Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7490 results
Cited 14 times since 1985 (0.4 per year) source: EuropePMC
Archives of internal medicine, Volume 145, Issue 8, 1 1 1985, Pages 1513-1515 A case of carbimazole-induced intrahepatic cholestasis. An immune-mediated reaction? Blom H, Stolk J, Schreuder HB, von Blomberg-van der Flier M
A patient is described with cholestatic hepatitis following the use of carbimazole. A liver biopsy specimen showed intracanalicular cholestasis and some mononuclear cell infiltrate in the portal triades, consistent with drug toxicity; indications of an autoimmune or viral pathogenesis were absent. Rechallenge with the drug precipitated jaundice and disturbed liver function once more. Carbimazole induced a blastogenic response of patient lymphocytes in vitro. Both may suggest the involvement of a... Abstract
Cited 9 times since 1985 (0.2 per year) source: EuropePMC
Thrombosis research, Volume 38, Issue 5, 1 1 1985, Pages 491-503 Activation of factor B of the complement system by kallikrein and its light chain. Hiemstra PS, Daha MR, Bouma BN
The cleavage of factor B, a protein of the alternative pathway of complement, by kallikrein was studied. Like factor D, kallikrein can cleave B to generate the alternative pathway C3 convertase C3bBb. When this convertase was formed on erythrocytes previously coated with C3b, lysis was observed indicating that a functionally active C3 convertase was formed. B was also cleaved by kallikrein in the presence of fluid phase C3b, and this resulted in B fragments comparable in size to those generated... Abstract
Cited 2 times since 1985 (0.1 per year) source: EuropePMC
European journal of radiology, Volume 5, Issue 2, 1 1 1985, Pages 99-103 DSA--a helpful tool in diagnosis of aberrant left pulmonary artery (vascular sling) in adults. Mooyaart EL, Boomsma JH, Postmus PE, Formanek GA
Two new adult patients with aberrant origin of the left pulmonary artery from the right pulmonary artery--pulmonary artery sling--are described, totalling the published adult cases to eight. Differentiation from a mediastinal mass closely mimicking this vascular anomaly is discussed. For the definitive diagnosis, digital subtraction angiography was applied for the first time. The clearest demonstration of the anatomy is in 20-25 degrees RPO and 20-25 degrees sitting position. The aberrant left p... Abstract
Cited 42 times since 1985 (1.1 per year) source: EuropePMC
Cancer research, Volume 45, Issue 5, 1 1 1985, Pages 2192-2200 Neuroendocrine differentiation antigen on human lung carcinoma and Kulchitski cells. de Leij L, Poppema S, Nulend JK, ter Haar A, Schwander E, Ebbens F, Postmus PE, The TH
In the normal lung, a subset of cells with a histological appearance consistent with that of Kulchitski cells are the only lung cells reacting with a monoclonal antibody (MOC-1) raised against a human small cell lung carcinoma-derived cell line. Outside the lung, a subset of normal endocrine cells (in the adrenal, thyroid, ovary, and pancreas) as well as neural cells (brain and peripheral Schwann cells) also express the antigen detected by MOC-1 (named MOC-1-related antigen). Some of these posit... Abstract
Cited 40 times since 1984 (1 per year) source: EuropePMC
Cancer treatment reports, Volume 68, Issue 12, 1 1 1984, Pages 1471-1474 High-dose etoposide for refractory malignancies: a phase I study. Postmus PE, Mulder NH, Sleijfer DT, Meinesz AF, Vriesendorp R, de Vries EG
Etoposide is active against a number of solid tumors when used in a standard dose. The toxicity at a standard dose level is mild myelosuppression without extramedullary toxicity. Recent studies in man support the dose-response relationship of etoposide. In a group of 22 patients with progressive disseminated malignancies, the dose of etoposide was escalated to define dose-limiting extramedullary toxicity, which was oropharyngeal mucositis at a dose level of 3.5 g/m2. Bone marrow toxicity was com... Abstract
Cited 5 times since 1984 (0.1 per year) source: EuropePMC
Blut, Volume 49, Issue 5, 1 1 1984, Pages 419-421 No narcosis for bone marrow harvest in autologous bone marrow transplantation. de Vries EG, Vriesendorp R, Meinesz AF, Mulder NH, Postmus PE, Sleijfer DT
A prospective study with mild general analgesia and sedation together with local anesthesia during bone marrow harvest was performed. Thirty-one patients underwent 33 bone marrow collections. Pretreatment consisted of 100 mg meperidine i.m. and 20 mg diazepam i.m. 1 h before start of procedure. Eight patients got additional meperidine and diazepam during the procedure, all patients got lidocaine 1% locally. A mean volume of 1.321 was obtained with 42.5 punctures. Twenty-two patients had no compl... Abstract
