Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7518 results
Cited 34 times since 2010 (2.5 per year) source: EuropePMC
Breast cancer research and treatment, Volume 128, Issue 3, 7 1 2010, Pages 679-689 Image-guided tumor resection using real-time near-infrared fluorescence in a syngeneic rat model of primary breast cancer. Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Que I, Dijkstra J, Kaijzel EL, Prins F, Löwik CW, Smit VT, van de Velde CJ, Vahrmeijer AL
Tumor involvement of resection margins is found in a large proportion of patients who undergo breast-conserving surgery. Near-infrared (NIR) fluorescence imaging is an experimental technique to visualize cancer cells during surgery. To determine the accuracy of real-time NIR fluorescence imaging in obtaining tumor-free resection margins, a protease-activatable NIR fluorescence probe and an intraoperative camera system were used in the EMR86 orthotopic syngeneic breast cancer rat model. Influence... Abstract
Cited 27 times since 2010 (2 per year) source: EuropePMC
Journal of applied physiology (Bethesda, Md. : 1985), Volume 109, Issue 6, 2 1 2010, Pages 1582-1591 Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease. Muskulus M, Slats AM, Sterk PJ, Verduyn-Lunel S
Asthma and COPD are chronic respiratory diseases that fluctuate widely with regard to clinical symptoms and airway obstruction, complicating treatment and prediction of exacerbations. Time series of respiratory impedance obtained by the forced oscillation technique are a convenient tool to study the respiratory system with high temporal resolution. In previous studies it was suggested that power-law-like fluctuations exist also in the healthy lung and that respiratory system impedance variabilit... Abstract
Cited 23 times since 2010 (1.7 per year) source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 5, Issue 9, 1 1 2010, Pages 1477-1480 Side-effects of long-term administration of erlotinib in patients with non-small cell lung cancer. Becker A, van Wijk A, Smit EF, Postmus PE
Introduction: Currently, the inhibitor of the epidermal growth factor receptor tyrosine kinase erlotinib is widely used for the treatment of non-small cell lung cancer. Patients with a mutation or deletion in the epidermal growth factor receptor gene will benefit most and are likely to receive the drug for long periods and willing to accept side effects if responding. Methods: Twenty-two cases with prolonged administration of erlotinib (at least 6 months) and side effects are reported. Three cas... Abstract
Cited 116 times since 2010 (8.5 per year) source: EuropePMC
Neurology, Volume 75, Issue 11, 1 1 2010, Pages 997-1002 Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up. van Elderen SG, de Roos A, de Craen AJ, Westendorp RG, Blauw GJ, Jukema JW, Bollen EL, Middelkoop HA, van Buchem MA, van der Grond J
Objective: To investigate progression of MRI-assessed manifestations of cerebral degeneration related to cognitive changes in a population of elderly patients with diabetes mellitus (DM) compared to age-matched control subjects. Methods: From a randomized controlled trial (PROSPER study), a study sample of 89 patients with DM and 438 control subjects without DM aged 70-82 years were included for brain MRI scanning and cognitive function testing at baseline and reexamination after 3 years. Change... Abstract
Cited 7 times since 2010 (0.5 per year) source: EuropePMC
Pharmacogenetics and genomics, Volume 20, Issue 9, 1 1 2010, Pages 544-552 Toll-like receptor 4 gene polymorphisms show no association with the risk of clinical or angiographic restenosis after percutaneous coronary intervention. Beijk MA, Boekholdt SM, Rittersma SZ, Pons D, Zwinderman AH, Doevendans PA, Tio RA, Tijssen JG, Jukema JW, de Winter RJ
Objective: Restenosis after percutaneous coronary intervention (PCI) remains an issue even in the drug-eluting stent era. Genetic polymorphisms may provide insight in the pathogenesis of restenosis and may help in the stratification of patients at risk for restenosis. The aim of this study was to examine whether polymorphisms at the toll-like receptor 4 (TLR4) locus, that are associated with impaired innate immune system and with an increased risk of cardiovascular events, were associated with c... Abstract
Cited 10 times since 2010 (0.7 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 18, Issue 9, 1 1 2010, Pages 408-415 Standardised pre-hospital care of acute myocardial infarction patients: MISSION! guidelines applied in practice. Atary JZ, de Visser M, van den Dijk R, Bosch J, Liem SS, Antoni ML, Bootsma M, Viergever EP, Kirchhof CJ, Padmos I, Sedney MI, van Exel HJ, Verwey HF, Atsma DE, van der Wal EE, Jukema JW, Schalij MJ
Background. To improve acute myocardial infarction (AMI) care in the region 'Hollands-Midden' (the Netherlands), a standardised guideline-based care program was developed (MISSION!). This study aimed to evaluate the outcome of the pre-hospital part of the MISSION! program and to study potential differences in pre-hospital care between four areas of residency.Methods. Time-to-treatment delays, AMI risk profile, cardiac enzymes, hospital stay, in-hospital mortality, and pre-AMI medicatio... Abstract
