Cited 6 times since 2000 (0.3 per year) source: EuropePMC The American journal of cardiology, Volume 86, Issue 7, 1 1 2000, Pages 774-6, A6 Effect of simvastatin on restenosis after percutaneous transluminal angioplasty of femoropopliteal arterial obstruction. Hagenaars T, Gussenhoven EJ, van Sambeek MR, Jukema JW, Kranendonk SE, Bom N
This retrospective observational intravascular ultrasound study evaluated whether simvastatin therapy limits lumen area reduction 1-year after percutaneous transluminal angioplasty (PTA) by reducing reactive plaque growth, reducing reactive vasoconstriction, or both. This study showed that plaque growth is a general response 1 year after PTA regardless of the use of simvastatin; simvastatin has the potential to induce positive vascular remodeling, thereby reducing the occurrence of restenosis.
