Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7490 results
Cited 1 times since 2009 (0.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 53, Issue 4, 1 1 2009, Pages 373-398 Highlights of the Year in JACC 2008. DeMaria AN, Ben-Yehuda O, Bax JJ, Feld GK, Greenberg BH, Lew WY, Lima JA, Maisel AS, Narayan SM, Sahn DJ, Tsimikas S
Cited 36 times since 2009 (2.3 per year) source: EuropePMC
Developmental dynamics : an official publication of the American Association of Anatomists, Volume 238, Issue 1, 1 1 2009, Pages 183-193 Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node. Mahtab EA, Vicente-Steijn R, Hahurij ND, Jongbloed MR, Wisse LJ, DeRuiter MC, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Gittenberger-de Groot AC
We investigated the role of podoplanin in development of the sinus venosus myocardium comprising the sinoatrial node, dorsal atrial wall, and primary atrial septum as well as the myocardium of the cardinal and pulmonary veins. We analyzed podoplanin wild-type and knockout mouse embryos between embryonic day 9.5-15.5 using immunohistochemical marker podoplanin; sinoatrial-node marker HCN4; myocardial markers MLC-2a, Nkx2.5, as well as Cx43; coelomic marker WT-1; and epithelial-to-mesenchymal tran... Abstract
Cited 7 times since 2008 (0.5 per year) source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 37, Issue 4, 31 5 2009, Pages 486-491 Implementation of endovenous laser ablation for varicose veins in a large community hospital: the first 400 procedures. van den Bremer J, Joosten PP, Hamming JF, Moll FL
Unlabelled: Endovenous laser ablation (ELA) has become a standard treatment of the incompetent great saphenous vein (GSV). Our prospective audit examines the implementation of this new method in a large community hospital with special attention to obstacles, technical results, pain scores, failures and our learning curve. Methods: Three hundred and twenty-three patients (403 limbs) with incompetence of the GSV underwent ELA. Patients were assessed by clinical examination and venous duplex ultras... Abstract
Cited 19 times since 2008 (1.2 per year) source: EuropePMC
International journal of cardiology, Volume 134, Issue 3, 30 5 2009, Pages 302-312 Pulmonary vein and atrial wall pathology in human total anomalous pulmonary venous connection. Douglas YL, Jongbloed MR, den Hartog WC, Bartelings MM, Bogers AJ, Ebels T, DeRuiter MC, Gittenberger-de Groot AC
Background: Normally, the inside of the left atrial (LA) body and pulmonary veins (PVs) is lined by vessel wall tissue covered by myocardium. In total anomalous pulmonary venous connection (TAPVC), no connection of the PVs with the LA body exists. These veins have an increased incidence of PV stenosis. We describe the consequences of the absent connection for the histopathology of the wall of the LA body and the PVs, and hypothesize on a mechanism predisposing to PV stenosis. Methods and results... Abstract
Cited 34 times since 2008 (2.2 per year) source: EuropePMC
The American journal of cardiology, Volume 103, Issue 5, 26 4 2008, Pages 690-694 Comparison of time course of response to cardiac resynchronization therapy in patients with ischemic versus nonischemic cardiomyopathy. Marsan NA, Bleeker GB, van Bommel RJ, Ypenburg C, Delgado V, Borleffs CJ, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
The time course of the effects of cardiac resynchronization therapy (CRT) on left ventricular (LV) systolic function and reverse remodeling is still unknown and was the subject of this study. In particular, whether the acute benefit of CRT translates in late response was explored. Furthermore, the time course of response was compared between ischemic and nonischemic patients. A total of 222 consecutive patients with heart failure (135 ischemic) scheduled for CRT were included. Standard echocardi... Abstract
Cited 26 times since 2008 (1.7 per year) source: EuropePMC
Biochimica et biophysica acta, Volume 1791, Issue 3, 25 4 2008, Pages 191-197 PXR agonism decreases plasma HDL levels in ApoE3-Leiden.CETP mice. de Haan W, de Vries-van der Weij J, Mol IM, Hoekstra M, Romijn JA, Jukema JW, Havekes LM, Princen HM, Rensen PC
Pregnane X receptor (PXR) agonism has been shown to affect multiple steps in both the synthesis and catabolism of HDL, but its integrated effect on HDL metabolism in vivo remains unclear. The aim of this study was to evaluate the net effect of PXR agonism on HDL metabolism in ApoE3-Leiden (E3L) and E3L.CETP mice, well-established models for human-like lipoprotein metabolism. Female mice were fed a diet with increasing amounts of the potent PXR agonist 5-pregnen-3beta-ol-20-one-16alpha-carbonitri... Abstract
