Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
53 results
Cited 8 times since 2015 (0.9 per year) source: EuropePMC
Autonomic neuroscience : basic & clinical, Volume 189, 14 2 2015, Pages 60-67 New insights in the neuroanatomy of the human adult superior hypogastric plexus and hypogastric nerves. Kraima AC, van Schaik J, Susan S, van de Velde CJ, Hamming JF, Lakke EA, DeRuiter MC
Background: The superior hypogastric plexus (SHP) is an autonomic plexus, located ventrally to the abdominal aorta and its bifurcation, innervating pelvic viscera. It is classically described as being composed of merely sympathetic fibres. However, post-operative complications after surgery damaging the peri-aortic retroperitoneal compartment suggest the existence of parasympathetic fibres. This immunohistochemical study describes the neuroanatomical composition of the human mature SHP. Material... Abstract
Cited 35 times since 2014 (3.7 per year) source: EuropePMC
Preventive veterinary medicine, Volume 118, Issue 1, 23 4 2014, Pages 80-92 Housing and management factors associated with indicators of dairy cattle welfare. de Vries M, Bokkers EA, van Reenen CG, Engel B, van Schaik G, Dijkstra T, de Boer IJ
Knowledge of potential synergies and trade-offs between housing and management factors for different aspects of animal welfare is essential for farmers who aim to improve the level of welfare in their herds. The aim of this research was to identify and compare housing and management factors associated with prevalence of lameness, prevalence of lesions or swellings, prevalence of dirty hindquarters, and frequency of displacements (social behavior) in dairy herds in free-stall housing. Seven obser... Abstract
Cited 829 times since 2014 (85.4 per year) source: EuropePMC
Science (New York, N.Y.), Volume 345, Issue 6204, 1 1 2014, Pages 1251086 Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Saeed S, Quintin J, Kerstens HH, Rao NA, Aghajanirefah A, Matarese F, Cheng SC, Ratter J, Berentsen K, van der Ent MA, Sharifi N, Janssen-Megens EM, Ter Huurne M, Mandoli A, van Schaik T, Ng A, Burden F, Downes K, Frontini M, Kumar V, Giamarellos-Bourboulis EJ, Ouwehand WH, van der Meer JW, Joosten LA, Wijmenga C, Martens JH, Xavier RJ, Logie C, Netea MG, Stunnenberg HG
Monocyte differentiation into macrophages represents a cornerstone process for host defense. Concomitantly, immunological imprinting of either tolerance or trained immunity determines the functional fate of macrophages and susceptibility to secondary infections. We characterized the transcriptomes and epigenomes in four primary cell types: monocytes and in vitro-differentiated naïve, tolerized, and trained macrophages. Inflammatory and metabolic pathways were modulated in macrophages, including... Abstract
Cited 26 times since 2013 (2.5 per year) source: EuropePMC
Journal of dairy science, Volume 97, Issue 2, 2 1 2013, Pages 715-730 Exploring the value of routinely collected herd data for estimating dairy cattle welfare. de Vries M, Bokkers EA, van Schaik G, Engel B, Dijkstra T, de Boer IJ
Routine on-farm assessment of dairy cattle welfare is time consuming and, therefore, expensive. A promising strategy to assess dairy cattle welfare more efficiently is to estimate the level of animal welfare based on herd data available in national databases. Our aim was to explore the value of routine herd data (RHD) for estimating dairy cattle welfare at the herd level. From November 2009 through March 2010, 7 trained observers collected data for 41 welfare indicators in a selected sample of 1... Abstract
Cited 40 times since 2013 (3.7 per year) source: EuropePMC
Journal of dairy science, Volume 96, Issue 10, 9 2 2013, Pages 6264-6273 Evaluating results of the Welfare Quality multi-criteria evaluation model for classification of dairy cattle welfare at the herd level. de Vries M, Bokkers EA, van Schaik G, Botreau R, Engel B, Dijkstra T, de Boer IJ
The Welfare Quality multi-criteria evaluation (WQ-ME) model aggregates scores of single welfare measures into an overall assessment for the level of animal welfare in dairy herds. It assigns herds to 4 welfare classes: unacceptable, acceptable, enhanced, or excellent. The aim of this study was to demonstrate the relative importance of single welfare measures for WQ-ME classification of a selected sample of Dutch dairy herds. Seven trained observers quantified 63 welfare measures of the Welfare Q... Abstract
Cited 28 times since 2012 (2.4 per year) source: EuropePMC
Viruses, Volume 4, Issue 8, 22 4 2012, Pages 1328-1334 Performance of VIDISCA-454 in feces-suspensions and serum. De Vries M, Oude Munnink BB, Deijs M, Canuti M, Koekkoek SM, Molenkamp R, Bakker M, Jurriaans S, Van Schaik BDC, Luyf AC, Olabarriaga SD, Van Kampen AHC, Van der Hoek L