Cited 103 times since 2010 (7.5 per year) source: EuropePMC
European respiratory review : an official journal of the European Respiratory Society, Volume 19, Issue 117, 1 1 2010, Pages 197-203 The arterial load in pulmonary hypertension. Saouti N, Westerhof N, Postmus PE, Vonk-Noordegraaf A
The anatomical differences between the pulmonary and systemic arterial system are the main cause of the difference in distribution of compliance. In the pulmonary arterial system compliance is distributed over the entire arterial system, and stands at the basis of the constancy of the RC-time. This distribution depends on the number of peripheral vessels, which is ∼8-10 times more in the pulmonary system than the systemic tree. In the systemic arterial tree the compliance is mainly located in th... Abstract
Cited 5 times since 2010 (0.4 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 4, 1 1 2010, Pages 587-591 100 kV versus 120 kV: effective reduction in radiation dose? van der Wall EE, Jukema JW, Schuijf JD, Bax JJ
Cited 163 times since 2010 (11.9 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 38 Suppl, 1 1 2010, Pages S1-S52 Guidelines on myocardial revascularization. Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS), European Association for Percutaneous Cardiovascular Interventions (EAPCI), Kolh P, Wijns W, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, Lopez-Sendon J, Marco J, Menicanti L, Ostojic M, Piepoli MF, Pirlet C, Pomar JL, Reifart N, Ribichini FL, Schalij MJ, Sergeant P, Serruys PW, Silber S, Sousa Uva M, Taggart D
Cited 74 times since 2010 (5.4 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 6, 1 1 2010, Pages 694-700 Quantitative assessment of mitral regurgitation: comparison between three-dimensional transesophageal echocardiography and magnetic resonance imaging. Shanks M, Siebelink HM, Delgado V, van de Veire NR, Ng AC, Sieders A, Schuijf JD, Lamb HJ, Ajmone Marsan N, Westenberg JJ, Kroft LJ, de Roos A, Bax JJ
Background: quantification of mitral regurgitation severity with 2-dimensional (2D) imaging techniques remains challenging. The present study compared the accuracy of 2D transesophageal echocardiography (TEE) and 3-dimensional (3D) TEE for quantification of mitral regurgitation, using MRI as the reference method. Methods and results: two-dimensional and 3D TEE and cardiac MRI were performed in 30 patients with mitral regurgitation. Mitral effective regurgitant orifice area (EROA) and regurgitant... Abstract
Cited 14 times since 2010 (1 per year) source: EuropePMC
Anatomical sciences education, Volume 3, Issue 5, 1 1 2010, Pages 249-253 The role of medical museums in contemporary medical education. Marreez YM, Willems LN, Wells MR
From the early 19th century until the most recent two decades, open-space and satellite museums featuring anatomy and pathology collections (collectively referred to as "medical museums") had leading roles in medical education. However, many factors have caused these roles to diminish dramatically in recent years. Chief among these are the great advances in information technology and web-based learning that are currently at play in every level of medical training. Some medical schools... Abstract
Cited 2 times since 2010 (0.1 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 6, 1 1 2010, Pages 860-864 Influence of left ventricular dysfunction (diastolic versus systolic) on long-term prognosis in patients with versus without diabetes mellitus having elective peripheral arterial surgery. van Kuijk JP, Flu WJ, Valentijn TM, Chonchol M, Kuiper RJ, Verhagen HJ, Bax JJ, Poldermans D
Diabetes mellitus (DM) and left ventricular dysfunction (LVD) are often coexistent and invariably associated with increased mortality. Data on long-term prognosis of "isolated" diastolic LVD in diabetics are lacking; therefore, we evaluated these prognostic implications in patients with peripheral arterial disease (PAD) and DM. Using echocardiography, 1321 patients were screened for diastolic, systolic (ejection fraction 6.1 mmol/L were diagnosed with DM. The primary end point was occu... Abstract
Cited 2 times since 2010 (0.1 per year) source: EuropePMC
American heart journal, Volume 160, Issue 3, 1 1 2010, Pages 387-393 The efficacy and safety of clopidogrel in vascular surgery patients with immediate postoperative asymptomatic troponin T release for the prevention of late cardiac events: Rationale and design of the Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echo-VII (DECREASE-VII) trial. van Kuijk JP, Voute MT, Flu WJ, Schouten O, Chonchol M, Hoeks SE, Boersma EE, Verhagen HJ, Bax JJ, Poldermans D
Background: Major vascular surgery patients are at high risk for developing asymptomatic perioperative myocardial ischemia reflected by a postoperative troponin release without the presence of chest pain or electrocardiographic abnormalities. Long-term prognosis is severely compromised and characterized by an increased risk of long-term mortality and cardiovascular events. Current guidelines on perioperative care recommend single antiplatelet therapy with aspirin as prophylaxis for cardiovascula... Abstract
