9 results
BMC pulmonary medicine,
Volume 23, Issue 1, 20 3 2023, Pages 134
Diagnostic performance of eNose technology in COVID-19 patients after hospitalization.
van Raaij BFM, Veltman JD, Hameete JF, Stöger JL, Geelhoed JJM
Background: Volatile organic compounds (VOCs) produced by human cells reflect metabolic and pathophysiological processes which can be detected with the use of electronic nose (eNose) technology. Analysis of exhaled breath may potentially play an important role in diagnosing COVID-19 and stratification of patients based on pulmonary function or chest CT. Methods: Breath profiles of COVID-19 patients were collected with an eNose device (SpiroNose) 3 months after discharge from the Leiden Universit...
Abstract
American heart journal plus : cardiology research and practice,
Volume 27, 23 4 2023, Pages 100280
Coronary calcium score in COVID-19 survivors: Association with cardiac injury and cardiac function after 6 weeks.
Groen RA, de Graaf MA, Stöger JL, van Dijkman PRM, Jukema JW, Schalij MJ, Geelhoed JJM, Antoni ML
Aims: Cardiac manifestations are common in COVID-19, often elevated serum troponin levels or myocardial dysfunction on trans-thoracic echocardiography (TTE) is observed. Both parameters are associated with increased in-hospital mortality. Possibly, subclinical coronary atherosclerosis plays a role, of which severity can be assessed by calculating the coronary artery calcium (CAC) score. This study aims to determine the relation between coronary atherosclerosis and cardiac manifestations in COVID...
Abstract
Respiratory medicine and research,
Volume 82, 17 3 2022, Pages 100973
Fibrotic-like abnormalities notably prevalent one year after hospitalization with COVID-19.
van Raaij BFM, Stöger JL, Hinnen C, Penfornis KM, de Jong CMM, Klok FA, Roukens AHE, Veldhuijzen DS, Arbous MS, Noordam R, Marges ER, Geelhoed JJM
Background: We investigated whether COVID-19 leads to persistent impaired pulmonary function, fibrotic-like abnormalities or psychological symptoms 12 months after discharge and whether severely ill patients (ICU admission) recover differently than moderately ill patients. Methods: This single-centre cohort study followed adult COVID-19 survivors for a period of one year after discharge. Patients underwent pulmonary function tests 6 weeks, 3 months and 12 months after discharge and were psycholo...
Abstract
JMIR formative research,
Volume 6, Issue 7, 28 4 2022, Pages e38263
COVID-box Experiences of Patients and Health Care Professionals (COVID-box Project): Single-Center, Retrospective, Observational Study.
Dirikgil E, Brons K, Duindam M, Groeneveld GH, Geelhoed JJM, Heringhaus C, van der Boog PJM, Rabelink TJ, Bos WJW, Chavannes NH, Atsma DE, Teng YKO
Background: During the COVID-19 pandemic, several home monitoring programs have described the success of reducing hospital admissions, but only a few studies have investigated the experiences of patients and health care professionals. Objective: The objective of our study was to determine patients' and health care professionals' experiences and satisfaction with employing the COVID-box. Methods: In this single-center, retrospective, observational study, patients and health care profess...
Abstract
Cited 2 times since 2022 (1.8 per year)
source: EuropePMC
Respirology (Carlton, Vic.),
Volume 27, Issue 7, 19 3 2022, Pages 501-509
Home monitoring of lung function, symptoms and quality of life after admission with COVID-19 infection: The HOMECOMIN' study.
Nakshbandi G, Moor CC, Nossent EJ, Geelhoed JJM, Baart SJ, Boerrigter BG, Aerts JGJV, Nijman SFM, Santema HY, Hellemons ME, Wijsenbeek MS
Background and objective: To develop targeted and efficient follow-up programmes for patients hospitalized with coronavirus disease 2019 (COVID-19), structured and detailed insights in recovery trajectory are required. We aimed to gain detailed insights in long-term recovery after COVID-19 infection, using an online home monitoring programme including home spirometry. Moreover, we evaluated patient experiences with the home monitoring programme. Methods: In this prospective multicentre study, we...
Abstract
Cited 43 times since 2021 (22 per year)
source: EuropePMC
The Lancet. Respiratory medicine,
Volume 9, Issue 9, 18 3 2021, Pages 957-968
Imatinib in patients with severe COVID-19: a randomised, double-blind, placebo-controlled, clinical trial.
