Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
253 results
Cited 14 times since 2012 (1.1 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 144, Issue 6, 8 2 2012, Pages 1315-1322 Disturbed myocardial connexin 43 and N-cadherin expressions in hypoplastic left heart syndrome and borderline left ventricle. Mahtab EA, Gittenberger-de Groot AC, Vicente-Steijn R, Lie-Venema H, Rijlaarsdam ME, Hazekamp MG, Bartelings MM
Objectives: Borderline left ventricle is the left ventricular morphology at the favorable end of the hypoplastic left heart syndrome. In contrast to the severe end, it is suitable for biventricular repair. Wondering whether it is possible to identify cases suitable for biventricular repair from a developmental viewpoint, we investigated the myocardial histology of borderline and severely hypoplastic left ventricles. Methods: Postmortem specimens of neonatal, unoperated human hearts with severe h... Abstract
Cited 3 times since 2012 (0.2 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 42, Issue 1, 26 4 2012, Pages 50-55 Effect of age on exercise capacity and cardiac reserve in patients with pulmonary atresia with intact ventricular septum after biventricular repair. Romeih S, Groenink M, van der Plas MN, Spijkerboer AM, Hazekamp MG, Luijnenburg S, Mulder BJ, Blom NA
Objectives: In patients with pulmonary atresia with intact ventricular septum (PAIVS), biventricular repair is considered to be the optimal treatment option in the absence of significant right ventricular (RV) hypoplasia. However, long-term clinical outcome studies are limited. We evaluated exercise capacity and cardiac function during pharmacological stress in children and young adults with PAIVS after biventricular repair. Methods: Ten PAIVS patients after biventricular repair, with a median a... Abstract
Cited 16 times since 2012 (1.3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 93, Issue 3, 23 4 2012, Pages 849-855 Long-term results of reoperation for left atrioventricular valve regurgitation after correction of atrioventricular septal defects. Hoohenkerk GJ, Bruggemans EF, Koolbergen DR, Rijlaarsdam ME, Hazekamp MG
Background: Long-term results of reoperation for left atrioventricular valve regurgitation (LAVVR) after previous correction of atrioventricular septal defect (AVSD) are scarce. We evaluated long-term outcome of reoperation for LAVVR and identified risk factors for reoperation. Methods: Between December 1976 and July 2006, 45 of 312 patients with correction of different AVSDs underwent reoperation for LAVVR. The cohort of 267 patients who did not need reoperation for LAVVR allowed for the identi... Abstract
Cited 45 times since 2011 (3.6 per year) source: EuropePMC
Circulation, Volume 124, Issue 20, 10 2 2011, Pages 2195-2201 Surgery in adults with congenital heart disease. Zomer AC, Verheugt CL, Vaartjes I, Uiterwaal CS, Langemeijer MM, Koolbergen DR, Hazekamp MG, van Melle JP, Konings TC, Bellersen L, Grobbee DE, Mulder BJ
Background: A significant proportion of patients with congenital heart disease require surgery in adulthood. We aimed to give an overview of the prevalence, distribution, and outcome of cardiovascular surgery for congenital heart disease. We specifically questioned whether the effects of surgical treatment on subsequent long-term survival depend on sex. Methods and results: From the Dutch Congenital Corvitia (CONCOR) registry for adults with congenital heart disease, we identified 10 300 patient... Abstract
Cited 5 times since 2011 (0.4 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 19, Issue 10, 1 1 2011, Pages 432-435 Per-operative stent placement in the right pulmonary artery; a hybrid technique for the management of pulmonary artery branch stenosis at the time of pulmonary valve replacement in adult Fallot patients. Windhausen F, Boekholdt SM, Bouma BJ, Groenink M, Backx AP, de Winter RJ, Mulder BJ, Hazekamp MG, Koolbergen DR
After having undergone surgical correction at an early age, many patients with tetralogy of Fallot develop long-term complications including progressive pulmonary regurgitation and peripheral pulmonary stenosis. A high percentage of these patients need to undergo a second operation in their adolescence or early adulthood. If simultaneous treatment of both pulmonary regurgitation and peripheral pulmonary stenosis is warranted, a complete surgical approach has several disadvantages. We describe fo... Abstract
Cited 8 times since 2011 (0.6 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 143, Issue 3, 9 2 2011, Pages 569-575 Exercise capacity and cardiac reserve in children and adolescents with corrected pulmonary atresia with intact ventricular septum after univentricular palliation and biventricular repair. Romeih S, Groenink M, Roest AA, van der Plas MN, Hazekamp MG, Mulder BJ, Blom NA
