Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7490 results
Cited 12 times since 1997 (0.5 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 114, Issue 5, 1 1 1997, Pages 844-846 Switch back: using the pulmonary autograft to replace the aortic valve after arterial switch operation. Hazekamp MG, Schoof PH, Suys BE, Hutter PA, Meijboom EJ, Ottenkamp J, Huysmans HA
Cited 16 times since 1997 (0.6 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 17, Issue 10, 1 1 1997, Pages 2177-2187 Involvement of calcium and G proteins in the acute release of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells. van den Eijnden-Schrauwen Y, Atsma DE, Lupu F, de Vries RE, Kooistra T, Emeis JJ
In this study, we investigated the role of Ca2+ and G proteins in thrombin-induced acute release (regulated secretion) of tissue-type plasminogen activator (TPA) and von Willebrand factor (vWF), using a previously described system of primary human umbilical vein endothelial cells (HUVECs). The acute release of TPA and vWF, as induced by alpha-thrombin, was almost zero after chelation of Ca2+i, showing that an increase in [Ca2+]i was required. It did not matter whether the increase in [Ca2+]i cam... Abstract
Cited 29 times since 1997 (1.1 per year) source: EuropePMC
European journal of cancer (Oxford, England : 1990), Volume 33, Issue 11, 1 1 1997, Pages 1759-1766 Role of recombinant interferon-gamma maintenance in responding patients with small cell lung cancer. A randomised phase III study of the EORTC Lung Cancer Cooperative Group. van Zandwijk N, Groen HJ, Postmus PE, Burghouts JT, ten Velde GP, Ardizzoni A, Smith IE, Baas P, Sahmoud T, Kirkpatrick A, Dalesio O, Giaccone G
This study was undertaken to determine if recombinant interferon-gamma (rIFN-gamma) given every other day as maintenance therapy could prolong the survival of patients with small cell lung cancer (SCLC) who achieved a complete or nearly-complete response to induction therapy. A secondary endpoint was to assess the toxicity of alternate day doses of this treatment. One hundred and seventy seven patients in complete or nearly-complete response following chemotherapy with or without thoracic radiot... Abstract
Cited 1 times since 1997 (0 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 141, Issue 40, 1 1 1997, Pages 1924-1928 [Spontaneous pneumothorax in young women: possible lymphangioleiomyomatosis]. Louis H, Los H, Lagendijk JH, de Graaff CS, Postmus PE
(Recurrent) pneumothorax developed spontaneously in three women aged 33, 35 and 36 years, two of whom were pregnant. Morbid-anatomical examination of lung biopsy samples in two of them revealed proliferation of smooth muscle cells which through infiltration of pleura, septa, and alveoli had led to loss of pulmonary parenchyma and formation of cystic lesions; the cystic lesions were visible in a CT scan in all three patients. The diagnosis in 2 patients was 'lymphangioleiomyomatosis'; t... Abstract
Cited 3 times since 1997 (0.1 per year) source: EuropePMC
The International journal of biological markers, Volume 12, Issue 4, 1 1 1997, Pages 162-167 The diagnostic value of pretreatment serum LDH in patients with limited disease small-cell lung carcinoma. Stokkel MP, Van Eck-Smit BL, Zwinderman AH, Willems LN, Pauwels EK
Background: In patients with limited disease SCLC, the overall survival is still poor. Therefore, a retrospective study was performed involving 48 patients with limited disease SCLC to select a parameter which can identify prognostic subgroups at the time of diagnosis. Materials and methods: Follow-up ranged from 3 to 96 months, during which period 38 patients died. Based on clinical outcome, patients were classified into 3 groups: complete remission (CR) (n = 16), local recurrence (LOC) (n = 7)... Abstract
Cited 106 times since 1997 (4 per year) source: EuropePMC
Circulation, Volume 96, Issue 8, 1 1 1997, Pages 2573-2577 Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Kluijtmans LA, Kastelein JJ, Lindemans J, Boers GH, Heil SG, Bruschke AV, Jukema JW, van den Heuvel LP, Trijbels FJ, Boerma GJ, Verheugt FW, Willems F, Blom HJ
Background: Hyperhomocysteinemia, an independent and graded risk factor for coronary artery disease (CAD), may result from both environmental and hereditary factors. Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of methylenetetrahydrofolate to methyltetrahydrofolate, the methyl donor in the remethylation of homocysteine to methionine. A 677C-->T mutation in the MTHFR gene has been associated with elevated homocysteine concentrations in homozygous (+/+) individuals. Meth... Abstract
Cited 6 times since 1997 (0.2 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 114, Issue 4, 1 1 1997, Pages 560-567 Acute elevation of coronary venous pressure does not affect left ventricular contractility in the normal and stressed swine heart: implications for the Fontan operation. Klautz RJ, van Rijk-Zwikker GL, Steendijk P, Wilde J, Teitel DF, Baan J
