Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
170 results
Cited 25 times since 2011 (2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 97, Issue 24, 11 2 2011, Pages 2063-2068 Intrinsic biventricular dysfunction in Marfan syndrome. de Witte P, Aalberts JJ, Radonic T, Timmermans J, Scholte AJ, Zwinderman AH, Mulder BJ, Groenink M, van den Berg MP
Background: Marfan syndrome (MFS) is an autosomal, dominantly inherited, connective tissue disorder usually caused by a mutation in the fibrillin-1 gene (FBN1). As fibrillin-1 is a component of the extracellular matrix of the myocardium, mutations in FBN1 may cause impairment of ventricular function. Furthermore, aortic elasticity is decreased in patients with MFS, which might also impair ventricular function. We assessed biventricular function and the influence of aortic elasticity in patients... Abstract
Cited 1 times since 2011 (0.1 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 19, Issue 10, 1 1 2011, Pages 440-441 Paroxysmal mechanical aortic valve prosthesis dysfunction: capturing the right moment. Sorgdrager BJ, Tavilla G, van der Wall EE, Scholte AJ
Cited 8 times since 2011 (0.6 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 38, Issue 11, 18 3 2011, Pages 2050-2057 Relationship between vascular stiffness and stress myocardial perfusion imaging in asymptomatic patients with diabetes. Roos CJ, Djaberi R, Schuijf JD, de Koning EJ, Rabelink TJ, Smit JW, Pereira AM, Al Younis I, van der Hiel B, Scholte AJ, Bax JJ, Jukema JW
Purpose: Vascular stiffness may potentially be used as a screening tool to identify asymptomatic patients with diabetes with abnormal myocardial perfusion. The purpose of this study was therefore to determine the association between vascular stiffness, measured in term of pulse wave velocity (PWV) and augmentation index (AIx), and abnormal myocardial perfusion imaging (MPI) in asymptomatic patients with diabetes. Methods: Prospectively, 160 asymptomatic patients with diabetes (mean age 51 years,... Abstract
Cited 31 times since 2011 (2.4 per year) source: EuropePMC
Journal of magnetic resonance imaging : JMRI, Volume 34, Issue 3, 14 2 2011, Pages 526-531 Age-related and regional changes of aortic stiffness in the Marfan syndrome: assessment with velocity-encoded MRI. Westenberg JJ, Scholte AJ, Vaskova Z, van der Geest RJ, Groenink M, Labadie G, van den Boogaard PJ, Radonic T, Hilhorst-Hofstee Y, Mulder BJ, Kroft LJ, Reiber JH, de Roos A
Purpose: To study age-related change in aortic stiffness in patients with Marfan syndrome (MFS) versus healthy volunteers using velocity-encoded (VE) MRI. Materials and methods: Twenty-five MFS patients (age range, 18-63 years; mean age 36 ± 14 years, 13 men) and 25 age-/gender-matched healthy volunteers were examined with VE-MRI. Aortic stiffness was expressed by pulse wave velocity (PWV), assessed in the proximal and distal part of the aorta and in the total aorta. PWV was compared between pat... Abstract
The international journal of cardiovascular imaging, Volume 28, Issue 3, 19 3 2011, Pages 563-565 Does heart rate influence CMR image quality of the coronary vessel wall? van der Wall EE, Kröner EJ, Siebelink HM, Scholte AJ, Schalij MJ
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 18, Issue 3, 1 1 2011, Pages 393-395 Cardiac risk assessment in asymptomatic diabetes: combining [corrected] different imaging modalities and surrogate markers? Scholte AJ
Cited 24 times since 2011 (1.8 per year) source: EuropePMC
Clinical genetics, Volume 80, Issue 4, 31 5 2011, Pages 346-353 Critical appraisal of the revised Ghent criteria for diagnosis of Marfan syndrome. Radonic T, de Witte P, Groenink M, de Bruin-Bon RA, Timmermans J, Scholte AJ, van den Berg MP, Baars MJ, van Tintelen JP, Kempers M, Zwinderman AH, Mulder BJ
