Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
251 results
Critical care medicine, Volume 35, Issue 1, 1 1 2007, Pages 321-322 Effect of thoracic epidural anesthesia on right ventricular function and homeometric autoregulation. Steendijk P
Cited 236 times since 2006 (13.5 per year) source: EuropePMC
European heart journal, Volume 28, Issue 1, 22 4 2006, Pages 33-41 Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients. Ypenburg C, Schalij MJ, Bleeker GB, Steendijk P, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Bax JJ
Aims: At present, 20-30% of patients do not respond to cardiac resynchronization therapy (CRT). In this study, the relation between the extent of viable myocardium and scar tissue vs. response to CRT was evaluated. In addition, the presence of scar tissue in the left ventricular (LV) lead position was specifically related to response to CRT. Methods and results: A total of 51 consecutive patients with ischaemic heart failure and substantial LV dyssynchrony undergoing CRT were included. All patie... Abstract
Cited 61 times since 2006 (3.5 per year) source: EuropePMC
The American journal of cardiology, Volume 99, Issue 1, 9 2 2006, Pages 68-74 Relative merits of M-mode echocardiography and tissue Doppler imaging for prediction of response to cardiac resynchronization therapy in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Bleeker GB, Schalij MJ, Boersma E, Holman ER, Steendijk P, van der Wall EE, Bax JJ
M-mode echocardiography (using the septal-to-posterior wall motion delay [SPWMD]) and color-coded tissue Doppler imaging (TDI; using the septal-to-lateral delay in peak systolic velocity) have been proposed for assessment of left ventricular (LV) dyssynchrony and prediction of response to cardiac resynchronization therapy (CRT). In this study, a head-to-head comparison between M-mode echocardiography and color-coded TDI was performed for assessment of LV dyssynchrony and prediction of response t... Abstract
Cited 166 times since 2006 (9.5 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 48, Issue 11, 9 2 2006, Pages 2243-2250 Cardiac resynchronization therapy in patients with a narrow QRS complex. Bleeker GB, Holman ER, Steendijk P, Boersma E, van der Wall EE, Schalij MJ, Bax JJ
Objectives: The purpose of this study was to evaluate the effects of cardiac resynchronization therapy (CRT) in heart failure patients with narrow QRS complex ( or =120 ms). Patients with narrow QRS complex are currently not eligible for CRT, and the potential effects of CRT are not well studied. Methods: Thirty-three consecutive patients with narrow QRS complex and 33 consecutive patients with wide QRS complex (control group) were prospectively included. All patients needed to have LV dyssynchr... Abstract
Cited 22 times since 2006 (1.3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 82, Issue 5, 1 1 2006, Pages 1721-1727 Beneficial hemodynamic and clinical effects of surgical ventricular restoration in patients with ischemic dilated cardiomyopathy. Tulner SA, Bax JJ, Bleeker GB, Steendijk P, Klautz RJ, Holman ER, Schalij MJ, Dion RA, van der Wall EE
Background: Surgical ventricular restoration is increasingly applied in patients with ischemic dilated cardiomyopathy. Previous studies show promising results with regard to survival and clinical outcome. However, a comprehensive midterm analysis of this approach on left ventricular (LV) and right ventricular function is not yet available. We investigated biventricular function and clinical status at 6-month follow-up. Methods: We investigated the effects of surgical ventricular restoration on c... Abstract
Cited 59 times since 2006 (3.4 per year) source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 47, Issue 10, 1 1 2006, Pages 1565-1570 Extent of viability to predict response to cardiac resynchronization therapy in ischemic heart failure patients. Ypenburg C, Schalij MJ, Bleeker GB, Steendijk P, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Bax JJ
Unlabelled: The response to cardiac resynchronization therapy (CRT) varies significantly among individuals. Preliminary data suggest that the presence of myocardial viability may be important for response to CRT. The aim of this study was to evaluate whether the extent of viability could predict response to CRT after 6 mo. Methods: Sixty-one consecutive patients with advanced heart failure, left ventricular ejection fraction < 35%, QRS duration > 120 ms, and chronic coronary artery disease... Abstract
Cited 52 times since 2006 (2.9 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 132, Issue 3, 1 1 2006, Pages 610-620 Surgical ventricular restoration in patients with ischemic dilated cardiomyopathy: evaluation of systolic and diastolic ventricular function, wall stress, dyssynchrony, and mechanical efficiency by pressure-volume loops. Tulner SA, Steendijk P, Klautz RJ, Bax JJ, Schalij MJ, van der Wall EE, Dion RA
