Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7490 results
Cited 11 times since 2009 (0.8 per year) source: EuropePMC
Coronary artery disease, Volume 20, Issue 7, 1 1 2009, Pages 462-466 Value of contrast echocardiography for left ventricular thrombus detection postinfarction and impact on antithrombotic therapy. Siebelink HM, Scholte AJ, Van de Veire NR, Holman ER, Nucifora G, van der Wall EE, Bax JJ
Introduction: Conventional echocardiography is often inconclusive for the presence or the absence of left ventricular (LV) thrombus. Contrast echocardiography could have additional diagnostic and therapeutic significance. This analysis investigated the value of contrast echocardiography for LV thrombus detection in patients postinfarction and the impact on choice of antithrombotic therapy. Methods: From a cohort of 991 patients undergoing routine echocardiography postinfarction, 156 patients who... Abstract
Cited 23 times since 2009 (1.6 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 95, Issue 22, 1 1 2009, Pages 1881-1890 Real-time three dimensional echocardiography: current and future clinical applications. Marsan NA, Tops LF, Nihoyannopoulos P, Holman ER, Bax JJ
Cited 27 times since 2009 (1.9 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 11 Suppl 5, 1 1 2009, Pages v46-57 Why, how and when do we need to optimize the setting of cardiac resynchronization therapy? Bertini M, Delgado V, Bax JJ, Van de Veire NR
Current cardiac resynchronization therapy (CRT) devices allow manipulation of the atrioventricular (AV) and interventricular (VV) timings in order to maximize the left ventricular (LV) performance. Multiple echocardiographic and non-echocardiographic methods have been proposed to optimize AV and VV intervals but no consensus has been reached on which methodology should preferably be used. Furthermore, different physiologic conditions, such as rest and exercise, may markedly change LV loading con... Abstract
The Annals of thoracic surgery, Volume 88, Issue 5, 1 1 2009, Pages 1504-1505 Invited commentary. Braun J
Cited 10 times since 2009 (0.7 per year) source: EuropePMC
Molecular phylogenetics and evolution, Volume 54, Issue 2, 28 4 2009, Pages 336-343 Preliminary insight into the age and origin of the Labeobarbus fish species flock from Lake Tana (Ethiopia) using the mtDNA cytochrome b gene. de Graaf M, Megens HJ, Samallo J, Sibbing F
The high diversity of Cyprinid fish in Ethiopia's Lake Tana appears to be an example of ecological differentiation and assortative mating leading to rapid sympatric speciation. Lake Tana's Labeobarbus species flock consists of 15 morphological and ecological distinct species. This is the first attempt to determine the age and origin and inter-species relationships of Lake Tana's Labeobarbus species using the mtDNA cytochrome b gene. Analysis of cytchrome b sequences shows that Lak... Abstract
Cited 24 times since 2009 (1.7 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 3, 28 4 2009, Pages 213-219 Single-beat estimation of the left ventricular end-diastolic pressure-volume relationship in patients with heart failure. Ten Brinke EA, Burkhoff D, Klautz RJ, Tschöpe C, Schalij MJ, Bax JJ, van der Wall EE, Dion RA, Steendijk P
Aims: To test a method to predict the end-diastolic pressure-volume relationship (EDPVR) from a single beat in patients with heart failure. Methods and results: Patients (New York Heart Association class III-IV) scheduled for mitral annuloplasty (n=9) or ventricular restoration (n=10) and patients with normal left ventricular function undergoing coronary artery bypass grafting (n=12) were instrumented with pressure-conductance catheters to measure pressure-volume loops before and after surgery.... Abstract
Cited 33 times since 2009 (2.3 per year) source: EuropePMC
Radiology, Volume 253, Issue 3, 28 4 2009, Pages 734-744 CT coronary angiography in patients suspected of having coronary artery disease: decision making from various perspectives in the face of uncertainty. Genders TS, Meijboom WB, Meijs MF, Schuijf JD, Mollet NR, Weustink AC, Pugliese F, Bax JJ, Cramer MJ, Krestin GP, de Feyter PJ, Hunink MG
