Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
251 results
Cited 7 times since 2006 (0.4 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 1, Issue 4, 1 1 2006, Pages 417-424 Myocardial repair by percutaneous cell transplantation of autologous skeletal myoblast as a stand alone procedure in post myocardial infarction chronic heart failure patients. Smits PC, Nienaber C, Colombo A, Ince H, Carlino M, Theuns DA, Biagini E, Valgimigli M, Onderwater EE, Steendijk P, Peters NS, Goedhart DM, Serruys PW
Aims: In this first multicentre study we assessed the safety and efficacy of percutaneous transendocardial skeletal myoblast injection as a stand alone procedure in congestive heart failure patients. Methods and results: 15 patients (14 male), age 63+/-7 (Mean+/-SD), NYHA class 2-4 were injected with 216+/-119 cells (81+/-19% Desmin+) using a NOGA or fluoroscopy guided injection catheter. The cells were injected in the scarred regions 6+/-4 years after myocardial infarction as a stand alone proc... Abstract
Cited 3 times since 2006 (0.2 per year) source: EuropePMC
Critical care medicine, Volume 34, Issue 2, 1 1 2006, Pages 545-547 The role of inducible nitric oxide synthase in the evolution of myocardial (dys)function during resuscitated septic shock: the missing loop. Steendijk P
Cited 25 times since 2006 (1.4 per year) source: EuropePMC
ASAIO journal (American Society for Artificial Internal Organs : 1992), Volume 52, Issue 1, 1 1 2006, Pages 4-8 Modeling ventricular function during cardiac assist: does time-varying elastance work? Vandenberghe S, Segers P, Steendijk P, Meyns B, Dion RA, Antaki JF, Verdonck P
The time-varying elastance theory of Suga et al. is widely used to simulate left ventricular function in mathematical models and in contemporary in vitro models. We investigated the validity of this theory in the presence of a left ventricular assist device. Left ventricular pressure and volume data are presented that demonstrate the heart-device interaction for a positive-displacement pump (Novacor) and a rotary blood pump (Medos). The Novacor was implanted in a calf and used in fixed-rate mode... Abstract
Critical care medicine, Volume 34, Issue 1, 1 1 2006, Pages 255-257 The role of nitric oxide signaling in sepsis-induced myocardial dysfunction. Steendijk P
Cited 23 times since 2005 (1.2 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 28, Issue 12, 1 1 2005, Pages 1271-1275 Does a gender difference in response to cardiac resynchronization therapy exist? Bleeker GB, Schalij MJ, Boersma E, Steendijk P, van der Wall EE, Bax JJ
Background: Cardiac resynchronization therapy (CRT) has a beneficial effect on clinical symptoms, exercise capacity, and systolic left ventricular (LV) performance in patients with heart failure. The aim of the current study was to evaluate whether a gender difference exists in response to CRT. Methods: Consecutive patients with end-stage heart failure (New York Heart Association, NYHA, class III-IV), LV ejection fraction (LVEF) < or =35%, QRS duration >120 ms, and left bundle branch block... Abstract
Cited 67 times since 2005 (3.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 46, Issue 12, 1 1 2005, Pages 2264-2269 Left ventricular dyssynchrony predicts right ventricular remodeling after cardiac resynchronization therapy. Bleeker GB, Schalij MJ, Nihoyannopoulos P, Steendijk P, Molhoek SG, van Erven L, Bootsma M, Holman ER, van der Wall EE, Bax JJ
Objectives: The purpose of this research was to evaluate right ventricular (RV) remodeling after six months of cardiac resynchronization therapy (CRT). Background: Cardiac resynchronization therapy is beneficial in patients with end-stage heart failure. The effect of CRT on RV size is currently unknown. Accordingly, the effects of CRT on RV size, severity of tricuspid regurgitation, and pulmonary artery pressure were evaluated. Methods: Fifty-six consecutive patients with end-stage heart failure... Abstract
Cited 1 times since 2005 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 22, Issue 2, 25 4 2005, Pages 167-169 Failure to decrease blood pressure during sleep: non-dippers are among us. Steendijk P
Cited 18 times since 2005 (1 per year) source: EuropePMC
Basic research in cardiology, Volume 101, Issue 1, 11 2 2005, Pages 36-42 Suppression of physiological cardiomyocyte proliferation in the rat pup after neonatal glucocorticosteroid treatment. de Vries WB, Bal MP, Homoet-van der Kraak P, Kamphuis PJ, van der Leij FR, Baan J, Steendijk P, de Weger RA, van Bel F, van Oosterhout MF
