Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
112 results
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 10, Issue 12, 1 1 2015, Pages 1488-1492 How should I treat recurrent concomitant para-ring and valvular mitral regurgitation after surgical mitral valve repair in a high-risk patient? van Rosendael P, van der Kley F, Martina B, Palmen M, Delgado V, Schillinger W, von Bardeleben RS, Yeo KK, Ho KW, Jack Tan WC
Cited 9 times since 2015 (1 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 2, 1 1 2015, Pages 102-108 Left ventricular assist device for end-stage heart failure: results of the first LVAD destination program in the Netherlands. Haeck ML, Beeres SL, Höke U, Palmen M, Couperus LE, Delgado V, Logeman EA, Maas JJ, Klautz RJ, Schalij MJ, Verwey HF
Purpose: Mechanical circulatory support with a continuous-flow left ventricular assist device (LVAD) may be a valuable treatment in end-stage heart failure patients for an extended period of time. The purpose of this study was to evaluate the safety and efficacy of implantation of a continuous-flow LVAD in end-stage heart failure patients within the first destination program in the Netherlands. Methods: A third-generation LVAD was implanted in 16 heart failure patients (age 61 ± 8; 81 % male; le... Abstract
Cited 4 times since 2014 (0.4 per year) source: Scopus
The international journal of cardiovascular imaging, Volume 31, Issue 1, 17 3 2014, Pages 37-43 Pericardial effusion following transcatheter aortic valve implantation: echocardiography and multi-detector row computed tomography evaluation. Katsanos S, van Rosendael P, Kamperidis V, van der Kley F, Regeer M, Al-Amri I, Karalis I, Palmen M, de Weger A, Marsan NA, Bax JJ, Delgado V
Although pericardial effusion (PE) early after transcatheter aortic valve implantation (TAVI) has been reported in few registries, late PE at follow-up remains unexplored. Particularly, after transapical TAVI, diagnosis of PE with transthoracic echocardiography (TTE) may be challenging. The present evaluation assessed the incidence of PE early after TAVI and at 1 month follow-up using TTE and multi-detector computed tomography (MDCT). The agreement between TTE and MDCT to diagnose the presence a... Abstract
Cited 22 times since 2014 (2.2 per year) source: Scopus
British journal of anaesthesia, Volume 112, Issue 6, 3 1 2014, Pages 1005-1014 Cardiospecific sevoflurane treatment quenches inflammation but does not attenuate myocardial cell damage markers: a proof-of-concept study in patients undergoing mitral valve repair. Kortekaas KA, van der Baan A, Aarts LP, Palmen M, Cobbaert CM, Verhagen JC, Engbers FH, Klautz RJ, Lindeman JH
Background: Inflammation is considered a key mediator of complications after cardiac surgery. Sevoflurane has been shown to quench inflammation and to provide cardioprotection in preclinical studies. Clinical studies using sevoflurane confirm this effect on inflammation but do not consistently show clinical benefits. This paradox may indicate that the contribution of inflammation to postoperative sequalae is less than commonly thought or that systemic doses are too low in their local concentrati... Abstract
Cited 48 times since 2014 (4.7 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 148, Issue 4, 25 4 2014, Pages 1583-1590 Ascending aorta dilation in association with bicuspid aortic valve: a maturation defect of the aortic wall. Grewal N, Gittenberger-de Groot AC, Poelmann RE, Klautz RJ, Lindeman JH, Goumans MJ, Palmen M, Mohamed SA, Sievers HH, Bogers AJ, DeRuiter MC
Objective: Patients with a bicuspid aortic valve have increased susceptibility to the development of ascending aortic dilation and dissection compared with persons with a tricuspid valve. To unravel a possible different mechanism underlying dilation in bicuspidy and tricuspidy, a comparison of the structure of the aortic wall was made. Methods: Ascending aortic wall biopsies were divided into 4 groups: bicuspid (n=36) and tricuspid (n=23) without and with dilation. The expression of vascular smo... Abstract
