Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
486 results
Cited 3 times since 2016 (0.4 per year) source: EuropePMC
Current opinion in cardiology, Volume 31, Issue 5, 1 1 2016, Pages 523-530 Mechanical dyssynchrony in patients with heart failure and reduced ejection fraction: how to measure? Khidir MJ, Delgado V, Ajmone Marsan N, Bax JJ
Purpose of review: This article summarizes the most recent imaging techniques to assess left ventricular mechanical dyssynchrony and discusses their value to predict response to cardiac resynchronization therapy (CRT) together with assessment of myocardial scar and cardiac venous anatomy. Recent findings: Left ventricular mechanical dyssynchrony has been associated with prognosis of heart failure patients and has been shown to influence the efficacy of CRT. Although current guidelines do not rec... Abstract
Cited 12 times since 2016 (1.5 per year) source: EuropePMC
The American journal of cardiology, Volume 118, Issue 10, 23 4 2016, Pages 1533-1538 Comparison of Quantity of Calcific Deposits by Multidetector Computed Tomography in the Aortic Valve and Coronary Arteries. van Rosendael PJ, Kamperidis V, Kong WK, van Rosendael AR, Marsan NA, Bax JJ, Delgado V
The aim of this study was to compare the calcium burden of the aortic valve and coronary arteries with multidetector computed tomography (MDCT) in a propensity score-matched population of patients with a bicuspid versus a tricuspid aortic valve. From an ongoing clinical registry of patients who underwent MDCT, 70 patients with bicuspid aortic valve and 210 patients with tricuspid aortic valve were matched based on age, gender, cardiovascular risk factors, chest pain symptoms, and MDCT indication... Abstract
Cited 17 times since 2016 (2.2 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 102, Issue 6, 22 4 2016, Pages 1981-1987 Effect of Aortic Valve Replacement on Aortic Root Dilatation Rate in Patients With Bicuspid and Tricuspid Aortic Valves. Regeer MV, Versteegh MI, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Background: It remains unclear whether aortic valve replacement (AVR) has an effect on the aortic root dilatation rate in patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV). The present study evaluated the pre- and postoperative annual aortic root dilatation rates in BAV and TAV. Methods: A total of 93 patients (67 ± 11 years; 71% men) who underwent AVR between 2003 and 2013 and had at least 2 pre- and postoperative echocardiographic studies 1 year or more apart were incl... Abstract
Cited 12 times since 2016 (1.5 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 29, Issue 9, 19 3 2016, Pages 871-878 Prevalence and Correlates of Early Right Ventricular Dysfunction in Sarcoidosis and Its Association with Outcome. Joyce E, Kamperidis V, Ninaber MK, Katsanos S, Debonnaire P, Schalij MJ, Taube C, Bax JJ, Delgado V, Ajmone Marsan N
Background: Right ventricular (RV) function has not been systematically assessed in sarcoidosis. The aim of this study was to assess the prevalence and associates of RV dysfunction in sarcoidosis using global longitudinal peak systolic strain (GLS). Furthermore, whether RV dysfunction was associated with clinical outcomes was investigated. Methods: A total of 88 patients with sarcoidosis (mean age, 54 ± 13 years; 51% men) without known sarcoid-related or other structural heart disease or alterna... Abstract
Cited 9 times since 2016 (1.1 per year) source: EuropePMC
Echocardiography (Mount Kisco, N.Y.), Volume 33, Issue 10, 25 4 2016, Pages 1458-1464 Left ventricular reverse remodeling after aortic valve surgery for acute versus chronic aortic regurgitation. Regeer MV, Versteegh MI, Ajmone Marsan N, Schalij MJ, Klautz RJ, Bax JJ, Delgado V
Aims: Extent of left ventricular (LV) reverse remodeling after aortic valve repair or replacement (AVR) may differ between patients operated for acute aortic regurgitation (AR) and chronic AR. The aim of this study was to compare changes in LV volumes and function between patients with acute and chronic AR who underwent AVR. Methods and results: A total of 98 patients (54±15 years, 61% men) with acute (n=21) or chronic AR (n=77) were included in the present retrospective evaluation. LV volumes,... Abstract