Objective: After the Fontan operation the right atrium and, thus, the coronary sinus are connected to the pulmonary arterial system, which causes the coronary venous pressure to increase. We investigated the acute effects of elevation of coronary venous pressure on baseline hemodynamics, coronary venous flow, and left ventricular contractility. Methods: In acutely instrumented pigs, during complete right heart bypass and during constant cardiac output, pressure in the right atrium, right ventric... Abstract
Cited 10 times since 1997 (0.4 per year) source: EuropePMC
AJR. American journal of roentgenology, Volume 169, Issue 4, 1 1 1997, Pages 995-999 Biventricular function in patients with nonischemic right ventricle tachyarrhythmias assessed with MR imaging. Kayser HW, Schalij MJ, van der Wall EE, Stoel BC, de Roos A
Cited 93 times since 1997 (3.5 per year) source: EuropePMC
The Journal of infectious diseases, Volume 176, Issue 3, 1 1 1997, Pages 740-747 Antileukoprotease: an endogenous protein in the innate mucosal defense against fungi. Tomee JF, Hiemstra PS, Heinzel-Wieland R, Kauffman HF
Previous studies have suggested that endogenous protease inhibitors may participate in the mucosal host defense. Antileukoprotease (ALP) is an important protease inhibitor found on various mucosal surfaces, including those of the respiratory and genital tracts. This study reports on the antimicrobial activity of recombinant (r) ALP toward the human fungal pathogens Aspergillus fumigatus and Candida albicans. rALP expressed pronounced fungicidal activity toward metabolically active A. fumigatus c... Abstract
Cited 50 times since 1997 (1.9 per year) source: EuropePMC
Laboratory investigation; a journal of technical methods and pathology, Volume 77, Issue 3, 1 1 1997, Pages 213-220 Detection of cytokeratin-19 transcripts by reverse transcriptase-polymerase chain reaction in lung cancer cell lines and blood of lung cancer patients. Dingemans AM, Brakenhoff RH, Postmus PE, Giaccone G
Conflicting results have been reported on the use of cytokeratin-19 (CK-19) in the detection of tumor cells in the peripheral blood of patients with solid tumors. We investigated the expression of CK-19 in lung cancer cell lines and in human lung tumor samples using a nested reverse transcriptase (RT)-PCR to determine the sensitivity and specificity of this method. In addition, blood samples of lung cancer patients and healthy controls were analyzed for the presence of CK-19 transcripts. Amplifi... Abstract
Cited 35 times since 1997 (1.3 per year) source: EuropePMC
Chest, Volume 112, Issue 3, 1 1 1997, Pages 640-645 The effect of right ventricular hypertrophy on left ventricular ejection fraction in pulmonary emphysema. Vonk Noordegraaf A, Marcus JT, Roseboom B, Postmus PE, Faes TJ, de Vries PM
Study objective: The development of right ventricular (RV) hypertrophy in emphysema is accompanied by involvement of the left ventricle (LV) and its systolic function. Our objective was to study the relation between RV hypertrophy and LV ejection fraction in emphysema by means of MRI. Patients: Ten emphysematous patients (FEV1, 0.99+/-0.32 L; FEV1/vital capacity (VC), 0.32+/-0.11 [mean+/-SD]) and 10 age-matched control subjects were included. Exclusion criteria were any history of systemic hyper... Abstract
Cited 1 times since 1997 (0 per year) source: EuropePMC
International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, Volume 20, Issue 3, 1 1 1997, Pages 289-301 The quality of life of people with mental retardation: in search of an adequate approach. Vreeke GJ, Janssen CG, Resnick S, Stolk J
There is a lack of instruments that measure the quality of life of people with mental retardation. These types of instruments could be used in order to give an indication of the quality of care they receive. At the moment we are developing an instrument that measures quality of life. Our first task is to find an adequate definition of 'quality of life'. In this article an attempt is made to define this term as it relates to people with mental retardation. Starting from literature in th... Abstract
Cited 2 times since 1997 (0.1 per year) source: EuropePMC
The Journal of pathology, Volume 183, Issue 1, 1 1 1997, Pages 99-104 Identification of host and donor cells in porcine homograft heart valve explants by fluorescence in situ hybridization. Braun J, Hazekamp MG, Koolbergen DR, Sugihara H, Goffin YA, Huysmans HA, Cornelisse CJ
The pathogenesis of the primary tissue degeneration that limits the life-span of aortic and pulmonary homografts has still not been revealed. Histopathological studies on homograft explants have not given definitive insight into the eventual fate of donor cells, nor have they demonstrated the assumed importance of host cell ingrowth into the graft tissue. In this experimental study, fluorescence in situ hybridization (FISH) is introduced as a new approach to examine the distribution of host and... Abstract
Investigative radiology, Volume 32, Issue 9, 1 1 1997, Pages 540-549 Quantitative assessment of the presence of a single leg separation in Björk-Shiley convexoconcave prosthetic heart valves. Vrooman HA, Maliepaard C, van der Linden LP, Jessurun ER, Ludwig JW, Plokker HW, Schalij MJ, Weeda HW, Laufer JL, Huysmans HA, Reiber JH
