Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7490 results
Cited 79 times since 2010 (5.6 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 11, 20 3 2010, Pages 872-878 The emerging burden of hospital admissions of adults with congenital heart disease. Verheugt CL, Uiterwaal CS, van der Velde ET, Meijboom FJ, Pieper PG, Sieswerda GT, Plokker HW, Grobbee DE, Mulder BJ
Objective: To assess the extent and the characteristics of hospital admissions in registered adult patients with congenital heart disease. Design: Observational cohort study. Setting: The Netherlands. Patients: 5798 adult patients with congenital heart disease from the Dutch CONCOR national registry linked to the Dutch National Medical Registration (Prismant). Main outcome measures: All hospital admissions from the years 2001 up until 2006. Results: During 28 990 patient-years, 2908 patients (50... Abstract
Cited 43 times since 2010 (3.1 per year) source: EuropePMC
Circulation, Volume 121, Issue 17, 19 3 2010, Pages 1887-1895 Early reperfusion during acute myocardial infarction affects ventricular tachycardia characteristics and the chronic electroanatomic and histological substrate. Wijnmaalen AP, Schalij MJ, von der Thüsen JH, Klautz RJ, Zeppenfeld K
Background: Reperfusion therapy during acute myocardial infarction results in myocardial salvage and improved ventricular function but may also influence the arrhythmogenic substrate for ventricular tachycardia (VT). This study used electroanatomic mapping and infarct histology to assess the impact of reperfusion on the substrate and on VT characteristics late after acute myocardial infarction. Methods and results: The study population consisted of 36 patients (32 men; age, 63+/-15 years) referr... Abstract
Cited 246 times since 2010 (17.5 per year) source: EuropePMC
Circulation, Volume 121, Issue 17, 19 3 2010, Pages 1941-1950 Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study. Hellings WE, Peeters W, Moll FL, Piers SR, van Setten J, Van der Spek PJ, de Vries JP, Seldenrijk KA, De Bruin PC, Vink A, Velema E, de Kleijn DP, Pasterkamp G
Background: Identification of patients at risk for primary and secondary manifestations of atherosclerotic disease progression is based mainly on established risk factors. The atherosclerotic plaque composition is thought to be an important determinant of acute cardiovascular events, but no prospective studies have been performed. The objective of the present study was to investigate whether atherosclerotic plaque composition is associated with the occurrence of future vascular events. Methods a... Abstract
Cited 50 times since 2010 (3.6 per year) source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research, Volume 16, Issue 11, 15 3 2010, Pages 3078-3087 A multicenter phase II study of erlotinib and sorafenib in chemotherapy-naive patients with advanced non-small cell lung cancer. Lind JS, Dingemans AM, Groen HJ, Thunnissen FB, Bekers O, Heideman DA, Honeywell RJ, Giovannetti E, Peters GJ, Postmus PE, van Suylen RJ, Smit EF
Purpose: This multicenter, phase II study evaluates the efficacy and safety of erlotinib, an epidermal growth factor receptor (EGFR) inhibitor, plus sorafenib, a multityrosine kinase inhibitor against vascular endothelial growth factor receptors, in patients with previously untreated advanced non-small cell lung cancer (NSCLC). Experimental design: Chemotherapy-naïve patients with stage IIIB/IV NSCLC received erlotinib (150 mg once a day) and sorafenib (400 mg twice a day) until disease progress... Abstract
Cited 13 times since 2010 (0.9 per year) source: EuropePMC
Child: care, health and development, Volume 36, Issue 5, 15 3 2010, Pages 703-708 Short-term changes in parents' resolution regarding their young child's diagnosis of cerebral palsy. Rentinck IC, Ketelaar M, Schuengel C, Stolk J, Lindeman E, Jongmans MJ, Gorter JW
Objective: This study aimed to describe changes in parents' resolution regarding their young child's diagnosis of cerebral palsy over a period of 1 year, and to describe the changes in strategies of resolution. Methods: In this longitudinal study, 38 parents of children with cerebral palsy (mean age 18.4 months, SD = 1.1 at baseline) were followed with the Reaction to Diagnosis Interview, assessing their personal reactions to their child's diagnosis (i.e. resolution status). Chang... Abstract
Cited 17 times since 2010 (1.2 per year) source: EuropePMC
Leukemia research, Volume 34, Issue 10, 14 2 2010, Pages 1275-1281 DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood acute lymphoblastic leukemia. Tumer TB, Yilmaz D, Tanrikut C, Sahin G, Ulusoy G, Arinç E
