Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
253 results
Cited 26 times since 2009 (1.7 per year) source: EuropePMC
American heart journal, Volume 158, Issue 1, 1 1 2009, Pages 40-46 Delayed improvement of right ventricular diastolic function and regression of right ventricular mass after percutaneous pulmonary valve implantation in patients with congenital heart disease. Romeih S, Kroft LJ, Bokenkamp R, Schalij MJ, Grotenhuis H, Hazekamp MG, Groenink M, de Roos A, Blom NA
Background: Percutaneous pulmonary valve implantation (PPVI) has been introduced as therapy for right ventricular (RV) to pulmonary artery conduit dysfunction in patients with congenital heart disease. It has been shown that RV systolic function improved early after PPVI. The effects of PPVI on RV diastolic function and RV hypertrophy have not yet been studied. Purpose: The objective of this study is to assess early and late changes in systolic and diastolic RV function and RV mass after PPVI. M... Abstract
Cited 11 times since 2009 (0.7 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 138, Issue 5, 26 4 2009, Pages 1167-1171 Results of surgical repair of atrioventricular septal defect with double-orifice left atrioventricular valve. Hoohenkerk GJ, Wenink AC, Schoof PH, Koolbergen DR, Bruggemans EF, Rijlaarsdam M, Hazekamp MG
Objective: The outcome of surgical correction of atrioventricular septal defect with double-orifice left atrioventricular valve has improved in recent years but is still reported to be associated with high mortality and reoperation rates. Controversy exists about the management of the accessory orifice. We evaluated our results with correction of atrioventricular septal defect with double-orifice left atrioventricular valve. Methods: Between 1975 and 2006, 21 patients underwent correction of atr... Abstract
Cited 11 times since 2009 (0.7 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 36, Issue 2, 25 4 2009, Pages 344-51; discussion 351 Pediatric tracheal reconstruction with pericardial patch and strips of autologous cartilage. Hazekamp MG, Koolbergen DR, Kersten J, Peper J, de Mol B, König-Jung A
Objective: To analyze the results of pediatric tracheal reconstruction with autologous pericardial patch and strips of cartilage. Methods: From September 2003 to February 2008 14 non-consecutive children were operated using pericardial patch augmentation of the trachea combined with external reinforcement with strips of autologous cartilage. Thin semicircular strips were fashioned from costal arch cartilage. Associated vascular rings, slings and aberrantly coursing arteries were treated first. C... Abstract
Cited 44 times since 2009 (2.9 per year) source: EuropePMC
Circulation, Volume 119, Issue 11, 9 2 2009, Pages 1467-1472 Tricuspid valve surgery in adults with a dysfunctional systemic right ventricle: repair or replace? Scherptong RW, Vliegen HW, Winter MM, Holman ER, Mulder BJ, van der Wall EE, Hazekamp MG
Background: In patients with a right ventricle (RV) in the systemic position, tricuspid valve surgery for regurgitation beyond adolescence is a subject of debate. The aim of the present study was to evaluate the complications, survival, and benefit of tricuspid surgery in adult patients with an atrium-level correction for transposition of the great arteries or congenitally corrected transposition of the great arteries. Methods and results: All adult patients (n=16; 7 men, 9 women; age 35+/-11 ye... Abstract
Cited 23 times since 2009 (1.5 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 35, Issue 4, 15 3 2009, Pages 582-7; discussion 587-8 Long-term follow-up of arterial switch operation with an emphasis on function and dimensions of left ventricle and aorta. Vandekerckhove KD, Blom NA, Lalezari S, Koolbergen DR, Rijlaarsdam ME, Hazekamp MG
