Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
253 results
Cited 23 times since 2014 (2.2 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 148, Issue 4, 15 3 2014, Pages 1490-1497 Exercise capacity in children after total cavopulmonary connection: lateral tunnel versus extracardiac conduit technique. Bossers SS, Helbing WA, Duppen N, Kuipers IM, Schokking M, Hazekamp MG, Bogers AJ, Ten Harkel AD, Takken T
Objectives: In patients with univentricular heart disease, the total cavopulmonary connection (TCPC) is the preferred treatment. TCPC can be performed using the intra-atrial lateral tunnel (ILT) or extracardiac conduit (ECC) technique. The purpose of the present study was to evaluate exercise capacity in contemporary TCPC patients and compare the results between the 2 techniques. Methods: A total of 101 TCPC patients (ILT, n=42; ECC, n=59; age, 12.2±2.6 years; age at TCPC completion, 3.2±1.1 yea... Abstract
Cited 18 times since 2013 (1.7 per year) source: EuropePMC
International journal of cardiology, Volume 169, Issue 6, 11 2 2013, Pages 439-444 5-year serial follow-up of clinical condition and ventricular function in patients after repair of tetralogy of Fallot. Luijnenburg SE, Helbing WA, Moelker A, Kroft LJ, Groenink M, Roos-Hesselink JW, de Rijke YB, Hazekamp MG, Bogers AJ, Vliegen HW, Mulder BJ
Objective: To study the changes over time in biventricular size and function, and clinical parameters in patients after repair of tetralogy of Fallot (TOF) without subsequent pulmonary valve replacement (PVR). Methods: We prospectively included 78 non-PVR patients (age 20(6-60)years at baseline), who were studied twice with a 5-year interval. Patients underwent magnetic resonance imaging for assessment of biventricular size and function. Exercise testing and electrocardiography were performed to... Abstract
Cited 17 times since 2013 (1.6 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 147, Issue 5, 12 2 2013, Pages 1561-1567 Left and right ventricular performance after arterial switch operation. Klitsie LM, Roest AA, Kuipers IM, Hazekamp MG, Blom NA, Ten Harkel AD
Objective: Recent descriptions of decreased exercise capacity 10 to 15 years after arterial switch operation (ASO) suggest subclinical hemodynamic restrictions. Persistent impairment of ventricular performance following ASO may add to this. We aimed to characterize the time course of changes in biventricular performance within the first year following ASO. Methods: We prospectively included 26 patients with transposition of the great arteries undergoing ASO and 20 age-matched controls. Left and... Abstract
Cited 17 times since 2013 (1.6 per year) source: EuropePMC
International journal of cardiology, Volume 169, Issue 2, 8 2 2013, Pages 139-144 Postoperative arrhythmias in adults with congenital heart disease: incidence and risk factors. Koyak Z, Achterbergh RC, de Groot JR, Berger F, Koolbergen DR, Bouma BJ, Lagrand WK, Hazekamp MG, Blom NA, Mulder BJ
Background: Little is known about the clinical impact of arrhythmias after surgery for congenital heart disease (CHD) in adults. Therefore, we investigated the prevalence of in-hospital arrhythmias after CHD surgery and their impact on clinical outcome. Methods: This was a multicenter retrospective study and included adults who underwent congenital cardiac surgery between January 2009 and December 2011. Clinical events were defined as all cause mortality, heart failure (HF) requiring medical tre... Abstract
Cited 48 times since 2013 (4.5 per year) source: EuropePMC
Intensive care medicine, Volume 39, Issue 11, 31 5 2013, Pages 2011-2019 Safety and effects of two red blood cell transfusion strategies in pediatric cardiac surgery patients: a randomized controlled trial. de Gast-Bakker DH, de Wilde RB, Hazekamp MG, Sojak V, Zwaginga JJ, Wolterbeek R, de Jonge E, Gesink-van der Veer BJ
Objective: To investigate the safety and effects of a restrictive red blood cell (RBC) transfusion strategy in pediatric cardiac surgery patients. Design: Randomized controlled trial. Setting: Pediatric ICU in an academic tertiary care center, Leiden University Medical Center, Leiden, The Netherlands. Patients: One hundred seven patients with non-cyanotic congenital heart defects between 6 weeks and 6 years of age. One hundred three patients underwent corrective surgery on cardiopulmonary bypass... Abstract
Cited 9 times since 2013 (0.8 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 96, Issue 4, 16 3 2013, Pages 1390-1397 Variation in coronary anatomy in adult patients late after arterial switch operation: a computed tomography coronary angiography study. Veltman CE, Beeres SLMA, Kalkman DN, Kelder TP, Kiès P, Vliegen HW, Hazekamp MG, Delgado V, Kroft LJM, van der Wall EE, Gittenberger-de Groot AC, Scholte AJHA, Schalij MJ, Jongbloed MRM
Background: The arterial switch operation is the current treatment for transposition of the great arteries. Long-term outcome mainly depends on the patency of the transferred coronary arteries. This study assessed the presence of abnormal coronary findings and neoaortic root dilation late after arterial switch operation. Methods: In 30 adult patients after arterial switch operation (22 men, 22 ± 3 years), computed tomography angiography was performed to assess the coronary anatomy and abnormal c... Abstract