Cited 1 times since 2016 (0.1 per year) source: EuropePMC
Echocardiography (Mount Kisco, N.Y.), Volume 33, Issue 10, 16 3 2016, Pages 1532-1538 Assessment of global left ventricular excursion using three-dimensional dobutamine stress echocardiography to identify significant coronary artery disease. Hoogslag GE, Joyce E, Bax JJ, Ajmone Marsan N, Delgado V
Background: Quantitative three-dimensional (3D) dobutamine stress echocardiography (DSE) for myocardial ischemia detection may be an adjuvant to left ventricular (LV) wall-motion analysis. The aim of the current study was to assess the association between global 3D LV excursion during DSE and the presence of significant coronary artery disease (CAD) on coronary angiography. Methods: Three-dimensional DSE was performed in 40 patients (67±12 years, 68% male) who underwent subsequent coronary angio... Abstract
Cited 11 times since 2016 (1.4 per year) source: Scopus
The American journal of cardiology, Volume 118, Issue 4, 29 5 2016, Pages 567-571 Impact of Different Iterations of Devices and Degree of Aortic Valve Calcium on Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation. Kong WK, van Rosendael PJ, van der Kley F, de Weger A, Kamperidis V, Regeer MV, Marsan NA, Bax JJ, Delgado V
The iterations of the SAPIEN prosthesis might impact the incidence and grade of paravalvular regurgitation (PVR). The aim of this study was to assess the impact of iterations of balloon-expandable valves (SAPIEN, SAPIEN XT, and SAPIEN 3) and degree of aortic valve calcification (AVC) on the severity of PVR after transcatheter aortic valve implantation (TAVI). Comprehensive echocardiographic examinations and multidetector computed tomography (MDCT) were performed in 272 patients (127 men, 81 ± 7 ... Abstract
Cited 4 times since 2016 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 118, Issue 3, 14 2 2016, Pages 326-331 Prognostic Implications of Elevated Pulmonary Artery Pressure After ST-Segment Elevation Myocardial Infarction. Haeck ML, Hoogslag GE, Boden H, Velders MA, Katsanos S, Al Amri I, Debonnaire P, Schalij MJ, Vliegen HW, Bax JJ, Marsan NA, Delgado V
Elevated systolic pulmonary artery pressure (SPAP) after ST-segment elevation myocardial infarction (STEMI) has been associated with adverse outcome. However, little is known about the development of increased SPAP after STEMI treated with primary percutaneous coronary intervention. The aims of this study were to investigate the incidence and determinants of elevated SPAP (SPAP ≥36 mm Hg at 12 months) after first STEMI and to analyze its prognostic implications. A total of 705 patients (60 ± 12 ... Abstract
Cited 2 times since 2016 (0.2 per year) source: EuropePMC
American heart journal, Volume 178, 30 5 2016, Pages 115-125 Time course, predictors, and prognostic implications of significant mitral regurgitation after ST-segment elevation myocardial infarction. Abate E, Hoogslag GE, Al Amri I, Debonnaire P, Wolterbeek R, Bax JJ, Delgado V, Marsan NA
Background: Ischemic mitral regurgitation (MR) is a known complication of ST-segment elevation myocardial infarction (STEMI) with important prognostic implications. We evaluated changes over time in ischemic MR after STEMI and the prevalence and predictors of significant (grade ≥2) MR at 12 months. Furthermore, the prognostic additional value of significant MR at 12-month follow-up over acute MR was assessed. Methods: STEMI patients (n = 1,599; 77% male; 60 ± 12 years) treated with primary percu... Abstract
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 11, Issue 13, 1 1 2016, Pages 1554-1561 Acute effect of MitraClip implantation on mitral valve geometry in patients with functional mitral regurgitation: insights from three-dimensional transoesophageal echocardiography. Al Amri I, Debonnaire P, van der Kley F, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Aims: Our aim was to evaluate the acute effects of transcatheter edge-to-edge mitral valve repair using the MitraClip device on mitral valve geometry in patients with functional mitral regurgitation (FMR). Methods and results: Forty-two patients (age 73 years [IQ range 66.1-78.0], 55% men, 62% ischaemic FMR) with moderate-to-severe and severe FMR treated with the MitraClip were included. Three-dimensional transoesophageal echocardiography was performed prior to and immediately after MitraClip im... Abstract