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 37, Issue 3, 25 4 2008, Pages 371 Comment on "Clinical endpoints in peripheral endovascular revascularisation trials: a case for standardised definitions Eur J Vasc Endovasc Surg 2008;36:409-9". Breek JC, De Vries J, Hamming JF
Cited 17 times since 2008 (1.1 per year) source: EuropePMC
Patient education and counseling, Volume 76, Issue 1, 20 3 2008, Pages 132-137 Cognitive coping and goal adjustment in people with Peripheral Arterial Disease: relationships with depressive symptoms. Garnefski N, Grol M, Kraaij V, Hamming JF
Objective: The aim was to study relationships between cognitive coping strategies, goal adjustment processes (goal disengagement and re-engagement) and symptoms of depression in people with Peripheral Arterial Disease (PAD). Methods: The sample consisted of 88 patients with PAD. Strategies of cognitive coping, goal disengagement, goal re-engagement, and depression were measured by written questionnaires. The main statistical methods were Pearson correlations and Multiple Regression Analyses. Res... Abstract
Cardiovascular drugs and therapy, Volume 23, Issue 2, 19 3 2008, Pages 103-105 Early systemic inflammatory response to drug-eluting stents implantation: the heart of the difference? Editorial to: "Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation" by Li et al. Pires NM, Jukema JW
Cited 36 times since 2008 (2.3 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 29, Issue 2, 18 3 2008, Pages 188-194 Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis. de Nooijer R, Bot I, von der Thüsen JH, Leeuwenburgh MA, Overkleeft HS, Kraaijeveld AO, Dorland R, van Santbrink PJ, van Heiningen SH, Westra MM, Kovanen PT, Jukema JW, van der Wall EE, van Berkel TJ, Shi GP, Biessen EA
Objective: A dysbalance of proteases and their inhibitors is instrumental in remodeling of atherosclerotic plaques. One of the proteases implicated in matrix degradation is cathepsin-S (CatS). To address its role in advanced lesion composition, we generated chimeric LDLr(-/-) mice deficient in leukocyte CatS by transplantation with CatS(-/-)xLDLr(-/-) or with LDLr(-/-) bone marrow and administered a high-fat diet. Methods and results: No difference in aortic root lesion size could be detected be... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 20, Issue 5, 17 3 2008, Pages 536-538 Should the left ventricular pacing lead be positioned at the site of latest mechanical activation in cardiac resynchronization therapy? Van Bommel RJ, Schalij MJ, Bax JJ
Cited 36 times since 2008 (2.3 per year) source: EuropePMC
Heart rhythm, Volume 6, Issue 3, 13 2 2008, Pages 305-310 Clinical importance of new-onset atrial fibrillation after cardiac resynchronization therapy. Borleffs CJ, Ypenburg C, van Bommel RJ, Delgado V, van Erven L, Schalij MJ, Bax JJ
Background: Data on the occurrence and implications of new-onset atrial fibrillation (AF) following cardiac resynchronization therapy (CRT) are scarce. We studied the incidence of new onset AF in CRT-defibrillator (CRT-D) recipients. The influence of new-onset AF on echocardiographic response to CRT and the rate of adverse events also were evaluated. Objective: The purpose of this study was to assess the incidence and implications of new-onset AF following CRT. Methods: The study population cons... Abstract
Cited 53 times since 2008 (3.4 per year) source: EuropePMC
Allergy, Volume 64, Issue 1, 12 2 2008, Pages 72-80 Eosinophils in bronchial mucosa of asthmatics after allergen challenge: effect of anti-IgE treatment. van Rensen EL, Evertse CE, van Schadewijk WA, van Wijngaarden S, Ayre G, Mauad T, Hiemstra PS, Sterk PJ, Rabe KF
Background: Anti-IgE, omalizumab, inhibits the allergen response in patients with asthma. This has not been directly related to changes in inflammatory conditions. We hypothesized that anti-IgE exerts its effects by reducing airway inflammation. To that end, the effect of anti-IgE on allergen-induced inflammation in bronchial biopsies in 25 patients with asthma was investigated in a randomized, double-blind, placebo-controlled study. Methods: Allergen challenge followed by a bronchoscopy at 24 h... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 25, Issue 2, 5 1 2008, Pages 141-144 Atherosclerotic plaque imaging by PET/CT; can inactive, active and mixed plaques be discerned? van der Wall EE, Schuijf JD, Jukema JW, Bax JJ, van der Laarse A
Cited 2 times since 2008 (0.1 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 296, Issue 2, 5 1 2008, Pages H342-9 Cardiac phase-dependent time normalization reduces load dependence of time-varying elastance. Kind T, Westerhof N, Faes TJ, Lankhaar JW, Steendijk P, Vonk-Noordegraaf A
