Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
482 results
Cited 50 times since 2011 (4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 58, Issue 18, 6 1 2011, Pages 1910-1918 Hemodynamic and clinical impact of prosthesis-patient mismatch after transcatheter aortic valve implantation. Ewe SH, Muratori M, Delgado V, Pepi M, Tamborini G, Fusini L, Klautz RJ, Gripari P, Bax JJ, Fusari M, Schalij MJ, Marsan NA
Objectives: This study examined the mid-term hemodynamic and clinical impact of prosthesis-patient mismatch (PPM) in patients undergoing transcatheter aortic valve implantation (TAVI) with balloon-expandable valves. Background: PPM can be observed after aortic valve surgery. However, little is known about the incidence of PPM in patients undergoing TAVI. Methods: Echocardiography and clinical assessment were performed in 165 patients at baseline, before hospital discharge, and at 6 months after... Abstract
Cited 15 times since 2011 (1.2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 97, Issue 20, 1 1 2011, Pages 1704-1714 Multimodality imaging before, during, and after percutaneous mitral valve repair. Delgado V, Kapadia S, Marsan NA, Schalij MJ, Tuzcu EM, Bax JJ
Cited 16 times since 2011 (1.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 98, Issue 3, 13 2 2011, Pages 232-237 Age- and gender-specific differences in the prognostic value of CT coronary angiography. Yiu KH, de Graaf FR, Schuijf JD, van Werkhoven JM, Marsan NA, Veltman CE, de Roos A, Pazhenkottil A, Kroft LJ, Boersma E, Herzog B, Leung M, Maffei E, Leung DY, Kaufmann PA, Cademartiri F, Bax JJ, Jukema JW
Objective: To evaluate the potential age- and gender-specific differences in the incidence and prognostic value of coronary artery disease (CAD) in patients undergoing CT coronary angiography (CTA). Design and patients: In this multicentre prospective registry study, 2432 patients (mean age 57 ± 12, 56% male) underwent CTA for suspected CAD. Patients were stratified into four groups according to age Abstract
Cited 13 times since 2011 (1 per year) source: EuropePMC
European journal of heart failure, Volume 13, Issue 10, 25 4 2011, Pages 1133-1139 The effect of cardiac resynchronization therapy on left ventricular diastolic function assessed with speckle-tracking echocardiography. Shanks M, Antoni ML, Hoke U, Bertini M, Ng AC, Auger D, Marsan NA, van Erven L, Holman ER, Schalij MJ, Bax JJ, Delgado V
Aims: Changes in left ventricular (LV) diastolic function after cardiac resynchronization therapy (CRT) in relation to LV reverse remodelling and heart failure aetiology have not been extensively characterized. The aims of the study were to evaluate changes in LV diastolic function with speckle-tracking echocardiography in relation to: (i) cardiac resynchronization therapy response (LV remodelling) and (ii) heart failure aetiology. Methods and results: A total of 192 heart failure patients under... Abstract
Cited 172 times since 2011 (13.5 per year) source: Scopus
The American journal of cardiology, Volume 108, Issue 10, 17 3 2011, Pages 1470-1477 Location and severity of aortic valve calcium and implications for aortic regurgitation after transcatheter aortic valve implantation. Ewe SH, Ng AC, Schuijf JD, van der Kley F, Colli A, Palmen M, de Weger A, Marsan NA, Holman ER, de Roos A, Schalij MJ, Bax JJ, Delgado V
Location of aortic valve calcium (AVC) can be better visualized on contrast-enhanced multidetector row computed tomography. The present evaluation examined whether AVC severity and its location could influence paravalvular aortic regurgitation (AR) after transcatheter aortic valve implantation. A total of 79 patients (age 80 ± 7 years, 49% men) with preprocedural multidetector row computed tomography were included. Volumetric AVC quantification and its location were assessed. Transesophageal ech... Abstract
Cited 5 times since 2011 (0.4 per year) source: EuropePMC
European journal of heart failure, Volume 13, Issue 11, 16 3 2011, Pages 1202-1210 Myocardial collagen turnover after surgical ventricular restoration in heart failure patients. ten Brinke EA, Witkowski TG, Delgado V, Klein P, Klok M, Marsan NA, Klautz RJ, van der Wall EE, Bax JJ, van der Laarse A, Steendijk P