Marfan syndrome (MFS) is a connective tissue disorder with major features in cardiovascular, ocular and skeletal systems. Recently, diagnostic criteria were revised where more weight was given to the aortic root dilatation. We applied the revised Marfan nosology in an established adult Marfan population to define practical repercussions of novel criteria for clinical practice and individual patients. Out of 180 MFS patients, in 91% (n = 164) the diagnosis of MFS remained. Out of 16 patients with... Abstract
The international journal of cardiovascular imaging, Volume 28, Issue 3, 26 4 2011, Pages 551-554 Aortic stiffness in type-1 diabetes mellitus; beware of hypertension. van der Wall EE, Siebelink HM, Scholte AJ, Schalij MJ
Cited 2 times since 2011 (0.2 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 18, Issue 1, 1 1 2011, Pages 192-195 Myocardial perfusion scintigraphy before and after cardioversion for atrial fibrillation: recovery of quantitative parameters. Rietbergen DD, Scholte AJ, Al Younis I, Stokkel MP
Cited 17 times since 2010 (1.3 per year) source: EuropePMC
Human mutation, Volume 31, Issue 12, 1 1 2010, Pages E1915-27 The clinical spectrum of missense mutations of the first aspartic acid of cbEGF-like domains in fibrillin-1 including a recessive family. Hilhorst-Hofstee Y, Rijlaarsdam ME, Scholte AJ, Swart-van den Berg M, Versteegh MI, van der Schoot-van Velzen I, Schäbitz HJ, Bijlsma EK, Baars MJ, Kerstjens-Frederikse WS, Giltay JC, Hamel BC, Breuning MH, Pals G
Marfan syndrome (MFS) is a dominant disorder with a recognizable phenotype. In most patients with the classical phenotype mutations are found in the fibrillin-1 gene (FBN1) on chromosome 15q21. It is thought that most mutations act in a dominant negative way or through haploinsufficiency. In 9 index cases referred for MFS we detected heterozygous missense mutations in FBN1 predicted to substitute the first aspartic acid of different calcium-binding Epidermal Growth Factor-like (cbEGF) fibrillin-... Abstract
Cited 16 times since 2010 (1.2 per year) source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 12, Issue 2, 24 4 2010, Pages 148-155 Subclinical left ventricular dysfunction and coronary atherosclerosis in asymptomatic patients with type 2 diabetes. Scholte AJ, Nucifora G, Delgado V, Djaberi R, Boogers MJ, Schuijf JD, Kharagjitsingh AV, Jukema JW, van der Wall EE, Kroft LJ, de Roos A, Bax JJ
Aims: The aim of the present study was to evaluate whether subclinical left ventricular (LV) systolic dysfunction is independently related to subclinical coronary atherosclerosis in type 2 diabetic patients and if it could provide incremental information over baseline characteristics to identify high-risk patients. Methods and results: A total of 234 asymptomatic, type 2 diabetic patients without overt LV systolic dysfunction underwent coronary artery calcium (CAC) scoring and two-dimensional ec... Abstract
Cited 28 times since 2010 (2.1 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 12, 26 4 2010, Pages 1747-1753 Usefulness of hypertriglyceridemic waist phenotype in type 2 diabetes mellitus to predict the presence of coronary artery disease as assessed by computed tomographic coronary angiography. de Graaf FR, Schuijf JD, Scholte AJ, Djaberi R, van Velzen JE, Roos CJ, Kroft LJ, de Roos A, van der Wall EE, Wouter Jukema J, Després JP, Bax JJ
The present study tested whether in patients with type 2 diabetes mellitus (DM) the combination of increased waist circumference and increased plasma triglyceride (TG) levels can predict the presence of coronary artery disease (CAD) as assessed by multidetector computed tomographic coronary angiography (CTA). In 202 patients with type 2 DM who were clinically referred for CTA, waist circumference and TG levels were measured. Patients were divided into 4 groups according to waist circumference me... Abstract
Cited 5 times since 2010 (0.4 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 4, 6 1 2010, Pages 635-638 Assessment of left ventricular volumes; reliable by gated SPECT? van derWall EE, Scholte AJ, Siebelink HM, Bax JJ
