Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
194 results
Cited 12 times since 2005 (0.6 per year) source: EuropePMC
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, Volume 14, Issue 1, 1 1 2005, Pages 57-69 Perspectives on quality of life of people with intellectual disabilities: the interpretation of discrepancies between clients and caregivers. Janssen CG, Schuengel C, Stolk J
Large discrepancies have sometimes been found between the quality of life (QOL) experienced by clients with intellectual disabilities and their QOL as described by their caregivers. Olsen and Schober (Soc Indi Res 1993; 28: 173-193) may have provided a framework useful to conceptualize such discrepancies. They suggested that lack of concordance between objective circumstances (i.e. poverty) and perceived QOL must not be treated as measurement noise, but as a source of information. They speculate... Abstract
Cited 4 times since 2005 (0.2 per year) source: EuropePMC
Thorax, Volume 60, Issue 1, 1 1 2005, Pages 84; author reply 84 High dose intravenous AAT and plasma neutrophil derived fibrinogen fragments. Stolk J, Nieuwenhuizen W, Stoller JK, Aboussouan L
Cited 13 times since 2005 (0.7 per year) source: EuropePMC
Pneumologie (Stuttgart, Germany), Volume 59, Issue 1, 1 1 2005, Pages 36-68 [American Thoracic Society/European Respiratory Society Statement: Standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency]. Stoller JK, Snider GL, Brantly ML, Fallat RJ, Stockley RA, Turino GM, Konietzko N, Dirksen A, Eden E, Fallat RJ, Luisetti M, Stolk J, Strange C, American Thoracic Society, European Respiratory Society
Cited 17 times since 2004 (0.9 per year) source: EuropePMC
Thorax, Volume 59, Issue 11, 1 1 2004, Pages 986-991 Alpha1-antitrypsin deficiency. 7: Computed tomographic imaging in alpha1-antitrypsin deficiency. Shaker SB, Stavngaard T, Stolk J, Stoel B, Dirksen A
Computed tomographic scanning may replace lung function tests as the golden standard for assessing the response to known and novel treatments for alpha1-antitrypsin deficiency. Abstract
Cited 61 times since 2004 (3.1 per year) source: EuropePMC
Investigative radiology, Volume 39, Issue 11, 1 1 2004, Pages 681-688 Optimization and standardization of lung densitometry in the assessment of pulmonary emphysema. Stoel BC, Stolk J
Currently, lung densitometry for the assessment of pulmonary emphysema has been fully validated against pathology, pulmonary function, and health status, and it is therefore being applied in pharmacotherapeutic trials. Nevertheless, its application for the early detection of emphysema has not yet been introduced in daily clinical practice. The main reason for this is the fact that it is not yet regarded a fully optimized and standardized technique. In this work, an overview is given on the curre... Abstract
Cited 111 times since 2004 (5.6 per year) source: EuropePMC
American journal of respiratory and critical care medicine, Volume 170, Issue 11, 11 2 2004, Pages 1172-1178 Pattern of emphysema distribution in alpha1-antitrypsin deficiency influences lung function impairment. Parr DG, Stoel BC, Stolk J, Stockley RA
FEV(1) is fundamental to the diagnosis and staging of chronic obstructive pulmonary disease. In emphysema, airflow obstruction usually coexists with impairment of gas exchange, but discordance is not infrequent. We hypothesized that variations in the distribution of emphysema would be associated with functional differences and therefore account for discordant physiology. We used quantitative computed tomography to assess emphysema severity and distribution in 119 subjects with alpha1-antitrypsin... Abstract
Cited 63 times since 2004 (3.2 per year) source: EuropePMC
American journal of respiratory and critical care medicine, Volume 170, Issue 8, 21 3 2004, Pages 883-890 Influence of calibration on densitometric studies of emphysema progression using computed tomography. Parr DG, Stoel BC, Stolk J, Nightingale PG, Stockley RA
The fundamental importance of calibration for any measuring device is indisputable, but computed tomography (CT) calibration in longitudinal lung densitometry studies is largely unexplored. Although the validity of CT as a measure of emphysema has been confirmed in cross-sectional studies, there are limited data on long-term reproducibility, and this is critically important for validating its use as an outcome measure in therapeutic trials. A general understanding of the strengths and pitfalls o... Abstract
Cited 65 times since 2004 (3.3 per year) source: EuropePMC
