Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
1720 results
Cited 3 times since 2002 (0.1 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 15, Issue 10 Pt 2, 1 1 2002, Pages 1285-1289 Stress echocardiography for risk stratification of patients with chest pain and normal or slightly narrowed coronary arteries. Bigi R, Cortigiani L, Bax JJ, Colombo P, Desideri A, Sponzilli C, Fiorentini C
One hundred twenty-five patients (60 +/- 10 years old, 60 women) with known (35, previous myocardial infarction) or suspected (90) coronary artery disease (CAD) and no more than 50% coronary stenoses underwent pharmacologic (48 dipyridamole and 77 dobutamine) stress echocardiography (SE) and prospective follow-up (36 +/- 22 months) for cardiac death, nonfatal infarction, and unstable angina. The ability of clinical and SE variables to predict the outcome was assessed by the Cox model. A signific... Abstract
Cited 19 times since 2002 (0.9 per year) source: EuropePMC
Diabetes care, Volume 25, Issue 9, 1 1 2002, Pages 1637-1643 Prognostic value of dobutamine-atropine stress myocardial perfusion imaging in patients with diabetes. Schinkel AF, Elhendy A, van Domburg RT, Bax JJ, Vourvouri EC, Sozzi FB, Valkema R, Roelandt JR, Poldermans D
Objective: Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. Research design and methods: A total of 207 consecutive diabetic patients who were unable to undergo exercise stress testing underwent dobutamine-atropine stress myocardial perfusion imaging. Follow-up was successful in 206 of 207 (99.5... Abstract
Cited 18 times since 2002 (0.8 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 22, Issue 3, 1 1 2002, Pages 426-430 The beneficial effect of revascularization on jeopardized myocardium: reverse remodeling and improved long-term prognosis. Mule JD, Bax JJ, Zingone B, Martinelli F, Burelli C, Stefania A, DiSipio L, Soravia G
Objectives: To evaluate the impact of viability/ischemia before revascularization on improvement in systolic performance, reverse remodeling, symptoms and long-term prognosis post-revascularization. Methods: Fifty patients underwent thallium-201 imaging before revascularization to assess stress-induced ischemia and viability ('jeopardized myocardium'). Left ventricular (LV) ejection fraction (EF), LV end-systolic volume index (LVESVI) and LV end-diastolic volume index (LVEDVI) were det... Abstract
Cited 6 times since 2002 (0.3 per year) source: EuropePMC
Circulation, Volume 106, Issue 12 Suppl 1, 1 1 2002, Pages I14-8 Perfusion and contractile reserve in chronic dysfunctional myocardium: relation to functional outcome after surgical revascularization. Bax JJ, Poldermans D, Schinkel AF, Boersma E, Elhendy A, Maat A, Valkema R, Krenning EP, Roelandt JR
Background: Chronic dysfunctional but viable myocardium may exhibit contractile reserve and/or intact perfusion. Segments with intact perfusion without contractile reserve are frequently observed inpatients with ischemic cardiomyopathy. The clinical relevance of this observation is unclear; in particular, the functional outcome after revascularization is unknown. Thus, contractile reserve (using low-dose dobutamine echocardiography) and perfusion (using resting (99m)Tc tetrofosmin) were evaluate... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 10, Issue 7-8, 1 1 2002, Pages 329-330 Contrast medium echocardiography-assisted pericardiocentesis of loculated pericardial fluid. van Houwelingen KG, Bax JJ, Jukema JW, van der Wall EE
Cited 42 times since 2002 (1.9 per year) source: EuropePMC
The American journal of cardiology, Volume 90, Issue 4, 1 1 2002, Pages 379-383 Effectiveness of resynchronization therapy in patients with end-stage heart failure. Molhoek SG, Bax JJ, van Erven L, Bootsma M, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