Aims: Surgical ventricular restoration (SVR) aims to normalize left ventricular (LV) volume and shape in patients with ischaemic cardiomyopathy and anterior wall scar. The chronic effects on LV function may depend on alterations in myocardial collagen metabolism. The present study evaluated myocardial collagen synthesis and degradation rates at baseline and at 6 months follow-up after SVR. We hypothesize that the chronic effects of SVR on LV function and clinical outcome depend on alterations in... Abstract
Cited 24 times since 2011 (1.9 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 24, Issue 10, 6 1 2011, Pages 1126-1133 Comprehensive assessment of changes in left atrial volumes and function after ST-segment elevation acute myocardial infarction: role of two-dimensional speckle-tracking strain imaging. Antoni ML, Ten Brinke EA, Marsan NA, Atary JZ, Holman ER, van der Wall EE, Schalij MJ, Bax JJ, Delgado V
Background: Left atrial (LA) size has been associated with adverse outcome in patients after acute myocardial infarction. However, data about the occurrence of late LA enlargement and changes in LA function during follow-up are scarce. The purpose of the current study was to evaluate changes in LA size and function during 1-year follow-up. Methods: The study population comprised 407 patients with acute myocardial infarction who were treated with primary percutaneous coronary intervention. At bas... Abstract
Cited 89 times since 2011 (7 per year) source: EuropePMC
Circulation, Volume 124, Issue 8, 1 1 2011, Pages 912-919 Cardiac resynchronization therapy as a therapeutic option in patients with moderate-severe functional mitral regurgitation and high operative risk. van Bommel RJ, Marsan NA, Delgado V, Borleffs CJ, van Rijnsoever EP, Schalij MJ, Bax JJ
Background: Functional mitral regurgitation (MR) is a common finding in heart failure patients with dilated cardiomyopathy and has important prognostic implications. However, the increased operative risk of these patients may result in low referral or high denial rate for mitral valve surgery. Cardiac resynchronization therapy (CRT) has been shown to have a favorable effect on MR. Aims of this study were to (1) evaluate CRT as a therapeutic option in heart failure patients with functional MR and... Abstract
Cited 12 times since 2011 (0.9 per year) source: EuropePMC
The American journal of cardiology, Volume 108, Issue 5, 28 4 2011, Pages 711-717 Prediction of response to cardiac resynchronization therapy combining two different three-dimensional analyses of left ventricular dyssynchrony. Auger D, Bertini M, Marsan NA, Hoke U, Ewe SH, Thijssen J, Witkowski TG, Yiu KH, Ng AC, van der Wall EE, Schalij MJ, Bax JJ, Delgado V
Triplane tissue synchronization imaging (TSI) and real-time 3-dimensional echocardiography (RT3DE) provide different characterizations of left ventricular (LV) mechanics and dyssynchrony. Triplane TSI assesses differences in time to peak systolic segmental myocardial tissue velocities, whereas RT3DE evaluates differences in time to minimum end-systolic regional volumes. Whether an approach using the 2 3D techniques predicts better significant reverse remodeling after cardiac resynchronization th... Abstract
Cited 43 times since 2011 (3.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 97, Issue 16, 25 4 2011, Pages 1332-1337 Left atrial strain is related to adverse events in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Antoni ML, ten Brinke EA, Atary JZ, Marsan NA, Holman ER, Schalij MJ, Bax JJ, Delgado V
Background: Left atrial (LA) maximal volume is of prognostic value in patients after acute myocardial infarction (AMI). Recently, LA mechanical function and LA strain have been introduced as alternative methods to assess LA performance more accurately. Objective: To evaluate the relation between LA volume, mechanical function and strain, and adverse events in patients after AMI. Methods: Patients with AMI underwent two-dimensional echocardiography within 48 h of admission. LA volume and LA perfo... Abstract
Cited 18 times since 2011 (1.4 per year) source: EuropePMC
American heart journal, Volume 161, Issue 6, 11 2 2011, Pages 1060-1066 Site of latest activation in patients eligible for cardiac resynchronization therapy: patterns of dyssynchrony among different QRS configurations and impact of heart failure etiology. van Bommel RJ, Ypenburg C, Mollema SA, Borleffs CJ, Delgado V, Bertini M, Marsan NA, van der Wall EE, Schalij MJ, Bax JJ