American journal of respiratory and critical care medicine, Volume 170, Issue 5, 1 1 2004, Pages 499-504 Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease. Lapperre TS, Snoeck-Stroband JB, Gosman MM, Stolk J, Sont JK, Jansen DF, Kerstjens HA, Postma DS, Sterk PJ, Groningen and Leiden Universities Corticosteroids in Obstructive Lung Disease Study Group
Chronic obstructive pulmonary disease (COPD) is defined by progressive, irreversible airflow limitation and an inflammatory response of the lungs, usually to cigarette smoke. However, COPD is a heterogeneous disease in terms of clinical, physiologic, and pathologic presentation. We aimed to evaluate whether airflow limitation, airway responsiveness, and airway inflammation are separate entities underlying the pathophysiology of COPD by using factor analysis. A total of 114 patients (99 males/15... Abstract
Cited 8 times since 2004 (0.4 per year) source: EuropePMC
Inflammation research : official journal of the European Histamine Research Society ... [et al.], Volume 53, Issue 6, 12 2 2004, Pages 230-238 Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous metaplastic epithelium of bronchial airways. Aarbiou J, van Schadewijk A, Stolk J, Sont JK, de Boer WI, Rabe KF, van Krieken JH, Mauad T, Hiemstra PS
Objective: The aim of this study was to analyze a possible contribution of human neutrophil defensins and secretory leukocyte proteinase inhibitor (SLPI) to the induction of airway epithelial changes such as squamous cell metaplasia. Materials and methods: The presence of these molecules and the number of proliferating (Ki-67-positive) epithelial cells was analyzed by immunohistochemistry in bronchial epithelium from subjects with (n = 15) or without (n = 14) chronic obstructive pulmonary diseas... Abstract
Cited 14 times since 2004 (0.7 per year) source: EuropePMC
Journal of biomechanics, Volume 37, Issue 1, 1 1 2004, Pages 13-26 Modelling the fibrous tissue layer in cemented hip replacements: experimental and finite element methods. Waide V, Cristofolini L, Stolk J, Verdonschot N, Boogaard GJ, Toni A
The long-term fixation of cemented femoral components may be jeopardised by the presence of a fibrous tissue layer at the bone-cement interface. This study used both experimental and finite element (FE) methods to investigate the load transfer characteristics of two types of cemented hip replacements (Lubinus SPII and Müller-Curved) with a fibrous tissue layer. The experimental part investigated six stems of each type, where these were implanted in composite femurs with a specially selected sili... Abstract
Cited 33 times since 2004 (1.6 per year) source: EuropePMC
Investigative radiology, Volume 39, Issue 1, 1 1 2004, Pages 1-7 Comparison of the sensitivities of 5 different computed tomography scanners for the assessment of the progression of pulmonary emphysema: a phantom study. Stoel BC, Bakker ME, Stolk J, Dirksen A, Stockley RA, Piitulainen E, Russi EW, Reiber JH
Rationale and objectives: To compare the sensitivities of 5 different computed tomography scanners (4 multislice CT [MSCT] and 1 single-slice CT) in the assessment of the progression of pulmonary emphysema. Methods: A Perspex cylinder phantom was constructed containing small pieces of polythene foam with densities representative of lung. Changing the cylinder's volume simulated subtle lung density changes. The sensitivity to density changes was defined by the variation in the residual error... Abstract
Cited 49 times since 2003 (2.4 per year) source: EuropePMC
Thorax, Volume 58, Issue 12, 1 1 2003, Pages 1027-1030 Correlation between annual change in health status and computer tomography derived lung density in subjects with alpha1-antitrypsin deficiency. Stolk J, Ng WH, Bakker ME, Reiber JH, Rabe KF, Putter H, Stoel BC
Background: There is increasing recognition that questionnaires of health status and lung density measurements are more sensitive tools for assessing progression of emphysema than forced expiratory volume in 1 second (FEV(1)) and transfer coefficient (KCO). A study was undertaken to investigate prospectively the correlation between annual change in health status and computer tomography (CT) derived lung density in subjects with alpha(1)-antitrypsin deficiency. Methods: Twenty two patients of mea... Abstract
Cited 19 times since 2003 (0.9 per year) source: EuropePMC
Clinical biomechanics (Bristol, Avon), Volume 18, Issue 6, 1 1 2003, Pages 523-536 Experimental investigation of bone remodelling using composite femurs. Waide V, Cristofolini L, Stolk J, Verdonschot N, Toni A
