Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
1720 results
Cited 1 times since 2022 (0.7 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 12, 1 1 2022, Pages e537-e538 Pericoronary adipose tissue attenuation: diagnostic and prognostic implications. van der Bijl P, Kuneman JH, Bax JJ
The American journal of cardiology, Volume 186, 1 1 2022, Pages 228-235 Relation Between Coronary Plaque Composition Assessed by Intravascular Ultrasound Virtual Histology and Myocardial Ischemia Assessed by Quantitative Flow Ratio. Smit JM, El Mahdiui M, de Graaf MA, Montero-Cabezas JM, Reiber JHC, Jukema JW, Scholte AJ, Knuuti J, Wijns W, Narula J, Bax JJ
Coronary plaque composition may play an important role in the induction of myocardial ischemia. Our objective was to further clarify the relation between coronary plaque composition and myocardial ischemia in patients with chest pain symptoms. The study population consisted of 103 patients who presented to the outpatient clinic or emergency department with chest pain symptoms and were referred for diagnostic invasive coronary angiography. Intravascular ultrasound virtual histology was used for t... Abstract
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 36, Issue 4, 1 1 2022, Pages 402-410 Prevalence and Prognostic Implications of Moderate or Severe Mitral Regurgitation in Patients with Bicuspid Aortic Valve. Butcher SC, Prevedello F, Fortuni F, Kong WKF, Singh GK, Ng ACT, Perry R, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Gay LG, Fijałkowski M, Liang M, Tay E, Ajmone Marsan N, Selvanayagam JB, Pinto F, Zamorano JL, Pibarot P, Evangelista A, Bax JJ, Delgado V
Background: Significant (moderate or greater) mitral regurgitation (MR) could augment the hemodynamic effects of aortic valvular disease in patients with bicuspid aortic valve (BAV), imposing a greater hemodynamic burden on the left ventricle and atrium, possibly culminating in a faster onset of left ventricular dilation and/or symptoms. The aim of this study was to determine the prevalence and prognostic implications of significant MR in patients with BAV. Methods: In this large, multicenter, i... Abstract
Cited 1 times since 2022 (0.7 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 12, 1 1 2022, Pages 1708-1716 Detailed behaviour of endothelial wall shear stress across coronary lesions from non-invasive imaging with coronary computed tomography angiography. van den Hoogen IJ, Schultz J, Kuneman JH, de Graaf MA, Kamperidis V, Broersen A, Jukema JW, Sakellarios A, Nikopoulos S, Kyriakidis S, Naka KK, Michalis L, Fotiadis DI, Maaniitty T, Saraste A, Bax JJ, Knuuti J
Aims: Evolving evidence suggests that endothelial wall shear stress (ESS) plays a crucial role in the rupture and progression of coronary plaques by triggering biological signalling pathways. We aimed to investigate the patterns of ESS across coronary lesions from non-invasive imaging with coronary computed tomography angiography (CCTA), and to define plaque-associated ESS values in patients with coronary artery disease (CAD). Methods and results: Symptomatic patients with CAD who underwent a cl... Abstract
European heart journal. Cardiovascular Imaging, Volume 23, Issue 12, 1 1 2022, Pages 1596-1597 Cognitive implications of subclinical leaflet thrombosis after transcatheter aortic valve implantation. van der Bijl P, Bax JJ
Cited 4 times since 2022 (2.7 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 12, 1 1 2022, Pages 1669-1679 Left ventricular remodelling in bicuspid aortic valve disease. Butcher SC, Pio SM, Kong WKF, Singh GK, Ng ACT, Perry R, Sia CH, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Galian Gay L, Fijałkowski M, Liang M, Tay E, Ajmone Marsan N, Selvanayagam J, Pinto F, Zamorano JL, Pibarot P, Evangelista A, Bax JJ, Delgado V
Aims: Characterization of left ventricular (LV) geometric pattern and LV mass could provide an important insight into the pathophysiological adaptations of the LV to pressure and/or volume overload in patients with bicuspid aortic valve (BAV) and significant (≥moderate) aortic valve (AV) disease. This study aimed to characterize LV remodelling and its prognostic impact in patients with BAV according to the predominant type of valvular dysfunction. Methods and results: In this international, mult... Abstract
