Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
95 results
Cited 27 times since 2009 (1.8 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 3, 17 3 2009, Pages 249-257 Long-term improvement in left ventricular strain after successful catheter ablation for atrial fibrillation in patients with preserved left ventricular systolic function. Tops LF, Den Uijl DW, Delgado V, Marsan NA, Zeppenfeld K, Holman E, van der Wall EE, Schalij MJ, Bax JJ
Background: The effect of successful catheter ablation on left ventricular (LV) strain in patients with preserved LV systolic function is unknown. The aim of the present study was to assess the long-term effects of catheter ablation for atrial fibrillation (AF) on LV strain and strain rate in patients with preserved LV ejection fraction. Methods and results: In 78 patients undergoing catheter ablation for AF, speckle tracking strain imaging was performed to assess LV strain in 3 directions (radi... Abstract
JACC. Cardiovascular imaging, Volume 2, Issue 4, 1 1 2009, Pages 498-510 The year in imaging related to electrophysiology. Tops LF, Bax JJ
Cited 12 times since 2009 (0.8 per year) source: EuropePMC
Echocardiography (Mount Kisco, N.Y.), Volume 26, Issue 3, 1 1 2009, Pages 315-323 The role of speckle tracking strain imaging in cardiac pacing. Tops LF, Delgado V, Bax JJ
In recent years, concerns have been raised about possible harmful effects of long-term right ventricular (RV) apical pacing. These detrimental effects may be related to changes in left ventricular (LV) mechanics during RV apical pacing. As a consequence, alternative RV pacing sites have been proposed, and in selected patients an upgrade from RV to biventricular pacing may be considered. Novel two-dimensional (2D) speckle tracking strain imaging allows detailed evaluation of LV mechanics, includi... Abstract
Cited 33 times since 2009 (2.2 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 2, Issue 2, 1 1 2009, Pages e12-3 Successful deployment of a transcatheter aortic valve in bicuspid aortic stenosis: role of imaging with multislice computed tomography. Delgado V, Tops LF, Schuijf JD, van der Kley F, van de Veire NR, Schalij MJ, Bax JJ
Cited 79 times since 2009 (5.2 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 2, 18 3 2009, Pages 135-145 Acute effects of right ventricular apical pacing on left ventricular synchrony and mechanics. Delgado V, Tops LF, Trines SA, Zeppenfeld K, Marsan NA, Bertini M, Holman ER, Schalij MJ, Bax JJ
Background: Chronic right ventricular (RV) apical pacing has a detrimental effect on left ventricular (LV) function. However, the acute effects of RV apical pacing on LV mechanics remain unclear. The purpose of the study was to assess the acute impact of RV apical pacing on global LV function, evaluating LV contraction synchrony and LV shortening and twist, using 2D speckle-tracking strain imaging. Methods and results: A group of 25 patients with structural normal hearts referred for electrophys... Abstract
Cited 3 times since 2009 (0.2 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 2, Issue 2, 1 1 2009, Pages 226-230 Cardiac resynchronization therapy devices guided by imaging technology. Krishnan SC, Tops LF, Bax JJ
Cited 48 times since 2009 (3.1 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 2, Issue 2, 26 4 2009, Pages 100-106 Prevalence of coronary artery disease assessed by multislice computed tomography coronary angiography in patients with paroxysmal or persistent atrial fibrillation. Nucifora G, Schuijf JD, Tops LF, van Werkhoven JM, Kajander S, Jukema JW, Schreur JH, Heijenbrok MW, Trines SA, Gaemperli O, Turta O, Kaufmann PA, Knuuti J, Schalij MJ, Bax JJ
Background: Although atrial fibrillation (AF) has been linked to underlying coronary artery disease (CAD), data supporting this association have been based on ECG and clinical history for the definition of CAD rather than direct visualization of atherosclerosis. Methods and results: The prevalence of CAD among patients with paroxysmal or persistent AF and without history of CAD was evaluated using multislice computed tomography. Multislice computed tomography was performed in 150 patients with A... Abstract
Cited 15 times since 2008 (1 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 1, Issue 6, 18 3 2008, Pages 729-738 Magnetic resonance cardiac vein imaging: relation to mitral valve annulus and left circumflex coronary artery. Chiribiri A, Kelle S, Köhler U, Tops LF, Schnackenburg B, Bonamini R, Bax JJ, Fleck E, Nagel E
Objectives: To evaluate in vivo anatomical relationships between the coronary sinus-great cardiac vein (CS-GCV), the mitral valve annulus (MVA), and left circumflex coronary artery (LCX) with cardiovascular magnetic resonance. Background: The CS-GCV has become an anatomical structure of interest because it provides a way of access to the heart for a number of interventional procedures. Previous reports demonstrate that the postulated close anatomical proximity of the CS-GCV to the MVA does not a... Abstract