Cited 7 times since 2016 (0.9 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 11, Issue 13, 1 1 2016, Pages 1554-1561 Acute effect of MitraClip implantation on mitral valve geometry in patients with functional mitral regurgitation: insights from three-dimensional transoesophageal echocardiography. Al Amri I, Debonnaire P, van der Kley F, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Aims: Our aim was to evaluate the acute effects of transcatheter edge-to-edge mitral valve repair using the MitraClip device on mitral valve geometry in patients with functional mitral regurgitation (FMR). Methods and results: Forty-two patients (age 73 years [IQ range 66.1-78.0], 55% men, 62% ischaemic FMR) with moderate-to-severe and severe FMR treated with the MitraClip were included. Three-dimensional transoesophageal echocardiography was performed prior to and immediately after MitraClip im... Abstract
Cited 29 times since 2016 (3.5 per year) source: EuropePMC
RMD open, Volume 2, Issue 1, 15 3 2016, Pages e000159 Therapeutic and diagnostic outcomes of a standardised, comprehensive care pathway for patients with systemic sclerosis. Meijs J, Schouffoer AA, Ajmone Marsan N, Kroft LJ, Stijnen T, Ninaber MK, Huizinga TW, Vliet Vlieland TP, de Vries-Bouwstra JK
Objectives: To determine the outcomes, including number of medical interventions and initiation of immunosuppressive treatment of a standardised, comprehensive, diagnostic care pathway for patients with systemic sclerosis (SSc). Patient characteristics associated with need for medical interventions and with need for immunosuppressive treatment were determined. Methods: Data were routinely gathered in connection with a 2-day care pathway combining multidisciplinary care and complete diagnostic wo... Abstract
The American journal of cardiology, Volume 117, Issue 7, 2 1 2016, Pages 1167-1172 Comparison of Left Ventricular Volume and Ejection Fraction and Frequency and Extent of Aortic Regurgitation After Operative Repair of Type A Aortic Dissection Among Three Different Surgical Techniques. Regeer MV, Versteegh MI, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Differences in recurrence rate of aortic regurgitation (AR) and extent of left ventricular (LV) remodeling across the different surgical options in patients operated for type A aortic dissection remain unknown. The present evaluation compared the AR recurrence rate and changes in LV volumes and systolic function in valve-sparing aorta replacement (VSAR), supracoronary ascending aorta replacement (SCAR), and aortic valve and aorta replacement (AVAR). A total of 97 patients (58 ± 12 years, 62% men... Abstract
Cited 7 times since 2016 (0.8 per year) source: Scopus
Journal of geriatric cardiology : JGC, Volume 13, Issue 1, 1 1 2016, Pages 31-36 Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years. van der Kley F, van Rosendael PJ, Katsanos S, Kamperidis V, Marsan NA, Karalis I, de Weger A, Palmen M, Bax JJ, Schalij MJ, Delgado V
Objective: To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old. Methods: A total of 240 patients treated with TAVI were divided into two groups according to age ≤ 80 years (n = 105; 43.8%) and > 80 years (n = 135; 56.2%). The baseline characteristics and the procedural outcomes were compared between these two groups of patients. Re... Abstract
Cited 43 times since 2015 (5.1 per year) source: EuropePMC
European heart journal, Volume 37, Issue 10, 18 3 2015, Pages 811-816 Left ventricular systolic function assessment in secondary mitral regurgitation: left ventricular ejection fraction vs. speckle tracking global longitudinal strain. Kamperidis V, Marsan NA, Delgado V, Bax JJ
Aims: Left ventricular (LV) ejection fraction (LVEF) is currently considered for the decision making of patients with mitral regurgitation (MR). However, LVEF represents change in LV volume between end-diastole and end-systole but does not characterize the intrinsic function of the myocardium. In contrast, speckle-tracking global longitudinal strain (GLS) characterizes myocardial deformation. The present study evaluated whether LV GLS may detect further impairment in LV systolic function in dila... Abstract