Objective: To analyze size and function of aortic root and left ventricle as well as quality of life in patients 20 years after arterial switch procedure. Methods: Thirty-nine patients who underwent arterial switch operation between 1977 and 1989 were examined. Perioperative and follow-up data were analyzed. Evaluation included clinical assessment, ECG, echocardiography and quality of life questionnaire. Results: Patients had simple transposition (24), transposition with ventricle septal defect... Abstract
Cited 89 times since 2008 (5.7 per year) source: EuropePMC
European journal of immunology, Volume 38, Issue 9, 1 1 2008, Pages 2389-2400 Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B. Nagasawa M, Schmidlin H, Hazekamp MG, Schotte R, Blom B
Plasmacytoid dendritic cells (pDC) are central players in the innate and adaptive immune response against viral infections. The molecular mechanism that underlies pDC development from progenitor cells is only beginning to be elucidated. Previously, we reported that the Ets factor Spi-B and the inhibitors of DNA binding protein 2 (Id2) or Id3, which antagonize E-protein activity, are crucially involved in promoting or impairing pDC development, respectively. Here we show that the basic helix-loop... Abstract
Cited 18 times since 2008 (1.1 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 85, Issue 5, 1 1 2008, Pages 1686-1689 28 years' experience with transatrial-transpulmonary repair of atrioventricular septal defect with tetralogy of Fallot. Hoohenkerk GJ, Schoof PH, Bruggemans EF, Rijlaarsdam M, Hazekamp MG
Background: The outcome of surgical correction of atrioventricular septal defect and tetralogy of Fallot has improved in recent years but is still reported to be associated with high mortality. Controversy exists about the need of a right ventriculotomy or a right ventricular to pulmonary artery conduit. The purpose of this study was to evaluate our results of atrioventricular septal defect and tetralogy of Fallot repair by transatrial-transpulmonary approaches. Methods: Between 1979 and 2007, 2... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 7, Issue 3, 28 4 2008, Pages 517-518 Early atrial septal defect surgery due to a bronchogenic cyst causing congestive heart failure by left atrium compression. Mosquera VX, Rijlaarsdam M, Filippini L, Hazekamp MG
We report on an uncommon case of a 10-month-old patient who required early surgical closure of an ostium secumdum atrial septal defect due to the concomitant presence of a big subcarinal bronchogenic cyst compressing the left atrium and, therefore, increasing the left-to-right shunt. It led to refractory congestive heart failure symptoms, establishing thereby an earlier indication of surgical treatment. Abstract
Cited 1 times since 2008 (0.1 per year) source: EuropePMC
Multimedia manual of cardiothoracic surgery : MMCTS, Volume 2008, Issue 915, 1 1 2008, Pages mmcts.2006.002329 Surgery for supravalvular aortic stenosis - the three-patch technique. Arnáiz E, Koolbergen D, Adsuar A, Hazekamp MG
The objective of this paper is to describe the three-patch technique for repair of supravalvular aortic stenosis (SVAS). Supravalvular aortic stenosis is a rare malformation as a result of an abnormal thickening of the aortic wall. SVAS may present in two forms: a localized form (affecting only the aortic sinotubular junction) and a diffuse form, where the aortic arch and its side branches are also affected. Since 1960, multiple surgical techniques have been described with the aim of relieving t... Abstract
Cited 1 times since 2007 (0.1 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 151, Issue 46, 1 1 2007, Pages 2580-2585 [Percutaneous implantation of a pulmonary valve in 3 children with surgically corrected cardiac anomalies]. Bökenkamp R, Hazekamp MG, Schalij MJ, Clur SA, Ottenkamp J, Blom NA
An 11-year-old girl, a 15-year-old boy and a 12-year-old girl all underwent percutaneous implantation of a Melody pulmonary valve prosthesis to replace a stenotic and insufficient homograft in the pulmonary artery. Preoperatively, 2 of the children suffered from fatigue and dyspnoea on exertion The homografts had been implanted between the ages of 1-2, to establish surgical continuity between the right ventricle and the pulmonary artery. The anomalies were tetralogy of Fallot, pulmonary atresia... Abstract