Objective: Management of pulmonary atresia with intact ventricular septum is challenging and depends on the severity of right ventricular hypoplasia. Clinical outcomes of biventricular repair seem favorable to univentricular palliation, but data on superiority of biventricular repair regarding exercise capacity are conflicting. We investigated the response to physical and pharmacologic stress in patients with surgically corrected pulmonary atresia with intact ventricular septum. Methods: Sixteen... Abstract
Cited 39 times since 2011 (3.1 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 92, Issue 3, 1 1 2011, Pages 973-979 Thirty-year experience with the arterial switch operation. Lalezari S, Bruggemans EF, Blom NA, Hazekamp MG
Background: We evaluated the results of the arterial switch operation (ASO) being performed at our institution for more than 30 years and identified risk factors for mortality and reoperation. Methods: Clinical outcome of 332 consecutive patients with transposition of the great arteries undergoing ASO was retrospectively analyzed, using surgical reports, medical charts, and latest follow-up echocardiography. Statistical analysis was performed using the Kaplan-Meier method and univariable and mul... Abstract
Cited 24 times since 2011 (1.9 per year) source: EuropePMC
Intensive care medicine, Volume 37, Issue 10, 30 5 2011, Pages 1656-1663 Ventilator-associated pneumonia in children after cardiac surgery in The Netherlands. Roeleveld PP, Guijt D, Kuijper EJ, Hazekamp MG, de Wilde RB, de Jonge E
Purpose: We conducted a retrospective cohort study in an academic tertiary care center to characterize ventilator-associated pneumonia (VAP) in pediatric patients after cardiac surgery in The Netherlands. Methods: All patients following cardiac surgery and mechanically ventilated for ≥24 h were included. The primary outcome was development of VAP. Secondary outcomes were duration of mechanical ventilation and length of ICU stay. Results: A total of 125 patients were enrolled. Their mean age was... Abstract
The Annals of thoracic surgery, Volume 92, Issue 1, 1 1 2011, Pages 166 Invited commentary. Hazekamp MG
Cited 26 times since 2011 (2 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 28, Issue 4, 3 1 2011, Pages 755-762 Right ventricular function declines after cardiac surgery in adult patients with congenital heart disease. Schuuring MJ, Bolmers PP, Mulder BJ, de Bruin-Bon RA, Koolbergen DR, Hazekamp MG, Lagrand WK, De Hert SG, de Beaumont EM, Bouma BJ
Right ventricular function (RVF) is often selectively declined after coronary artery bypass graft surgery. In adult patients with congenital heart disease (CHD) the incidence and persistence of declined RVF after cardiac surgery is unknown. The current study aimed to describe RVF after cardiac surgery in these patients. Adult CHD patients operated between January 2008 and December 2009 in the Academic Medical Centre in Amsterdam were studied. Clinical characteristics, laboratory tests, surgical... Abstract
Cited 3 times since 2011 (0.2 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 13, Issue 3, 1 1 2011, Pages 339-340 Neo-coarctation after the arterial switch operation. Lalezari S, Gittenberger-de Groot AC, Blom NA, Hazekamp MG
Neo-coarctation following arterial switch operation (ASO) for transposition of the great arteries (TGA) is a complication that is not regularly described, but may occur. We describe five patients who developed a neo-coarctation after operation. They were diagnosed with TGA, either with or without ventricular septal defect without signs or symptoms of a coarctation. Except for one patient, all patients were reoperated for a neo-coarctation within one year after the ASO. Several explanations are d... Abstract
Cited 1 times since 2011 (0.1 per year) source: EuropePMC
Cardiology in the young, Volume 21, Issue 2, 1 1 2011 Assessment of proximal right coronary artery and cardiac dimensions with low-dose volumetric computed tomographic angiography in a child. Roest AA, Hazekamp MG, Kroft LJ
Cited 6 times since 2011 (0.5 per year) source: EuropePMC
Circulation. Cardiovascular interventions, Volume 4, Issue 1, 1 1 2011, Pages 112-113 Percutaneous tricuspid valve implantation in a Fontan patient with congestive heart failure and protein-losing enteropathy. Straver B, Wagenaar LJ, Blom NA, Mulder BJ, Bouma BJ, Hazekamp MG, de Winter RJ
Cited 42 times since 2010 (3.1 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 90, Issue 5, 1 1 2010, Pages 1554-1561 More than 30 years' experience with surgical correction of atrioventricular septal defects. Hoohenkerk GJ, Bruggemans EF, Rijlaarsdam M, Schoof PH, Koolbergen DR, Hazekamp MG
Background: Outcome of surgical correction of atrioventricular septal defects (AVSD) still varies despite enhanced results. We reviewed our 30-year experience with AVSD repair and identified risk factors for mortality and reoperation. Methods: Between 1975 and 2006, 312 patients underwent surgery for complete AVSD (n = 209; 67.0%), partial AVSD (n = 76; 24.4%), or intermediate AVSD (n = 27; 8.6%). Mean age was 2.4 ± 3.9 years; 142 patients (45.5%) were younger than 6 months. Follow-up was 99.0%... Abstract