Cited 3 times since 2015 (0.4 per year) source: EuropePMC
RMD open, Volume 1, Issue 1, 1 1 2015, Pages e000113 A prediction model for progressive disease in systemic sclerosis. Meijs J, Schouffoer AA, Ajmone Marsan N, Stijnen T, Putter H, Ninaber MK, Huizinga TW, de Vries-Bouwstra JK
Objective: To develop a model that assesses the risk for progressive disease in patients with systemic sclerosis (SSc) over the short term, in order to guide clinical management. Methods: Baseline characteristics and 1 year follow-up results of 163 patients with SSc referred to a multidisciplinary healthcare programme were evaluated. Progressive disease was defined as: death, ≥10% decrease in forced vital capacity, ≥15% decrease in diffusing capacity for carbon monoxide, ≥10% decrease in body we... Abstract
Cited 10 times since 2015 (1.2 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 17, Issue 11, 20 3 2015, Pages 1269-1278 Sustained favourable haemodynamics 1 year after TAVI: improvement in NYHA functional class related to improvement of left ventricular diastolic function. Muratori M, Fusini L, Tamborini G, Gripari P, Delgado V, Marsan NA, Ghulam Ali S, Barbier P, Bartorelli AL, Alamanni F, Pepi M
Aims: Despite expected improvement in left ventricular (LV) systolic and diastolic function after transcatheter aortic valve implantation (TAVI), the complex relationship between pre-existent LV systolic and diastolic function and changes in LV haemodynamics and clinical symptoms have been scarcely investigated. This study investigated the presence of pre-operative LV diastolic dysfunction and its improvement over time after TAVI alongside improvement in New York Heart Association (NYHA) class i... Abstract
Cited 1 times since 2015 (0.1 per year) source: EuropePMC
Expert review of cardiovascular therapy, Volume 14, Issue 1, 4 1 2015, Pages 75-86 The role of multimodality imaging in the selection of patients for aortic valve repair. Regeer MV, Versteegh MI, Marsan NA, Bax JJ, Delgado V
Aortic valve sparing surgery for aortic regurgitation and/or aortopathy serves as an alternative to aortic valve and root replacement. One of the advantages of aortic valve sparing surgery over conventional replacement is that there is no need for life-long anticoagulation, which is particularly attractive in young patients who may receive a mechanical prosthesis otherwise. However, successful aortic valve repair requires high expertise. At present, reparability is determined intraoperatively by... Abstract
Cited 6 times since 2015 (0.7 per year) source: EuropePMC
Rheumatology (Oxford, England), Volume 55, Issue 3, 15 3 2015, Pages 504-512 Impact of pulmonary fibrosis and elevated pulmonary pressures on right ventricular function in patients with systemic sclerosis. Yiu KH, Ninaber MK, Kroft LJ, Schouffoer AA, Stolk J, Scherer HU, Meijs J, de Vries-Bouwstra J, Tse HF, Delgado V, Bax JJ, Huizinga TW, Marsan NA
Objectives: Right ventricular (RV) dysfunction is of great prognostic value in patients with SSc. The aim of the present study was to assess in these patients the relationship between pulmonary fibrosis and elevated pulmonary pressure (PHT) with RV function. Methods: A total of 102 SSc patients who underwent thoracic CT and transthoracic echocardiography were included. Speckle tracking-derived RV free wall strain was used to assess RV function. Results: A total of 51 (50%) SSc patients did not h... Abstract
Cited 7 times since 2015 (0.8 per year) source: EuropePMC
Clinical journal of the American Society of Nephrology : CJASN, Volume 10, Issue 10, 25 4 2015, Pages 1740-1748 Cardiac Resynchronization Therapy in CKD Stage 4 Patients. Höke U, Khidir MJ, van der Velde ET, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background and objectives: Cardiac resynchronization therapy (CRT) is a well established heart failure treatment that has shown to improve renal function. However, landmark CRT trials excluded patients with severe renal dysfunction. Therefore, this study evaluated the effect of CRT on renal function and long-term prognosis in patients with stage 4 CKD. Design, setting, participants, & measurements: This study evaluated 73 consecutive CRT patients (71±10 years) with stage 4 CKD who underwent... Abstract