Cited 15 times since 2007 (0.9 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 84, Issue 2, 1 1 2007, Pages 599-605 Right ventricular outflow tract reconstruction with the bovine jugular vein graft: 5 years' experience with 133 patients. Sekarski N, van Meir H, Rijlaarsdam ME, Schoof PH, Koolbergen DR, Hruda J, von Segesser LK, Meijboom EJ, Hazekamp MG
Background: We analyzed the results in two centers of using bovine jugular vein graft for right ventricular outflow tract reconstruction. Methods: From April 1999 to July 2005, 133 children with a median age of 30.9 months (range, 4 days to 19 years) underwent graft implantation. Echocardiography was performed during follow-up and retrospectively reviewed. Results: Nongraft-related early mortality occurred in 8 patients. Late mortality occurred in 11 patients, 2 late deaths were graft related (e... Abstract
Cited 298 times since 2007 (17.7 per year) source: EuropePMC
Circulation, Volume 116, Issue 5, 9 2 2007, Pages 545-551 Preoperative thresholds for pulmonary valve replacement in patients with corrected tetralogy of Fallot using cardiovascular magnetic resonance. Oosterhof T, van Straten A, Vliegen HW, Meijboom FJ, van Dijk AP, Spijkerboer AM, Bouma BJ, Zwinderman AH, Hazekamp MG, de Roos A, Mulder BJ
Background: To facilitate the optimal timing of pulmonary valve replacement, we analyzed preoperative thresholds of right ventricular (RV) volumes above which no decrease or normalization of RV size takes place after surgery. Methods and results: Between 1993 and 2006, 71 adult patients with corrected tetralogy of Fallot underwent pulmonary valve replacement in a nationwide, prospective follow-up study. Patients were evaluated with cardiovascular magnetic resonance both preoperatively and postop... Abstract
Cited 10 times since 2007 (0.6 per year) source: EuropePMC
International journal of cardiology, Volume 124, Issue 3, 11 2 2007, Pages 301-306 Pulmonary valve replacement in tetralogy of Fallot improves the repolarization. Hooft van Huysduynen B, Henkens IR, Swenne CA, Oosterhof T, Draisma HH, Maan AC, Hazekamp MG, de Roos A, Schalij MJ, van der Wall EE, Vliegen HW
Objective: To assess the effect of pulmonary valve replacement (PVR) on the repolarization of patients with tetralogy of Fallot. Background: Pulmonary valve regurgitation may cause right ventricular failure in adult patients with Fallot's tetralogy. In these patients, prolonged depolarization and disturbed repolarization are associated with ventricular arrhythmias and sudden cardiac death. Methods: Thirty Fallot patients (age 32+/-9 years, 19 male) eligible for PVR were studied with cardiac... Abstract
Cited 51 times since 2007 (3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 83, Issue 3, 1 1 2007, Pages 907-911 Predicting outcome of pulmonary valve replacement in adult tetralogy of Fallot patients. Henkens IR, van Straten A, Schalij MJ, Hazekamp MG, de Roos A, van der Wall EE, Vliegen HW
Background: Predicting changes in right ventricular (RV) size and function after pulmonary valve replacement (PVR) is important for timely reintervention in adult tetralogy of Fallot patients. Methods: We analyzed the influence of pulmonary regurgitation severity and RV size and function before PVR on the outcome of RV size and function after PVR in 27 adult Fallot patients who had cardiac magnetic resonance imaging before and after PVR. RV dimensions were indexed for body surface area. Results:... Abstract
Cited 22 times since 2007 (1.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 93, Issue 12, 3 1 2007, Pages 1604-1608 Right ventricular hypertrophy and diastolic dysfunction in arterial switch patients without pulmonary artery stenosis. Grotenhuis HB, Kroft LJ, van Elderen SG, Westenberg JJ, Doornbos J, Hazekamp MG, Vliegen HW, Ottenkamp J, de Roos A