Cited 16 times since 2013 (1.5 per year) source: Scopus
The American journal of cardiology, Volume 112, Issue 11, 13 2 2013, Pages 1800-1806 Multidetector row computed tomography parameters associated with paravalvular regurgitation after transcatheter aortic valve implantation. Katsanos S, Ewe SH, Debonnaire P, van der Kley F, de Weger A, Palmen M, Scholte AJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Multidetector row computed tomographic (MDCT) assessment of aortic annulus dimensions and frame position and deployment have been associated with paravalvular aortic regurgitation (PAVR) after transcatheter aortic valve implantation (TAVI). The present evaluation investigated the (pre- and postprocedure) MDCT associates of PAVR ≥2+. In total, 123 patients referred for TAVI underwent clinical evaluation, transthoracic echocardiography, and pre- and post-TAVI MDCT. Pre-TAVI MDCT measurements of th... Abstract
Cited 14 times since 2013 (1.3 per year) source: Scopus
Interactive cardiovascular and thoracic surgery, Volume 17, Issue 3, 4 1 2013, Pages 523-530 Pre-existing endothelial cell activation predicts vasoplegia after mitral valve surgery. Kortekaas KA, Lindeman JH, Reinders ME, Palmen M, Klautz RJ, de Groot PG, Roest M
Objectives: Post-cardiac surgery vasoplegia is a common complication of cardiac surgery, characterized by profound loss of systemic vascular resistance. This results in severe hypotension, high cardiac output and metabolic acidosis reflecting inadequate tissue perfusion. The pathophysiological mechanisms underlying this syndrome remain unknown. We hypothesized that this vasoplegia reflects endothelial dysfunction, either as pre-existing condition or as a consequence of the surgical procedure. Me... Abstract
Cited 5 times since 2013 (0.5 per year) source: Scopus
The American journal of cardiology, Volume 112, Issue 5, 24 4 2013, Pages 714-719 Mitral valve geometry and hemodynamics after surgical mitral valve annuloplasty and implications for percutaneous treatment of patients with recurrent mitral regurgitation. Al Amri I, Debonnaire P, Witkowski T, van der Kley F, Palmen M, de Weger A, Klautz RJ, Bax JJ, Schalij MJ, Ajmone Marsan N, Delgado V
The feasibility of transcatheter mitral valve therapy (edge-to-edge or valve-in-ring technique) in patients with significant mitral regurgitation (MR) recurrence after surgical restrictive mitral valve annuloplasty remains unknown. The aim of the present study was to investigate the eligibility for transcatheter mitral valve therapy of high-surgical-risk patients with significant MR recurrence after initial successful restrictive mitral valve annuloplasty. A total of 47 patients (age 67 ± 10 yea... Abstract
Studies in health technology and informatics, Volume 194, 1 1 2013, Pages 126-132 How to co-develop services, work, and information systems in healthcare: the daisy approach. Korpela M, Ikävalko P, Luukkonen I, Martikainen S, Palmén M, Tiihonen T, Toivanen M, Vainikainen V
Information systems in healthcare need to be designed and developed in a collaborative way. However, existing collaborative methodologies for the parallel development of healthcare work and information systems are vague and fragmented. Furthermore, they neither address people-centred healthcare nor limited-resource contexts. In this paper we introduce an emerging holistic approach, based on a unifying theoretical basis, for co-developing the services, work and information systems in healthcare.... Abstract
Cited 1 times since 2013 (0.1 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 8, Issue 9, 1 1 2013, Pages 1103-1109 How should I treat acute aortic annulus rupture during transcatheter aortic valve implantation? Debonnaire P, Van Herck PL, Katsanos S, van der Kley F, de Weger A, Palmen M, Marsan NA, Schalij MJ, Delgado V