Purpose: To determine the cost-effectiveness of computed tomographic (CT) coronary angiography as a triage test, performed prior to conventional coronary angiography, by using a Markov model. Materials and methods: A Markov model was used to analyze the cost-effectiveness of CT coronary angiography performed as a triage test prior to conventional coronary angiography from the perspective of the patient, physician, hospital, health care system, and society by using recommendations from the United... Abstract
Cited 15 times since 2009 (1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 6, 26 4 2009, Pages 425-431 Combined non-invasive anatomical and functional assessment with MSCT and MRI for the detection of significant coronary artery disease in patients with an intermediate pre-test likelihood. van Werkhoven JM, Heijenbrok MW, Schuijf JD, Jukema JW, van der Wall EE, Schreur JH, Bax JJ
Objectives: To compare magnetic resonance myocardial perfusion imaging (MRI) with anatomical assessment by multislice computed tomography (MSCT) coronary angiography and conventional coronary angiography. Design and patients: In this prospective study, 53 patients (60% male, average age 57+/-9 years, 83% intermediate pre-test likelihood) underwent 1.5 T MRI, 64-slice MSCT and conventional coronary angiography. Main outcome measures: The presence of significant stenosis (>or=50% luminal narrow... Abstract
Cited 21 times since 2009 (1.4 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 95, Issue 24, 20 3 2009, Pages 1990-1996 Plaque type and composition as evaluated non-invasively by MSCT angiography and invasively by VH IVUS in relation to the degree of stenosis. van Velzen JE, Schuijf JD, de Graaf FR, Nucifora G, Pundziute G, Jukema JW, Schalij MJ, Kroft LJ, de Roos A, Reiber JH, van der Wall EE, Bax JJ
Background: Imaging of coronary plaques has traditionally focused on evaluating degree of stenosis, as the risk for adverse cardiac events increases with stenosis severity. However, the relation between plaque composition and severity of stenosis remains largely unknown. Objective: To assess plaque composition (non-invasively by multislice computed tomography (MSCT) angiography and invasively by virtual histology intravascular ultrasound (VH IVUS)) in relation to degree of stenosis. Methods: 78... Abstract
Cited 11 times since 2009 (0.8 per year) source: EuropePMC
Acta anaesthesiologica Scandinavica, Volume 54, Issue 4, 15 3 2009, Pages 470-478 Xenon and isoflurane improved biventricular function during right ventricular ischemia and reperfusion. Hein M, Roehl AB, Baumert JH, Bleilevens C, Fischer S, Steendijk P, Rossaint R
Background: Although anesthetics have some cardioprotective properties, these benefits are often counterbalanced by their negative inotropic effects. Xenon, on the other hand, does not influence myocardial contractility. Thus, xenon may be a superior treatment for the maintenance of global hemodynamics, especially during right ventricular ischemia, which is generally characterized by a high acute complication rate. Methods: The effects of 70 vol% xenon and 0.9 vol% isoflurane on biventricular fu... Abstract
Cited 19 times since 2009 (1.3 per year) source: EuropePMC
Circulation, Volume 120, Issue 17, 12 2 2009, Pages 1687-1694 Short-term hemodynamic effects of cardiac resynchronization therapy in patients with heart failure, a narrow QRS duration, and no dyssynchrony. Williams LK, Ellery S, Patel K, Leyva F, Bleasdale RA, Phan TT, Stegemann B, Paul V, Steendijk P, Frenneaux M
Background: Cardiac resynchronization therapy produces both short-term hemodynamic and long-term symptomatic/mortality benefits in symptomatic heart failure patients with a QRS duration >120 ms. This is conventionally believed to be due principally to relief of dyssynchrony, although we recently showed that relief of external constraint to left ventricular filling may also play a role. In this study, we evaluated the short-term hemodynamic effects in symptomatic patients with a QRS duration Abstract