Biventricular pacing has been introduced to treat patients with end-stage heart failure, and short-term results of this technique are promising. Because data on longer follow-up are limited to 3-month follow-up, the sustained effect of biventricular pacing is unclear and long-term survival is unknown. Forty patients with end-stage heart failure in New York Heart Association (NYHA) functional class III or IV with left ventricular (LV) ejection fraction (EF) 120 ms, and left bundle branch block mo... Abstract
Cited 58 times since 2002 (2.7 per year) source: EuropePMC
American heart journal, Volume 144, Issue 2, 1 1 2002, Pages 198-205 Assessment of diastolic function by cardiovascular magnetic resonance. Paelinck BP, Lamb HJ, Bax JJ, Van der Wall EE, de Roos A
Background: The assessment of diastolic heart function has been hampered by multiple difficulties. Cardiovascular magnetic resonance (CMR) is a new, noninvasive technique to study cardiac function. Methods: The literature on CMR for the analysis of diastolic function and its clinical applications is extensively reviewed. Results: Analysis of ventricular filling velocity and volume flow, volumetric assessment of ventricular chamber volume, analysis of 3-dimensional myocardial strains, and assessm... Abstract
Cited 37 times since 2002 (1.7 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 29, Issue 9, 11 2 2002, Pages 1257-1266 The need for standardisation of cardiac FDG PET imaging in the evaluation of myocardial viability in patients with chronic ischaemic left ventricular dysfunction. Knuuti J, Schelbert HR, Bax JJ
The evaluation of myocardial glucose utilisation with fluorine-18 fluorodeoxyglucose (FDG) and positron emission tomography is currently considered the most reliable tool for the identification of myocardial viability. However, the investigations using FDG imaging to predict improvement in left ventricular (LV) function after revascularisation have reported wide ranges for sensitivity (71%-100%) and, in particular, for specificity (33%-91%). The variable results may be related to differences in... Abstract
Cited 13 times since 2002 (0.6 per year) source: EuropePMC
Cardiovascular research, Volume 55, Issue 1, 1 1 2002, Pages 97-103 Abnormalities in myocardial contractility, metabolism and perfusion reserve in non-stenotic coronary segments in heart failure patients. van den Heuvel AF, Bax JJ, Blanksma PK, Vaalburg W, Crijns HJ, van Veldhuisen DJ
Objective: Myocardial blood flow (MBF) reserve is impaired in congestive heart failure (CHF), while fluorine-18-deoxyglucose (18FDG) uptake is relatively preserved. To determine whether this mismatch could be interpreted as ischemia, we performed dobutamine stress echocardiography (DSE). Methods: 12 males with coronary artery disease (CAD) and CHF were compared with 12 controls with similar CAD but normal left ventricular (LV) function. MBF in non-infarct-related artery areas was assessed using... Abstract
Cited 3 times since 2002 (0.1 per year) source: EuropePMC
The American journal of cardiology, Volume 90, Issue 2, 1 1 2002, Pages 149-152 Sustained favorable long-term prognosis of negative stress echocardiography following uncomplicated myocardial infarction. Bigi R, Cortigiani L, Mariani PR, Bax JJ
Cited 19 times since 2002 (0.9 per year) source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 43, Issue 6, 1 1 2002, Pages 795-802 Sequential (201)Tl imaging and dobutamine echocardiography to enhance accuracy of predicting improved left ventricular ejection fraction after revascularization. Bax JJ, Maddahi J, Poldermans D, Elhendy A, Cornel JH, Boersma E, Roelandt JR, Fioretti PM
Unlabelled: 201Tl imaging and dobutamine echocardiography (DE) can both identify viable myocardium. Prediction of functional outcome after revascularization remains suboptimal with either technique because of the relatively low specificity of (201)Tl and low sensitivity of DE. This study was undertaken to develop an optimal testing strategy for prediction of post-revascularization functional outcome. Methods: Seventy-three patients (mean [+/-SD] left ventricular ejection fraction [LVEF], 32% +/-... Abstract