Cited 7 times since 2012 (0.6 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 94, Issue 6, 1 1 2012, Pages 2122-2125 Implantation of a left ventricular assist device in patients with a complex apical anatomy. Palmen M, Verwey HF, Haeck ML, Holman ER, Schalij MJ, Klautz RJ
Implantation of a left ventricular assist device can be challenging in patients with an altered apical anatomy after cardiac surgery or as the result of the presence of a calcified apical aneurysm. In this paper we present 2 cases with a challenging apical anatomy and introduce a new surgical technique facilitating left ventricular assist device implantation in these patients. Abstract
Cited 12 times since 2012 (1 per year) source: EuropePMC
Current opinion in cardiology, Volume 27, Issue 5, 1 1 2012, Pages 455-464 Contemporary imaging of normal mitral valve anatomy and function. Debonnaire P, Palmen M, Marsan NA, Delgado V
Purpose of review: Mitral valve disease is highly prevalent. Accurate characterization of normal anatomy and function of the mitral valve is crucial to understand the pathophysiology of mitral valve disease. This review summarizes recent advances in noninvasive cardiac imaging to assess normal mitral valve anatomy and function and provides an overview of the clinical applications of these novel imaging techniques in the evaluation of patients with mitral valve disease. Recent findings: Echocardi... Abstract
Cited 172 times since 2011 (13.5 per year) source: Scopus
The American journal of cardiology, Volume 108, Issue 10, 17 3 2011, Pages 1470-1477 Location and severity of aortic valve calcium and implications for aortic regurgitation after transcatheter aortic valve implantation. Ewe SH, Ng AC, Schuijf JD, van der Kley F, Colli A, Palmen M, de Weger A, Marsan NA, Holman ER, de Roos A, Schalij MJ, Bax JJ, Delgado V
Location of aortic valve calcium (AVC) can be better visualized on contrast-enhanced multidetector row computed tomography. The present evaluation examined whether AVC severity and its location could influence paravalvular aortic regurgitation (AR) after transcatheter aortic valve implantation. A total of 79 patients (age 80 ± 7 years, 49% men) with preprocedural multidetector row computed tomography were included. Volumetric AVC quantification and its location were assessed. Transesophageal ech... Abstract
Cited 21 times since 2011 (1.6 per year) source: EuropePMC
Inflammatory bowel diseases, Volume 18, Issue 6, 11 2 2011, Pages 1026-1033 Strategies in maintenance for patients receiving long-term therapy (SIMPLE): a study of MMX mesalamine for the long-term maintenance of quiescent ulcerative colitis. Kane S, Katz S, Jamal MM, Safdi M, Dolin B, Solomon D, Palmen M, Barrett K
Background: This was a phase IV, multicenter, open-label, 12-14-month study to assess clinical recurrence in patients with ulcerative colitis (UC) who received maintenance treatment with MMX Multi Matrix System (MMX) mesalamine. A secondary outcome was the relationship between long-term efficacy and adherence. Methods: Patients with quiescent UC (no rectal bleeding; 0-1 bowel movements more than normal per day) were enrolled directly into a 12-month maintenance phase of the study during which th... Abstract
Cited 33 times since 2009 (2.3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 88, Issue 4, 1 1 2009, Pages 1131-1136 Open window thoracostomy treatment of empyema is accelerated by vacuum-assisted closure. Palmen M, van Breugel HN, Geskes GG, van Belle A, Swennen JM, Drijkoningen AH, van der Hulst RR, Maessen JG
Background: Recurrent thoracic empyema in the presence of residual lung tissue can be treated with an open window thoracostomy (OWT). Vacuum-assisted closure (VAC) of these large thoracic defects is a novel option. Methods: Nineteen patients with residual lung tissue received an OWT for treatment of recurrent thoracic empyema. In this retrospective case series, 8 patients (aged 58 +/- 20 years, all male) were treated conventionally, and 11 patients (aged 53 +/- 17 years, 8 male) were treated wit... Abstract