The American journal of cardiology, Volume 186, 29 5 2022, Pages 176-180 Prognostic Value of Nonalcoholic Fatty Liver Disease in Patients With Severe Aortic Stenosis Who Underwent Transcatheter Aortic Valve Implantation. Nabeta T, Myagmardorj R, Hirasawa K, Singh GK, van der Kley F, de Weger A, Knuuti J, Bax JJ, Marsan NA, Delgado V
Nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular events. Although the association between NAFLD and aortic valve sclerosis has been described, the prevalence and prognostic implications of NAFLD among patients with severe aortic stenosis (AS) have not been described. In addition, the effect of the presence of severe tricuspid regurgitation (TR) on the prevalence of NAFLD remains unexplored. Accordingly, we investigated the prognostic implications of... Abstract
Cited 4 times since 2022 (2.7 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 39, Issue 2, 28 4 2022, Pages 379-390 Impact of body mass index and diabetes on myocardial fat content, interstitial fibrosis and function. Dong X, Strudwick M, Wang WY, Borlaug BA, van der Geest RJ, Ng AC, Delgado V, Bax JJ, Ng AC
Purpose: We hypothesize that both increased myocardial steatosis and interstitial fibrosis contributes to subclinical myocardial dysfunction in patients with increased body mass index and diabetes mellitus. Background: Increased body weight and diabetes mellitus are both individually associated with a higher incidence of heart failure with preserved ejection fraction. However, it is unclear how increased myocardial steatosis and interstitial fibrosis interact to influence myocardial composition... Abstract
The international journal of cardiovascular imaging, Volume 39, Issue 2, 18 3 2022, Pages 441-450 Coronary computed tomography angiography-based endothelial wall shear stress in normal coronary arteries. Schultz J, van den Hoogen IJ, Kuneman JH, de Graaf MA, Kamperidis V, Broersen A, Jukema JW, Sakellarios A, Nikopoulos S, Tsarapatsani K, Naka K, Michalis L, Fotiadis DI, Maaniitty T, Saraste A, Bax JJ, Knuuti J
Endothelial wall shear stress (ESS) is a biomechanical force which plays a role in the formation and evolution of atherosclerotic lesions. The purpose of this study is to evaluate coronary computed tomography angiography (CCTA)-based ESS in coronary arteries without atherosclerosis, and to assess factors affecting ESS values. CCTA images from patients with suspected coronary artery disease were analyzed to identify coronary arteries without atherosclerosis. Minimal and maximal ESS values were ca... Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 30, Issue 2, 13 2 2022, Pages 748-750 Imaging phenotypes and outcomes after revascularization in chronic coronary artery disease. Saraste A, Bax JJ
Cited 1 times since 2022 (0.6 per year) source: EuropePMC
The American journal of cardiology, Volume 185, 11 2 2022, Pages 53-62 Factors Affecting Rate of Progression of Aortic Stenosis and Its Impact on Outcomes. Amanullah MR, Pio SM, Sin KYK, Marsan NA, Ding ZP, Stassen J, Leon MB, Genereux P, Delgado V, Ewe SH, Bax JJ
The rate of aortic stenosis (AS) progression in patients with moderate AS is unclear. This study examined the risk factors of progression from moderate to severe AS and its impact on clinical outcomes. A total of 954 patients with moderate AS (valve area >1.0 and ≤1.5 cm²) and follow-up echocardiograms were included. AS progressed to severe (valve area Abstract
Cited 3 times since 2022 (1.9 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 11, 1 1 2022, Pages 1540-1551 Prognostic implications of mitral valve geometry in patients with secondary mitral regurgitation: the COAPT trial. Namazi F, Delgado V, Delgado V, Pio SM, Ajmone Marsan N, Asch FM, Medvedofsky D, Weissman NJ, Zhou Z, Redfors B, Lindenfeld J, Abraham WT, Mack MJ, Stone GW, Bax JJ
Aims: The impact of mitral valve geometry on outcomes after MitraClip treatment in secondary mitral regurgitation (MR) has not been examined. We therefore sought to evaluate the association between mitral valve geometry and outcomes of patients with heart failure (HF) and secondary MR treated with guideline-directed medical therapy (GDMT) and MitraClip. Methods and results: Mitral valve geometry was assessed from the baseline echocardiograms in 614 patients from the COAPT trial. The primary endp... Abstract
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 63, Issue 10, 1 1 2022, Pages 1455-1458 Integrating Nuclear Imaging and Cardiology in Clinical Practice: A Conversation Between Jeroen J. Bax and Frank M. Bengel. Bax JJ, Bengel FM