Introduction: Cardiac resynchronization therapy (CRT) has emerged as a treatment option for patients with end-stage heart failure and a QRS duration ≥120 ms. Nonetheless, many patients with a prolonged QRS do not demonstrate left ventricular (LV) mechanical dyssynchrony, and discrepancies between electrical and mechanical dyssynchrony have been observed. In addition, several studies demonstrated that superior benefits after CRT could be achieved when the LV pacing lead was positioned at the most... Abstract
Cited 28 times since 2011 (2.1 per year) source: EuropePMC
The American journal of cardiology, Volume 108, Issue 1, 27 4 2011, Pages 63-68 Comparison of long-term survival of men versus women with heart failure treated with cardiac resynchronization therapy. Mooyaart EA, Marsan NA, van Bommel RJ, Thijssen J, Borleffs CJ, Delgado V, van der Wall EE, Schalij MJ, Bax JJ
Cardiac resynchronization therapy (CRT) is an established treatment of patients with heart failure. Several baseline characteristics can influence the CRT outcomes, and little is known about the effect of gender. The aim of the present study was to elucidate the gender-related differences in long-term survival after CRT. A total of 578 consecutive patients with heart failure underwent CRT. At baseline and 6 months after CRT, the clinical and echocardiographic parameters were obtained. All-cause... Abstract
Cited 70 times since 2011 (5.3 per year) source: Scopus
The Annals of thoracic surgery, Volume 92, Issue 4, 21 3 2011, Pages 1244-1251 Outcomes after transcatheter aortic valve implantation: transfemoral versus transapical approach. Ewe SH, Delgado V, Ng AC, Antoni ML, van der Kley F, Marsan NA, de Weger A, Tavilla G, Holman ER, Schalij MJ, Bax JJ
Background: Transcatheter aortic valve implantation is commonly implanted through a transfemoral (TFA) or transapical approach (TAA) for patients with severe aortic stenosis. This study aimed to describe the clinical and echocardiographic outcomes of TFA versus TAA. Methods: Clinical and echocardiographic evaluations were performed at baseline, post-TAVI (transcatheter aortic valve implantation), at 6 and 12 months follow-up in 107 consecutive patients who underwent TAVI with balloon-expandable... Abstract
Cited 25 times since 2011 (1.9 per year) source: EuropePMC
Thyroid : official journal of the American Thyroid Association, Volume 21, Issue 5, 21 3 2011, Pages 471-476 Both exogenous subclinical hyperthyroidism and short-term overt hypothyroidism affect myocardial strain in patients with differentiated thyroid carcinoma. Abdulrahman RM, Delgado V, Hoftijzer HC, Ng AC, Ewe SH, Marsan NA, Holman ER, Hovens GC, Corssmit EP, Romijn JA, Bax JJ, Smit JW
Background: The cardiovascular effects of transitions from exogenous subclinical hyperthyroidism to short-term overt hypothyroidism in patients treated for differentiated thyroid carcinoma remain unclear. The present study aims at evaluating the changes in multidirectional myocardial strain using two-dimensional (2D) speckle tracking during this controlled transition from exogenous subclinical hyperthyroidism to overt hypothyroidism. Methods: The study included 14 patients with differentiated th... Abstract
Cited 40 times since 2011 (3 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 24, Issue 4, 24 4 2011, Pages 405-413 Quantitative analysis of mitral valve apparatus in mitral valve prolapse before and after annuloplasty: a three-dimensional intraoperative transesophageal study. Maffessanti F, Marsan NA, Tamborini G, Sugeng L, Caiani EG, Gripari P, Alamanni F, Jeevanandam V, Lang RM, Pepi M
Background: Intraoperative real-time three-dimensional transesophageal echocardiography has been shown useful in the evaluation of the mitral valve (MV) apparatus, and dedicated commercial software allows its quantitative assessment. The aims of this study were to (1) quantify the effects induced by prolapse on MV anatomy in the presence of fibroelastic deficiency (FED) or Barlow's disease (BD), (2) assess the effect of surgery on the MV apparatus, and (3) investigate the potential role of... Abstract
Cited 28 times since 2011 (2.1 per year) source: EuropePMC