Cited 13 times since 2008 (0.8 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 10 Suppl 3, 1 1 2008, Pages iii48-56 Image integration in catheter ablation of atrial fibrillation. Tops LF, Schalij MJ, den Uijl DW, Abraham TP, Calkins H, Bax JJ
Over the past few years, integration of different imaging modalities to guide catheter ablation procedures for atrial fibrillation has become possible. Various strategies are nowadays available that allow integration of the anatomical information provided by fluoroscopy, computed tomography, magnetic resonance imaging, or intracardiac echocardiography with the information provided by electroanatomic mapping. This review discusses the different image integration techniques, and an overview of the... Abstract
Cited 9 times since 2008 (0.6 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 10 Suppl 3, 1 1 2008, Pages iii73-9 Predicting response to CRT. The value of two- and three-dimensional echocardiography. Marsan NA, Breithardt OA, Delgado V, Bertini M, Tops LF
Recently, it has been suggested that a direct assessment of left ventricular (LV) mechanical dyssynchrony may improve the selection of candidates to cardiac resynchronization therapy (CRT). In fact, when the established clinical and electrocardiographic selection criteria are applied, response to CRT may vary widely and up to one-third of the patients fail to benefit from CRT. Echocardiography has been extensively applied to assess LV dyssynchrony and to predict favourable response to CRT, using... Abstract
Cited 84 times since 2008 (5.4 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 21, Issue 11, 1 1 2008, Pages 1244-1250 Relation between global left ventricular longitudinal strain assessed with novel automated function imaging and biplane left ventricular ejection fraction in patients with coronary artery disease. Delgado V, Mollema SA, Ypenburg C, Tops LF, van der Wall EE, Schalij MJ, Bax JJ
Objective: Automated function imaging (AFI) is a novel algorithm based on speckle-tracking imaging that can be used for assessment of global longitudinal strain of the left ventricle. The purpose of this study was to evaluate the relation between global longitudinal peak systolic strain average (GLPSS Avg) assessed by AFI and left ventricular ejection fraction (LVEF). Methods: The study population consisted of 222 consecutive patients with coronary artery disease (99 patients with acute ST-segme... Abstract
Cited 29 times since 2008 (1.8 per year) source: EuropePMC
The American journal of cardiology, Volume 102, Issue 10, 6 1 2008, Pages 1366-1372 Comparison between tissue Doppler imaging and velocity-encoded magnetic resonance imaging for measurement of myocardial velocities, assessment of left ventricular dyssynchrony, and estimation of left ventricular filling pressures in patients with ischemic cardiomyopathy. Marsan NA, Westenberg JJ, Tops LF, Ypenburg C, Holman ER, Reiber JH, de Roos A, van der Wall EE, Schalij MJ, Roelandt JR, Bax JJ
Velocity-encoded magnetic resonance imaging (VE-MRI), commonly used to perform flow measurements, can be applied for myocardial velocity analysis, similar to tissue Doppler imaging (TDI). In this study, a comparison between VE-MRI and TDI was performed for the assessment of left ventricular dyssynchrony and left ventricular filling pressures. Ten healthy volunteers and 22 patients with heart failure secondary to ischemic cardiomyopathy underwent both VE-MRI and TDI. Longitudinal myocardial peak... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 94, Issue 8, 1 1 2008, Pages 973-975 Multislice CT: is it essential before atrial fibrillation ablation? Tops LF, Schalij MJ
Cited 11 times since 2008 (0.7 per year) source: EuropePMC
Current problems in cardiology, Volume 33, Issue 8, 1 1 2008, Pages 417-457 Percutaneous valve procedures: an update. Tops LF, Kapadia SR, Tuzcu EM, Vahanian A, Alfieri O, Webb JG, Bax JJ
Valvular heart disease is an important cause of morbidity and mortality. Aortic stenosis and mitral regurgitation account for the majority of patients with native valve disease. Although surgical treatment provides satisfactory outcome, a large proportion of patients do not undergo a surgical intervention, because of the high estimated operative risk and multiple comorbidities. Recently, new techniques that enable percutaneous treatment of valvular heart disease have been developed and their fea... Abstract
Cited 27 times since 2008 (1.7 per year) source: EuropePMC
Heart rhythm, Volume 5, Issue 10, 24 4 2008, Pages 1403-1410 Real-time integration of intracardiac echocardiography and multislice computed tomography to guide radiofrequency catheter ablation for atrial fibrillation. den Uijl DW, Tops LF, Tolosana JM, Schuijf JD, Trines SA, Zeppenfeld K, Bax JJ, Schalij MJ
