Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
105 results
Cited 5 times since 2013 (0.5 per year) source: Scopus
The American journal of cardiology, Volume 112, Issue 5, 24 4 2013, Pages 714-719 Mitral valve geometry and hemodynamics after surgical mitral valve annuloplasty and implications for percutaneous treatment of patients with recurrent mitral regurgitation. Al Amri I, Debonnaire P, Witkowski T, van der Kley F, Palmen M, de Weger A, Klautz RJ, Bax JJ, Schalij MJ, Ajmone Marsan N, Delgado V
The feasibility of transcatheter mitral valve therapy (edge-to-edge or valve-in-ring technique) in patients with significant mitral regurgitation (MR) recurrence after surgical restrictive mitral valve annuloplasty remains unknown. The aim of the present study was to investigate the eligibility for transcatheter mitral valve therapy of high-surgical-risk patients with significant MR recurrence after initial successful restrictive mitral valve annuloplasty. A total of 47 patients (age 67 ± 10 yea... Abstract
Cited 23 times since 2013 (2.1 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 26, Issue 7, 11 2 2013, Pages 691-698 Impact of valvuloarterial impedance on 2-year outcome of patients undergoing transcatheter aortic valve implantation. Katsanos S, Yiu KH, Clavel MA, Rodés-Cabau J, Leong D, van der Kley F, Ajmone Marsan N, Bax JJ, Pibarot P, Delgado V
Background: Elderly patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) often have increased calcification and fibrosis of the aorta. Indices that account for the severity of valvular obstruction and systemic vascular impedance may better assess total left ventricular afterload. The aims of the present study were to evaluate changes in valvuloarterial impedance (Zva), systemic arterial compliance, and systemic vascular resistance after TAVI and to inves... Abstract
Cited 100 times since 2013 (9 per year) source: Scopus
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 44, Issue 1, 25 4 2013, Pages e8-15 Transcatheter valve-in-ring implantation after failure of surgical mitral repair. Descoutures F, Himbert D, Maisano F, Casselman F, de Weger A, Bodea O, Van der Kley F, Colombo A, Giannini C, Rein KA, De Bruyne B, Petronio AS, Dahle G, Alfieri O, Vahanian A
Objectives: Redo surgery after failed mitral valve repair may be high risk, or contraindicated in patients with comorbidities. Because of this high risk, other interventional possibilities like transcatheter valve implantation might be of benefit. We report our experience with transcatheter mitral valve-in-ring implantation (TVIR) in high-risk patients after failure of surgical ring annuloplasty. Methods: From January 2010 to February 2012, following a multidisciplinary discussion, 17 high-risk... Abstract
Cited 1 times since 2013 (0.1 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 8, Issue 9, 1 1 2013, Pages 1103-1109 How should I treat acute aortic annulus rupture during transcatheter aortic valve implantation? Debonnaire P, Van Herck PL, Katsanos S, van der Kley F, de Weger A, Palmen M, Marsan NA, Schalij MJ, Delgado V
Cited 141 times since 2012 (11.9 per year) source: EuropePMC
Circulation, Volume 126, Issue 6, 12 2 2012, Pages 720-728 Left bundle-branch block induced by transcatheter aortic valve implantation increases risk of death. Houthuizen P, Van Garsse LA, Poels TT, de Jaegere P, van der Boon RM, Swinkels BM, Ten Berg JM, van der Kley F, Schalij MJ, Baan J, Cocchieri R, Brueren GR, van Straten AH, den Heijer P, Bentala M, van Ommen V, Kluin J, Stella PR, Prins MH, Maessen JG, Prinzen FW
Background: Transcatheter aortic valve implantation (TAVI) is a novel therapy for treatment of severe aortic stenosis. Although 30% to 50% of patients develop new left bundle-branch block (LBBB), its effect on clinical outcome is unclear. Methods and results: Data were collected in a multicenter registry encompassing TAVI patients from 2005 until 2010. The all-cause mortality rate at follow-up was compared between patients who did and did not develop new LBBB. Of 679 patients analyzed, 387 (57.0... Abstract
Cited 172 times since 2011 (13.5 per year) source: Scopus
