Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7490 results
Cited 46 times since 2006 (2.6 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 13, Issue 4, 1 1 2006, Pages 480-487 Assessment of global and regional left ventricular function and volumes with 64-slice MSCT: a comparison with 2D echocardiography. Henneman MM, Schuijf JD, Jukema JW, Holman ER, Lamb HJ, de Roos A, van der Wall EE, Bax JJ
Background: In patients with coronary artery disease (CAD), LV function and volumes are important parameters for long-term prognosis. Multislice computed tomography (MSCT) allows noninvasive assessment of the coronary arteries, but the accuracy of 64-slice MSCT for the assessment of left ventricular (LV) volumes and function is unknown. Methods and results: A head-to-head comparison between 64-slice MSCT and 2-dimensional (2D) echocardiography was performed in 40 patients with known or suspected... Abstract
Cited 5 times since 2006 (0.3 per year) source: EuropePMC
The American journal of cardiology, Volume 98, Issue 5, 30 5 2006, Pages 585-590 Prognostic value of exercise stress technetium-99m-tetrofosmin myocardial perfusion imaging in patients with normal baseline electrocardiograms. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Huurman A, Feringa HH, Poldermans D
Exercise stress electrocardiography is the recommended method for cardiac evaluation of patients with normal electrocardiograms (ECGs). There are no data to indicate an independent value of myocardial perfusion imaging (MPI) in predicting mortality in these patients. This study assessed the value of exercise stress MPI in predicting mortality in patients with normal baseline ECGs. We studied 319 patients (55 +/- 10 years of age; 180 men) with normal ECGs by exercise stress technetium-99m tetrofo... Abstract
Cited 1 times since 2006 (0.1 per year) source: EuropePMC
Medical science monitor : international medical journal of experimental and clinical research, Volume 12, Issue 7, 28 4 2006, Pages CR308-14 Long-term follow-up of mitral valve repair: a single-center experience. Shahin GM, van der Heijden GJ, Kelder JC, Boulaksil M, Knaepen PJ, Six AJ
Background: Our aim was to conduct a long-term follow-up of patients after mitral valve repair for incompetence. We identified determinants for mortality and compared mortality with standardized mortality rates of the Dutch population. Material/methods: We included in this single-center retrospective study 119 patients operated from March 1976 to February 1981. Patients with previous mitral valve surgery, isolated mitral stenosis, and congenital heart disease were excluded. Routine echocardiogra... Abstract
Cited 44 times since 2006 (2.5 per year) source: EuropePMC
Heart rhythm, Volume 3, Issue 9, 15 3 2006, Pages 1092-1099 Elucidation of the spatial ventricular gradient and its link with dispersion of repolarization. Draisma HH, Schalij MJ, van der Wall EE, Swenne CA
The ventricular gradient, a notion conceived by Wilson et al during the 1930s, has contributed considerably to a better understanding of the ECG manifestations of the cardiac repolarization process. The power of the ventricular gradient is its ability to assess the primary factors that contribute to the T wave (i.e., heterogeneity of action potential morphology throughout the ventricles) in the presence of secondary factors contributing to the T wave (i.e., heterogeneity in ventricular depolariz... Abstract
Cited 178 times since 2006 (9.9 per year) source: EuropePMC
Microbes and infection, Volume 8, Issue 8, 13 2 2006, Pages 2052-2060 Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis. Leyten EM, Lin MY, Franken KL, Friggen AH, Prins C, van Meijgaarden KE, Voskuil MI, Weldingh K, Andersen P, Schoolnik GK, Arend SM, Ottenhoff TH, Klein MR
The dormancy (DosR) regulon of Mycobacterium tuberculosis is expressed in vitro during hypoxia and low-dose nitric oxide stimulation. Tubercle bacilli are thought to encounter these conditions in humans during latent infection. In this study, immune responses were evaluated to 25 most strongly induced DosR-regulon-encoded proteins, referred to as latency antigens. Proliferation assays were performed using M. tuberculosis-specific T-cell lines and peripheral blood mononuclear cells (PBMC) from tu... Abstract
Cited 10 times since 2006 (0.6 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 33, Issue 10, 9 2 2006, Pages 1157-1161 Prognostic value of stress 99mTc-tetrofosmin myocardial perfusion imaging in predicting all-cause mortality: a 6-year follow-up study. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Biagini E, Poldermans D
Purpose: The aim of this study was to ascertain whether stress myocardial perfusion imaging can independently predict long-term mortality. Methods: We studied 1,386 patients with known or suspected coronary artery disease by means of stress 99mTc-tetrofosmin myocardial perfusion tomography. The end point during follow-up was death from any cause. Mortality rates were compared with that in a reference population using calculated age- and gender-specific data in the general population. Results: Me... Abstract
Cited 8 times since 2006 (0.4 per year) source: EuropePMC