European heart journal. Cardiovascular Imaging, Volume 23, Issue 11, 1 1 2022, Pages 1457-1458 Using deep learning to diagnose pulmonary hypertension. van der Bijl P, Bax JJ
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 36, Issue 1, 27 4 2022, Pages 128-129 Response to "Why Are Bicuspid Aortic Valve Patients Flying Under the Radar?" Stassen J, Bax JJ
Cited 2 times since 2022 (1.3 per year) source: EuropePMC
The American journal of cardiology, Volume 184, 23 4 2022, Pages 63-71 Impact of Worsening Heart Failure on Long-Term Prognosis in Patients With Heart Failure With Reduced Ejection Fraction. Chimed S, Stassen J, Galloo X, Meucci MC, van der Bijl P, Knuuti J, Delgado V, Marsan NA, Bax JJ
Worsening heart failure (HF), defined as hospitalization for worsening signs and symptoms of HF or the need for urgent intravenous diuretics, is often considered a surrogate of poor prognosis in clinical trials. However, data on the prognostic implications of worsening HF in patients with HF and reduced ejection fraction is limited. Patients who had a first echocardiographic diagnosis of left ventricular systolic dysfunction, defined as left ventricular ejection fraction (LVEF) ≤45%, were identi... Abstract
Cited 9 times since 2022 (5.6 per year) source: EuropePMC
Circulation. Cardiovascular interventions, Volume 15, Issue 9, 20 3 2022, Pages e011958 Atrial Functional Tricuspid Regurgitation: Novel Definition and Impact on Prognosis. Schlotter F, Dietz MF, Stolz L, Kresoja KP, Besler C, Sannino A, Rommel KP, Unterhuber M, von Roeder M, Delgado V, Thiele H, Hausleiter J, Bax JJ, Lurz P
Background: Atrial functional tricuspid regurgitation (atrial TR) has received growing recognition as a TR entity with a distinct cause owing to its independence from valvular tethering as the predominant mechanism underlying TR. However, characterization of atrial TR varies, and a universal definition is lacking. Methods: In total, 651 patients with significant functional TR were analyzed, including 438 conservatively treated individuals and 213 patients who received transcatheter tricuspid val... Abstract
Journal of diabetes and its complications, Volume 36, Issue 12, 15 3 2022, Pages 108309 Extent of subclinical atherosclerosis on coronary computed tomography and impact of statins in patients with diabetes without known coronary artery disease: Results from CONFIRM registry. Shaikh K, Ahmed A, Gransar H, Lee J, Leipsic J, Nakanishi R, Alla V, Bax JJ, Chow BJW, Berman DS, Maffei E, Lin FY, Ahmad A, DeLago A, Pontone G, Feuchtner G, Marques H, Min JK, Hausleiter J, Hadamitzky M, Kaufmann PA, de Araújo Gonçalves P, Cury RC, Kim YJ, Chang HJ, Rubinshtein R, Villines TC, Lu Y, Shaw LJ, Acenbach S, Al Mallah MH, Andreini D, Cademartiri F, Callister TQ, Budoff MJ
Background: Absence of subclinical atherosclerosis is considered safe to defer statin therapy in general population. However, impact of statins on atherosclerotic cardiovascular disease in patients with diabetes stratified by coronary artery calcium (CAC) scores and extent of non-obstructive CAD on coronary computed tomography angiography (CCTA) has not been evaluated. Methods: CONFIRM (Coronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multi-center Registry) study enroll... Abstract
Cited 2 times since 2022 (1.2 per year) source: EuropePMC
The American journal of cardiology, Volume 183, 14 2 2022, Pages 33-39 Effect of Bi-Atrial Size and Function in Patients With Paroxysmal or Permanent Atrial Fibrillation. Bax M, Ajmone Marsan N, Delgado V, Bax JJ, van der Bijl P
Atrial fibrillation (AF) remains the most common arrhythmia in clinical practice. The choice between a rate-control and rhythm-control strategy depends on various factors, including the anatomical and functional substrate. This study investigates the anatomical and functional characteristics of both atria in patients with AF and explores the potential therapeutic implications. From an ongoing registry of patients with paroxysmal or permanent AF, those who underwent cardiac computed tomography (C... Abstract
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 36, Issue 2, 13 2 2022, Pages 252-254 Left Ventricular Myocardial Work to Differentiate Cardiac Amyloidosis From Hypertrophic Cardiomyopathy. Stassen J, Tjahjadi C, Adam R, Debonnaire P, Claeys M, Popescu BA, Jurcut R, Delgado V, Bax JJ, Marsan NA