Background: Multislice computed tomography (MSCT) integration is commonly used to guide radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). MSCT provides detailed anatomical information but lacks the ability to provide real-time anatomy during RFCA. Intracardiac echocardiography (ICE) allows real-time visualization of cardiac structures. Objective: The purpose of this study was to investigate the feasibility of three-dimensional (3D) anatomical mapping of the left atrium (LA) w... Abstract
Cited 73 times since 2008 (4.6 per year) source: EuropePMC
The American journal of cardiology, Volume 102, Issue 7, 18 3 2008, Pages 847-853 Comparison of left atrial volumes and function by real-time three-dimensional echocardiography in patients having catheter ablation for atrial fibrillation with persistence of sinus rhythm versus recurrent atrial fibrillation three months later. Marsan NA, Tops LF, Holman ER, Van de Veire NR, Zeppenfeld K, Boersma E, van der Wall EE, Schalij MJ, Bax JJ
Real-time 3-dimensional echocardiography (RT3DE) can provide a unique combination of accurate left atrial (LA) volume quantification and rapid, automatic assessment of LA function. The aim of the study was to evaluate the changes in LA volumes and function in patients with atrial fibrillation (AF) undergoing radiofrequency catheter ablation (RFCA) using RT3DE; 57 consecutive patients referred for RFCA were studied. Paroxysmal AF was present in 43 patients (75%) and persistent AF in 14 (25%). Aft... Abstract
Cited 247 times since 2008 (15.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 51, Issue 20, 1 1 2008, Pages 1944-1952 Assessment of left ventricular dyssynchrony by speckle tracking strain imaging comparison between longitudinal, circumferential, and radial strain in cardiac resynchronization therapy. Delgado V, Ypenburg C, van Bommel RJ, Tops LF, Mollema SA, Marsan NA, Bleeker GB, Schalij MJ, Bax JJ
Objectives: The objective of this study was to assess the usefulness of each type of strain for left ventricular (LV) dyssynchrony assessment and its predictive value for a positive response after cardiac resynchronization therapy (CRT). Furthermore, changes in extent of LV dyssynchrony for each type of strain were evaluated during follow-up. Background: Different echocardiographic techniques have been proposed for assessment of LV dyssynchrony. The novel 2-dimensional (2D) speckle tracking stra... Abstract
Cited 247 times since 2008 (15.4 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 1, Issue 3, 1 1 2008, Pages 321-330 Noninvasive evaluation of the aortic root with multislice computed tomography implications for transcatheter aortic valve replacement. Tops LF, Wood DA, Delgado V, Schuijf JD, Mayo JR, Pasupati S, Lamers FP, van der Wall EE, Schalij MJ, Webb JG, Bax JJ
Objectives: In the present study, the anatomy of the aortic root was assessed noninvasively with multislice computed tomography (MSCT). Background: Transcatheter aortic valve replacement has been proposed as an alternative to surgery in high-risk patients with severe aortic stenosis. For this procedure, detailed knowledge of aortic annulus diameters and the relation between the annulus and the coronary arteries is needed. Methods: In 169 patients (111 men, age 54 +/- 11 years), a 64-slice MSCT s... Abstract
Cited 73 times since 2008 (4.5 per year) source: EuropePMC
European heart journal, Volume 29, Issue 6, 27 4 2008, Pages 757-765 Mechanism of improvement in mitral regurgitation after cardiac resynchronization therapy. Ypenburg C, Lancellotti P, Tops LF, Boersma E, Bleeker GB, Holman ER, Thomas JD, Schalij MJ, Piérard LA, Bax JJ
Aims: The aim of the current study was to evaluate the relationship between the presence of left ventricular (LV) dyssynchrony at baseline and acute vs. late improvement in mitral regurgitation (MR) after cardiac resynchronization therapy (CRT). Methods and results: Sixty eight patients consecutive (LV ejection fraction 23 +/- 8%) with at least moderate MR (>or=grade 2+) were included. Echocardiography was performed at baseline, 1 day after CRT initiation and at 6 months follow-up. Speckle tr... Abstract
Cited 19 times since 2008 (1.2 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 1, Issue 1, 1 1 2008, Pages 94-106 Noncoronary applications of cardiac multidetector row computed tomography. Tops LF, Krishnàn SC, Schuijf JD, Schalij MJ, Bax JJ
Multidetector row computed tomography (MDCT) has a high diagnostic accuracy to evaluate coronary artery stenoses. Additionally, the 4-dimensional aspect of cardiac MDCT allows a comprehensive evaluation of cardiac structure and function. Left ventricular volumes and systolic function can be accurately assessed with MDCT, and imaging of myocardial infarction is a promising application of cardiac MDCT. In addition, MDCT may provide anatomical visualization of heart valves. Also, evaluation of anat... Abstract