The American journal of cardiology, Volume 98, Issue 3, 6 1 2006, Pages 309-313 Role of calcified spots detected by intravascular ultrasound in patients with ST-segment elevation acute myocardial infarction. van der Hoeven BL, Liem SS, Oemrawsingh PV, Dijkstra J, Jukema JW, Putter H, Atsma DE, van der Wall EE, Bax JJ, Reiber JC, Schalij MJ
Electron beam computed tomographic studies have demonstrated that the extent of intracoronary calcium is related to risk of coronary events. This study was performed to gain further insight into the distribution of focal calcifications and their relation to the site of plaque rupture within the culprit artery in consecutive patients (n = 60) with acute myocardial infarction (AMI) using intravascular ultrasound imaging. Calcifications in the culprit lesion and adjacent segments were classified an... Abstract
Cited 566 times since 2006 (31.6 per year) source: EuropePMC
Circulation, Volume 113, Issue 23, 5 1 2006, Pages 2744-2753 Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJ, Krams R, de Crom R
Background: Atherosclerotic lesions are predominantly observed in curved arteries and near side branches, where low or oscillatory shear stress patterns occur, suggesting a causal connection. However, the effect of shear stress on plaque vulnerability is unknown because the lack of an appropriate in vivo model precludes cause-effect studies. Methods and results: We developed a perivascular shear stress modifier that induces regions of lowered, increased, and lowered/oscillatory (ie, with vortice... Abstract
Cited 10 times since 2006 (0.6 per year) source: EuropePMC
The American journal of cardiology, Volume 98, Issue 2, 5 1 2006, Pages 262-266 Pregnancy after biventricular repair for pulmonary atresia with ventricular septal defect. Drenthen W, Pieper PG, Zoon N, Roos-Hesselink JW, Voors AA, Mulder BJ, van Dijk AP, Sollie KM, Vliegen HW, Ebels T, van Veldhuisen DJ, ZAHARA Investigators
Information on pregnancy and delivery in women with biventricular repair for isolated noncomplex pulmonary atresia with a ventricular septal defect (PAVSD) is limited. Using a nationwide congenital heart disease registry (CONgenital CORvitia [CONCOR]), 9 women with biventricular repair for PAVSD (aged 21 to 38 years) were identified. Ten pregnancies were observed in 5 different women with PAVSD, including 3 spontaneous miscarriages. Clinically significant (non)cardiac complications were document... Abstract
Cited 4 times since 2006 (0.2 per year) source: EuropePMC
The American journal of cardiology, Volume 98, Issue 2, 5 1 2006, Pages 259-261 Fertility, pregnancy, and delivery after biventricular repair for pulmonary atresia with an intact ventricular septum. Drenthen W, Pieper PG, Roos-Hesselink JW, Zoon N, Voors AA, Mulder BJ, van Dijk AP, Vliegen HW, Sollie KM, Ebels T, van Veldhuisen DJ, ZAHARA Investigators
The objective of the present study to investigate fertility, pregnancy, and delivery in women with biventricular repair for pulmonary atresia with an intact ventricular septum (PAIVS). Using a nationwide registry (CONCOR), 37 patients with pulmonary atresia were identified, 6 of whom (aged 21 to 34 years) had biventricular repair for PAIVS. Three PAIVS patients had a total of 5 pregnancies, including 1 abortion and 1 ectopic pregnancy. Besides minor noncardiac complications, the 3 live-birth pre... Abstract
Cited 47 times since 2006 (2.6 per year) source: EuropePMC
Molecular immunology, Volume 44, Issue 5, 5 1 2006, Pages 803-811 Epithelial differentiation is a determinant in the production of eotaxin-2 and -3 by bronchial epithelial cells in response to IL-4 and IL-13. van Wetering S, Zuyderduyn S, Ninaber DK, van Sterkenburg MA, Rabe KF, Hiemstra PS
The composition of the airway epithelium is dynamic and epithelial differentiation is regulated by endogenous mediators as well as inhaled substances. In atopic asthma the differentiation of the epithelium is altered. Various studies have addressed the ability of cultured airway epithelial cells to release the eosinophil-attractant chemokines eotaxin, eotaxin-2 and eotaxin-3 using epithelial cell lines or poorly differentiated primary cells. Since little is known about the role of the epithelial... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 14, Issue 6, 1 1 2006, Pages 207-208 Pulmonary arterial hypertension associated with congenital heart disease: the efficacy of drug treatment in symptomatic patients. Henkens IR, Vliegen HW
Cited 22 times since 2006 (1.2 per year) source: EuropePMC
Acta cardiologica, Volume 61, Issue 3, 1 1 2006, Pages 327-331 Apolipoprotein-E polymorphism and response to pravastatin in men with coronary artery disease (REGRESS). Maitland-van der Zee AH, Jukema JW, Zwinderman AH, Hallman DM, De Boer A, Kastelein JJ, De Knijff P
Objective: [corrected] The influence ofApoE polymorphism on the efficacy of statins in lowering plasma lipids and lipoproteins and improving angiographic parameters was assessed. Methods: ApoE genotypes were studied in a group (n = 815) of well-characterised male coronary artery disease (CAD) patients who participated in the lipid-lowering regression study 'Regression Growth Evaluation Statin Study (REGRESS)'. Results: There was a significant interaction between treatment (placebo/prav... Abstract