Virus discovery combining sequence unbiased amplification with next generation sequencing is now state-of-the-art. We have previously determined that the performance of the unbiased amplification technique which is operational at our institute, VIDISCA-454, is efficient when respiratory samples are used as input. The performance of the assay is, however, not known for other clinical materials like blood or stool samples. Here, we investigated the sensitivity of VIDISCA-454 with feces-suspensions... Abstract
Cited 37 times since 2011 (2.9 per year) source: EuropePMC
Journal of dairy science, Volume 94, Issue 7, 1 1 2011, Pages 3213-3228 Invited review: associations between variables of routine herd data and dairy cattle welfare indicators. de Vries M, Bokkers EA, Dijkstra T, van Schaik G, de Boer IJ
As farm animal welfare is high on the political and societal agendas of many countries, considerable pressure exists to establish audit programs in which farm animal welfare is routinely monitored. On-farm assessment of animal welfare, however, is time-consuming and costly. A promising strategy to monitor animal welfare more efficiently is to first estimate the level of animal welfare on a farm based on routine herd data that are available in national databases. It is not currently known which v... Abstract
Cited 52 times since 2011 (3.9 per year) source: EuropePMC
PloS one, Volume 6, Issue 1, 24 4 2011, Pages e16118 A sensitive assay for virus discovery in respiratory clinical samples. de Vries M, Deijs M, Canuti M, van Schaik BD, Faria NR, van de Garde MD, Jachimowski LC, Jebbink MF, Jakobs M, Luyf AC, Coenjaerts FE, Claas EC, Molenkamp R, Koekkoek SM, Lammens C, Leus F, Goossens H, Ieven M, Baas F, van der Hoek L
In 5-40% of respiratory infections in children, the diagnostics remain negative, suggesting that the patients might be infected with a yet unknown pathogen. Virus discovery cDNA-AFLP (VIDISCA) is a virus discovery method based on recognition of restriction enzyme cleavage sites, ligation of adaptors and subsequent amplification by PCR. However, direct discovery of unknown pathogens in nasopharyngeal swabs is difficult due to the high concentration of ribosomal RNA (rRNA) that acts as competitor.... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
BMC bioinformatics, Volume 11, 14 2 2010, Pages 598 Initial steps towards a production platform for DNA sequence analysis on the grid. Luyf AC, van Schaik BD, de Vries M, Baas F, van Kampen AH, Olabarriaga SD
Background: Bioinformatics is confronted with a new data explosion due to the availability of high throughput DNA sequencers. Data storage and analysis becomes a problem on local servers, and therefore it is needed to switch to other IT infrastructures. Grid and workflow technology can help to handle the data more efficiently, as well as facilitate collaborations. However, interfaces to grids are often unfriendly to novice users. Results: In this study we reused a platform that was developed in... Abstract
Cited 7 times since 2010 (0.5 per year) source: EuropePMC
The Journal of surgical research, Volume 164, Issue 1, 2 1 2010, Pages e91-7 Impact of complications after surgery for colorectal liver metastasis on patient survival. Schepers A, Mieog S, van de Burg BB, van Schaik J, Liefers GJ, Marang-van de Mheen PJ
Background: In some patients with colorectal liver metastases it is not clear whether liver resection or isolated liver perfusion is the best treatment option. For instance, the risk of complications after surgery may be so substantial and affect subsequent survival. Aim of the present study is to compare complication occurrence and its effect on survival after liver resection and perfusion. Methods: Patient records of all 225 patients with colorectal liver metastases treated with liver resectio... Abstract
Cited 122 times since 2008 (7.8 per year) source: EuropePMC
Annals of neurology, Volume 64, Issue 5, 1 1 2008, Pages 514-522 Randomized, controlled trial of miglustat in Gaucher's disease type 3. Schiffmann R, Fitzgibbon EJ, Harris C, DeVile C, Davies EH, Abel L, van Schaik IN, Benko W, Timmons M, Ries M, Vellodi A
Objective: To evaluate the efficacy and safety of miglustat, concomitant with enzyme replacement therapy (ERT), in patients with Gaucher's disease type 3 (GD3). Methods: This 24-month, phase II, open-label clinical trial of miglustat in GD3 was conducted in two phases. During the initial 12 months, patients were randomized 2:1 to receive miglustat or "no miglustat treatment." The randomized phase was followed by an optional 12-month extension phase in which all patients received m... Abstract
Journal of human nutrition, Volume 30, Issue 6, 1 1 1976, Pages 377-380 The role of carbohydrates, and of sugar in particular, in our diet. van Schaik TF, Ing
Voeding, Volume 24, 1 1 1963, Pages 162-170 [Changes in food habits as a problem for many nations]. van SCHAIK