Cited 5 times since 1984 (0.1 per year) source: EuropePMC
Annals of internal medicine, Volume 101, Issue 5, 1 1 1984, Pages 717 Remission of brain metastases from small-cell lung cancer after high-dose chemotherapy. Postmus PE, Haaxma-Reiche H, Vencken LM, Meinesz AF, Sleijfer DT, Mulder NH
Cited 517 times since 1984 (13.1 per year) source: EuropePMC
Circulation, Volume 70, Issue 5, 1 1 1984, Pages 812-823 Continuous measurement of left ventricular volume in animals and humans by conductance catheter. Baan J, van der Velde ET, de Bruin HG, Smeenk GJ, Koops J, van Dijk AD, Temmerman D, Senden J, Buis B
An eight-electrode conductance catheter previously developed by us and used to determine stroke volume in dogs was applied in human beings and dogs to measure absolute left ventricular volume quantitatively. For calibration we developed the formula V(t) = (1/alpha)(L2/sigma b)G(t) - Vc, where V(t) is time-varying left ventricular volume, alpha is a dimensionless constant, L is the electrode separation, sigma b is the conductivity of blood obtained by a sampling cuvette, and G(t) is the measured... Abstract
Cited 17 times since 1984 (0.4 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 20, Issue 6, 1 1 1984, Pages 777-782 Cyclophosphamide and VP 16-213 with autologous bone marrow transplantation. A dose escalation study. Postmus PE, de Vries EG, De Vries-Hospers HG, Vriesendorp R, van Imhoff GW, Holthuis JJ, Sibinga CT, Sleijfer DT, Mulder NH
In 13 patients with therapy-resistant solid tumors the feasibility of high-dose cyclophosphamide (7 g/m2) in combination with increasing doses of VP 16-213 with autologous bone marrow transplantation was studied. Dose-limiting extramedullary toxicity appeared to be mucositis and occurred after 2.5 g/m2. Two toxic deaths were observed in patients older than 55 yr. Responses were seen in eight out of nine evaluable patients. Two patients with ovarian cancer still have no signs of disease progressi... Abstract
Cited 22 times since 1984 (0.5 per year) source: EuropePMC
Journal of applied physiology: respiratory, environmental and exercise physiology, Volume 56, Issue 4, 1 1 1984, Pages 1053-1059 Breathing pattern during induced bronchoconstriction. Chadha TS, Schneider AW, Birch S, Jenouri G, Sackner MA
The breathing patterns of normal subjects monitored with respiratory inductive plethysmography were investigated after mild increases in respiratory resistance provoked by aerosolized methacholine during natural breathing and while breathing on a mouthpiece to a pneumotachograph. First, during natural breathing, comparisons of inspiratory ventilation (VI), tidal volume (VT), frequency (f), inspiratory time (TI), fractional inspiratory time (TI/TT), and mean inspiratory flow (VT/TI) were made bef... Abstract
Cited 13 times since 1984 (0.3 per year) source: EuropePMC
Gynecologic oncology, Volume 17, Issue 3, 1 1 1984, Pages 271-276 Effective high-dose chemotherapy with autologous bone marrow infusion in resistant ovarian cancer. Vriesendorp R, Aalders JG, Sleijfer DT, Postmus PE, Willemse PH, Bouma J, Mulder NH
Two patients with persistent minimal ovarian cancer after conventional polychemotherapy were treated with high doses of cyclophosphamide and VP 16-213 followed by autologous bone marrow infusion. Ten months afterward no clinical signs of tumor were apparent. In one patient the complete response was surgically documented. Toxicity included cardiac and pulmonary arrest during marrow infusion in one patient, but was otherwise manageable. This method of late intensification of chemotherapy in patien... Abstract
Cited 45 times since 1984 (1.1 per year) source: EuropePMC
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 2, Issue 3, 1 1 1984, Pages 215-220 Penetration of VP 16-213 into cerebrospinal fluid after high-dose intravenous administration. Postmus PE, Holthuis JJ, Haaxma-Reiche H, Mulder NH, Vencken LM, van Oort WJ, Sleijfer DT, Sluiter HJ
VP 16-213 in standard doses is active against a number of solid tumors. Its penetration into the cerebrospinal fluid (CSF) is very limited at these dose levels. In 10 patients treated with high-dose VP 16-213 (0.9-2.5 g/m2), CSF levels of up to 0.54 microgram/mL were detected. In two patients with central nervous system (CNS) metastases of small cell lung cancer (SCLC) a response was seen after 1.0 and 1.5 g/m2 intravenously. High-dose VP 16-213 can possibly play a role in the treatment of CNS m... Abstract
Cited 4 times since 1984 (0.1 per year) source: EuropePMC
Cancer, Volume 53, Issue 3, 1 1 1984, Pages 396-400 Small cell lung cancer and the influence of chemotherapy on CFUcs in bone marrow. Postmus PE, Mulder NH, de Vries EG, van Luyn M, Halie MR
