Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7496 results
Cited 13 times since 2006 (0.7 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 17, Issue 1, 1 1 2006, Pages 101-103 Acceleration-dependent left bundle branch block with severe left ventricular dyssynchrony results in acute heart failure: are there more patients who benefit from cardiac resynchronization therapy? Zeppenfeld K, Schalij MJ, Bleeker GB, Holman ER, Bax JJ
Cardiac resynchronization therapy (CRT) has been proposed to improve hemodynamics in patients with heart failure and left bundle branch block (LBBB) by resynchronization of left ventricular (LV) dyssynchrony. The current report concerns a patient with narrow QRS complex without LV dyssynchrony who experienced an acute exacerbation of heart failure following exercise. Careful analysis revealed that an increase of heart rate induced acceleration-dependent LBBB with severe LV dyssynchrony and mitra... Abstract
Cited 25 times since 2006 (1.4 per year) source: EuropePMC
ASAIO journal (American Society for Artificial Internal Organs : 1992), Volume 52, Issue 1, 1 1 2006, Pages 4-8 Modeling ventricular function during cardiac assist: does time-varying elastance work? Vandenberghe S, Segers P, Steendijk P, Meyns B, Dion RA, Antaki JF, Verdonck P
The time-varying elastance theory of Suga et al. is widely used to simulate left ventricular function in mathematical models and in contemporary in vitro models. We investigated the validity of this theory in the presence of a left ventricular assist device. Left ventricular pressure and volume data are presented that demonstrate the heart-device interaction for a positive-displacement pump (Novacor) and a rotary blood pump (Medos). The Novacor was implanted in a calf and used in fixed-rate mode... Abstract
Cited 58 times since 2006 (3.2 per year) source: EuropePMC
The European respiratory journal, Volume 27, Issue 1, 1 1 2006, Pages 60-64 Increased number of B-cells in bronchial biopsies in COPD. Gosman MM, Willemse BW, Jansen DF, Lapperre TS, van Schadewijk A, Hiemstra PS, Postma DS, Timens W, Kerstjens HA, Groningen and Leiden Universities Corticosteroids in Obstructive Lung Disease Study Group
Recently, it has been shown that the accumulated volume of B-cells in small airways is increased in chronic obstructive pulmonary disease (COPD) Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages 3 and 4. Little is known about the number of B-cells in central airways in COPD. The present authors hypothesised that the number of B-cells in bronchial biopsies of large airways is higher in patients with COPD than in controls without airflow limitation and higher in more severe COPD... Abstract
Critical care medicine, Volume 34, Issue 1, 1 1 2006, Pages 255-257 The role of nitric oxide signaling in sepsis-induced myocardial dysfunction. Steendijk P
Cited 31 times since 2006 (1.7 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 33, Issue 1, 1 1 2006, Pages 93-104 Diagnostic and prognostic value of non-invasive imaging in known or suspected coronary artery disease. Schuijf JD, Poldermans D, Shaw LJ, Jukema JW, Lamb HJ, de Roos A, Wijns W, van der Wall EE, Bax JJ
The role of non-invasive imaging techniques in the evaluation of patients with suspected or known coronary artery disease (CAD) has increased exponentially over the past decade. The traditionally available imaging modalities, including nuclear imaging, stress echocardiography and magnetic resonance imaging (MRI), have relied on detection of CAD by visualisation of its functional consequences (i.e. ischaemia). However, extensive research is being invested in the development of non-invasive anatom... Abstract
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 1, Issue 1, 1 1 2006, Pages 69-70 Where is the heart after left-sided pneumonectomy? Smulders SA, van den Bosch HC, Post JC, Vonk Noordegraaf A, Postmus PE
Cited 17 times since 2006 (0.9 per year) source: EuropePMC
Crisis, Volume 27, Issue 2, 1 1 2006, Pages 77-81 High rates of suicide and attempted suicide using pesticides in Nickerie, Suriname, South America. Graafsma T, Kerkhof A, Gibson D, Badloe R, van de Beek LM
Suicide and attempted suicide are identified as a serious mental health problem in Suriname, especially in the district of Nickerie. An epidemiological study in the Nickerie catchment area revealed high rates of suicide (48 per 100,000) and attempted suicide (207 per 100,000) on average in the years 2000-2004. Particularly remarkable is the high number of attempted suicides among males (49%), and the use of pesticides in both fatal (55%) and nonfatal suicidal behavior (44%). Probably this high i... Abstract