Cited 20 times since 2006 (1.1 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 17, Issue 6, 1 1 2006, Pages 586-593 Serial reevaluation for ARVD/C is indicated in patients presenting with left bundle branch block ventricular tachycardia and minor ECG abnormalities. Kiès P, Bootsma M, Bax JJ, Zeppenfeld K, van Erven L, Wijffels MC, van der Wall EE, Schalij MJ
Introduction: Diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is based on a set of criteria proposed by the International Task Force (TF) for Cardiomyopathies in 1994. To fulfill these criteria, presence of both electrocardiographic and anatomical abnormalities must be assessed with ECG and imaging techniques, respectively. This may be difficult in patients with early/mild forms of the disease as detectable structural abnormalities may still be absent. We evaluate... Abstract
Cited 14 times since 2006 (0.8 per year) source: EuropePMC
Current drug discovery technologies, Volume 3, Issue 2, 1 1 2006, Pages 135-144 Selective targeting of liposomes to macrophages using a ligand with high affinity for the macrophage scavenger receptor class A. Rensen PC, Gras JC, Lindfors EK, van Dijk KW, Jukema JW, van Berkel TJ, Biessen EA
Macrophages play an important role in inflammatory processes and are crucially involved in the onset and progression of atherosclerosis and tumorigenesis. Therefore, macrophages are regarded as an excellent target for therapeutic intervention. Since the scavenger receptor class A (SRA) is highly expressed on macrophages, we developed in the present study an SRA-specific particulate drug carrier by providing phosphatidylcholine liposomes with a targeting ligand for SRA. To enable firm association... Abstract
Cited 34 times since 2006 (1.9 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 92, Issue 12, 1 1 2006, Pages 1779-1783 Comprehensive cardiac assessment with multislice computed tomography: evaluation of left ventricular function and perfusion in addition to coronary anatomy in patients with previous myocardial infarction. Henneman MM, Schuijf JD, Jukema JW, Lamb HJ, de Roos A, Dibbets P, Stokkel MP, van der Wall EE, Bax JJ
Objective: To evaluate a comprehensive multislice computed tomography (MSCT) protocol in patients with previous infarction, including assessment of coronary artery stenoses, left ventricular (LV) function and perfusion. Patients and methods: 16-slice MSCT was performed in 21 patients with previous infarction; from the MSCT data, coronary artery stenoses, (regional and global) LV function and perfusion were assessed. Invasive coronary angiography and gated single-photon emission computed tomograp... Abstract
Cited 7 times since 2006 (0.4 per year) source: EuropePMC
Current drug targets, Volume 7, Issue 6, 1 1 2006, Pages 743-750 Antimicrobial peptides in COPD--basic biology and therapeutic applications. Bals R, Hiemstra PS
A large number of studies have implicated activation of innate immune mechanisms in the pathogenesis of chronic obstructive pulmonary disease (COPD). Accumulation of inflammatory cells, chemokines and pro-inflammatory cytokines is a hallmark of activation of these mechanisms, but only a few studies have focussed on antimicrobial peptides in COPD. These peptides are a central component of innate immunity, and airway epithelial cells and neutrophils in the lung are the main cellular sources. In ad... Abstract
Cited 22 times since 2006 (1.2 per year) source: EuropePMC
American heart journal, Volume 151, Issue 6, 1 1 2006, Pages 1323.e7-12 The impact of hypertension on systolic and diastolic left ventricular function. A tissue Doppler echocardiographic study. Bountioukos M, Schinkel AF, Bax JJ, Lampropoulos S, Poldermans D
Background: The purpose of this study is to assess the impact of hypertension on systolic function and diastolic function using 2-dimensional echocardiography, conventional Doppler imaging of the transmitral inflow, and tissue Doppler imaging (TDI) of the mitral annulus. Methods: From an outpatient clinic population, 414 consecutive patients underwent 2-dimensional echocardiography, conventional Doppler imaging of the transmitral inflow, and TDI of the septal, lateral, inferior, and posterior wa... Abstract
Cited 12 times since 2006 (0.7 per year) source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 1, Issue 5, 1 1 2006, Pages 497-498 The Liverpool Statement 2005: priorities for the European Union/United States spiral computed tomography collaborative group. Field JK, Smith RA, Duffy SW, Berg CD, van Klaveren R, Henschke CI, Carbone D, Postmus PE, Paci E, Hirsch FR, Mulshine JL
The Liverpool Statement 2005 was developed at the Fourth International Lung Cancer Molecular Biomarkers Workshop in Liverpool (October 27-29, 2005) and focused on the priorities for the European Union/United States (EU-US) Spiral Computed Tomography (CT) Collaborative Group. The application of spiral CT technology for early lung cancer screening has gained enormous momentum in the past 5 years. The EU-US Spiral CT Collaboration was initiated in 2001 in Liverpool, and subsequent meetings througho... Abstract
Nature clinical practice. Cardiovascular medicine, Volume 3, Issue 6, 1 1 2006, Pages 304-305 Can dobutamine stress echocardiography predict patient outcome after acute myocardial infarction? Bax JJ, Poldermans D