Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7496 results
Cited 56 times since 2007 (3.4 per year) source: EuropePMC
American heart journal, Volume 154, Issue 6, 14 2 2007, Pages 1160-1165 Myocardial contractile reserve predicts improvement in left ventricular function after cardiac resynchronization therapy. Ypenburg C, Sieders A, Bleeker GB, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Background: Myocardial contractile reserve has been shown to provide important prognostic information in patients with heart failure. We hypothesized that myocardial contractile reserve would predict left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). Methods: Thirty-one consecutive patients with heart failure (LV ejection fraction [LVEF] 26% +/- 7%, 35% nonischemic cardiomyopathy) underwent echocardiography during low-dose dobutamine infusion before CRT impla... Abstract
Cited 48 times since 2007 (2.9 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 35, Issue 1, 12 2 2007, Pages 166-173 Left ventricular dyssynchrony assessed by two three-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging. Marsan NA, Henneman MM, Chen J, Ypenburg C, Dibbets P, Ghio S, Bleeker GB, Stokkel MP, van der Wall EE, Tavazzi L, Garcia EV, Bax JJ
Purpose: To compare left ventricular (LV) dyssynchrony assessment by phase analysis from gated myocardial perfusion SPECT (GMPS) with LV dyssynchrony assessment by tri-plane tissue Doppler imaging (TDI). Baseline LV dyssynchrony assessed with standard deviation (SD) of time-to-peak systolic velocity of 12 LV segments (Ts-SD) with TDI has proven to be a powerful predictor of response to CRT. Information on LV dyssynchrony can also be provided by GMPS with phase analysis of regional LV maximal cou... Abstract
Cited 9 times since 2007 (0.5 per year) source: EuropePMC
European journal of cancer (Oxford, England : 1990), Volume 43, Issue 16, 10 2 2007, Pages 2345-2350 Phase III study of cyclophosphamide, doxorubicin, and etoposide compared with carboplatin and paclitaxel in patients with extensive disease small-cell lung cancer. de Jong WK, Groen HJ, Koolen MG, Biesma B, Willems LN, Kwa HB, van Bochove A, van Tinteren H, Smit EF
The progression-free survival (PFS) of cyclophosphamide/doxorubicin/etoposide (CDE) and carboplatin/paclitaxel (CP) was compared in chemonaive patients with extensive disease small-cell lung cancer (ED-SCLC). A total of 203 patients were randomised to three-weekly CDE (n=102) or CP (n=101) for five cycles. Tumour response rates in CDE and CP were 60% and 61%. PFS of CP was 5.2 months, PFS of CDE 4.9 months (p=0.60). The major difference in toxicity between CDE and CP was grade 4 leukocytopaenia... Abstract
Cited 11 times since 2007 (0.7 per year) source: EuropePMC
American journal of physiology. Lung cellular and molecular physiology, Volume 293, Issue 5, 7 1 2007, Pages L1321-31 Microtubule dynamics and Rac-1 signaling independently regulate barrier function in lung epithelial cells. Lorenowicz MJ, Fernandez-Borja M, van Stalborch AM, van Sterkenburg MA, Hiemstra PS, Hordijk PL
Cadherin-mediated cell-cell adhesion controls the morphology and function of epithelial cells and is a critical component of the pathology of chronic inflammatory disorders. Dynamic interactions between cadherins and the actin cytoskeleton are required for stable cell-cell contact. Besides actin, microtubules also target intercellular, cadherin-based junctions and contribute to their formation and stability. Here, we studied the role of microtubules in conjunction with Rho-like GTPases in the re... Abstract
Cited 35 times since 2007 (2.1 per year) source: EuropePMC
The European respiratory journal, Volume 31, Issue 1, 5 1 2007, Pages 70-77 Chronic bronchitis sub-phenotype within COPD: inflammation in sputum and biopsies. Snoeck-Stroband JB, Lapperre TS, Gosman MM, Boezen HM, Timens W, ten Hacken NH, Sont JK, Sterk PJ, Hiemstra PS, Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease (GLUCOLD) Study Group