Cited 20 times since 2006 (1.1 per year) source: EuropePMC
International journal of chronic obstructive pulmonary disease, Volume 1, Issue 2, 1 1 2006, Pages 151-160 Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management. Stolk J, Seersholm N, Kalsheker N
The Alpha One International Registry (AIR), a multinational research program focused on alpha1-antitrypsin (AAT) deficiency, was formed in response to a World Health Organization recommendation. Each of the nearly 20 participating countries maintains a national registry of patients with AAT deficiency and contributes to an international database located in Malmö, Sweden. This database is designed to increase understanding of AAT deficiency. Additionally, AIR members are engaged in active, wide-r... Abstract
Cited 1 times since 2006 (0.1 per year) source: EuropePMC
Heart rhythm, Volume 3, Issue 1, 1 1 2006, Pages 50-51 Endoscopic fiberoptic balloon catheter: a new step in imaging-guided anatomically based catheter ablation for atrial fibrillation? Tops LF, Schalij MJ, Bax JJ
Cited 6 times since 2005 (0.3 per year) source: EuropePMC
The American journal of cardiology, Volume 97, Issue 4, 22 4 2005, Pages 462-465 Enhanced sensitivity of dobutamine stress echocardiography by observing wall motion abnormalities during the recovery phase after acute beta-blocker administration. Karagiannis SE, Bax JJ, Elhendy A, Feringa HH, Cokkinos DV, van Domburg R, Simoons M, Poldermans D
Dobutamine stress echocardiography (DSE) has a modest sensitivity for detecting single-vessel coronary artery disease (CAD). This study assessed the additional diagnostic value of new or worsening wall motion abnormalities during recovery after acute administration of beta blockers. The study population consisted of 200 patients (mean 59 +/- 11 years of age, 144 men), who underwent DSE. Images were acquired at rest, low dose, peak dose, and during recovery. Patients received intravenous metoprol... Abstract
Cited 52 times since 2005 (2.8 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 22, Issue 1, 13 2 2005, Pages 63-80 Imaging techniques in nuclear cardiology for the assessment of myocardial viability. Slart RH, Bax JJ, van Veldhuisen DJ, van der Wall EE, Dierckx RA, Jager PL
The assessment of myocardial viability has become an important aspect of the diagnostic and prognostic work-up of patients with ischemic cardiomyopathy. Although revascularization may be considered in patients with sufficient viable myocardium, patients with predominantly scar tissue should be treated medically. Patients with left ventricular dysfunction who have viable myocardium are the patients at highest risk because of the potential for ischemia but at the same time benefit most from revasc... Abstract
Cited 4 times since 2005 (0.2 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 22, Issue 1, 10 2 2005, Pages 107-109 Noninvasive visualization of the coronary arteries with multi-slice computed tomography; influence of heart rate on diagnostic accuracy. Henneman MM, Bax JJ, Schuijf JD, van der Wall EE
Cited 48 times since 2005 (2.6 per year) source: EuropePMC
Human molecular genetics, Volume 15, Issue 2, 1 1 2005, Pages 213-221 Human mesenchymal stem cells ectopically expressing full-length dystrophin can complement Duchenne muscular dystrophy myotubes by cell fusion. Gonçalves MA, de Vries AA, Holkers M, van de Watering MJ, van der Velde I, van Nierop GP, Valerio D, Knaän-Shanzer S
Duchenne muscular dystrophy (DMD) is the most prevalent inheritable muscle disease. It is caused by mutations in the approximately 2.5-megabase dystrophin (Dys) encoding gene. Therapeutic attempts at DMD have relied on injection of allogeneic Dys-positive myoblasts. The immune rejection of these cells and their limited availability have prompted the search for alternative therapies and sources of myogenic cells. Stem cell-based gene therapy aims to restore tissue function by the transplantation... Abstract
Cited 25 times since 2005 (1.4 per year) source: EuropePMC
Heart rhythm, Volume 2, Issue 12, 1 1 2005, Pages 1286-1293 Dispersion of repolarization in cardiac resynchronization therapy. van Huysduynen BH, Swenne CA, Bax JJ, Bleeker GB, Draisma HH, van Erven L, Molhoek SG, van de Vooren H, van der Wall EE, Schalij MJ