Cited 49 times since 2010 (3.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 56, Issue 18, 1 1 2010, Pages 1486-1492 Follow-up after pulmonary valve replacement in adults with tetralogy of Fallot: association between QRS duration and outcome. Scherptong RW, Hazekamp MG, Mulder BJ, Wijers O, Swenne CA, van der Wall EE, Schalij MJ, Vliegen HW
Objectives: The aim of this study was to analyze whether QRS duration, before and after pulmonary valve replacement (PVR), is related to long-term outcome in patients with tetralogy of Fallot (TOF). Background: Key factors that determine outcome after PVR in adult TOF patients are largely unknown. Recognition of such factors assists the identification of patients at increased risk of adverse events. Methods: Adults who previously underwent total correction for TOF (n=90; age 31.4±10.3 years) and... Abstract
Cited 37 times since 2010 (2.7 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 5, 23 4 2010, Pages 723-729 Relation of left ventricular twist and global strain with right ventricular dysfunction in patients after operative "correction" of tetralogy of fallot. van der Hulst AE, Delgado V, Holman ER, Kroft LJ, de Roos A, Hazekamp MG, Blom NA, Bax JJ, Roest AA
In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse ventricular-ventricular interactions. However, the mechanism that links RV dysfunction to LV dysfunction remains unclear. In this prospective study, 32 patients with cToF and 19 controls were enrolled. With cardiac magnetic resonance imaging, biventricular ejection fractions were assessed. Using 2-dimensional speckle tracking, globa... Abstract
Cited 31 times since 2010 (2.2 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 38, Issue 6, 13 2 2010, Pages 699-706 Surgery for transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstruction: European Congenital Heart Surgeons Association multicentre study. Hazekamp MG, Gomez AA, Koolbergen DR, Hraska V, Metras DR, Mattila IP, Daenen W, Berggren HE, Rubay JE, Stellin G, European Congenital Heart Surgeons Association
Objectives: Optimal surgical management for patients with transposition of the great arteries (TGA), ventricular septal defect (VSD) and left ventricular outflow obstruction (LVOTO) remains controversial. Although the Rastelli operation has been the most widely performed surgical procedure during the past decades, several studies have shown its suboptimal long-term prognosis. Other operations have been developed to improve results. This study was performed to compare the outcomes of the differen... Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 37, Issue 6, 12 2 2010, Pages 1259-1263 Left atrial isomerism: biventricular repair. Vodiskar J, Clur SA, Hruda J, Bokenkamp R, Hazekamp MG
Objective: Biventricular repair of hearts with left atrial isomerism often necessitates complex atrial and ventricular baffle procedures. We analysed our experience with an accent on baffle techniques. Methods: From 1997 until 2008, 12 patients (four male) with left atrial isomerism received biventricular repair. Their median age at surgery was 9 (range: 1-24) months. Four patients had dextrocardia. Nine patients presented with left superior vena cava, three with absent right superior vena cava,... Abstract
Cited 15 times since 2009 (1 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 88, Issue 4, 1 1 2009, Pages 1300-1305 The outflow tract in transposition of the great arteries: an anatomic and morphologic study. Lalezari S, Mahtab EA, Bartelings MM, Wisse LJ, Hazekamp MG, Gittenberger-de Groot AC
Background: Neoaortic root dilatation is observed after the arterial switch operation for transposition of the great arteries. Although structural differences in the vessel wall of these patients may be of influence, we hypothesize that a histomorphologic difference in composition and embedding of the fibrous annulus in transposition of the great arteries may play a role in neoaortic root dilatation. Methods: Two normal human hearts and two unoperated human hearts with transposition of the great... Abstract
Cited 6 times since 2009 (0.4 per year) source: EuropePMC
Expert review of cardiovascular therapy, Volume 7, Issue 9, 1 1 2009, Pages 1117-1122 Opportunities in pulmonary valve replacement. Oosterhof T, Hazekamp MG, Mulder BJ
Pulmonary regurgitation is the most important residual lesion after initial surgical correction for pulmonary (sub)valvular stenosis in the early life of patients with tetralogy of Fallot or isolated pulmonary stenosis. Symptomatic or asymptomatic patients with severe right ventricular dilatation due to pulmonary regurgitation may benefit from pulmonary valve replacement. Surgery is ideally performed before the right ventricle becomes irreversibly damaged as a result of longstanding volume overl... Abstract