Objectives: Surgical ventricular restoration aims at improving cardiac function by normalization of left ventricular shape and size. Recent studies indicate that surgical ventricular restoration is highly effective with an excellent 5-year outcome in patients with ischemic dilated cardiomyopathy. We used pressure-volume analysis to investigate acute changes in systolic and diastolic left ventricular function, mechanical dyssynchrony and efficiency, and wall stress. Methods: In 3 patient groups (... Abstract
Cited 1 times since 2006 (0.1 per year) source: EuropePMC
Clinical physiology and functional imaging, Volume 26, Issue 4, 1 1 2006, Pages 220-223 The effect of lung inflation on absolute ventricular volume measurement by conductance. Haney MF, Steendijk P, Johansson G, Biber B
Background: Conductance catheter in vivo ventricular volume measurements during lung ventilation may provide important information on left ventricular (LV) function. Breathing potentially may alter parallel conductance (V(c)), complicating interpretation of the conductance-derived volume signals. The effects of controlled positive pressure lung inflation (PPLI) on measured parallel conductance with dual-field conductance volumetry were investigated. Methods: Eight anaesthetized pigs were instrum... Abstract
Cited 93 times since 2006 (5.2 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 291, Issue 5, 26 4 2006, Pages H2424-30 Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat. Hessel MH, Steendijk P, den Adel B, Schutte CI, van der Laarse A
We characterized hemodynamics and systolic and diastolic right ventricular (RV) function in relation to structural changes in the rat model of monocrotaline (MCT)-induced pulmonary hypertension. Rats were treated with MCT at 30 mg/kg body wt (MCT30, n = 15) and 80 mg/kg body wt (MCT80, n = 16) to induce compensated RV hypertrophy and RV failure, respectively. Saline-treated rats served as control (Cont, n = 13). After 4 wk, a pressure-conductance catheter was introduced into the RV to assess pre... Abstract
Cited 35 times since 2006 (1.9 per year) source: EuropePMC
The American journal of cardiology, Volume 98, Issue 2, 19 3 2006, Pages 230-235 Cardiac resynchronization therapy in patients with systolic left ventricular dysfunction and symptoms of mild heart failure secondary to ischemic or nonischemic cardiomyopathy. Bleeker GB, Schalij MJ, Holman ER, Steendijk P, van der Wall EE, Bax JJ
Cardiac resynchronization therapy (CRT) is beneficial in selected patients with moderate to severe heart failure (New York Heart Association [NYHA] classes III to IV). Patients with mildly symptomatic heart failure (NYHA class II) are currently not eligible for CRT and the potential beneficial effects in these patients have not been well studied. Fifty consecutive patients in NYHA class II heart failure and 50 consecutive patients in NYHA classes III to IV (control group) were prospectively incl... Abstract
Cited 9 times since 2006 (0.5 per year) source: EuropePMC
Clinical research in cardiology : official journal of the German Cardiac Society, Volume 95, Issue 6, 18 3 2006, Pages 344-348 Coronary vasospasm-induced acute diastolic dysfunction in a patient with Raynaud's phenomenon. Tschöpe C, Westermann D, Steendijk P, Kasner M, Rudwaleit M, Schwimmbeck PL, Poller WC, Schultheiss HP
We present the case of a patient with severe dyspnea and Raynaud's phenomenon. We could clarify, using invasive techniques including left ventricular conductance catheterization and coronary ergonovine provocation, that isolated diastolic dysfunction induced by coronary vasospasm were responsible for the symptoms. Systolic function was not affected. Short-term infusions with the prostacyclin analogue iloprost, known to act as a disease-modifying agent in patients suffering from Raynaud'... Abstract
Cited 82 times since 2006 (4.6 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 291, Issue 4, 5 1 2006, Pages H1580-6 Right and left ventricular function after chronic pulmonary artery banding in rats assessed with biventricular pressure-volume loops. Faber MJ, Dalinghaus M, Lankhuizen IM, Steendijk P, Hop WC, Schoemaker RG, Duncker DJ, Lamers JM, Helbing WA
In many patients with congenital heart disease, the right ventricle (RV) is subjected to abnormal loading conditions. To better understand the state of compensated RV hypertrophy, which could eventually progress to decompensation, we studied the effects of RV pressure overload in rats. In the present study, we report the biventricular adaptation to 6 wk of pulmonary artery banding (PAB). PAB resulted in an RV pressure overload to approximately 60% of systemic level and a twofold increase in RV m... Abstract
Cited 18 times since 2006 (1 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 2, Issue 1, 1 1 2006, Pages 91-100 Use of Impella Recover(R) LP 2.5 left ventricular assist device during high-risk percutaneous coronary interventions; clinical, haemodynamic and biochemical findings. Valgimigli M, Steendijk P, Serruys PW, Vranckx P, Boomsma F, Onderwater E, Vaina S, Ligthart JM, McFadden E, van der Ent M, de Jaegere P, Sianos G
