Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
220 results
Cited 4 times since 2021 (1.2 per year) source: EuropePMC
Haematologica, Volume 106, Issue 1, 1 1 2021, Pages 259-263 Macrophage-HFE controls iron metabolism and immune responses in aged mice. Tangudu NK, Yilmaz D, Wörle K, Gruber A, Colucci S, Leopold K, Muckenthaler MU, Vujic Spasic M
Cited 3 times since 2021 (0.9 per year) source: EuropePMC
Bratislavske lekarske listy, Volume 122, Issue 5, 1 1 2021, Pages 357-361 The relationship between neutrophil/lymphocyte ratio and uric acid levels in multiple sclerosis patients. Bolayir A, Cigdem B, Gokce SF, Yilmaz D
Background: In this study, we aimed to determine whether neutrophil / lymphocyte ratio (NLR), obtained by dividing the number of neutrophils by the number of lymphocytes, and uric acid (UA) levels in multiple sclerosis (MS) patients vary compared with healthy controls and to establish correlations among these changes themselves as well as between such changes and MS subtypes, immunomodulatory drug use, the duration of the disease and prognosis. Methods: 150 patients who presented to our hospital... Abstract
Cited 3 times since 2020 (0.9 per year) source: EuropePMC
Cell and tissue research, Volume 383, Issue 3, 28 4 2021, Pages 987-1002 Isthmin1, a secreted signaling protein, acts downstream of diverse embryonic patterning centers in development. Kesavan G, Raible F, Gupta M, Machate A, Yilmaz D, Brand M
Extracellular signals play essential roles during embryonic patterning by providing positional information in a concentration-dependent manner, and many such signals, like Wnt, fibroblast growth factor (FGF), Hedgehog (Hh), and retinoic acid, act by being secreted into the extracellular space, thereby triggering receptor-mediated responses in other cells. Isthmin1 (ism1) is a secreted protein whose gene expression pattern coincides with that of early dorsal determinants, nodal ligand genes like... Abstract
Cited 2 times since 2020 (0.6 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 44, Issue 1, 12 2 2020, Pages 120-128 Mechanical extraction of cardiac implantable electronic devices leads with long dwell time: Efficacy and safety of the step up approach. Lensvelt LMH, Egorova AD, Schalij MJ, Yilmaz D, Kennergren C, Bootsma M, van Erven L
The aim of this study was to evaluate the efficacy and safety of the stepwise mechanical transvenous lead extraction approach in a patient population with chronically implanted transvenous leads with a long dwell time. From January 2014 till December 2018, all lead extractions with lead dwell time ≥5 years performed at our tertiary centre were retrospectively analysed. A total of 173 leads, from 78 patients (median age 68 years; 81% male) with a median dwell time of 9 years (interquartile range... Abstract
Cited 1 times since 2020 (0.3 per year) source: EuropePMC
Journal of pediatric hematology/oncology, Volume 42, Issue 8, 1 1 2020, Pages e712-e717 High-mobility Group Box 1 Protein in Pediatric Trauma Patients With Acute Traumatic Coagulopathy or Disseminated Intravascular Coagulation. Ulusoy E, Duman M, Çağlar A, Küme T, Er A, Akgül F, Çitlenbik H, Yilmaz D, Ören H
Objectives: Trauma can induce the release of high-mobility group box 1 (HMGB1), which plays an important role in the activation of coagulation. In this study, we aimed to evaluate the role of HMGB1 in the early diagnosis of acute traumatic coagulopathy (ATC), disseminated intravascular coagulation, and clinical course. Materials and methods: One hundred pediatric trauma patients and 50 healthy controls were enrolled. Demographic data, physical examination results, trauma scores, International So... Abstract
Cited 4 times since 2020 (1.1 per year) source: EuropePMC