The presence of chronic bronchitis predicts a more rapid decline of forced expiratory volume in one second (FEV(1)) in patients with chronic obstructive pulmonary disease (COPD). The hallmark of COPD is airway inflammation. It was hypothesised that COPD patients with chronic bronchitis are characterised by a distinct inflammatory cell profile, as measured in bronchial biopsies and sputum. From 114 COPD patients (male/female ratio 99/15, mean+/-sd age 62+/-8 yrs, current smoking 63%, post-broncho... Abstract
Cited 104 times since 2007 (6.2 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 50, Issue 12, 4 1 2007, Pages 1180-1188 Speckle-tracking radial strain reveals left ventricular dyssynchrony in patients with permanent right ventricular pacing. Tops LF, Suffoletto MS, Bleeker GB, Boersma E, van der Wall EE, Gorcsan J, Schalij MJ, Bax JJ
Objectives: Speckle-tracking strain analysis was used to assess the effects of permanent right ventricular (RV) pacing on the heterogeneity in timing of regional wall strain and left ventricular (LV) dyssynchrony. Background: Recent studies have shown detrimental effects of RV pacing, possibly related to the induction of LV dyssynchrony. Methods: Fifty-eight patients treated with His bundle ablation and pacemaker implantation were studied. To assess the effect of RV pacing on time-to-peak radial... Abstract
Cited 137 times since 2007 (8.2 per year) source: EuropePMC
Circulation, Volume 116, Issue 13, 4 1 2007, Pages 1440-1448 Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: analysis in patients with echocardiographic evidence of left ventricular dyssynchrony at baseline. Bleeker GB, Mollema SA, Holman ER, Van de Veire N, Ypenburg C, Boersma E, van der Wall EE, Schalij MJ, Bax JJ
Background: Recent studies have demonstrated that a positive response to cardiac resynchronization therapy (CRT) is related to the presence of preimplantation left ventricular (LV) dyssynchrony. The time course and the extent of LV resynchronization after CRT implantation and their relationship to response are currently unknown. Methods and results: One hundred consecutive patients scheduled for implantation of a CRT device were prospectively included if they met the following criteria: New York... Abstract
Cited 7 times since 2007 (0.4 per year) source: EuropePMC
Journal of child neurology, Volume 22, Issue 9, 1 1 2007, Pages 1143-1146 Devic's neuromyelitis optica in an infant case. Yuksel D, Senbil N, Yilmaz D, Yavuz Gurer YK
Devic's neuromyelitis optica was orginally described as an acute severe monophasic syndrome characterised by myelitis and optic neuritis. The mean age at onset was reported to be around 40 years, with a wide range. However, Devic's neuromyelitis optica has also been seen in children. Prognosis of the syndrome was poor, and no satisfactory treatment was known. This article reports a 23-month-old boy with acute myelitis and optic neuritis who was diagnosed with Devic's neuromyelitis... Abstract
Cited 13 times since 2007 (0.8 per year) source: EuropePMC
Human gene therapy, Volume 18, Issue 9, 1 1 2007, Pages 861-869 Prolonged in vivo gene silencing by electroporation-mediated plasmid delivery of small interfering RNA. Eefting D, Grimbergen JM, de Vries MR, van Weel V, Kaijzel EL, Que I, Moon RT, Löwik CW, van Bockel JH, Quax PH
For the successful application of RNA interference in vivo, it is desired to achieve (local) delivery of small interfering RNAs (siRNAs) and long-term gene silencing. Nonviral electrodelivery is suitable to obtain local and prolonged expression of transgenes. By intramuscular electrodelivery of a plasmid in which two opposing human polymerase III promoters (H1 and U6) drive the expression of siRNA constructs that form functional double-stranded siRNAs, in combination with in vivo bioluminescence... Abstract
Cited 14 times since 2007 (0.8 per year) source: EuropePMC
Journal of pediatric surgery, Volume 42, Issue 9, 1 1 2007, Pages E23-5 Anorectal impalement in a pediatric patient with transanal evisceration of small bowel. Bronkhorst MW, Wilde JC, Hamming JF, Heij HA