Cited 9 times since 2013 (0.8 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 96, Issue 2, 24 4 2013, Pages 629-636 Enhanced characterization of ventricular performance after coarctation repair in neonates and young children. Klitsie LM, Roest AA, Kuipers IM, Van der Hulst AE, Hazekamp MG, Blom NA, Ten Harkel AD
Background: Within the group of patients undergoing coarctectomy today, two subgroups can be identified: neonates with a critical coarctation and nonneonatal patients. We hypothesize that patients who have to undergo repair in the neonatal period will have more persistent impairment of ventricular performance postoperatively. Accordingly, we aimed to characterize biventricular performance after coarctectomy in neonatal and nonneonatal patients. Methods: Children (aged 0 to 17 years) undergoing a... Abstract
Cited 15 times since 2013 (1.4 per year) source: EuropePMC
Journal of cardiothoracic and vascular anesthesia, Volume 27, Issue 4, 28 4 2013, Pages 723-727 Determinants of clinical right ventricular failure after congenital heart surgery in adults. Schuuring MJ, van Gulik EC, Koolbergen DR, Hazekamp MG, Lagrand WK, Backx AP, Mulder BJ, Bouma BJ
Objectives: Right ventricular (RV) failure after cardiac surgery is a clinical entity with high morbidity and mortality. Patients with congenital heart disease (CHD) often undergo right-sided cardiac surgery. The authors aimed to identify determinants of RV failure after cardiac surgery to differentiate patients with increased risk. Design: A retrospective chart review. Setting: University hospital. Participants: Adults with CHD operated on between January 2001 and January 2011. Interventions: C... Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 44, Issue 4, 26 4 2013, Pages 654-655 Very early repair of tetralogy of Fallot: we can, but should we? Hazekamp MG
Cited 21 times since 2013 (1.9 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 44, Issue 2, 13 2 2013, Pages 269-274 Disparity in right vs left ventricular recovery during follow-up after ventricular septal defect correction in children. Klitsie LM, Kuipers IM, Roest AA, Van der Hulst AE, Stijnen T, Hazekamp MG, Blom NA, Ten Harkel AD
Objectives: Long-term prognosis after ventricular septal defect (VSD) correction in childhood is excellent. Nevertheless, decreased biventricular systolic performance has been described immediately following VSD surgery in children. In an effort to better understand this decrease and its time-course, we characterized biventricular systolic performance following VSD closure in paediatric patients up to 20 months postoperatively. Methods: Thirty-nine children undergoing VSD surgery and 22 age-matc... Abstract
Case reports in pediatrics, Volume 2013, 28 4 2013, Pages 426923 Volumetric Computed Tomography Angiography in the Evaluation of Mediastinal Fluid Collections following Congenital Cardiac Surgery. Roest AA, Roelofs J, Hazekamp MG, Rijlaarsdam ME, Geleijns J, Kroft LJ
We present 3 patients with 4 causes of mediastinal fluid collection after congenital cardiac surgery in this extended case report. Volumetric computed tomography played an essential role in diagnosing causes and extent, relevant to subsequent management. Recent advances in volumetric computed tomography allow fast and accurate imaging of cardiovascular and extravascular structures in children with acceptable radiation dose, providing a powerful imaging tool for the evaluation of complications af... Abstract
Cited 4 times since 2012 (0.4 per year) source: EuropePMC
Case reports in pediatrics, Volume 2012, 12 2 2012, Pages 314256 Left pulmonary artery thrombosis in a neonate with left lung hypoplasia. van Schendel MP, Visser DH, Rammeloo LA, Hazekamp MG, Hruda J
Thrombotic events in neonates may origin from fetal life. A 4-day-old newborn infant with a family history of heterozygous type 1 protein C deficiency was diagnosed with left lung hypoplasia and left pulmonary artery thrombosis. Its source was prenatally closed ductus arteriosus. Surgical removal of the thrombus was performed. Abstract
Cited 13 times since 2012 (1.1 per year) source: EuropePMC
Expert review of cardiovascular therapy, Volume 10, Issue 12, 1 1 2012, Pages 1517-1531 Surgical versus percutaneous treatment of aortic coarctation: new standards in an era of transcatheter repair. Luijendijk P, Bouma BJ, Groenink M, Boekholdt M, Hazekamp MG, Blom NA, Koolbergen DR, de Winter RJ, Mulder BJ
Aortic coarctation is a common congenital cardiovascular defect, which can be diagnosed over a wide range of ages and with varying degrees of severity. Surgery has proven to be an effective treatment for the management of native aortic coarctation, and remains the treatment of choice in neonates. Balloon angioplasty with or without stenting has evolved rapidly over the past decade. Balloon angioplasty is the treatment of choice in children with re-coarctation, and currently available immediate r... Abstract
