Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
194 results
Cited 1 times since 2006 (0.1 per year) source: EuropePMC
Thorax, Volume 61, Issue 12, 1 1 2006, Pages 1034 Alpha-1-antitrypsin augmentation treatment: does one size fit all? Stolk J
Cited 41 times since 2006 (2.3 per year) source: EuropePMC
Thorax, Volume 62, Issue 3, 7 1 2006, Pages 242-247 A disintegrin and metalloprotease 33 and chronic obstructive pulmonary disease pathophysiology. Gosman MM, Boezen HM, van Diemen CC, Snoeck-Stroband JB, Lapperre TS, Hiemstra PS, Ten Hacken NH, Stolk J, Postma DS
Background: Chronic obstructive pulmonary disease (COPD) is a respiratory disorder with increasing prevalence and mortality. It is associated with airway obstruction, increased airway hyper-responsiveness (AHR), and ongoing airway and lung inflammation dominated by CD8 lymphocytes and neutrophils. Single-nucleotide polymorphisms (SNPs) in a disintegrin and metalloprotease 33 (ADAM33) gene have been associated with AHR and COPD. Objective: To assess whether SNPs in ADAM33 are associated with the... Abstract
Cited 19 times since 2006 (1.1 per year) source: EuropePMC
Disability and rehabilitation, Volume 28, Issue 20, 1 1 2006, Pages 1251-1258 Self-worth, perceived competence, and behaviour problems in children with cerebral palsy. Schuengel C, Voorman J, Stolk J, Dallmeijer A, Vermeer A, Becher J
Purpose: To examine the relevance of physical disabilities for self-worth and perceived competence in children with cerebral palsy (CP), and to examine associations between behaviour problems and self-worth and perceived competence. Methods: The Harter scales for self-worth and perceived competence and a new scale for perceived motor competence were used in a sample of 80 children with CP. Their motor functioning was assessed with the Gross Motor Functioning Measure (GMFM) and behaviour problems... Abstract
Cited 22 times since 2006 (1.2 per year) source: EuropePMC
American journal of human genetics, Volume 79, Issue 1, 1 1 2006, Pages 184-6; author reply 186-7 The SERPINE2 gene and chronic obstructive pulmonary disease. Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N
Cited 2 times since 2006 (0.1 per year) source: EuropePMC
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, Volume 220, Issue 4, 1 1 2006, Pages 533-539 Finite element analysis of the long-term fixation strength of cemented ceramic cups. Janssen D, Stolk J, Verdonschot N
Clinical studies have shown that adequate fixation of ceramic cups using bone cement is difficult to achieve. As the cement-ceramic bond strength is low, a satisfactory fixation strength requires a cup design that allows mechanical interlocking, although such a design will probably promote cement cracking and therefore cup loosening in the long term. An investigation has been carried out to establish whether a cemented ceramic cup can be designed in such a way that both a satisfactory initial fi... Abstract
Cited 6 times since 2006 (0.3 per year) source: EuropePMC
The European respiratory journal, Volume 28, Issue 2, 29 5 2006, Pages 323-329 Ventilation inhomogeneity in alpha1-antitrypsin-deficient emphysema. Fregonese L, van Veen HP, Sterk PJ, Stolk J
The slope of phase III of the single-breath nitrogen wash-out test (sbN2-test) measures ventilation inhomogeneity and, in smokers, is strongly associated with small airways pathology. The present authors aimed to study ventilation inhomogeneity in emphysema related to type Z alpha1-antitrypsin (AAT) and to assess its relationship with indices of parenchymal damage and airways obstruction. A total of 18 subjects, consisting of ex-smokers with type Z AAT and emphysema (confirmed by computed tomogr... Abstract
Cited 85 times since 2006 (4.7 per year) source: EuropePMC
Thorax, Volume 61, Issue 6, 14 2 2006, Pages 485-490 Validation of computed tomographic lung densitometry for monitoring emphysema in alpha1-antitrypsin deficiency. Parr DG, Stoel BC, Stolk J, Stockley RA
Background: Lung densitometry derived from computed tomographic images offers an opportunity to quantify emphysema non-invasively, but a pathological standard cannot be applied to validate its use in longitudinal monitoring studies. Consequently, forced expiratory volume in 1 second (FEV1) remains the standard against which new methods must be judged. We related progression of densitometry (15th percentile point and voxel index, threshold -950 Hounsfield units) to disease stage and FEV1 decline... Abstract
Cited 71 times since 2006 (3.9 per year) source: EuropePMC
