Cited 5 times since 2007 (0.3 per year) source: EuropePMC Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Volume 9, Issue 3, 1 1 2007, Pages 557-563 Validation of a high-resolution, phase contrast cardiovascular magnetic resonance sequence for evaluation of flow in coronary artery bypass grafts. Salm LP, Schuijf JD, Lamb HJ, Bax JJ, Vliegen HW, Jukema JW, van der Wall EE, de Roos A, Doornbos J
The aim was to validate a magnetic resonance high-resolution, phase-contrast sequence for quantifying flow in small and large vessels and to demonstrate its feasibility to measure flow in coronary artery bypass grafts. A breathhold, echo planar imaging (EPI) sequence was developed and validated in a flow phantom using a fast field echo (FFE) sequence as reference. In 17 volunteers aortic flow was measured using both sequences. In 5 patients flow in the left internal mammary artery (LIMA) and aorta was measured at rest and during adenosine stress, and coronary flow reserve (CFR) was calculated; in 7 patients, vein graft flow velocity was measured. In the flow phantom measurements, the EPI sequence yielded an excellent correlation with the FFE sequence (r = 0.99; p < 0.001 for all parameters). In healthy volunteers, aortic volume flow correlated well (r = 0.88; p < 0.01), with a minor overestimation. It was feasible to measure flow velocity in the LIMA and vein grafts of the 12 patients. The high-resolution, breathhold cardiovascular magnetic resonance velocity-encoded sequence correlated well with a free-breathing, FFE sequence in a flow phantom and in the aortae of healthy volunteers. Using the EPI sequence, it is feasible to measure flow velocity in both LIMA and vein grafts, and in the aorta.
