratory journal, Volume 1, Issue 10, 1 1 1988, Pages 969-971 An unusual cause of subcutaneous emphysema, pneumomediastinum and pneumoperitoneum. Boersma WG, Teengs JP, Postmus PE, Aalders JC, Sluiter HJ
A 62 year old female with subcutaneous emphysema, pneumomediastinum and pneumoperitoneum, was observed. Pneumothorax, however, was not present. Laparotomy revealed a large infiltrate in the left lower abdomen, which had penetrated the anterior abdominal wall. Microscopically, a recurrence of previously diagnosed vulval carcinoma was demonstrated. Despite intensive treatment the patient died two months later. Abstract
Cited 14 times since 1988 (0.4 per year) source: EuropePMC
European journal of immunology, Volume 18, Issue 12, 1 1 1988, Pages 1873-1880 Activation of rat complement by soluble and insoluble rat IgA immune complexes. Rits M, Hiemstra PS, Bazin H, Van Es LA, Vaerman JP, Daha MR
The ability of rat monoclonal IgA, specific for 2,4-dinitrophenyl (DNA), to activate the complement (C) system of the rat was investigated using aggregated IgA or IgA immune complexes (IC). IgA was coated onto a solid phase, and tested for its capacity to bind C3 upon incubation at 37 degrees C in normal rat serum (NRS) in the presence of Mg-EGTA. Binding of C3 was observed dependent on the dose of dimeric (d-), polymeric (p-) and secretory IgA tested. In contrast, little C3 fixation was observe... Abstract
Cited 2 times since 1988 (0.1 per year) source: EuropePMC
Journal of neuro-oncology, Volume 6, Issue 3, 1 1 1988, Pages 231-232 Podophyllotoxins for brain metastases of small cell lung cancer. Haaxma-Reiche H, Berendsen HH, Postmus PE
A patient with brain metastases of small cell lung cancer (SCLC) responded initially to cranial irradiation. Recurrences were subsequently successfully treated with high-dose intravenous etoposide (VP 16-213) and teniposide (VM 26). Epipodophyllotoxins are potentially useful for CNS metastases of SCLC. Abstract
Cited 5 times since 1988 (0.1 per year) source: EuropePMC
Arzneimittel-Forschung, Volume 38, Issue 11, 1 1 1988, Pages 1658-1660 Recombinant interferon gamma in the treatment of metastatic renal cell carcinoma. Results of a phase II trial. Otto U, Conrad S, Schneider AW, Klosterhalfen H
A clinical Phase II study was performed to evaluate the efficacy and safety of treatment with interferon gamma in patients with metastatic renal cell carcinoma. Patients received interferon gamma by two different regimens: 1. 100 micrograms/m2 3x/week i.v. over 4 h every other week--low dose. 2. 500 micrograms/m2 5x/week i.v. over 24 h every other week--high dose--for non-responders to regimen 1. The response rate, duration of response, survival and toxicity in the two regimens were evaluated. T... Abstract
Cited 24 times since 1988 (0.7 per year) source: EuropePMC
Journal of bacteriology, Volume 170, Issue 10, 1 1 1988, Pages 4693-4698 Siderophore-mediated uptake of Fe3+ by the plant growth-stimulating Pseudomonas putida strain WCS358 and by other rhizosphere microorganisms. de Weger LA, van Arendonk JJ, Recourt K, van der Hofstad GA, Weisbeek PJ, Lugtenberg B
Under iron-limited conditions, Pseudomonas putida WCS358 produces a siderophore, pseudobactin 358, which is essential for the plant growth-stimulating ability of this strain. Cells of strain WCS358, provided that they have been grown under Fe3+ limitation, take up 55Fe3+ from the 55Fe3+-labeled pseudobactin 358 complex with Km and Vmax values of 0.23 microM and 0.14 nmol/mg of cell dry weight per min, respectively. Uptake experiments with cells treated with various metabolic inhibitors showed th... Abstract