Cited 21 times since 2002 (1 per year) source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 43, Issue 6, 1 1 2002, Pages 767-772 Prognostic value of dobutamine-atropine stress (99m)Tc-tetrofosmin myocardial perfusion SPECT in patients with known or suspected coronary artery disease. Schinkel AF, Elhendy A, van Domburg RT, Bax JJ, Roelandt JR, Poldermans D
Unlabelled: 99mTc-Tetrofosmin is a recently introduced radioactive isotope for the assessment of myocardial perfusion. Data regarding the prognostic value of stress imaging using this isotope are scarce. The aim of this study was to assess the prognostic value of dobutamine-atropine (99m)Tc-tetrofosmin SPECT for the prediction of late cardiac events in patients with known or suspected coronary artery disease. Methods: A total of 721 consecutive patients with limited exercise capacity underwent d... Abstract
Cited 9 times since 2002 (0.4 per year) source: EuropePMC
European radiology, Volume 12 Suppl 3, 14 2 2002, Pages S177-80 Detection of malignant right coronary artery anomaly by multi-slice CT coronary angiography. Dirksen MS, Bax JJ, Blom NA, Schalij MJ, Jukema WJ, Vliegen HW, van der Wall EE, de Roos A, Lamb HJ
Coronary artery anomalies occur in 0.3-0.8% of the population and infer a high risk for sudden cardiac death in young adults. Diagnosis is usually established during coronary angiography, which is hampered by poor spatial visualization. Magnetic resonance imaging is an alternative, but it is not feasible in the presence of metal objects or claustrophobia. In this report, a 15-year-old boy experienced ventricular fibrillation and was successfully resuscitated. Cardiac catheterization was inconclu... Abstract
Cited 13 times since 2002 (0.6 per year) source: EuropePMC
The American journal of cardiology, Volume 89, Issue 10, 1 1 2002, Pages 1171-1175 Assessment of viable tissue in Q-wave regions by metabolic imaging using single-photon emission computed tomography in ischemic cardiomyopathy. Schinkel AF, Bax JJ, Elhendy A, Boersma E, Vourvouri EC, Sozzi FB, Valkema R, Roelandt JR, Poldermans D
Chronic electrocardiographic Q waves are often believed to reflect irreversibly scarred, transmurally infarcted myocardium. The aim of this study was to evaluate whether residual viable tissue persists in dysfunctional myocardial regions related to chronic Q waves on the surface electrocardiogram. A total of 148 patients with healed myocardial infarction and impaired left ventricular (LV) function with heart failure symptoms underwent electrocardiography and metabolic imaging using technetium (T... Abstract
Cited 14 times since 2002 (0.6 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 29, Issue 6, 10 2 2002, Pages 721-727 Accuracy of PET in predicting functional recovery after revascularisation in patients with chronic ischaemic dysfunction: head-to-head comparison between blood flow, glucose utilisation and water-perfusable tissue fraction. Bax JJ, Fath-Ordoubadi F, Boersma E, Wijns W, Camici PG
Accurate prediction of improvement in left ventricular ejection fraction (LVEF) after revascularisation is critical in the therapeutic decision-making process in patients with chronic ischaemic dysfunction. Positron emission tomography (PET) allows non-invasive evaluation of myocardial blood flow (MBF), metabolic rate of glucose (MRG, absolute and relative) and the water-perfusable tissue fraction (PTF). Each of these indices has been proposed for the prediction of functional recovery. Their rel... Abstract
Cited 26 times since 2002 (1.2 per year) source: EuropePMC
The American journal of cardiology, Volume 89, Issue 8, 1 1 2002, Pages 964-968 Prediction of mortality in heart transplant recipients by stress technetium-99m tetrofosmin myocardial perfusion imaging. Elhendy A, van Domburg RT, Vantrimpont P, Poldermans D, Bax JJ, van Gelder T, Baan CC, Schinkel A, Roelandt JR, Balk AH