Journal of gastrointestinal and liver diseases : JGLD, Volume 29, Issue 4, 27 4 2020, Pages 617-622 Evaluation of the Association between Programmed Cell Death-1 Gene Polymorphisms and Hepatocellular Carcinoma Susceptibility in Turkish Subjects. A Pilot Study. Demirci AF, Demirtas CO, Eren F, Yilmaz D, Keklikkiran C, Ozdogan OC, Gunduz F
Background and aims: Programmed cell death-1 (PD-1) has a vital role in regulating T-cell function, and immune escape mechanism of cancer cells. It was shown that there could be a relationship between single nucleotide polymorphisms (SNPs) in the PD-1 gene and susceptibility to hepatocellular carcinoma (HCC) based on various studies. We aimed to investigate the role of three SNPs within the PD-1 gene in susceptibility to HCC in the Turkish population. Methods: Single nucleotide polymorphisms of... Abstract
Nature communications, Volume 11, Issue 1, 8 2 2020, Pages 5141 Author Correction: Straightforward preparation of supramolecular Janus nanorods by hydrogen bonding of end-functionalized polymers. Han S, Pensec S, Yilmaz D, Lorthioir C, Jestin J, Guigner JM, Niepceron F, Rieger J, Stoffelbach F, Nicol E, Colombani O, Bouteiller L
An amendment to this paper has been published and can be accessed via a link at the top of the paper. Abstract
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
Nature communications, Volume 11, Issue 1, 21 3 2020, Pages 4760 Straightforward preparation of supramolecular Janus nanorods by hydrogen bonding of end-functionalized polymers. Han S, Pensec S, Yilmaz D, Lorthioir C, Jestin J, Guigner JM, Niepceron F, Rieger J, Stoffelbach F, Nicol E, Colombani O, Bouteiller L
Janus cylinders are one-dimensional colloids that have two faces with different compositions and functionalities, and are useful as building blocks for advanced functional materials. Such anisotropic objects are difficult to prepare with nanometric dimensions. Here we describe a robust and versatile strategy to form micrometer long Janus nanorods with diameters in the 10-nanometer range, by self-assembly in water of end-functionalized polymers. The Janus topology is not a result of the phase seg... Abstract
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
Annals of vascular surgery, Volume 68, 2 1 2020, Pages 159-165 Identifying Factors Influencing Decision Making in Patients Diagnosed with Carotid Body Tumors: An Exploratory Study. Alimohamad H, Yilmaz D, Hamming JF, Schepers A
Background: Carotid body tumors (CBTs) are rare highly vascularized and slow enlarging tumors arising from the paraganglionic tissue at the carotid bifurcation. Main treatment options for CBTs are surgical resection or "wait and scan" strategy. The choice for either strategy may be equally good medically in many patients. A structured "shared decision making" (SDM) might be helpful for guiding patients. Objectives: To develop an SDM strategy for the surgical treatment, we aim... Abstract
Cited 15 times since 2020 (3.7 per year) source: EuropePMC
Heart rhythm O2, Volume 1, Issue 1, 27 4 2020, Pages 3-9 Atrial fibrillation detection from raw photoplethysmography waveforms: A deep learning application. Aschbacher K, Yilmaz D, Kerem Y, Crawford S, Benaron D, Liu J, Eaton M, Tison GH, Olgin JE, Li Y, Marcus GM
Background: Atrial fibrillation (AF), a common cause of stroke, often is asymptomatic. Smartphones and smartwatches can detect AF using heart rate patterns inferred using photoplethysmography (PPG); however, enhanced accuracy is required to reduce false positives in screening populations. Objective: The purpose of this study was to test the hypothesis that a deep learning algorithm given raw, smartwatch-derived PPG waveforms would discriminate AF from normal sinus rhythm better than algorithms u... Abstract
Cited 7 times since 2020 (1.7 per year) source: EuropePMC
Japan journal of nursing science : JJNS, Volume 17, Issue 4, 2 1 2020, Pages e12338 Effects of three different methods used during heel lance procedures on pain level in term neonates. Yilmaz D, Inal S
