Cited 44 times since 2008 (2.8 per year) source: EuropePMC Pacing and clinical electrophysiology : PACE, Volume 31, Issue 11, 1 1 2008, Pages 1475-1499 Noninvasive imaging in cardiac resynchronization therapy--part 1: selection of patients. Ypenburg C, Westenberg JJ, Bleeker GB, VAN de Veire N, Marsan NA, Henneman MM, van der Wall EE, Schalij MJ, Abraham TP, Barold SS, Bax JJ

Cardiac resynchronization therapy (CRT) is an established therapy for patients with advanced heart failure, depressed left ventricular function, and wide QRS complex. However, individual response varies, and a substantial amount of patients do not respond to CRT. Recent studies observed that assessment of inter- and particularly intraventricular dyssynchrony may allow identification of potential responders to CRT. In addition, presence of scar tissue and venous anatomy may play a role in the selection of candidates. In this review, an extensive overview of the available dyssynchrony measurements is provided using echocardiography as well as magnetic resonance imaging (MRI) and nuclear imaging. Furthermore, other information derived from MRI, nuclear imaging, and computed tomography useful for the selection of potential candidates for CRT will be discussed.

Pacing Clin Electrophysiol. 2008 11;31(11):1475-1499