Cited 3 times since 2012 (0.3 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 20, Issue 12, 1 1 2012, Pages 509-512 Two cases of aorto-right atrial tunnel: clinical presentation, imaging and percutaneous closure. de Winter RJ, Blom NA, Straver B, Bouma BJ, Backx AP, Clur SA, Kuipers IM, Hoekstra F, Boekholdt SM, Groenink M, Koolbergen DR, Hazekamp MG, Mulder BJ
Communication between the aortic sinus and a cardiac chamber is a rare anomaly that can be diagnosed in children and young adults. We describe two cases with a tunnel between the aortic sinus and right atrium, discuss diagnostic modalities, and review the literature on this anomaly. Abstract
Cited 1 times since 2012 (0.1 per year) source: EuropePMC
Cardiology in the young, Volume 23, Issue 4, 2 1 2012, Pages 540-545 Peri-operative care in adults with congenital heart disease: room for improvement in after care. Schoormans D, Smets EM, Zwart R, Sprangers MA, Veelenturg TH, de Mol BA, Hazekamp MG, Koolbergen DR, Sojak V, Bouma BJ, Groenink M, Boekholdt MS, Backx AP, Mulder BJ
Background: Patient satisfaction with care has received little attention within the field of congenital heart disease. Our objective was to examine patient satisfaction with the care received when undergoing open-heart surgery in order to identify the best and worst aspects of peri-operative care. Moreover, we examined whether having contact with a specialised nurse in addition to usual care is associated with higher patient satisfaction levels. Methods: Patient satisfaction was measured by the... Abstract
Cited 17 times since 2012 (1.5 per year) source: EuropePMC
Pediatric cardiology, Volume 34, Issue 3, 22 4 2012, Pages 630-638 Tissue Doppler imaging detects impaired biventricular performance shortly after congenital heart defect surgery. Klitsie LM, Hazekamp MG, Roest AA, Van der Hulst AE, Gesink-van der Veer BJ, Kuipers IM, Blom NA, Ten Harkel AD
Cardiac surgery with cardiopulmonary bypass is associated with the development of a systemic inflammatory response, which can lead to myocardial damage. However, knowledge concerning the time course of ventricular performance deterioration and restoration after correction of a congenital heart defect (CHD) in pediatric patients is sparse. Therefore, the authors perioperatively quantified left ventricular (LV) and right ventricular (RV) performance using echocardiography. Their study included 141... Abstract
Cited 19 times since 2012 (1.6 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 94, Issue 6, 13 2 2012, Pages 2077-2082 Mild residual pulmonary stenosis in tetralogy of fallot reduces risk of pulmonary valve replacement. van der Hulst AE, Hylkema MG, Vliegen HW, Delgado V, Hazekamp MG, Rijlaarsdam ME, Holman ER, Blom NA, Roest AA
Background: Current surgical strategies that aim at preventing pulmonary regurgitation in patients with corrected tetralogy of Fallot (cToF) may result in a certain grade of residual pulmonary stenosis (PS). The clinical implications of a postoperative residual PS in cToF patients remain unclear. Pulmonary valve replacement (PVR) is frequently needed during follow-up of cToF patients. The aim of the current study was to determine the role of residual PS in the need for PVR during follow-up in cT... Abstract
Cited 11 times since 2012 (0.9 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 15, Issue 4, 3 1 2012, Pages 685-689 Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery. Verweij EJ, Hogenbirk K, Roest AA, van Brempt R, Hazekamp MG, de Jonge E
Objectives: Low cardiac output syndrome is common after paediatric cardiac surgery. Previous studies suggested that hydrocortisone administration may improve haemodynamic stability in case of resistant low cardiac output syndrome in critically ill children. This study was set up to test the hypothesis that the effects of hydrocortisone on haemodynamics in children with low cardiac output syndrome depend on the presence of (relative) adrenal insufficiency. Methods: A retrospective study was done... Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 42, Issue 1, 10 2 2012, Pages 31-32 Reoperations after paediatric Ross operation. Hazekamp MG
Cited 9 times since 2012 (0.7 per year) source: EuropePMC
The American journal of cardiology, Volume 109, Issue 12, 22 4 2012, Pages 1792-1796 Relation of prolonged tissue Doppler imaging-derived atrial conduction time to atrial arrhythmia in adult patients with congenital heart disease. van der Hulst AE, Roest AA, Holman ER, Vliegen HW, Hazekamp MG, Bax JJ, Blom NA, Delgado V
Atrial arrhythmia (AA) is common in adult patients with congenital heart disease (CHD). To enable the prevention of AA or its complications, timely identification of adult patients with CHD at risk of AA is crucial. Long total atrial activation times have been related to AA. Tissue Doppler imaging (TDI) permits noninvasive evaluation of the total atrial conduction time (PA-TDI duration). The present study evaluated the association between the PA-TDI duration and the development of AA in adult pa... Abstract