Aim: This study aims to experimentally determine effects of three different methods (swaddling; swaddling and holding; swaddling, holding and breastfeeding) used during heel lancing on pain levels in healthy term neonates. Methods: This study was a prospective, randomized controlled trial. The sample of newborns (n = 160) were allocated to the groups (group 1, control; group 2, swaddling; group 3, swaddling and holding; group 4, swaddling, holding and breastfeeding) by blocked randomization. The... Abstract
Cited 3 times since 2020 (0.7 per year) source: EuropePMC
Medicine, Volume 99, Issue 17, 1 1 2020, Pages e19851 Pain acceptance levels of patients with chronic pain. Çinar HG, Yilmaz D, Akin E
This study was conducted with the aim of determining pain acceptance levels in patients with chronic pain attending an algology outpatients' department.The research was conducted as a descriptive and cross-sectional study. The population of the study consisted of 97 patients with chronic pain who attended the Algology Outpatients' Department of the Health Implementation and Research Center of Bursa Uludağ University. A Patient Description Form and a Chronic Pain Acceptance Questionnair... Abstract
Cited 18 times since 2020 (4.3 per year) source: EuropePMC
Current opinion in cell biology, Volume 64, 26 4 2020, Pages 58-66 How to maintain the genome in nuclear space. Mitrentsi I, Yilmaz D, Soutoglou E
Genomic instability can be life-threatening. The fine balance between error-free and mutagenic DNA repair pathways is essential for maintaining genome integrity. Recent advances in DNA double-strand break induction and detection techniques have allowed the investigation of DNA damage and repair in the context of the highly complex nuclear structure. These studies have revealed that the 3D genome folding, nuclear compartmentalization and cytoskeletal components control the spatial distribution of... Abstract
Cited 7 times since 2020 (1.7 per year) source: EuropePMC
Oral surgery, oral medicine, oral pathology and oral radiology, Volume 130, Issue 2, 18 3 2020, Pages 209-216 Evaluation of a metal artifact reduction algorithm and an optimization filter in the estimation of peri-implant dehiscence defects by using cone beam computed tomography: an in-vitro study. Bayrak S, Orhan K, Kursun Çakmak ES, Görürgöz C, Odabaşı O, Yilmaz D, Atakan C
Objectives: The aim of this study was to assess the effect of a metal artifact reduction (MAR) algorithm and the adaptive image noise optimizer (AINO) optimization filter in the detection of peri-implant dehiscences with cone beam computed tomography (CBCT). Study design: Nine implants (3 zirconium, 3 titanium, and 3 zirconium-titanium) were placed in 3 sheep heads. Dehiscences were created on the buccal and lingual/palatal surfaces. A total of 9 defects and 9 controls with no defects were evalu... Abstract
Cited 1 times since 2020 (0.2 per year) source: EuropePMC
Talanta, Volume 214, 12 2 2020, Pages 120828 Monitoring forced degradation of drugs using silica coated AgNPs with surface-enhanced Raman scattering. Yilmaz H, Cobandede Z, Yilmaz D, Cinkilic A, Culha M, Demiralay EC
Potential degradation products (DPs), even in small concentrations, can cause changes in pharmacological and toxicological properties of a drug with a significant impact on product quality and safety. Thus, their stability and understanding of possible degradation mechanisms have a significant importance. Although liquid chromatography is the conventional technique used for forced degradation studies with excellent accuracy and reproducibility, the main disadvantages of the technique are being e... Abstract
Cited 11 times since 2020 (2.5 per year) source: EuropePMC
Acta odontologica Scandinavica, Volume 78, Issue 5, 24 4 2020, Pages 327-331 Salivary human beta-defensins and cathelicidin levels in relation to periodontitis and type 2 diabetes mellitus. Yilmaz D, Topcu AO, Akcay EU, Altındis M, Gursoy UK