Cited 7 times since 2008 (0.4 per year) source: EuropePMC
Journal of clinical pharmacology, Volume 48, Issue 7, 19 3 2008, Pages 837-848 Population pharmacokinetic modeling of epoetin delta in pediatric patients with chronic kidney disease. Knebel W, Palmen M, Dowell JA, Gastonguay M
This analysis quantifies the population pharmacokinetics of subcutaneous and intravenous epoetin delta, an epoetin produced in a human cell line, in pediatric patients with chronic kidney disease and estimates the effects of covariate factors on epoetin delta and epoetin alfa pharmacokinetic parameters. Erythropoietin serum concentration data, taken from a phase III study conducted in 60 patients aged 1 to 17 years, were best described by a 1-compartment model with first-order absorption and eli... Abstract
Cited 10 times since 2008 (0.6 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 34, Issue 1, 1 1 2008, Pages 48-54 Long-term follow-up after repair of Ebstein's anomaly. Palmen M, de Jong PL, Klieverik LM, Venema AC, Meijboom FJ, Bogers AJ
Objective: We studied the long-term results of vertical plication repair of Ebstein's anomaly according to Carpentier. Methods: Between 1988 and 2007, 28 patients (mean age 28.8+/-15.7 years, range 4-58 years) underwent vertical plication repair of Ebstein's anomaly. At operation the anomaly was classified according to Carpentier. In three patients (11%) a cavopulmonary shunt was added at the repair on the indication of impaired right ventricular function. Results: There was no operati... Abstract
Cited 3 times since 2007 (0.2 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 32, Issue 2, 12 2 2007, Pages 274-280 New ultrasonic radiation reduces cerebral emboli during extracorporeal circulation. Sauren LD, la Meir M, Palmen M, Severdija E, van der Veen FH, Mess WH, Maessen JG
Objective: Cardiac surgery is associated with intraoperative cerebral emboli, which can result in postoperative neurological complications. A new ultrasonic transducer (EmBlocker) can be positioned on the ascending aorta and activation of the EmBlocker is expected to divert emboli to the descending aorta, thereby decreasing emboli in the cerebral arteries. In this preliminary animal study, safety and efficiency of this technology were examined. Methods: In 14 pigs (+/-70 kg), a median sternotomy... Abstract
Cited 11 times since 2006 (0.6 per year) source: EuropePMC
European journal of pharmacology, Volume 559, Issue 1, 2 1 2006, Pages 38-45 Extracellular glutamate and GABA in the ventral tegmental area of alcohol-preferring AA and alcohol-avoiding ANA rats treated repeatedly with morphine. Ojanen SP, Palmén M, Hyytiä P, Kiianmaa K
Glutamate and gamma-amino-butyric acid (GABA) have been implicated in neuronal plasticity related to behavioral sensitization. In the present study, we examined morphine-induced changes in the extracellular concentrations of glutamate and GABA in the ventral tegmental area in alcohol-preferring Alko Alcohol (AA) and alcohol-avoiding Alko Non-Alcohol (ANA) rats that have previously been shown to differ in morphine-induced sensitization. The rats were given escalating doses (5-20 mg/kg) of morphin... Abstract
Cited 206 times since 2006 (11.7 per year) source: EuropePMC
Gastroenterology, Volume 132, Issue 1, 12 2 2006, Pages 66-75; quiz 432-3 Once-daily, high-concentration MMX mesalamine in active ulcerative colitis. Kamm MA, Sandborn WJ, Gassull M, Schreiber S, Jackowski L, Butler T, Lyne A, Stephenson D, Palmen M, Joseph RE
Background & aims: SPD476 (LIALDA in the US; MEZAVANT in the EU; otherwise known as MMX mesalamine; Shire Pharmaceuticals Inc., Wayne, PA, under license from Giuliani SpA, Milan, Italy) is a novel, once-daily, high-strength (1.2 g/tablet) formulation of mesalamine, utilizing MMX Multi Matrix System (MMX) technology designed to deliver the active drug throughout the colon. We performed a double-blind, multicenter study, comparing MMX mesalamine vs placebo for the treatment of active ulcerativ... Abstract