Rectal injuries in the pediatric population are most often attributed to accidental falls on offending objects, sexual abuse, or blunt trauma. Anorectal impalement is a rare injury, and as a result, specific knowledge or experience on the treatment of this type of injury in children is sparse. The extent of injury is often difficult to assess. Mostly, therapeutical decisions are based on general knowledge in adults. We present a case of accidental anorectal impalement in a child by a fall on the... Abstract
Cited 14 times since 2007 (0.8 per year) source: EuropePMC
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, Volume 30, Issue 3, 1 1 2007, Pages 325-331 Systolic and diastolic ventricular function in the normal and extra-embryonic venous clipped chicken embryo of stage 24: a pressure-volume loop assessment. Stekelenburg-de Vos S, Steendijk P, Ursem NT, Wladimiroff JW, Poelmann RE
Objectives: Fluid mechanical forces affect cardiac development. In the chicken embryo, permanent obstruction of the right lateral vitelline vein by clipping reduces the mechanical load on the embryonic myocardium, which has been shown to induce a spectrum of outflow tract anomalies. Insight into the effects of this intervention on the mechanical function of the developing myocardium could contribute to a better understanding of the relationship between hemodynamics and cardiac morphogenesis. We... Abstract
Cited 3 times since 2007 (0.2 per year) source: EuropePMC
Coronary artery disease, Volume 18, Issue 6, 1 1 2007, Pages 483-487 Carotid artery stenting versus endarterectomy in relation to perioperative myocardial ischemia, troponin T release and major cardiac events. Feringa HH, Hendriks JM, Karagiannis S, Schouten O, Vidakovic R, van Sambeek MR, Klein J, Noordzij P, Bax JJ, Poldermans D
Background: Carotid artery stenting (CAS) is less invasive than endarterectomy. This study examined differences in perioperative myocardial ischemia, troponin T release and clinical cardiac events in patients undergoing CAS compared with endarterectomy. Methods: In an observational study, CAS was performed in 24 and carotid endarterectomy in 44 patients. Before surgery, clinical risk factors were noted and dobutamine stress echocardiography was performed for cardiac risk assessment. Perioperativ... Abstract
Journal of oncology practice, Volume 3, Issue 5, 1 1 2007, Pages 242-247 Influence of introduction of positron emission tomography on adherence to mediastinal staging protocols and performance of mediastinoscopy. Goosens M, Smulders SA, Smeenk FW, Daniëls-Gooszen AW, Donkers-van Rossum AB, Edelbroek MA, Huysmans DA, Michels AJ, van Straten BA, Postmus PE
Purpose: In this study, we investigated the impact of implementation of [(18)F] fluorodeoxyglucose positron emission tomography (FDG-PET) in daily practice on adherence to mediastinal staging protocols and performance of mediastinoscopy in non-small-cell lung cancer (NSCLC) patients who are possible candidates for surgical resection. Institutional review board approval was obtained. Patients and methods: From a nonuniversity teaching hospital and three surrounding community hospitals in Eindhove... Abstract
Nederlands tijdschrift voor geneeskunde, Volume 151, Issue 37, 1 1 2007, Pages 2055-2060 [Two patients with a rare manifestation of amyloidosis in the respiratory system]. Jacobs W, Vonk Noordegraaf A, Sutedja TG, Grünberg K, Postmus PE
Amyloidosis of the respiratory tract was diagnosed in 2 patients. The patients were men, 62 and 55 years ofage. The first patient presented with dyspnoea and diffuse parenchymal lung abnormalities. There was a rapidly progressive obstructive lung function disorder and a severe diffusion impairment. The second patient had haemoptysis due to tracheobronchial amyloidosis. Amyloidosis of the respiratory system is rarely diagnosed. Nearly all cases ofclinically relevant respiratory amyloidosis are du... Abstract
Cited 3 times since 2007 (0.2 per year) source: EuropePMC
Chest, Volume 132, Issue 3, 1 1 2007, Pages 1088-1092 A 31-year-old man with hemoptysis at high altitude and abnormal hepatic biochemistry tests. Bogaard HJ, Grotjohan HP, Tjwa E, van den Berg FG, Postmus PE, van Nieuwkerk CM, Vonk-Noordegraaf A
Cited 9 times since 2007 (0.5 per year) source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 2, Issue 9, 1 1 2007, Pages 813-818 A web site on lung cancer: who are the users and what are they looking for? Linssen C, Schook RM, The AM, Lammers E, Festen J, Postmus PE