To determine the optimal moment for the harvesting of bone marrow for autologous transplantation, the authors did serially colony forming units in culture (CFUc) counts in a group of 42 patients with small cell lung cancer (SCLC) before and after remission induction chemotherapy and subsequent maintenance chemotherapy. Disease stage did not influence the CFUc count except in patients with bone marrow metastases; this resulted in either abnormally low or abnormally high CFUc counts, probably depe... Abstract
Cited 4 times since 1984 (0.1 per year) source: EuropePMC
The Netherlands journal of medicine, Volume 27, Issue 10, 1 1 1984, Pages 389-392 Feasibility of high dose VP 16-213 as single agent or in combination with cyclophosphamide and autologous bone marrow transplantation (ABMT). Mulder NH, Meinesz AF, Sleijfer DT, Postmus PE, De Vries EG, Van der Geest S, Orie JL, Vriesendorp R
Cited 6 times since 1983 (0.1 per year) source: EuropePMC
Blut, Volume 47, Issue 4, 1 1 1983, Pages 203-209 Autologous cryopreserved platelets and prophylaxis of bleeding in autologous bone marrow transplantation. van Imhoff GW, Arnaud F, Postmus PE, Mulder NH, Das PC, Smit Sibinga CT
Autologous platelets were harvested and cryopreserved in eight consecutive patients elected for ablative chemotherapy and autologous bone marrow transplantation (ABMT) for solid malignancy. There was a 19% loss in platelet count after the freeze thaw and wash procedure; with an in vitro functional loss of 40-60%. No correlation could be found for individual platelet transfusions between in vitro functional tests and in vivo recovery. Six consecutive patients received a total of 16 autologous pla... Abstract
Cited 13 times since 1983 (0.3 per year) source: EuropePMC
Cancer treatment reports, Volume 67, Issue 1, 1 1 1983, Pages 21-26 Complications of treatment of small cell carcinoma of the lung. Abeloff MD, Klastersky J, Drings PD, Eagan RT, Greco FA, Holsti L, Mattson K, Postmus PE
Improvements in therapy for small cell carcinoma of the lung have been achieved with treatment regimens that result in significant toxicity. The workshop of the International Association for the Study of Lung Cancer focused on the following complications of chemotherapy and radiotherapy: leukopenia and resultant infections, esophagitis, pneumonitis and pulmonary fibrosis, cardiac toxicity, second malignancies, neurologic complications, and psychosocial effects. The data regarding the incidence a... Abstract
Cited 7 times since 1982 (0.2 per year) source: EuropePMC
Clinical science (London, England : 1979), Volume 63, Issue 5, 1 1 1982, Pages 473-483 Breathing pattern during and after smoking cigarettes. Tobin MJ, Schneider AW, Sackner MA
Cited 167 times since 1982 (4 per year) source: EuropePMC
The American review of respiratory disease, Volume 125, Issue 6, 1 1 1982, Pages 644-649 Validation of respiratory inductive plethysmography using different calibration procedures. Chadha TS, Watson H, Birch S, Jenouri GA, Schneider AW, Cohn MA, Sackner MA
We devised a new calibration procedure [least squares method (LSQ)] for respiratory inductive plethysmography (RIP) and compared it with our previously reported simultaneous equation method (SEQ) of analyzing data in 2 body positions and with the method of Stagg and associates using the analysis of individual breaths in a single body position. The values from RIP were compared with simultaneous spirometry (SP) in 20 normal subjects placed in the standing (STD), supine (SUP), sitting, prone, semi... Abstract
Nederlands tijdschrift voor geneeskunde, Volume 126, Issue 20, 1 1 1982, Pages 906-913 [The treatment of patients with lung carcinoma]. van der Wal AM, Elema JD, Jansen HM, Luursema PB, Postmus PE, Sleyfer DT, Vermey J
Cited 162 times since 1981 (3.8 per year) source: EuropePMC
Cardiovascular research, Volume 15, Issue 6, 1 1 1981, Pages 328-334 Continuous stroke volume and cardiac output from intra-ventricular dimensions obtained with impedance catheter. Baan J, Jong TT, Kerkhof PL, Moene RJ, van Dijk AD, van der Velde ET, Koops J
To improve assessment of ventricular function during cardiac catheterisation there should be available a continuous registration of stroke volume and cardiac output in addition to ventricular pressure. To obtain the desired volumetric quantities a catheter has been developed which measures changes in intraventricular dimensions by electrical impedance. For this purpose, the catheter is equipped with eight electrodes spaced over a distance equal to the long axis of the left ventricle into which i... Abstract