The American journal of cardiology, Volume 108, Issue 10, 17 3 2011, Pages 1470-1477 Location and severity of aortic valve calcium and implications for aortic regurgitation after transcatheter aortic valve implantation. Ewe SH, Ng AC, Schuijf JD, van der Kley F, Colli A, Palmen M, de Weger A, Marsan NA, Holman ER, de Roos A, Schalij MJ, Bax JJ, Delgado V
Location of aortic valve calcium (AVC) can be better visualized on contrast-enhanced multidetector row computed tomography. The present evaluation examined whether AVC severity and its location could influence paravalvular aortic regurgitation (AR) after transcatheter aortic valve implantation. A total of 79 patients (age 80 ± 7 years, 49% men) with preprocedural multidetector row computed tomography were included. Volumetric AVC quantification and its location were assessed. Transesophageal ech... Abstract
Cited 19 times since 2011 (1.5 per year) source: Scopus
European heart journal, Volume 32, Issue 22, 23 4 2011, Pages 2806-2813 Influence of left ventricular geometry and function on aortic annular dimensions as assessed with multi-detector row computed tomography: implications for transcatheter aortic valve implantation. Ng AC, Yiu KH, Ewe SH, van der Kley F, Bertini M, de Weger A, de Roos A, Leung DY, Schuijf JD, Schalij MJ, Bax JJ, Delgado V
Aims: Evaluate changes in aortic annular dimensions in relation to severe aortic stenosis (AS) and left ventricular (LV) dysfunction. Methods and results: Mean aortic annular diameters and geometries were compared between 90 severe AS patients and 111 controls by multi-detector row computed tomography (MDCT). All severe AS patients were also dichotomized into two groups based on the presence of preserved (≥ 50%) or impaired ( Abstract
Cited 104 times since 2011 (7.9 per year) source: EuropePMC
European heart journal, Volume 32, Issue 12, 29 5 2011, Pages 1542-1550 Alterations in multidirectional myocardial functions in patients with aortic stenosis and preserved ejection fraction: a two-dimensional speckle tracking analysis. Ng AC, Delgado V, Bertini M, Antoni ML, van Bommel RJ, van Rijnsoever EP, van der Kley F, Ewe SH, Witkowski T, Auger D, Nucifora G, Schuijf JD, Poldermans D, Leung DY, Schalij MJ, Bax JJ
Aims: To identify changes in multidirectional strain and strain rate (SR) in patients with aortic stenosis (AS). Methods and results: A total of 420 patients (age 66.1 ± 14.5 years, 60.7% men) with aortic sclerosis, mild, moderate, and severe AS with preserved left ventricular (LV) ejection fraction [(EF), ≥50%] were included. Multidirectional strain and SR imaging were performed by two-dimensional speckle tracking. Patients were more likely to be older (P < 0.001) and at a worse New York Hea... Abstract
Cited 70 times since 2011 (5.3 per year) source: Scopus
The Annals of thoracic surgery, Volume 92, Issue 4, 21 3 2011, Pages 1244-1251 Outcomes after transcatheter aortic valve implantation: transfemoral versus transapical approach. Ewe SH, Delgado V, Ng AC, Antoni ML, van der Kley F, Marsan NA, de Weger A, Tavilla G, Holman ER, Schalij MJ, Bax JJ
Background: Transcatheter aortic valve implantation is commonly implanted through a transfemoral (TFA) or transapical approach (TAA) for patients with severe aortic stenosis. This study aimed to describe the clinical and echocardiographic outcomes of TFA versus TAA. Methods: Clinical and echocardiographic evaluations were performed at baseline, post-TAVI (transcatheter aortic valve implantation), at 6 and 12 months follow-up in 107 consecutive patients who underwent TAVI with balloon-expandable... Abstract
Cited 31 times since 2011 (2.4 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 91, Issue 3, 1 1 2011, Pages 716-723 Automated assessment of the aortic root dimensions with multidetector row computed tomography. Delgado V, Ng AC, Schuijf JD, van der Kley F, Shanks M, Tops LF, van de Veire NR, de Roos A, Kroft LJ, Schalij MJ, Bax JJ
Background: Accurate aortic root measurements and evaluation of spatial relationships with coronary ostia are crucial in preoperative transcatheter aortic valve implantation assessments. Standardization of measurements may increase intraobserver and interobserver reproducibility to promote procedural success rate and reduce the frequency of procedurally related complications. This study evaluated the accuracy and reproducibility of a novel automated multidetector row computed tomography (MDCT) i... Abstract