Background: Glucocorticosteroids (mostly dexamethasone) are widely used to prevent chronic lung disease in premature infants. Neonatal rats treated with dexamethasone have been shown to have reduced cardiac mass and cardiomyocyte hypertrophy, suggesting a lower number of cardiomyocytes at adult age, and a severely reduced life expectancy. In the present study we tested the hypothesis that a lower number of cardiomyocytes in later life is caused by a reduced cardiomyocyte proliferation and/or by... Abstract
Cited 5 times since 2005 (0.3 per year) source: EuropePMC
Acta physiologica Scandinavica, Volume 185, Issue 3, 1 1 2005, Pages 181-191 Left ventricular pressure-volume relationships during normal growth and development in the adult rat--studies in 8- and 50-week-old male Wistar rats. Bal MP, de Vries WB, van der Leij FR, van Oosterhout MF, Baan J, van der Wall EE, van Bel F, Steendijk P
Aims: Left ventricular (LV) pressure-volume relations provide relatively load-independent indexes of systolic and diastolic LV function, but few data are available on pressure-volume relations during growth and development in the normal adult heart. Furthermore, to quantify intrinsic ventricular function the indexes should be normalized for heart weight. However, in many studies the indexes are reported in absolute terms, or body weight-correction is used as a surrogate for heart weight-correcti... Abstract
Cited 58 times since 2005 (3.1 per year) source: EuropePMC
European journal of heart failure, Volume 8, Issue 2, 7 1 2005, Pages 115-121 Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy. Westermann D, Knollmann BC, Steendijk P, Rutschow S, Riad A, Pauschinger M, Potter JD, Schultheiss HP, Tschöpe C
Background: The cardiac troponin T I79N mutation, linked to familial hypertrophic cardiomyopathy, carries a high risk of sudden cardiac death even in the absence of significant cardiac hypertrophy. The pathology underlying this mechanism has not yet been identified. Aims: To study the underlying mechanism of this phenomenon we characterized the left ventricular (LV) performance of transgenic mice carrying the human troponin T mutation I79N under basal and isoproterenol-induced stress conditions.... Abstract
Cited 12 times since 2005 (0.6 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 12, Issue 5, 1 1 2005, Pages 545-552 Hemodynamic evaluation of saphenous vein coronary artery bypass grafts: relative merits of Doppler flow velocity and SPECT perfusion imaging. Salm LP, Bax JJ, Jukema JW, Langerak SE, Vliegen HW, Steendijk P, Lamb HJ, de Roos A, van der Wall EE
Background: Coronary angiography is considered the gold standard in evaluating vein graft disease; however, angiography does not allow assessment of hemodynamic consequences of lesions. In this study hemodynamic consequences of significant stenoses in vein grafts were evaluated by Doppler velocity assessment, and results were compared with single photon emission computed tomography (SPECT) perfusion imaging. Methods and results: Angiography was performed in 58 patients after coronary artery bypa... Abstract
Cited 93 times since 2005 (4.9 per year) source: EuropePMC
Circulation, Volume 112, Issue 9 Suppl, 1 1 2005, Pages I212-8 Right atrial and ventricular adaptation to chronic right ventricular pressure overload. Gaynor SL, Maniar HS, Bloch JB, Steendijk P, Moon MR
Background: Increased mortality in patients with chronic pulmonary hypertension has been associated with elevated right atrial (RA) pressure. However, little is known about the effects of chronic right ventricular (RV) pressure overload on RA and RV dynamics or the adaptive response of the right atrium to maintain RV filling. Methods and results: In 7 dogs, RA and RV pressure and volume (conductance catheter) were recorded at baseline and after 3 months of progressive pulmonary artery banding. R... Abstract
Cited 38 times since 2005 (2 per year) source: EuropePMC
The American journal of cardiology, Volume 96, Issue 3, 1 1 2005, Pages 420-422 Comparison of effectiveness of cardiac resynchronization therapy in patients <70 versus > or =70 years of age. Bleeker GB, Schalij MJ, Molhoek SG, Boersma E, Steendijk P, van der Wall EE, Bax JJ
In the present study, the effects of cardiac resynchronization therapy (CRT) in elderly patients were evaluated. The study included 170 consecutive patients whose clinical and echocardiographic improvements were evaluated after 6 months of follow-up. Survival was evaluated up to 2 years. The effects of CRT in elderly patients (age > or =70 years) were compared with those in younger patients (age Abstract
Cited 11 times since 2005 (0.6 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 130, Issue 1, 1 1 2005, Pages 33-40 Acute hemodynamic effects of restrictive mitral annuloplasty in patients with end-stage heart failure: analysis by pressure-volume relations. Tulner SA, Steendijk P, Klautz RJ, Bax JJ, Versteegh MI, van der Wall EE, Dion RA