Cited 13 times since 2010 (0.9 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 6, 21 3 2010, Pages 718-726 Predictive value of multislice computed tomography variables of atherosclerosis for ischemia on stress-rest single-photon emission computed tomography. van Velzen JE, Schuijf JD, van Werkhoven JM, Herzog BA, Pazhenkottil AP, Boersma E, de Graaf FR, Scholte AJ, Kroft LJ, de Roos A, Stokkel MP, Jukema JW, Kaufmann PA, van der Wall EE, Bax JJ
Background: previous studies have shown that the presence of stenosis alone on multislice computed tomography (MSCT) has a limited positive predictive value for the presence of ischemia on myocardial perfusion imaging (MPI). The purpose of this study was to assess which variables of atherosclerosis on MSCT angiography are related to ischemia on MPI. Methods and results: both MSCT and MPI were performed in 514 patients. On MSCT, the calcium score, degree of stenosis (≥ 50% and ≥ 70% stenosis), an... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 26, Issue 8, 8 2 2010, Pages 893-896 Gated myocardial SPECT imaging; true additional value in AMI? van der Wall EE, Scholte AJ, Bax JJ
Cited 4 times since 2010 (0.3 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 26, Issue 5, 1 1 2010, Pages 537-540 Echocardiography in Takotsubo cardiomyopathy; a useful approach? van der Wall EE, Holman ER, Scholte AJ, Bax JJ
Cited 8 times since 2010 (0.6 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 37, Issue 9, 26 4 2010, Pages 1736-1744 The consequences of a new software package for the quantification of gated-SPECT myocardial perfusion studies. van der Veen BJ, Scholte AJ, Dibbets-Schneider P, Stokkel MP
Purpose: Semiquantitative analysis of myocardial perfusion scintigraphy (MPS) has reduced inter- and intraobserver variability, and enables researchers to compare parameters in the same patient over time, or between groups of patients. There are several software packages available that are designed to process MPS data and quantify parameters. In this study the performances of two systems, quantitative gated SPECT (QGS) and 4D-MSPECT, in the processing of clinical patient data and phantom data we... Abstract
Cited 31 times since 2010 (2.2 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 4, 17 3 2010, Pages 433-442 Reduced left ventricular torsion early after myocardial infarction is related to left ventricular remodeling. Nucifora G, Marsan NA, Bertini M, Delgado V, Siebelink HM, van Werkhoven JM, Scholte AJ, Schalij MJ, van der Wall EE, Holman ER, Bax JJ
Background: Left ventricular (LV) torsion is emerging as a sensitive parameter of LV systolic myocardial performance. The aim of the present study was to explore the effects of acute myocardial infarction (AMI) on LV torsion and to determine the value of LV torsion early after AMI in predicting LV remodeling at 6-month follow-up. Methods and results: A total of 120 patients with a first ST-segment elevation AMI (mean+/-SD age, 59+/-10 years; 73% male) were included. All patients underwent primar... Abstract
Cited 2 times since 2010 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 7, 8 2 2010, Pages 939-942 Stress imaging in patients with diabetes; routine practice? van der Wall EE, Scholte AJ, Holman ER, Bax JJ
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 6 Suppl G, 1 1 2010, Pages G94-G100 Function and anatomy: SPECT-MPI and MSCT coronary angiography. Scholte AJ, Roos CJ, van Werkhoven JM
For the diagnosis of coronary artery disease (CAD), non-invasive cardiac imaging is indispensable. Myocardial perfusion imaging (MPI) by single photon emission computed tomography (SPECT) investigates the pathophysiological consequences of luminal obstructive CAD, while multislice computed tomography coronary angiography (CTA) indicates the presence, extent and location of coronary atherosclerosis. The integration of CTA and SPECT data may provide important information which may be useful for pa... Abstract