Cited 28 times since 2010 (2 per year) source: EuropePMC
Physical review. E, Statistical, nonlinear, and soft matter physics, Volume 82, Issue 2 Pt 2, 30 5 2010, Pages 026321 Microbubble shape oscillations excited through ultrasonic parametric driving. Versluis M, Goertz DE, Palanchon P, Heitman IL, van der Meer SM, Dollet B, de Jong N, Lohse D
An air bubble driven by ultrasound can become shape-unstable through a parametric instability. We report time-resolved optical observations of shape oscillations (mode n=2 to 6) of micron-sized single air bubbles. The observed mode number n was found to be linearly related to the ambient radius of the bubble. Above the critical driving pressure threshold for shape oscillations, which is minimal at the resonance of the volumetric radial mode, the observed mode number n is independent of the forci... Abstract
Cited 91 times since 2010 (6.6 per year) source: EuropePMC
European heart journal, Volume 31, Issue 21, 29 5 2010, Pages 2593-2600 A single dose of erythropoietin in ST-elevation myocardial infarction. Voors AA, Belonje AM, Zijlstra F, Hillege HL, Anker SD, Slart RH, Tio RA, van 't Hof A, Jukema JW, Peels HO, Henriques JP, Ten Berg JM, Vos J, van Gilst WH, van Veldhuisen DJ, HEBE III Investigators
Aims: Cardioprotective effects of erythropoietin (EPO) have been shown in experimental and smaller clinical studies. We performed a prospective, multicentre, randomized trial to assess the effects of a single high dose of EPO after primary coronary intervention (PCI) for an ST-elevation myocardial infarction (STEMI). Methods and results Patients with a successful PCI for a first STEMI were randomized to receive either standard medical care alone, or in combination with a single bolus with 60,000... Abstract
Cited 1345 times since 2010 (98 per year) source: EuropePMC
European heart journal, Volume 31, Issue 20, 29 5 2010, Pages 2501-2555 Guidelines on myocardial revascularization. Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS), European Association for Percutaneous Cardiovascular Interventions (EAPCI), Wijns W, Kolh P, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, Lopez-Sendon J, Marco J, Menicanti L, Ostojic M, Piepoli MF, Pirlet C, Pomar JL, Reifart N, Ribichini FL, Schalij MJ, Sergeant P, Serruys PW, Silber S, Sousa Uva M, Taggart D
Cited 5 times since 2010 (0.4 per year) source: EuropePMC
Annals of hematology, Volume 90, Issue 2, 28 4 2010, Pages 151-158 Severe congenital neutropenia in a multigenerational family with a novel neutrophil elastase (ELANE) mutation. van de Vosse E, Verhard EM, Tool AJ, de Visser AW, Kuijpers TW, Hiemstra PS, van Dissel JT
We have analysed a family with nine congenital neutropenia patients in four generations, several of which we have studied in a long-term follow-up of over 25 years. The patients were mild to severe neutropenic and suffered from various recurrent bacterial infections. Mutations in the genes ELANE, CSF3R and GFI1 have been reported in patients with autosomal dominant congenital neutropenias. Using a small-scale linkage analysis with markers around the ELANE, CSF3R, CSF3 and GFI1 genes, we were abl... Abstract
Cited 94 times since 2010 (6.8 per year) source: EuropePMC
The Journal of nutrition, Volume 140, Issue 10, 25 4 2010, Pages 1774-1780 Oral nutritional supplements containing (n-3) polyunsaturated fatty acids affect the nutritional status of patients with stage III non-small cell lung cancer during multimodality treatment. van der Meij BS, Langius JA, Smit EF, Spreeuwenberg MD, von Blomberg BM, Heijboer AC, Paul MA, van Leeuwen PA
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), (n-3) fatty acids from fish oil, have immune-modulating effects and may improve nutritional status in cancer. The objective of this study was to investigate the effects of an oral nutritional supplement containing (n-3) fatty acids on nutritional status and inflammatory markers in patients with non-small cell lung cancer (NSCLC) undergoing multimodality treatment. In a double-blind experiment, 40 patients with stage III NSCLC were rando... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 1, 24 4 2010, Pages 101-104 Speckle tracking: distinction of physiologic from pathologic LVH? van der Wall EE, Delgado V, Holman ER, Bax JJ
Cited 39 times since 2010 (2.8 per year) source: EuropePMC
Cell transplantation, Volume 20, Issue 2, 18 3 2010, Pages 217-231 Long-term contribution of human bone marrow mesenchymal stromal cells to skeletal muscle regeneration in mice. de la Garza-Rodea AS, van der Velde I, Boersma H, Gonçalves MA, van Bekkum DW, de Vries AA, Knaän-Shanzer S
Mesenchymal stromal cells (MSCs) are attractive for cellular therapy of muscular dystrophies as they are easy to procure, can be greatly expanded ex vivo, and contribute to skeletal muscle repair in vivo. However, detailed information about the contribution of bone marrow (BM)-derived human MSCs (BM-hMSCs) to skeletal muscle regeneration in vivo is very limited. Here, we present the results of a comprehensive study of the fate of LacZ-tagged BM-hMSCs following implantation in cardiotoxin (CTX)-i... Abstract