Cited 55 times since 2009 (3.8 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 1, 9 2 2009, Pages 15-23 Viability assessment with global left ventricular longitudinal strain predicts recovery of left ventricular function after acute myocardial infarction. Mollema SA, Delgado V, Bertini M, Antoni ML, Boersma E, Holman ER, Stokkel MP, van der Wall EE, Schalij MJ, Bax JJ
Background: The extent of viable myocardial tissue is recognized as a major determinant of recovery of left ventricular (LV) function after myocardial infarction. In the current study, the role of global LV strain assessed with novel automated function imaging (AFI) to predict functional recovery after acute infarction was evaluated. Methods and results: A total of 147 patients (mean age, 61+/-11 years) admitted for acute myocardial infarction were included. All patients underwent 2D echocardiog... Abstract
Cited 20 times since 2009 (1.4 per year) source: EuropePMC
Journal of neurology, Volume 257, Issue 3, 8 2 2009, Pages 447-451 The heart in sporadic inclusion body myositis: a study in 51 patients. Cox FM, Delgado V, Verschuuren JJ, Ballieux BE, Bax JJ, Wintzen AR, Badrising UA
The purpose of this study was to explore the prevalence and nature of cardiac abnormalities in sporadic inclusion body myositis (sIBM). Fifty-one sIBM patients were cross-sectionally studied using history-taking, physical examination, measurements of serum creatine kinase activity, the MB fraction (CK-MB), cardiac troponin T (cTnT) and I (cTnI), a 12-lead electrocardiogram (ECG) and 2-dimensional echocardiography. Present cardiac history was abnormal in 12 (24%) out of 51 patients, 12 (24%) pati... Abstract
Cited 69 times since 2009 (4.7 per year) source: EuropePMC
American heart journal, Volume 158, Issue 5, 3 1 2009, Pages 836-844 Incremental value of 2-dimensional speckle tracking strain imaging to wall motion analysis for detection of coronary artery disease in patients undergoing dobutamine stress echocardiography. Ng AC, Sitges M, Pham PN, Tran da T, Delgado V, Bertini M, Nucifora G, Vidaic J, Allman C, Holman ER, Bax JJ, Leung DY
Background: Interpretation of dobutamine stress echocardiogram (DSE) is often subjective and requires expert training. The purposes of this study was to determine optimal cutoff values for longitudinal, circumferential, and radial strains at peak DSE for detection of significant stenoses on coronary angiography and to investigate incremental value of combining strain measurements to wall motion analysis. Methods: In this multicenter study, 102 patients underwent concomitant DSE and coronary angi... Abstract
Cited 58 times since 2009 (4 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 297, Issue 6, 2 1 2009, Pages H2154-60 RC time constant of single lung equals that of both lungs together: a study in chronic thromboembolic pulmonary hypertension. Saouti N, Westerhof N, Helderman F, Marcus JT, Stergiopulos N, Westerhof BE, Boonstra A, Postmus PE, Vonk-Noordegraaf A
The product of resistance, R, and compliance, C (RC time), of the entire pulmonary circulation is constant. It is unknown if this constancy holds for individual lungs. We determined R and C in individual lungs in chronic thromboembolic pulmonary hypertension (CTEPH) patients where resistances differ between both lungs. Also, the contribution of the proximal pulmonary arteries (PA) to total lung compliance was assessed. Patients (n=23) were referred for the evaluation of CTEPH. Pressure was measu... Abstract
Cited 1 times since 2009 (0.1 per year) source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 4, Issue 10, 1 1 2009, Pages 1291-1292 A nonresponding small cell lung carcinoma. Pronk NB, Polman AJ, Sterk L, Oosterhuis JW, Smit EF