It is now well established that genetic polymorphisms impairing the DNA repair capacity can disrupt the genomic integrity and potentially modulate individual's susceptibility to various cancers. In this study, we investigated the possible association of X-ray repair cross-complimenting group 1 (XRCC1) Arg399Gln and Arg194Trp variants with the risk of incidence of childhood acute lymphoblastic leukemia (ALL) in Turkish population comprised of 190 healthy controls and 167 ALL patients. For Ar... Abstract
Cited 204 times since 2010 (14.5 per year) source: EuropePMC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Volume 24, Issue 9, 12 2 2010, Pages 3135-3144 Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. Talens RP, Boomsma DI, Tobi EW, Kremer D, Jukema JW, Willemsen G, Putter H, Slagboom PE, Heijmans BT
The prospect of finding epigenetic risk factors for complex diseases would be greatly enhanced if DNA from existing biobanks, which is generally extracted from whole blood, could be used to perform epigenetic association studies. We characterized features of DNA methylation at 16 candidate loci, 8 of which were imprinted, in DNA samples from the Netherlands Twin Register biobank. Except for unmethylated or fully methylated sites, CpG methylation varied considerably in a sample of 30 unrelated in... Abstract
Cited 10 times since 2010 (0.7 per year) source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 40, Issue 1, 10 2 2010, Pages 65-70 Aortic Customize: an in vivo feasibility study of a percutaneous technique for the repair of aortic aneurysms using injectable elastomer. Bosman WM, Vlot J, van der Steenhoven TJ, van den Berg O, Hamming JF, de Vries AC, Brom HL, Jacobs MJ
Objective: This study aimed to test a percutaneous technique for aneurysm-sac filling by means of in situ polymerisation in an in vivo model. Design: Aortic Customize is a new endovascular treatment concept for aortic aneurysms: a non-cross-linked liquid elastomer is injected to fill the aneurysm sac around a balloon-catheter. With this method, a compliant elastomer mould with a patent lumen is created. Material: The formulation used in the experiments consisted of a two-component addition-cure... Abstract
Cited 15 times since 2010 (1.1 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 6, 9 2 2010, Pages 1338-1344 Long-term effects of surgical ventricular restoration with additional restrictive mitral annuloplasty and/or coronary artery bypass grafting on left ventricular function: six-month follow-up by pressure-volume loops. ten Brinke EA, Klautz RJ, Tulner SA, Verwey HF, Bax JJ, Schalij MJ, van der Wall EE, Versteegh MI, Dion RA, Steendijk P
Objectives: Previous studies demonstrated beneficial short-term effects of surgical ventricular restoration on mechanical dyssynchrony and left ventricular function and improved midterm and long-term clinical parameters. However, long-term effects on systolic and diastolic left ventricular function are still largely unknown. Methods: We studied 9 patients with ischemic dilated cardiomyopathy who underwent surgical ventricular restoration with additional restrictive mitral annuloplasty and/or cor... Abstract
Cited 35 times since 2010 (2.5 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 17, Issue 3, 9 2 2010, Pages 470-478 Diagnostic accuracy of 64-slice computed tomography coronary angiography for the detection of in-stent restenosis: a meta-analysis. Carrabba N, Schuijf JD, de Graaf FR, Parodi G, Maffei E, Valenti R, Palumbo A, Weustink AC, Mollet NR, Accetta G, Cademartiri F, Antoniucci D, Bax JJ
Background: We sought to evaluate the diagnostic accuracy of 64-slice multi-detector row computed tomography (MDCT) compared with invasive coronary angiography for in-stent restenosis (ISR) detection. Methods: MEDLINE, Cochrane library, and BioMed Central database searches were performed until April 2009 for original articles. Inclusion criteria were (1) 64-MDCT was used as a diagnostic test for ISR, with >50% diameter stenosis selected as the cut-off criterion for significant ISR, using inva... Abstract
Cited 6 times since 2010 (0.4 per year) source: EuropePMC
Circulation, Volume 121, Issue 13, 1 1 2010, Pages e261-2 Images in cardiovascular medicine. Direct endoscopic visual assessment of a transcatheter aortic valve implantation and performance in the Physioheart, an isolated working heart platform. de Weger A, van Tuijl S, Stijnen M, Steendijk P, de Hart J
Cited 19 times since 2010 (1.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 8, 1 1 2010, Pages 621-624 22q11.2 Deletion Syndrome is under-recognised in adult patients with tetralogy of Fallot and pulmonary atresia. van Engelen K, Topf A, Keavney BD, Goodship JA, van der Velde ET, Baars MJ, Snijder S, Moorman AF, Postma AV, Mulder BJ