Cited 117 times since 2010 (8.7 per year) source: Scopus
American heart journal, Volume 160, Issue 6, 1 1 2010, Pages 1113-1120 Impact of left ventricular systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation for severe aortic stenosis. Ewe SH, Ajmone Marsan N, Pepi M, Delgado V, Tamborini G, Muratori M, Ng AC, van der Kley F, de Weger A, Schalij MJ, Fusari M, Biglioli P, Bax JJ
Background: This study aimed to evaluate the impact of baseline left ventricular (LV) systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation (TAVI). Survival of patients undergoing TAVI was also compared with that of a population undergoing surgical aortic valve replacement. Methods: One hundred forty-seven consecutive patients (mean age=80±7 years) undergoing TAVI in 2 centers were included. Mean follow-up period was 9.1±5.1 months. Result... Abstract
Cited 28 times since 2010 (2.1 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 90, Issue 6, 1 1 2010, Pages 1922-1929 Mitral valve morphology assessment: three-dimensional transesophageal echocardiography versus computed tomography. Shanks M, Delgado V, Ng AC, van der Kley F, Schuijf JD, Boersma E, van de Veire NR, Nucifora G, Bertini M, de Roos A, Kroft L, Schalij MJ, Bax JJ
Background: Advances in the minimally invasive mitral valve repair techniques increase the demands on accurate and reliable morphologic assessment of the mitral valve using three-dimensional imaging modalities. The present study compared mitral valve geometry measurements obtained by three-dimensional transesophageal echocardiography (TEE) to those obtained with multidetector row computed tomography (MDCT) used as a standard reference. Methods: Clinical preoperative MDCT and intraoperative three... Abstract
Cited 30 times since 2010 (2.2 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 6, Issue 5, 1 1 2010, Pages 643-652 Multimodality imaging in transcatheter aortic valve implantation: key steps to assess procedural feasibility. Delgado V, Ewe SH, Ng AC, van der Kley F, Marsan NA, Schuijf JD, Schalij MJ, Bax JJ
Transcatheter aortic valve implantation (TAVI) has been an important breakthrough in the treatment of patients with symptomatic, severe aortic stenosis and contraindications for surgical aortic valve replacement. Accurate aortic root measurements and evaluation of spatial relationships with the coronary ostia are crucial in pre-operative TAVI assessment. In addition, characterisation of the peripheral artery anatomy and aorta is an important key step in the procedural feasibility evaluation. The... Abstract
Cited 208 times since 2010 (14.6 per year) source: Scopus
European heart journal, Volume 31, Issue 9, 19 3 2010, Pages 1114-1123 Transcatheter aortic valve implantation: role of multi-detector row computed tomography to evaluate prosthesis positioning and deployment in relation to valve function. Delgado V, Ng AC, van de Veire NR, van der Kley F, Schuijf JD, Tops LF, de Weger A, Tavilla G, de Roos A, Kroft LJ, Schalij MJ, Bax JJ
Aims: Aortic regurgitation after transcatheter aortic valve implantation (TAVI) is one of the most frequent complications. However, the underlying mechanisms of this complication remain unclear. The present evaluation studied the anatomic and morphological features of the aortic valve annulus that may predict aortic regurgitation after TAVI. Methods and results: In 53 patients with severe aortic stenosis undergoing TAVI, multi-detector row computed tomography (MDCT) assessment of the aortic valv... Abstract
Cited 14 times since 2010 (1 per year) source: Scopus
JACC. Cardiovascular imaging, Volume 3, Issue 2, 1 1 2010, Pages 222-223 Successful transapical transcatheter valve implantation within a dysfunctional mitral bioprosthesis. de Weger A, Tavilla G, Ng AC, Delgado V, van der Kley F, Schuijf JD, Bax JJ, Klautz RJ
Cited 23 times since 2010 (1.6 per year) source: EuropePMC
The American journal of cardiology, Volume 105, Issue 4, 5 1 2010, Pages 480-486 Assessment with multi-slice computed tomography and gray-scale and virtual histology intravascular ultrasound of gender-specific differences in extent and composition of coronary atherosclerotic plaques in relation to age. Pundziute G, Schuijf JD, van Velzen JE, Jukema JW, van Werkhoven JM, Nucifora G, van der Kley F, Kroft LJ, de Roos A, Boersma E, Reiber JH, Schalij MJ, van der Wall EE, Bax JJ