Objective: Recent studies show beneficial long-term effects of restrictive mitral annuloplasty in patients with end-stage heart failure. However, concerns are raised about possible adverse effects on early postoperative systolic and diastolic function, which might limit application of this approach in patients with heart failure. Therefore we evaluated the acute effects of restrictive mitral annuloplasty on left ventricular function by using load-independent pressure-volume relations. Methods: I... Abstract
Cited 25 times since 2005 (1.3 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 16, Issue 7, 1 1 2005, Pages 701-707 Long-term follow-up of cardiac resynchronization therapy in patients with end-stage heart failure. Molhoek SG, Bax JJ, Bleeker GB, Holman ER, Van Erven L, Bootsma M, Boersma E, Steendijk P, Van Der Wall EE, Schalij MJ
Unlabelled: Long-term follow-up of cardiac resynchronization therapy. Introduction: Cardiac resynchronization therapy (CRT) has been introduced to treat patients with end-stage heart failure, and results of this technique are promising. The aim of our study was to assess the sustained benefit of CRT in a large patient cohort with end-stage heart failure at long-term follow-up. In addition, the prognosis of responders and nonresponders was evaluated. Methods and results: 125 patients with end-sta... Abstract
Cited 17 times since 2005 (0.9 per year) source: EuropePMC
The American journal of cardiology, Volume 96, Issue 1, 1 1 2005, Pages 108-111 Comparison of effectiveness of cardiac resynchronization therapy in patients with versus without diabetes mellitus. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
The effect of long-term cardiac resynchronization therapy (CRT) was evaluated in 32 patients with heart failure (HF) and diabetes mellitus (DM) compared with 65 patients with HF and no DM. Clinical parameters were obtained before and after 6 months of CRT. Long-term follow-up was performed Abstract
Cited 21 times since 2005 (1.1 per year) source: EuropePMC
Pediatric research, Volume 58, Issue 1, 27 4 2005, Pages 46-52 Neonatal glucocorticosteroid treatment causes systolic dysfunction and compensatory dilation in early life: studies in 4-week-old prepubertal rats. Bal MP, de Vries WB, van der Leij FR, van Oosterhout MF, Berger RM, Baan J, van der Wall EE, van Bel F, Steendijk P
Glucocorticosteroid treatment is widely used to prevent chronic lung disease in premature infants. Recent studies in adult rats, treated with dexamethasone in the neonatal period, report negative long-term effects on the heart and severely reduced life expectancy. We treated neonatal rats with dexamethasone and studied cardiac function after 4 wk (prepubertal age) to investigate whether the late effects as previously described are preceded by detectable alterations in cardiac function at a young... Abstract
Cited 68 times since 2005 (3.6 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 65, Issue 2, 1 1 2005, Pages 263-267 Left ventricular unloading and concomitant total cardiac output increase by the use of percutaneous Impella Recover LP 2.5 assist device during high-risk coronary intervention. Valgimigli M, Steendijk P, Sianos G, Onderwater E, Serruys PW
A number of techniques have been proposed for circulatory support during high-risk percutaneous coronary interventions (PCI), but no single approach has achieved wide acceptance so far. We report on a patient with severe left ventricular (LV) impairment who underwent a PCI with the use of a new left ventricular assist device, the Impella Recover LP 2.5 system. The effects on global cardiac output were determined by thermodilution (TD) and LV pressure-volume loops obtained by conductance catheter... Abstract
Cited 16 times since 2005 (0.8 per year) source: EuropePMC
The American journal of cardiology, Volume 95, Issue 9, 1 1 2005, Pages 1111-1114 Effect of cardiac resynchronization therapy on inducibility of ventricular tachyarrhythmias in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, Bootsma M, van Erven L, Steendijk P, van der Wall EE, Schalij MJ
We evaluated whether long-term cardiac resynchronization therapy affects the inducibility of ventricular tachyarrhythmias in relation to reverse remodeling in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. Clinical, electrophysiologic, and echocardiographic data of 18 patients were obtained before and after 6 months of cardiac resynchronization. Abstract
Critical care medicine, Volume 33, Issue 5, 1 1 2005, Pages 1157-1158 Going on and on with NO? Steendijk P