Objective: Type 2 diabetes mellitus (T2DM) is a well-defined risk factor of periodontitis and it can affect expression of human beta-defensins (hBDs) and cathelicidin (LL-37) as well. The aim of the present study was to evaluate the impact of periodontitis and T2DM on salivary concentrations of these antimicrobial peptides.Material and methods: Unstimulated saliva samples, together with full-mouth periodontal recordings were collected from 92 individuals with periodontitis (63 with T2DM and 21 s... Abstract
Cited 13 times since 2020 (3 per year) source: EuropePMC
Biotechnology progress, Volume 36, Issue 3, 9 2 2020, Pages e2947 Application of Raman spectroscopy in monoclonal antibody producing continuous systems for downstream process intensification. Yilmaz D, Mehdizadeh H, Navarro D, Shehzad A, O'Connor M, McCormick P
Monoclonal antibodies (mAbs) are biopharmaceuticals produced by mammalian cell lines in bioreactors at a variety of scales. Cell engineering, media optimization, process monitoring, and control strategies for in vitro production have become crucial subjects to meet increasing demand for these high value pharmaceuticals. Raman Spectroscopy has gained great attention in the pharmaceutical industry for process monitoring and control to maintain quality assurance. For the first time, this article de... Abstract
Cited 11 times since 2019 (2.4 per year) source: EuropePMC
Brain research, Volume 1726, 16 3 2019, Pages 146510 Artificial Intelligence and the detection of pediatric concussion using epigenomic analysis. Bahado-Singh RO, Vishweswaraiah S, Er A, Aydas B, Turkoglu O, Taskin BD, Duman M, Yilmaz D, Radhakrishna U
Concussion, also referred to as mild traumatic brain injury (mTBI) is the most common type of traumatic brain injury. Currently concussion is an area ofintensescientific interest to better understand the biological mechanisms and for biomarker development. We evaluated whole genome-wide blood DNA cytosine ('CpG') methylation in 17 pediatric concussion isolated cases and 18 unaffected controls using Illumina Infinium MethylationEPIC assay. Pathway analysis was performed using Ingenuity... Abstract
Cited 6 times since 2019 (1.2 per year) source: EuropePMC
JBMR plus, Volume 3, Issue 9, 26 4 2019, Pages e10206 Despite Genetic Iron Overload, <i>Hfe</i>-Hemochromatosis Mice Do Not Show Bone Loss. Wagner A, Alan B, Yilmaz D, Ahmad M, Liu P, Tangudu NK, Tuckermann JP, Vujic Spasic M
One of the most prevalent genetic iron overload disorders in Caucasians is caused by mutations in the HFE gene. Both HFE patients and Hfe-mouse models develop a progressive accumulation of iron in the parenchymal cells of various tissues, eventually resulting in liver cirrhosis, hepatocellular carcinoma, cardiomyopathies, hypogonadism, and other pathologies. Clinical data and preclinical models have brought considerable attention to the correlation between iron overload and the development of os... Abstract
Cited 5 times since 2018 (0.9 per year) source: EuropePMC
Journal of periodontal research, Volume 53, Issue 5, 4 1 2018, Pages 916-923 Matrix metalloproteinase-7 in periodontitis with type 2 diabetes mellitus. Zeidán-Chuliá F, Yilmaz D, Häkkinen L, Könönen E, Neves de Oliveira BH, Güncü G, Uitto VJ, Caglayan F, Gürsoy UK
Background and objective: Elevated levels of matrix metalloproteinase-7 (MMP7) have been observed in serum samples of subjects with type 2 diabetes mellitus (T2DM) and in gingival tissues of subjects with periodontitis. The aim of the present study was to collect in vivo and in silico evidence on the role of MMP7 in the interplay between T2DM and generalized periodontitis (GP). Material and methods: The extent of MMP7 expression and localization were immunohistochemically analyzed in gingival ti... Abstract