Data evaluating gender- and age-specific differences in plaque observations on multislice computed tomography (MSCT) are scarce. Accordingly, the aim of this study was to evaluate coronary plaque patterns in men and women in relation to age using MSCT. The findings were compared to observations on grayscale intravascular ultrasound (IVUS) and virtual histology (VH) IVUS. In total, 93 patients (59 men, 34 women) underwent 64-slice MSCT followed by conventional coronary angiography with IVUS. Plaq... Abstract
Cited 24 times since 2010 (1.7 per year) source: EuropePMC
Expert review of cardiovascular therapy, Volume 8, Issue 1, 1 1 2010, Pages 113-123 Transcatheter aortic valve implantation: role of multimodality cardiac imaging. Delgado V, Ng AC, Shanks M, van der Kley F, Schuijf JD, van de Veire NR, Kroft L, de Roos A, Schalij MJ, Bax JJ
Current evidence based on more than 8000 high-risk patients with severe aortic stenosis has demonstrated that transcatheter aortic valve implantation (TAVI) is a feasible alternative to surgical aortic valve replacement in selected patients. Despite current promising results on hemodynamic and clinical improvements, there are several unresolved safety issues, such as the frequency of vascular complications, postprocedural paravalvular leak, atrioventricular heart block and stroke. Multimodality... Abstract
Cited 140 times since 2009 (9.7 per year) source: EuropePMC
European heart journal, Volume 30, Issue 24, 1 1 2009, Pages 3037-3047 Strain analysis in patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing surgical valve replacement. Delgado V, Tops LF, van Bommel RJ, van der Kley F, Marsan NA, Klautz RJ, Versteegh MI, Holman ER, Schalij MJ, Bax JJ
Aims: To evaluate myocardial multidirectional strain and strain rate (S-and-SR) in severe aortic stenosis (AS) patients with preserved left ventricular (LV) ejection fraction (EF), using two-dimensional speckle-tracking strain imaging (2D-STI). The long-term effect of aortic valve replacement (AVR) on S-and-SR was also evaluated. Methods and results: Changes in LV radial, circumferential, and longitudinal S-and-SR were evaluated in 73 severe AS patients (65 +/- 13 years; aortic valve area 0.8 +/... Abstract
Cited 197 times since 2009 (13.6 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 1, 17 3 2009, Pages 94-102 Comparison of aortic root dimensions and geometries before and after transcatheter aortic valve implantation by 2- and 3-dimensional transesophageal echocardiography and multislice computed tomography. Ng AC, Delgado V, van der Kley F, Shanks M, van de Veire NR, Bertini M, Nucifora G, van Bommel RJ, Tops LF, de Weger A, Tavilla G, de Roos A, Kroft LJ, Leung DY, Schuijf J, Schalij MJ, Bax JJ
Background: 3D transesophageal echocardiography (TEE) may provide more accurate aortic annular and left ventricular outflow tract (LVOT) dimensions and geometries compared with 2D TEE. We assessed agreements between 2D and 3D TEE measurements with multislice computed tomography (MSCT) and changes in annular/LVOT areas and geometries after transcatheter aortic valve implantations (TAVI). Methods and results: Two-dimensional circular (pixr(2)), 3D circular, and 3D planimetered annular and LVOT are... Abstract
Cited 4 times since 2009 (0.3 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 5, Issue 5, 1 1 2009, Pages 565-572 Impact of sirolimus-eluting stent implantation compared to bare-metal stent implantation for acute myocardial infarction on coronary plaque composition at nine months follow-up: a Virtual Histology intravascular ultrasound analysis. Results from the Leiden MISSION! intervention study. Atary JZ, Bergheanu SC, van der Hoeven BL, Atsma DE, Bootsma M, van der Kley F, Zeppenfeld K, Jukema JW, Schalij MJ
Aims: To evaluate effects of sirolimus-eluting stents (SES) compared to bare-metal stents (BMS) at stent edges in patients with acute myocardial infarction (AMI). Methods and results: Clinical, angiographic, intravascular ultrasound (lVUS) and virtual histology (VH)-IVUS results were obtained and analysed in 20 SES and 20 BMS AMI patients at the index procedure and at nine months follow-up. Quantitative angiography and IVUS showed a trend toward decreases in mean lumen diameter, vessel volume, m... Abstract