The time-varying elastance concept provides a comprehensive description of the intrinsic mechanical properties of the left ventricle that are assumed to be load independent. Based on pressure-volume measurements obtained with combined pressure conductance catheterization in six open-chest anesthetized sheep, we show that the time to reach end systole (defined as maximal elastance) is progressively prolonged for increasing ventricle pressures, which challenges the original (load-independent) time... Abstract
Cited 21 times since 2008 (1.4 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 36, Issue 4, 3 1 2008, Pages 594-601 Agreement and disagreement between contrast-enhanced magnetic resonance imaging and nuclear imaging for assessment of myocardial viability. Roes SD, Kaandorp TA, Marsan NA, Westenberg JJ, Dibbets-Schneider P, Stokkel MP, Lamb HJ, van der Wall EE, de Roos A, Bax JJ
Purpose: The purpose of this study was to compare contrast-enhanced MRI and nuclear imaging with (99m)Tc-tetrofosmin and (18)F-fluorodeoxyglucose ((18)F-FDG) single photon emission computed tomography (SPECT) for assessment of myocardial viability. Methods: Included in the study were 60 patients with severe ischaemic left ventricular (LV) dysfunction who underwent contrast-enhanced MRI, (99m)Tc-tetrofosmin and (18)F-FDG SPECT. Myocardial segments were assigned a wall motion score from 0 (normoki... Abstract
Cited 25 times since 2008 (1.6 per year) source: EuropePMC
British journal of cancer, Volume 100, Issue 1, 2 1 2008, Pages 145-152 Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients. Galleges Ruiz MI, Floor K, Steinberg SM, Grünberg K, Thunnissen FB, Belien JA, Meijer GA, Peters GJ, Smit EF, Rodriguez JA, Giaccone G
The purpose of this study is to evaluate the prognostic value of the combined assessment of multiple molecular markers related to the epidermal growth factor receptor (EGFR) pathway in resected non-small cell lung cancer (NSCLC) patients. Tumour specimens of 178 NSCLC patients were collected and analysed for EGFR and KRAS mutation status by DNA sequencing, and for EGFR copy number by fluorescent in situ hybridisation. Tissue microarrays were generated and used to determine the expression of mult... Abstract
Cited 18 times since 2008 (1.2 per year) source: EuropePMC
Proceedings of the American Thoracic Society, Volume 5, Issue 9, 1 1 2008, Pages 929-933 Quality control in longitudinal studies with computed tomographic densitometry of the lungs. Stoel BC, Bode F, Rames A, Soliman S, Reiber JH, Stolk J
To guarantee the reliability of densitometric data in clinical trials on pulmonary emphysema a quality control procedure is presented, to prevent that a measured progression in lung density could be reflected by a gradual change in the maintenance of the computed tomographic scanner. For that purpose, a foam phantom has been developed, which mimicks the densities of emphysematous lung tissue, fixed in a sealed Perspex box. Analysis software was developed to automatically compare the density read... Abstract
Cited 59 times since 2008 (3.8 per year) source: EuropePMC
Proceedings of the American Thoracic Society, Volume 5, Issue 9, 1 1 2008, Pages 919-924 Volume correction in computed tomography densitometry for follow-up studies on pulmonary emphysema. Stoel BC, Putter H, Bakker ME, Dirksen A, Stockley RA, Piitulainen E, Russi EW, Parr D, Shaker SB, Reiber JH, Stolk J
Lung densitometry in drug evaluation trials can be confounded by changes in inspiration levels between computed tomography (CT) scans, limiting its sensitivity to detect changes over time. Therefore our aim was to explore whether the sensitivity of lung densitometry could be improved by correcting the measurements for changes in lung volume, based on the estimated relation between density (as measured with the 15th percentile point) and lung volume. We compared four correction methods, using CT... Abstract
Cited 24 times since 2008 (1.6 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 31, Issue 12, 1 1 2008, Pages 1628-1639 Noninvasive imaging in cardiac resynchronization therapy--Part 2: Follow-up and optimization of settings. Ypenburg C, Van De Veire N, Westenberg JJ, Bleeker GB, Marsan NA, Henneman MM, Van Der Wall EE, Schalij MJ, Abraham TP, Barold SS, Bax JJ
Cardiac resynchronization therapy (CRT) has become a therapeutic option for drug-refractory heart failure. Several noninvasive imaging techniques play an increasingly important role before and after device implantation. This review highlights the acute and long-term CRT benefits after implantation as assessed with echocardiography and nuclear imaging. Furthermore, optimization of CRT settings, in particular atrioventricular and interventricular delay, will be discussed using echocardiography and... Abstract