Rationale and objectives: The authors developed an analytic software package for the objective and reproducible assessment of a single leg separation (SLS) in the outlet strut of Björk-Shiley convexoconcave (BSCC) prosthetic heart valves. Methods: The radiographic cinefilm recordings of 18 phantom valves (12 intact and 6 SLS) and of 43 patient valves were acquired. After digitization of regions of interest in a cineframe, several processing steps were carried out to obtain a one-dimensional corr... Abstract
Cited 31 times since 1997 (1.2 per year) source: EuropePMC
European heart journal, Volume 18, Issue 9, 1 1 1997, Pages 1505-1513 Comparison of echocardiography with magnetic resonance imaging in the assessment of the athlete's heart. Pluim BM, Beyerbacht HP, Chin JC, Zwinderman A, Van der Laarse A, De Roos A, Vliegen HW, Van der Wall EE
Aim: The purpose of the study was to compare the accuracy of M-mode echocardiography and two different two-dimensional echocardiographic approaches in the assessment of left ventricular mass and volumes in endurance-trained and strength-trained athletes, using magnetic resonance imaging as reference standard. Methods and results: We studied 19 athletes and 10 untrained control subjects, M-mode and two-dimensional echocardiography were compared to magnetic resonance imaging. M-mode echocardiograp... Abstract
Cited 5 times since 1997 (0.2 per year) source: EuropePMC
Circulation, Volume 96, Issue 3, 1 1 1997, Pages 1025-1030 Hemodynamic effects of chronic prenatal ventricular pacing for the treatment of complete atrioventricular block. Liddicoat JR, Klein JR, Reddy VM, Klautz RJ, Teitel DF, Hanley FL
Background: Increasing the heart rate of the fetus with cardiac failure caused by complete AV block (CAVB) may allow delivery of a full-term, stable neonate with preserved ventricular function. Direct fetal pacing may be a feasible method to achieve this, but the effect of pacing on the structure and function of the rapidly developing fetal heart is unknown. Methods and results: CAVB was created in fetal lambs at 80% gestation by cryoablating the AV node. Epicardial ventricular pacing at 130 bpm... Abstract
Cited 94 times since 1997 (3.5 per year) source: EuropePMC
American journal of respiratory and critical care medicine, Volume 156, Issue 2 Pt 1, 1 1 1997, Pages 609-616 Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. Grünberg K, Smits HH, Timmers MC, de Klerk EP, Dolhain RJ, Dick EC, Hiemstra PS, Sterk PJ
Asthma exacerbations are often associated with respiratory virus infections, particularly with rhinovirus. In the present study we investigated the effect of experimental rhinovirus 16 (RV16) infection on airway inflammation as assessed by analysis of hypertonic saline-induced sputum. Twenty-seven nonsmoking atopic, mildly asthmatic subjects participated in a placebo-controlled parallel study. RV16 (n = 19) or its diluent (n = 8) was nasally administered. Sputum inductions were performed at entr... Abstract
Cited 37 times since 1997 (1.4 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 64, Issue 2, 1 1 1997, Pages 521-525 Modified ultrafiltration after cardiopulmonary bypass in pediatric cardiac surgery. Draaisma AM, Hazekamp MG, Frank M, Anes N, Schoof PH, Huysmans HA
Background: Cardiopulmonary bypass in children results in considerable water retention, especially in neonates and small infants. Dilution of plasma proteins increases water loss into the extravascular compartments. Excessive total body water may prolong ventilatory support and may contribute to a prolongation of intensive care convalescence. After discontinuation of cardiopulmonary bypass, modified ultrafiltration can be used to withdraw plasma water from the total circulating volume. Methods:... Abstract
Cited 56 times since 1997 (2.1 per year) source: EuropePMC
Journal of leukocyte biology, Volume 62, Issue 2, 1 1 1997, Pages 217-226 Effect of neutrophil serine proteinases and defensins on lung epithelial cells: modulation of cytotoxicity and IL-8 production. Van Wetering S, Mannesse-Lazeroms SP, Dijkman JH, Hiemstra PS
Neutrophil accumulation in the lung may contribute to tissue injury as observed in inflammatory diseases. Both oxidative and non-oxidative mechanisms are involved in neutrophil-mediated tissue injury. Non-oxidative mechanisms include the release of neutrophil granule proteins such as the serine proteinases elastase and cathepsin G, and the non-enzymatic defensins. Because stimulated neutrophils are thought to release their products simultaneously, we investigated possible interactions between pu... Abstract
Cited 34 times since 1997 (1.3 per year) source: EuropePMC
Journal of clinical epidemiology, Volume 50, Issue 8, 1 1 1997, Pages 881-890 Antimicrobial treatment in acute maxillary sinusitis: a meta-analysis. de Bock GH, Dekker FW, Stolk J, Springer MP, Kievit J, van Houwelingen JC
Objective: The aims of this study were to assess which antibiotic is most effective in the treatment of acute maxillary sinusitis in otherwise healthy adults and adolescents, and which has the fewest side effects. Design: To assess the short-term effects of antimicrobial treatments, a meta-analysis was performed using Mantel-Haenszel procedures on 16 comparative, randomized studies with a total number of 3358 patients. No placebo-controlled studies were available. Antimicrobial treatments were c... Abstract