Background: Three quarters of patients with 22q11.2 Deletion Syndrome (22q11.2DS) have congenital heart disease (CHD), typically conotruncal heart defects. Although it is currently common practice to test all children with typical CHD for 22q11.2DS, many adult patients have not been tested in the past and therefore 22q11.2DS might be under-recognised in adults. Objectives: To determine the prevalence of 22q11.2DS in adults with tetralogy of Fallot (TOF) and pulmonary atresia (PA)/ventricular sep... Abstract
Cited 4 times since 2010 (0.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 7, 1 1 2010, Pages 560-572 Non-invasive imaging: Non-invasive assessment of coronary artery disease in diabetes. Van de Veire NR, Djaberi R, Schuijf JD, Bax JJ
Cited 25 times since 2010 (1.8 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 3, Issue 4, 1 1 2010, Pages 429-439 Recent developments in heart failure imaging. Marwick TH, Raman SV, Carrió I, Bax JJ
Despite the central role of echocardiography in its primary assessment, heart failure is a condition in which access to multiple cardiovascular imaging modalities is important. A number of important observations relative to this topic have been made in the last year, including the assessment of left ventricular synchrony, myocardial mechanics, heart failure with preserved ejection fraction, metabolic imaging, assessment of myocardial viability, and fusion imaging. Abstract
The Annals of thoracic surgery, Volume 89, Issue 4, 1 1 2010, Pages 1161-1162 Invited commentary. Braun J
Cited 94 times since 2010 (6.7 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 55, Issue 15, 1 1 2010, Pages 1611-1618 Efficacy and safety of mipomersen, an antisense inhibitor of apolipoprotein B, in hypercholesterolemic subjects receiving stable statin therapy. Akdim F, Stroes ES, Sijbrands EJ, Tribble DL, Trip MD, Jukema JW, Flaim JD, Su J, Yu R, Baker BF, Wedel MK, Kastelein JJ
Objectives: The aim of this study was to evaluate the efficacy and safety of mipomersen in hypercholesterolemic subjects taking stable statin therapy. Background: Mipomersen is an apolipoprotein (apo) B synthesis inhibitor that has demonstrated significant reductions in apo B and low-density lipoprotein (LDL) cholesterol in Phase 1 clinical trials in healthy volunteers. Methods: A randomized, placebo-controlled, dose-escalation Phase 2 study was designed to evaluate the effects of mipomersen in... Abstract
Cited 13 times since 2010 (0.9 per year) source: EuropePMC
BMC geriatrics, Volume 10, 1 1 2010, Pages 17 Impact of valvular heart disease on activities of daily living of nonagenarians: the Leiden 85-plus study a population based study. van Bemmel T, Delgado V, Bax JJ, Gussekloo J, Blauw GJ, Westendorp RG, Holman ER
Background: Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown. The present study evaluated the prevalence of significant valvular heart disease and the impact of valvular heart disease on the activities of daily living in community dwelling nonagenarians. Nested within the Leiden 85-plus study, a population... Abstract
Cited 20 times since 2010 (1.4 per year) source: EuropePMC
World journal of surgery, Volume 34, Issue 4, 1 1 2010, Pages 852-860 Factors predicting outcome of total thyroidectomy in young patients with multiple endocrine neoplasia type 2: a nationwide long-term follow-up study. Schreinemakers JM, Vriens MR, Valk GD, de Groot JW, Plukker JT, Bax K, Hamming JF, van der Luijt RB, Aronson DC, Borel Rinkes IH
BACKGROUND Multiple endocrine neoplasia type 2 (MEN 2) is caused by a RET mutation in chromosome 10. All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. METHODS In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), h... Abstract
Cited 16 times since 2010 (1.1 per year) source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 5, Issue 4, 1 1 2010, Pages 554-557 Osteoblastic bone lesions developing during treatment with erlotinib indicate major response in patients with non-small cell lung cancer: a brief report. Lind JS, Postmus PE, Smit EF
Background: The osteoblastic bone flare or response is the paradoxical phenomenon of increase in the quantity and/or density of bone lesions in the presence of well-documented disease response to treatment in other tumor sites. It results from the rapid repair and increased osteoblastic activity in bone metastases responding to therapy and therefore represents treatment efficacy. Nevertheless, no reliable markers can differentiate an osteoblastic flare or response from disease progression. In no... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 26, Issue 6, 1 1 2010, Pages 661-664 Positron emission tomography; viable tool in patients pre-CABG? van der Wall EE, Siebelink HM, Scholte AJ, Bax JJ