American journal of clinical pathology, Volume 125, Issue 2, 1 1 2006, Pages 184-192 Expression of epidermal growth factors and their receptors in the bronchial epithelium of subjects with chronic obstructive pulmonary disease. de Boer WI, Hau CM, van Schadewijk A, Stolk J, van Krieken JH, Hiemstra PS
Smoking may affect epithelial repair and differentiation differentially in smokers with and without chronic obstructive pulmonary disease (COPD). We hypothesized that epithelial repair is disturbed in patients with COPD owing to higher expression of epidermal growth factor (EGF)-like factors and/or receptors. We studied epithelial expression of EGF, transforming growth factor a, amphiregulin, heregulin (HRG), betacellulin (BTC), and their receptors, EGFR, HER-2, and HER-3, by immunohistochemical... Abstract
Cited 41 times since 2006 (2.2 per year) source: EuropePMC
Human mutation, Volume 27, Issue 1, 1 1 2006, Pages 103-109 Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease. Chappell S, Daly L, Morgan K, Guetta Baranes T, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra P, Miniati M, Monti S, O'Connor CM, Kalsheker N
Chronic obstructive pulmonary disease (COPD) is a major cause of mortality and morbidity worldwide. While cigarette smoking is a major cause of COPD, only 15% of smokers develop the disease, indicating major genetic influences. The most widely recognized candidate gene in COPD is SERPINA1, although it has been suggested that SERPINA3 may also play a role. To detect cryptic genetic variants that might contribute to disease, we identified 15 SNP haplotype tags from high-density SNP maps of the two... Abstract
Cited 2 times since 2006 (0.1 per year) source: EuropePMC
Radiology, Volume 238, Issue 1, 1 1 2006, Pages 374-5; author reply 375 Prediction of pulmonary function in COPD on the basis of CT measurements of bronchial wall thickness. Nieber M, Putter H, Stolk J, Reiber JH, Stoel BC
Cited 20 times since 2006 (1.1 per year) source: EuropePMC
International journal of chronic obstructive pulmonary disease, Volume 1, Issue 2, 1 1 2006, Pages 151-160 Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management. Stolk J, Seersholm N, Kalsheker N
The Alpha One International Registry (AIR), a multinational research program focused on alpha1-antitrypsin (AAT) deficiency, was formed in response to a World Health Organization recommendation. Each of the nearly 20 participating countries maintains a national registry of patients with AAT deficiency and contributes to an international database located in Malmö, Sweden. This database is designed to increase understanding of AAT deficiency. Additionally, AIR members are engaged in active, wide-r... Abstract
Cited 58 times since 2005 (3.1 per year) source: EuropePMC
Investigative radiology, Volume 40, Issue 12, 1 1 2005, Pages 777-783 Variability in densitometric assessment of pulmonary emphysema with computed tomography. Bakker ME, Stolk J, Putter H, Shaker SB, Parr DG, Piitulainen E, Russi EW, Dirksen A, Stockley RA, Reiber JH, Stoel BC
Objectives: The objectives of this study were to investigate whether computed tomography (CT) densitometry can be applied consistently in different centers; and to evaluate the reproducibility of densitometric quantification of emphysema by assessment of different sources of variation, ie, intersite, interscan and inter- and intraobserver variability, in comparison with intersubject variability. Materials and methods: In 5 different hospitals, 119 patients with emphysema were scanned using stand... Abstract
Cited 10 times since 2005 (0.5 per year) source: EuropePMC
The Journal of bone and joint surgery. British volume, Volume 87, Issue 11, 1 1 2005, Pages 1561-1567 Finite-element analysis of failure of the Capital Hip designs. Janssen D, Aquarius R, Stolk J, Verdonschot N
The Capital Hip implant was a Charnley-based system which included a flanged and a roundback stem, both of which were available in stainless steel and titanium. The system was withdrawn from the market because of its inferior performance. However, all four of the designs did not produce poor rates of survival. Using a simulated-based, finite-element analysis, we have analysed the Capital Hip system. Our aim was to investigate whether our simulation was able to detect differences which could acco... Abstract
Cited 1 times since 2005 (0.1 per year) source: EuropePMC
The European respiratory journal, Volume 26, Issue 4, 1 1 2005, Pages 561-562 Case detection of alpha1-antitrypsin deficiency: does it help the patient or the doctor? Stolk J
Cited 12 times since 2005 (0.6 per year) source: EuropePMC
Journal of biomedical materials research. Part B, Applied biomaterials, Volume 74, Issue 2, 1 1 2005, Pages 747-753 The contradictory effects of pores on fatigue cracking of bone cement. Janssen D, Aquarius R, Stolk J, Verdonschot N
