We believe that our efforts will help to provide a sustainable and comprehensive improvement in the prospects of cardiac health by addressing the (unanswered) needs in knowledge and therapy through the creation of new biology (i.e. synthetic biomedicine) and its integration with emerging technologies.
That is why we focus on understanding the mechanisms of 1) electrical activation & propagation and 2) cellular development & homeostasis in the healthy heart, and on how these processes are disrupted in the diseased heart, in order to use this knowledge for the development of novel, biology-driven therapeutics for human cardiac disease, especially heart rhythm disturbances. Here, one of the key goals is to allow the heart itself to detect and neutralize physiological disturbances through an interdisciplinary approach covering various aspects of biology, mathematics, engineering and medicine.
We are always looking for highly motivated and enthusiastic (PhD) students and postdocs with a genuine interest in cardiac electrophysiology, arrhythmias, cardiac damage & repair and synthetic biology. Feel free to send Dr. Pijnappels an email for more information.