We present a case with limited disease small cell lung carcinoma with persisting disease and a troublesome syndrome of inappropriate antidiuretic hormone, despite concurrent chemoradiotherapy and second-line chemotherapy. To gain local control, a lobectomy was performed. Abstract
Cited 86 times since 2009 (5.9 per year) source: EuropePMC
Investigative radiology, Volume 44, Issue 10, 1 1 2009, Pages 669-675 Flow assessment through four heart valves simultaneously using 3-dimensional 3-directional velocity-encoded magnetic resonance imaging with retrospective valve tracking in healthy volunteers and patients with valvular regurgitation. Roes SD, Hammer S, van der Geest RJ, Marsan NA, Bax JJ, Lamb HJ, Reiber JH, de Roos A, Westenberg JJ
Objectives: To validate 3-dimensional (3D) 3-directional velocity-encoded (VE) magnetic resonance imaging (MRI) for flow assessment through all 4 heart valves simultaneously with retrospective valve-tracking during off-line analysis in healthy volunteers and in patients with valvular regurgitation. Material and methods: Three-dimensional 3-directional VE MRI was performed in 22 healthy volunteers and in 29 patients with ischemic cardiomyopathy who were suspected of valvular regurgitation and net... Abstract
Cited 123 times since 2009 (8.4 per year) source: EuropePMC
Annals of internal medicine, Volume 151, Issue 8, 1 1 2009, Pages 517-527 Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial. Lapperre TS, Snoeck-Stroband JB, Gosman MM, Jansen DF, van Schadewijk A, Thiadens HA, Vonk JM, Boezen HM, Ten Hacken NH, Sont JK, Rabe KF, Kerstjens HA, Hiemstra PS, Timens W, Postma DS, Sterk PJ, Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease Study Group
Background: Inhaled corticosteroids (ICSs) and long-acting beta(2)-agonists (LABAs) are used to treat moderate to severe chronic obstructive pulmonary disease (COPD). Objective: To determine whether long-term ICS therapy, with and without LABAs, reduces inflammation and improves pulmonary function in COPD. Design: Randomized, placebo-controlled trial. (ClinicalTrials.gov registration number: NCT00158847) Setting: 2 university medical centers in The Netherlands. Patients: 114 steroid-naive curren... Abstract
Cited 89 times since 2009 (6.1 per year) source: EuropePMC
European journal of heart failure, Volume 11, Issue 10, 1 1 2009, Pages 929-936 Independent relationship of left atrial size and mortality in patients with heart failure: an individual patient meta-analysis of longitudinal data (MeRGE Heart Failure). Rossi A, Temporelli PL, Quintana M, Dini FL, Ghio S, Hillis GS, Klein AL, Marsan NA, Prior DL, Yu CM, Poppe KK, Doughty RN, Whalley GA, MeRGE Heart Failure Collaborators
Aims: Left atrial (LA) size is considered a marker of poor prognosis in heart failure (HF) patients. Prior studies have recruited relatively few subjects limiting their power to adequately analyse the interaction between LA size, left ventricular (LV) systolic and diastolic function, and prognosis. Method and results: The MeRGE collaboration combines prospective data from 18 studies in HF patients. In this analysis of data from 1157 patients, the primary endpoint was death or hospitalization for... Abstract
Cited 18 times since 2009 (1.2 per year) source: EuropePMC
The American journal of cardiology, Volume 104, Issue 8, 1 1 2009, Pages 1041-1046 Usefulness of carotid intima-media thickness in patients with diabetes mellitus as a predictor of coronary artery disease. Djaberi R, Schuijf JD, de Koning EJ, Rabelink TJ, Smit JW, Kroft LJ, Pereira AM, Scholte AJ, Spaans M, Romijn JA, de Roos A, van der Wall EE, Jukema JW, Bax JJ
Identification of asymptomatic patients with diabetes mellitus (DM) at increased risk for coronary artery disease (CAD) remains a challenge. Carotid intima-media thickness (CIMT) has been proposed as a surrogate marker for CAD but only limited data are available. The purpose of the study was to evaluate the potential of CIMT for prediction of CAD in asymptomatic patients with DM. Prospectively, CIMT of the left and right common carotid arteries was assessed by B-mode ultrasound in 150 asymptomat... Abstract