Purpose: The Dutch Lung Cancer Information Centre launched the Web site www.longkanker.info in November 2003. The purpose of this article is to describe the launching of the Web site, its development, the type of visitors to the Web site, what they were looking for, and whether they found what they requested. Methods: Supervised by a panel (pulmonologists, patients, communication specialists), a large amount of material about lung cancer has been collected and edited into accessible language by... Abstract
Cited 25 times since 2007 (1.5 per year) source: EuropePMC
Current medical research and opinion, Volume 23, Issue 9, 1 1 2007, Pages 2235-2240 Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol. Bergheanu SC, Van Tol A, Dallinga-Thie GM, Liem A, Dunselman PH, Van der Bom JG, Jukema JW
Objective: Paraoxonase-1 (PON-1) is a high-density lipoprotein (HDL) associated enzyme involved in the protective mechanisms of HDL. Our aim was to compare the effect of treatment with rosuvastatin and atorvastatin on serum PON-1 activity. Methods: We performed a prespecified prospective study in 68 patients, part of a larger, multicentre randomized study--RADAR (Rosuvastatin and Atorvastatin in different Dosages And Reverse cholesterol transport). Patients aged 40-80 years, all men, with establ... Abstract
Cited 9 times since 2007 (0.5 per year) source: EuropePMC
Journal of vascular surgery, Volume 46, Issue 4, 30 5 2007, Pages 773-779 Assessment of three-dimensional stent-graft dynamics by using fluoroscopic roentgenographic stereophotogrammetric analysis. Koning OH, Kaptein BL, Garling EH, Hinnen JW, Hamming JF, Valstar ER, van Bockel JH
Objective: To validate the use of fluoroscopic roentgenographic stereophotogrammetric analysis (FRSA) for its feasibility and accuracy for measuring the three-dimensional dynamic motion of stent grafts. Methods: A digital biplane fluoroscopy setup was calibrated (Siemens Axiom Artis dBc). Stereo images were acquired of a static aortic model with a stent graft in different axial positions, imposed by a micromanipulator. The three-dimensional measurement error of FRSA was determined by comparing F... Abstract
Cited 35 times since 2007 (2.1 per year) source: EuropePMC
European journal of heart failure, Volume 9, Issue 10, 28 4 2007, Pages 1058-1063 Reverse ventricular remodelling after cardiac resynchronization therapy is associated with a reduction in serum tenascin-C and plasma matrix metalloproteinase-9 levels. Hessel MH, Bleeker GB, Bax JJ, Henneman MM, den Adel B, Klok M, Schalij MJ, Atsma DE, van der Laarse A
Background: In heart failure patients, cardiac resynchronization therapy (CRT) leads to reverse ventricular remodelling. Aim: The aim of this study was to evaluate whether changes in levels of circulating biomarkers of extracellular matrix metabolism correlate with the response to CRT. Methods and results: Clinical parameters, left ventricular (LV) volumes, and circulating levels of tenascin-C (TNC), matrix metalloproteinase-2 (MMP-2), MMP-9, and amino-terminal propeptide of brain natriuretic pe... Abstract
Cited 25 times since 2007 (1.5 per year) source: EuropePMC
The American journal of cardiology, Volume 100, Issue 9, 27 4 2007, Pages 1479-1484 Comparison of the incidences of cardiac arrhythmias, myocardial ischemia, and cardiac events in patients treated with endovascular versus open surgical repair of abdominal aortic aneurysms. Feringa HH, Karagiannis S, Vidakovic R, Noordzij PG, Brugts JJ, Schouten O, van Sambeek MR, Bax JJ, Poldermans D
This study examines differences in cardiac arrhythmias, perioperative myocardial ischemia, troponin T release, and cardiovascular events between endovascular and open repair of abdominal aortic aneurysms (AAAs). Of 175 patients, 126 underwent open AAA repair and 49 underwent endovascular AAA repair. Continuous 12-lead electrocardiographic monitoring, starting 1 day before surgery and continuing through 2 days after surgery, was used for cardiac arrhythmia and myocardial ischemia detection. Tropo... Abstract