The beneficial effect of porosity reduction on the fatigue life of bone cement has been demonstrated in numerous experimental studies. Clinically, however, it seems that the beneficial effect of porosity reduction of cement around total hip replacement components can only be found in large follow-up studies. Little is known about the actual mechanical effect of a pore on fatigue crack formation in cement mantles. We studied the effect of pores on the crack formation process in a finite element m... Abstract
Cited 8 times since 2005 (0.4 per year) source: EuropePMC
Research in developmental disabilities, Volume 27, Issue 2, 24 4 2005, Pages 203-216 Professional caretakers as attachment figures in day care centers for children with intellectual disability and behavior problems. De Schipper JC, Stolk J, Schuengel C
Do children with intellectual disabilities (ID) show attachment behavior towards their professional caretaker? Five children, varying in chronological age, developmental age and DSM-diagnosis, were observed in a day care setting. Their attachment behavior was described by means of the Attachment Q-sort. Attachment behavior varied within and between children, irrespective of their diagnosis. This data indicates that professional caretakers are potential attachment figures for children with ID. At... Abstract
Cited 35 times since 2005 (1.8 per year) source: EuropePMC
The Journal of allergy and clinical immunology, Volume 115, Issue 6, 1 1 2005, Pages 1148-1154 Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma. Fregonese L, Swan FJ, van Schadewijk A, Dolhnikoff M, Santos MA, Daha MR, Stolk J, Tschernig T, Sterk PJ, Hiemstra PS, Rabe KF, Mauad T
Background: The mechanisms leading to death from asthma are not completely understood. Recent studies suggest the involvement of the anaphylatoxins C3a and C5a, generated during complement activation, and their receptors C3aR and C5aR in the pathogenesis of asthma. Objective: The aim of our study was to investigate the expression of C3aR and C5aR in fatal asthma. Methods: We analyzed lung tissue from 14 subjects who died of asthma (fatal asthma; FA) and 14 subjects who died of nonpulmonary cause... Abstract
Cited 16 times since 2005 (0.8 per year) source: EuropePMC
Respiratory research, Volume 6, 31 5 2005, Pages 47 Short-term variability of biomarkers of proteinase activity in patients with emphysema associated with type Z alpha-1-antitrypsin deficiency. Stolk J, Veldhuisen B, Annovazzi L, Zanone C, Versteeg EM, van Kuppevelt TH, Berden JH, Nieuwenhuizen W, Iadarola P, Luisetti M
Background: The burden of proteinases from inflammatory cells in the lung of subjects with type Pi ZZ of alpha-1-antitrypsin deficiency is higher than in those without the deficiency. Cross-sectional studies have shown increased levels of biomarkers of extracellular matrix degradation in vivo. Longitudinal variability of these biomarkers is unknown but desirable for clinical studies with proteinase inhibitors. Methods: We measured three different types of biomarkers, including desmosines, elasta... Abstract
Cited 3 times since 2005 (0.2 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 149, Issue 11, 1 1 2005, Pages 598-600 [Pneumothorax as a complication of chronic necrotizing pulmonary aspergillosis]. van Klink HC, Stolk J
A 65-year-old man with chronic obstructive pulmonary disease who had frequently been treated with prednisone for recurrent exacerbations was admitted to hospital with a pneumothorax. This proved to be a complication of a chronic necrotizing pulmonary aspergillosis. Despite maximal therapy the patient died 15 months after diagnosis from total respiratory insufficiency, the end stage of the bullous emphysema. Abstract
Cited 14 times since 2005 (0.7 per year) source: EuropePMC
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Volume 23, Issue 4, 23 4 2005, Pages 691-697 Why would cement porosity reduction be clinically irrelevant, while experimental data show the contrary. Janssen D, Stolk J, Verdonschot N
Laboratory bench tests have shown that porosity reduction increases the fatigue life of bone cement specimens. Clinically, however, the effect porosity reduction is subject to debate. We hypothesized that the discrepancy between clinical and experimental findings is related to differences in the stress distribution, which is typically uniform in experimental test specimens, while stress concentrations exist in cement around hip implants. We simulated fatigue failure of cement in a finite element... Abstract