Aman J, Duijvelaar E, Botros L, Kianzad A, Schippers JR, Smeele PJ, Azhang S, Bartelink IH, Bayoumy AA, Bet PM, Boersma W, Bonta PI, Boomars KAT, Bos LDJ, van Bragt JJMH, Braunstahl GJ, Celant LR, Eger KAB, Geelhoed JJM, van Glabbeek YLE, Grotjohan HP, Hagens LA, Happe CM, Hazes BD, Heunks LMA, van den Heuvel M, Hoefsloot W, Hoek RJA, Hoekstra R, Hofstee HMA, Juffermans NP, Kemper EM, Kos R, Kunst PWA, Lammers A, van der Lee I, van der Lee EL, Maitland-van der Zee AH, Mau Asam PFM, Mieras A, Muller M, Neefjes ECW, Nossent EJ, Oswald LMA, Overbeek MJ, Pamplona CC, Paternotte N, Pronk N, de Raaf MA, van Raaij BFM, Reijrink M, Schultz MJ, Serpa Neto A, Slob EMA, Smeenk FWJM, Smit MR, Smits AJ, Stalenhoef JE, Tuinman PR, Vanhove ALEM, Wessels JN, van Wezenbeek JCC, Vonk Noordegraaf A, de Man FS, Bogaard HJ
Background: The major complication of COVID-19 is hypoxaemic respiratory failure from capillary leak and alveolar oedema. Experimental and early clinical data suggest that the tyrosine-kinase inhibitor imatinib reverses pulmonary capillary leak. Methods: This randomised, double-blind, placebo-controlled, clinical trial was done at 13 academic and non-academic teaching hospitals in the Netherlands. Hospitalised patients (aged ≥18 years) with COVID-19, as confirmed by an RT-PCR test for SARS-CoV-2...
Abstract
Cited 33 times since 2021 (14.1 per year)
source: Scopus
EClinicalMedicine,
Volume 32, 28 4 2021, Pages 100731
Short-term outpatient follow-up of COVID-19 patients: A multidisciplinary approach.
de Graaf MA, Antoni ML, Ter Kuile MM, Arbous MS, Duinisveld AJF, Feltkamp MCW, Groeneveld GH, Hinnen SCH, Janssen VR, Lijfering WM, Omara S, Postmus PE, Ramai SRS, Rius-Ottenheim N, Schalij MJ, Schiemanck SK, Smid L, Stöger JL, Visser LG, de Vries JJC, Wijngaarden MA, Geelhoed JJM, Roukens AHE
Background: Short-term follow-up of COVID-19 patients reveals pulmonary dysfunction, myocardial damage and severe psychological distress. Little is known of the burden of these sequelae, and there are no clear recommendations for follow-up of COVID-19 patients.In this multi-disciplinary evaluation, cardiopulmonary function and psychological impairment after hospitalization for COVID-19 are mapped. Methods: We evaluated patients at our outpatient clinic 6 weeks after discharge. Cardiopulmonary fu...
Abstract
Cited 160 times since 2020 (54.9 per year)
source: EuropePMC
The European respiratory journal,
Volume 56, Issue 1, 2 1 2020, Pages 2001494
The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19.
Klok FA, Boon GJAM, Barco S, Endres M, Geelhoed JJM, Knauss S, Rezek SA, Spruit MA, Vehreschild J, Siegerink B
Abstract
Cited 29 times since 2018 (5.8 per year)
source: EuropePMC
Respiratory research,
Volume 19, Issue 1, 29 5 2018, Pages 105
A home monitoring program including real-time wireless home spirometry in idiopathic pulmonary fibrosis: a pilot study on experiences and barriers.
Moor CC, Wapenaar M, Miedema JR, Geelhoed JJM, Chandoesing PP, Wijsenbeek MS
In idiopathic pulmonary fibrosis (IPF), home monitoring experiences are limited, not yet real-time available nor implemented in daily care. We evaluated feasibility and potential barriers of a new home monitoring program with real-time wireless home spirometry in IPF. Ten patients with IPF were asked to test this home monitoring program, including daily home spirometry, for four weeks. Measurements of home and hospital spirometry showed good agreement. All patients considered real-time wireless...
Abstract