Aim: To investigate in terms of clinical, haemodynamic and biochemical profile the safety and efficacy of the Impella Recover(R) LP 2.5 left ventricular assist device during elective high risk percutaneous coronary interventions (HR-PCI). Methods and results: Ten out of twelve patients were initially enrolled to receive PCI supported by the Impella catheter; eight underwent pressure-volume (PV) loop analysis while one patient was monitored by intra-cardiac echocardiographic. Free haemoglobin (fH... Abstract
Cited 5 times since 2006 (0.3 per year) source: EuropePMC
Journal of cardiothoracic and vascular anesthesia, Volume 20, Issue 3, 5 1 2006, Pages 340-346 Time-varying elastance concept applied to the relation of carotid arterial flow velocity and ventricular area. Broscheit JA, Weidemann F, Strotmann J, Steendijk P, Karle H, Roewer N, Greim CA
Objective: In this study, the relationship V(f)AR, which was obtained from carotid blood-flow velocity (V(f)) and the cross-sectional area (A) of the left ventricle, was used to assess changes in left ventricular (LV) systolic performance as indicated by the LV pressure-volume relationship (PVR) and end-systolic LV elastance (E(es)). Background: The relationship of maximum systolic V(f) as a surrogate for LV pressure and end-systolic LV area as a surrogate for end-systolic LV volume may allow fo... Abstract
Cited 50 times since 2006 (2.8 per year) source: EuropePMC
Nature clinical practice. Cardiovascular medicine, Volume 3, Issue 4, 1 1 2006, Pages 213-219 Left ventricular dyssynchrony in patients with heart failure: pathophysiology, diagnosis and treatment. Bleeker GB, Bax JJ, Steendijk P, Schalij MJ, van der Wall EE
The number of patients with chronic heart failure is increasing rapidly in the Western world. Despite the introduction of new pharmacologic therapies, the prognosis of these patients remains poor. Left ventricular (LV) dyssynchrony is a frequently observed feature in patients with heart failure, and is recognized as an important predictor of poor outcome if left untreated. The presence of LV dyssynchrony leads to inefficient LV contraction with a decreased cardiac output. Moreover, patients with... Abstract
Cited 17 times since 2006 (0.9 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 92 Suppl 1, 1 1 2006, Pages i14-8 Acquired right ventricular dysfunction. Bleeker GB, Steendijk P, Holman ER, Yu CM, Breithardt OA, Kaandorp TA, Schalij MJ, van der Wall EE, Bax JJ, Nihoyannopoulos P
Cited 109 times since 2006 (6 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 92 Suppl 1, 1 1 2006, Pages i19-26 Assessing right ventricular function: the role of echocardiography and complementary technologies. Bleeker GB, Steendijk P, Holman ER, Yu CM, Breithardt OA, Kaandorp TA, Schalij MJ, van der Wall EE, Nihoyannopoulos P, Bax JJ
Cited 110 times since 2006 (6.1 per year) source: EuropePMC
Circulation, Volume 113, Issue 10, 6 1 2006, Pages 1295-1304 Hemodynamic effects of long-term cardiac resynchronization therapy: analysis by pressure-volume loops. Steendijk P, Tulner SA, Bax JJ, Oemrawsingh PV, Bleeker GB, van Erven L, Putter H, Verwey HF, van der Wall EE, Schalij MJ
Background: Acute hemodynamic effects of cardiac resynchronization therapy (CRT) were reported previously, but detailed invasive studies showing hemodynamic consequences of long-term CRT are not available. Methods and results: We studied 22 patients scheduled for implantation of a CRT device based on conventional criteria (New York Heart Association class III or IV, left ventricular [LV] ejection fraction 120 ms). During diagnostic catheterization before CRT, we acquired pressure-volume loops us... Abstract
Cited 18 times since 2006 (1 per year) source: EuropePMC
Nature clinical practice. Cardiovascular medicine, Volume 3 Suppl 1, 1 1 2006, Pages S94-100 Intramyocardial injection of skeletal myoblasts: long-term follow-up with pressure-volume loops. Steendijk P, Smits PC, Valgimigli M, van der Giessen WJ, Onderwater EE, Serruys PW
The human heart has a limited capacity for self-repair because, unlike most other cells, cardiomyocytes do not regenerate. Therefore, if a substantial number of myocytes is lost after a myocardial infarction, the performance of the heart may become severely limited, leading to a condition of heart failure. Recently, cell transplantation has emerged as a potential therapy for patients with end-stage heart failure. Of the various cell types being investigated for this purpose, skeletal myoblasts a... Abstract
Cited 458 times since 2006 (25.1 per year) source: EuropePMC
Circulation, Volume 113, Issue 7, 13 2 2006, Pages 969-976 Effect of posterolateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy. Bleeker GB, Kaandorp TA, Lamb HJ, Boersma E, Steendijk P, de Roos A, van der Wall EE, Schalij MJ, Bax JJ
Background: Currently, one third of patients treated with cardiac resynchronization therapy (CRT) do not respond. Nonresponse to CRT may be explained by the presence of scar tissue in the posterolateral left ventricular (LV) segments, which may result in ineffective LV pacing and inadequate LV resynchronization. In the present study, the relationship between transmural posterolateral scar tissue and response to CRT was evaluated. Methods and results: Forty consecutive patients with end-stage hea... Abstract