Background: Proarrhythmic effects of cardiac resynchronization therapy (CRT) as a result of increased transmural dispersion of repolarization (TDR) induced by left ventricular (LV) epicardial pacing in a subset of vulnerable patients have been reported. The possibility of identifying these patients by ECG repolarization indices has been suggested. Objectives: The purpose of this study was to test whether repolarization indices on the ECG can be used to measure dispersion of repolarization during... Abstract
Cited 7 times since 2005 (0.4 per year) source: EuropePMC
The American journal of medicine, Volume 118, Issue 12, 1 1 2005, Pages 1381-1386 Pacemaker stress echocardiography predicts cardiac events in patients with permanent pacemaker. Biagini E, Schinkel AF, Elhendy A, Bax JJ, Rizzello V, van Domburg RT, Krenning BJ, Schouten O, Branzi A, Rocchi G, Simoons ML, Poldermans D
Purpose: Noninvasive pacemaker stress echocardiography is a newly introduced method for the diagnosis of coronary artery disease in patients with a permanent pacemaker. The prognostic value of pacemaker stress echocardiography has not been studied. Subjects and methods: We studied 136 patients (mean age 64+/-12 years) with a permanent pacemaker who underwent pacemaker stress echocardiography for evaluation of coronary artery disease. All patients underwent pacemaker stress echocardiography by ex... Abstract
Cited 176 times since 2005 (9.5 per year) source: EuropePMC
The Journal of investigative dermatology, Volume 125, Issue 6, 1 1 2005, Pages 1163-1173 High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis. de Jongh GJ, Zeeuwen PL, Kucharekova M, Pfundt R, van der Valk PG, Blokx W, Dogan A, Hiemstra PS, van de Kerkhof PC, Schalkwijk J
Recently, it was shown that lesional skin of atopic dermatitis patients expresses low levels of some antimicrobial peptides, compared with psoriasis patients. Here we performed microarray analysis on mRNA from purified lesional epidermal cells of patients with chronic plaque psoriasis and chronic atopic dermatitis, to investigate whether this is a general phenomenon for host defense proteins, and how specific it is for this class of molecules. Microarray data were confirmed on a selected set of... Abstract
Cited 14 times since 2005 (0.8 per year) source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 46, Issue 12, 1 1 2005, Pages 2003-2008 Risk stratification of patients with angina pectoris by stress 99mTc-tetrofosmin myocardial perfusion imaging. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Huurman A, Feringa HH, Poldermans D
Unlabelled: Angina pectoris is a major symptom associated with myocardial ischemia. The aim of this study was to find whether stress myocardial perfusion imaging can independently predict mortality in patients with angina. Methods: We studied 455 patients with stable angina pectoris by exercise or dobutamine stress (99m)Tc-tetrofosmin myocardial perfusion tomographic imaging. An abnormal finding was defined as a reversible or fixed perfusion abnormality. The endpoint during follow-up was death f... Abstract
Cited 27 times since 2005 (1.5 per year) source: EuropePMC
Chest, Volume 128, Issue 6 Suppl, 1 1 2005, Pages 628S-630S Interventricular mechanical asynchrony due to right ventricular pressure overload in pulmonary hypertension plays an important role in impaired left ventricular filling. Vonk-Noordegraaf A, Marcus JT, Gan CT, Boonstra A, Postmus PE
The Annals of thoracic surgery, Volume 80, Issue 6, 1 1 2005, Pages 2255-2256 Invited commentary. Braun J
Cited 58 times since 2005 (3.1 per year) source: EuropePMC
Investigative radiology, Volume 40, Issue 12, 1 1 2005, Pages 777-783 Variability in densitometric assessment of pulmonary emphysema with computed tomography. Bakker ME, Stolk J, Putter H, Shaker SB, Parr DG, Piitulainen E, Russi EW, Dirksen A, Stockley RA, Reiber JH, Stoel BC
Objectives: The objectives of this study were to investigate whether computed tomography (CT) densitometry can be applied consistently in different centers; and to evaluate the reproducibility of densitometric quantification of emphysema by assessment of different sources of variation, ie, intersite, interscan and inter- and intraobserver variability, in comparison with intersubject variability. Materials and methods: In 5 different hospitals, 119 patients with emphysema were scanned using stand... Abstract