American heart journal, Volume 161, Issue 2, 1 1 2011, Pages 314-321 Left atrial reverse remodeling and functional improvement after mitral valve repair in degenerative mitral regurgitation: a real-time 3-dimensional echocardiography study. Marsan NA, Maffessanti F, Tamborini G, Gripari P, Caiani E, Fusini L, Muratori M, Zanobini M, Alamanni F, Pepi M
Background: Severe mitral regurgitation is often associated with left atrium (LA) enlargement, which is a well-known predictor of adverse cardiovascular outcomes. However, only few data are available on the effect of mitral valve (MV) repair on LA size. The aim of this study was to evaluate, using real-time 3-dimensional echocardiography, the changes in LA volumes after MV repair. Methods: A total of 65 patients with severe mitral regurgitation due to MV prolapse and scheduled for repair at an e... Abstract
Cited 19 times since 2011 (1.4 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 91, Issue 2, 1 1 2011, Pages 491-498 Surgical ventricular restoration for patients with ischemic heart failure: determinants of two-year survival. Witkowski TG, ten Brinke EA, Delgado V, Ng AC, Bertini M, Marsan NA, Ewe SH, Auger D, Yiu KH, Braun J, Klein P, Steendijk P, Versteegh MI, Klautz RJ, Bax JJ
Background: Surgical ventricular restoration (SVR) improves left ventricular (LV) systolic function by partially restoring the normal geometry of the left ventricle. However, the beneficial effects of this surgical procedure on long-term clinical outcome remain controversial. The present study aimed to evaluate the independent determinants of 2-year morbidity and mortality rates after SVR. Methods: Seventy-nine patients with ischemic heart disease and LV ejection fraction of 0.35 or less were in... Abstract
Cited 32 times since 2011 (2.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 57, Issue 5, 1 1 2011, Pages 549-555 Impaired renal function is associated with echocardiographic nonresponse and poor prognosis after cardiac resynchronization therapy. Van Bommel RJ, Mollema SA, Borleffs CJ, Bertini M, Ypenburg C, Marsan NA, Delgado V, Van Der Wall EE, Schalij MJ, Bax JJ
Objectives: Aims of this study were to investigate the effect of renal function on left ventricular (LV) reverse remodeling and long-term outcome after cardiac resynchronization therapy (CRT), and to explore the relation between LV reverse remodeling and changes in renal function at 6-month follow-up. Background: Renal insufficiency is highly prevalent in heart failure patients, including patients eligible for CRT, and is associated with poor prognosis. Methods: The study comprised 490 patients... Abstract
Cited 31 times since 2011 (2.3 per year) source: EuropePMC
Journal of magnetic resonance imaging : JMRI, Volume 33, Issue 2, 1 1 2011, Pages 312-319 Left ventricular diastolic function assessment from three-dimensional three-directional velocity-encoded MRI with retrospective valve tracking. Brandts A, Bertini M, van Dijk EJ, Delgado V, Marsan NA, van der Geest RJ, Siebelink HM, de Roos A, Bax JJ, Westenberg JJ
Purpose: To compare parameters describing left ventricular (LV) diastolic function obtained with three-dimensional (3D) three-directional velocity-encoded (VE) MRI with retrospective valve tracking and two-dimensional (2D) one-directional VE MRI in patients with ischemic heart failure. Second, to compare classification of LV diastolic function, and in particular for discriminating restrictive filling patterns, with both MRI techniques versus Doppler echocardiography. Materials and methods: The 3... Abstract
Cited 21 times since 2011 (1.6 per year) source: EuropePMC
American heart journal, Volume 161, Issue 3, 31 5 2011, Pages 552-557 Clinical and echocardiographic predictors of nonresponse to cardiac resynchronization therapy. Shanks M, Delgado V, Ng AC, Auger D, Mooyaart EA, Bertini M, Marsan NA, van Bommel RJ, Holman ER, Poldermans D, Schalij MJ, Bax JJ
Background: Lack of response to cardiac resynchronization therapy (CRT) ranges between 30% to 40% of heart failure (HF) patients. The present study aimed to evaluate the clinical and echocardiographic determinants of nonresponse to CRT. Methods: A total of 581 patients (66.4 ± 10.0 years, 77.9% male) with advanced HF scheduled for CRT implantation were included. Clinical and echocardiographic evaluations were performed at baseline and 6 months of follow-up. Nonresponse was defined as no improvem... Abstract