We focus on understanding the mechanisms of 1) electrical activation & propagation and 2) cellular development & homeostasis in the healthy heart and on how these processes are disrupted in the diseased heart. The purpose of doing so is to use this knowledge for the development of novel, biology-driven therapeutics for human cardiac disease, especially heart rhythm disturbances. Here, one of the main goals is to allow the heart itself to detect and neutralize pathological processes through an integrative approach covering various aspects of biology, mathematics, engineering and medicine.
Ultimately, we believe that our efforts will help to provide a sustainable and comprehensive improvement in the prospects of cardiac health through synthetic biomedicine.