Cardiac allograft vasculopathy is a major cause of mortality in heart transplant recipients. The aim of this study was to assess the prognostic value of stress myocardial perfusion imaging in heart transplant recipients. We studied 166 patients (age 54 +/- 10 years, 140 men) by symptom-limited bicycle exercise or dobutamine (up to 40 microg/kg/min) stress myocardial perfusion imaging 7.4 +/- 2.5 years after heart transplantation. An intravenous dose of 370 MBq of technetium-99m tetrofosmin was i... Abstract
Cited 6 times since 2002 (0.3 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 29, Issue 4, 19 3 2002, Pages 452-457 Feasibility, safety and image quality of cardiac FDG studies during hyperinsulinaemic-euglycaemic clamping. Bax JJ, Visser FC, Poldermans D, van Lingen A, Elhendy A, Boersma E, Visser CA
Fluorine-18 fluorodeoxyglucose (FDG) imaging for the assessment of myocardial viability has become an integral part of the diagnostic and prognostic work-up of patients with ischaemic cardiomyopathy. To ensure good image quality, in particular in patients with diabetes mellitus, hyperinsulinaemic-euglycaemic clamping has been proposed. In this study we evaluated the safety and the image quality of cardiac FDG imaging during clamping in a large group of patients, including a subgroup with diabete... Abstract
Cited 10 times since 2002 (0.4 per year) source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Volume 4, Issue 3, 1 1 2002, Pages 353-357 Noninvasive and invasive evaluation of noncompaction cardiomyopathy. Bax JJ, Atsma DE, Lamb HJ, Rebergen SA, Bootsma M, Voogd PJ, Somer S, Schalij MJ, de Roos A, van der Wall EE
Noncompaction cardiomyopathy is a recently described rare congenital cardiomyopathy; patients can be asymptomatic or develop diastolic and/or systolic left ventricular dysfunction with heart failure, systemic emboli or ventricular arrhythmias. Long-term prognosis is poor. Currently, diagnosis is based on findings on 2D echocardiography; in the current case report we demonstrate the use of MRI to diagnose noncompaction cardiomyopathy. Abstract
Cited 20 times since 2001 (0.9 per year) source: EuropePMC
The Journal of clinical endocrinology and metabolism, Volume 86, Issue 10, 1 1 2001, Pages 4638-4643 Six months of recombinant human GH therapy in patients with ischemic cardiac failure does not influence left ventricular function and mass. Smit JW, Janssen YJ, Lamb HJ, van der Wall EE, Stokkel MP, Viergever E, Biermasz NR, Bax JJ, Vliegen HW, de Roos A, Romijn JA, Roelfsema F
Beneficial effects of recombinant human GH on cardiac function have been reported in humans with GH deficiency and in patients with idiopathic dilated cardiomyopathy. No randomized controlled trial has been performed on the effects of recombinant human GH on cardiac function in patients with ischemic cardiac failure. We therefore randomly assigned 22 patients with ischemic cardiac failure (left ventricular ejection fraction, Abstract
Cited 104 times since 2000 (4.4 per year) source: EuropePMC
The American journal of cardiology, Volume 86, Issue 12, 1 1 2000, Pages 1299-1305 Comparison of gated single-photon emission computed tomography with magnetic resonance imaging for evaluation of left ventricular function in ischemic cardiomyopathy. Bax JJ, Lamb H, Dibbets P, Pelikan H, Boersma E, Viergever EP, Germano G, Vliegen HW, de Roos A, Pauwels EK, Van der Wall EE
To perform a head-to-head comparison between magnetic resonance imaging (MRI) and gated single-photon emission computed tomography (SPECT) for the evaluation of left ventricular (LV) function (LV ejection fraction [LVEF], LV volumes, and regional wall motion) in patients with ischemic cardiomyopathy, we studied 22 patients with chronic coronary artery disease and LV dysfunction. Multislice, multiphase echoplanar MRI was performed with Philips Gyroscan ACS-NT15. Image analysis was performed using... Abstract