Objective: To assess pulmonary flow dynamics and right ventricular (RV) function in patients without significant anatomical narrowing of the pulmonary arteries late after the arterial switch operation (ASO) by using magnetic resonance imaging (MRI). Methods: 17 patients (mean (SD), 16.5 (3.6) years after ASO) and 17 matched healthy subjects were included. MRI was used to assess flow across the pulmonary trunk, RV systolic and diastolic function, and RV mass. Results: Increased peak flow velocity... Abstract
Cited 26 times since 2006 (1.5 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 132, Issue 6, 1 1 2006, Pages 1426-1432 Degeneration of the pulmonary autograft: an explant study. Schoof PH, Takkenberg JJ, van Suylen RJ, Zondervan PE, Hazekamp MG, Dion RA, Bogers AJ
Objective: We sought to determine the histologic features of pulmonary autografts explanted after the Ross operation. Methods: Histologic sections of 30 explanted autografts and 8 normal heart valves were compared and semiquantitatively scored by a blinded cardiovascular pathologist. Results: Pulmonary autografts (n = 30) were explanted on average 6.1 +/- 0.6 years (median, 6.6 years; range, 0.1-11.7 years) after the Ross operation (n = 28) or removed at autopsy (n = 2). Twelve (43%) of the pati... Abstract
Cited 3 times since 2006 (0.2 per year) source: EuropePMC
International journal of cardiology, Volume 121, Issue 1, 28 4 2006, Pages 123-124 Preoperative determinants of recovery time in adult Fallot patients after late pulmonary valve replacement. Henkens IR, van Straten A, Hazekamp MG, Schalij MJ, de Roos A, van der Wall EE, Vliegen HW
Cited 20 times since 2006 (1.1 per year) source: EuropePMC
American heart journal, Volume 152, Issue 5, 1 1 2006, Pages 975.e1-8 Aortic root dysfunctioning and its effect on left ventricular function in Ross procedure patients assessed with magnetic resonance imaging. Grotenhuis HB, Westenberg JJ, Doornbos J, Kroft LJ, Schoof PH, Hazekamp MG, Vliegen HW, Ottenkamp J, de Roos A
Background: This study evaluated the diameters and distensibility of the aortic root as well as the degree of aortic regurgitation (AR) and its effect on left ventricular (LV) function in patients 8.2 +/- 3.1 years after they underwent the Ross procedure, with a comparison of these parameters between patients and matched healthy subjects. Methods: Eighteen Ross procedure patients (16 male patients, age [mean +/- SD] 19.2 +/- 3.8 years) and 18 matched healthy subjects (16 male patients, age [mean... Abstract
Cited 2 times since 2006 (0.1 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 150, Issue 35, 1 1 2006, Pages 1930-1935 [Favourable results with surgical treatment in 43 children with hypoplastic left-heart syndrome or similar disorders, 1999-2005]. Hazekamp MG, Rijlaarsdam ME, Schoof PH, Wald AA, Blom NA, Ottenkamp J
Objective: To describe the results of surgical treatment of hypoplastic left-heart syndrome (HLHS) and HLHS-like disorders in the Amsterdam-Leiden Centre for Congenital Heart Disease, the Netherlands. Design: Retrospective, descriptive. Method: Data were collected on 43 neonates with HLHS or similar disorders who underwent surgical treatment between December 1999 and December 2005. HLHS was present in 37 patients and 6 had disorders similar to HLHS (unbalanced atrioventricular septal defect, tru... Abstract
Cited 14 times since 2006 (0.8 per year) source: EuropePMC
Pediatric cardiology, Volume 27, Issue 5, 23 4 2006, Pages 552-556 Surgical repair of aortopulmonary window: thirty-seven years of experience. Jansen C, Hruda J, Rammeloo L, Ottenkamp J, Hazekamp MG
An aortopulmonary window (APW) is a communication between the ascending aorta and the pulmonary trunk in the presence of two separate semilunar valves. In order to increase our understanding about the surgical management of this rare lesion and its long-term results, we describe our experience over a 37-year period. Between 1968 and 2005, 18 patients were diagnosed with APW. Seventeen underwent surgical correction. Age at operation ranged from 22 days to 22 years (median, 0.20 years). Follow-up... Abstract