Objective: To determine the load transfer patterns of femurs in the intact, immediate post-operative and long-term (remodelled) post-operative implanted conditions for Lubinus SPII and Müller-Curved cemented hip prostheses, and to examine to what extent remodelling may influence the long-term outcome. Design: Experimental and finite element (FE) methods were applied to composite femurs under loads representing the heel-strike phase of gait, determining cortical bone and cement strains for the di... Abstract
Cited 8 times since 2003 (0.4 per year) source: EuropePMC
Journal of biomechanics, Volume 36, Issue 6, 1 1 2003, Pages 861-871 Prevention of mesh-dependent damage growth in finite element simulations of crack formation in acrylic bone cement. Stolk J, Verdonschot N, Mann KA, Huiskes R
Peak stress levels predicted in finite element analysis (FEA) usually depend on mesh density, due to singular points in the model. In an earlier study, an FEA algorithm was developed to simulate the damage accumulation process in the cement mantle around total hip replacement (THR) implants. It allows cement crack formation to be predicted, as a function of the local cement stress levels. As the simulation is driven by mesh-dependent peak stresses, predicted crack formation rates are also likely... Abstract
Cited 18 times since 2003 (0.9 per year) source: EuropePMC
Clinical orthopaedics and related research, Issue 409, 1 1 2003, Pages 138-150 Can finite element models detect clinically inferior cemented hip implants? Stolk J, Maher SA, Verdonschot N, Prendergast PJ, Huiskes R
Rigorous preclinical testing of cemented hip prostheses against the damage accumulation failure scenario will reduce the incidence of aseptic loosening. For that purpose, a finite element simulation is proposed that predicts damage accumulation in the cement mantle and prosthetic migration. If the simulation is to become a convincing preclinical test, it should be able to distinguish between implants in a clinically relevant way, based on accurate predictions of long-term failure mechanisms of c... Abstract
Cited 7 times since 2003 (0.3 per year) source: EuropePMC
Psychological medicine, Volume 33, Issue 3, 1 1 2003, Pages 511-518 Personality and symptom sensitivity predictors of alprazolam withdrawal in panic disorder. Roy-Byrne P, Russo J, Pollack M, Stewart R, Bystrisky A, Bell J, Rosenbaum J, Corrigan MH, Stolk J, Rush AJ, Ballenger J
Background: Discontinuation of benzodiazepine (BZ) treatment results in a well-characterized withdrawal syndrome in 40-50% of anxious patients. While numerous studies have established the role of BZ dose, treatment duration, half-life, potency, rate of withdrawal and severity of underling anxiety disorder in predicting severity of withdrawal symptoms, fewer studies have examined the role of psychological and personality factors. Method: In 123 panic disorder patients undergoing gradual tapered d... Abstract
Cited 3 times since 2003 (0.1 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 147, Issue 16, 1 1 2003, Pages 758-760 [From gene disease; alpha1-antitrypsine deficiency]. Hiemstra PS, Stolk J
Alpha-1-antitrypsin (alpha 1-AT) deficiency is an autosomal, recessive hereditary disorder that is associated with the development of pulmonary emphysema and liver disease. The most common mutant leading to the deficiency is the Z mutant. This results in alpha 1-AT that forms polymers which lead to accumulation in the liver and decreased secretion. Emphysema is thought to occur due to insufficient protection of the lung tissue from the proteolytic activity of neutrophil-derived elastase, as a re... Abstract
Cited 16 times since 2002 (0.7 per year) source: EuropePMC
Clinical orthopaedics and related research, Issue 405, 1 1 2002, Pages 294-305 Stair climbing is more detrimental to the cement in hip replacement than walking. Stolk J, Verdonschot N, Huiskes R
Stair climbing may be detrimental to cemented total hip arthroplasties, because it subjects the reconstruction to high torsional loads. The current study investigated how stair climbing contributes to damage accumulation in the cement around a femoral stem compared with walking, taking into account the different frequencies of these activities during patient functioning. In finite element analyses, the damage accumulation process in the cement mantle around a Lubinus SPII stem was simulated for... Abstract
Cited 7 times since 2002 (0.3 per year) source: EuropePMC
Clinical orthopaedics and related research, Issue 404, 1 1 2002, Pages 353-361 Effects of metal-inlay thickness in polyethylene cups with metal-on-metal bearings. Verdonschot N, Vena P, Stolk J, Huiskes R
A way to prevent polyethylene wear in total hip replacements is to use metal-on-metal bearings. The cup design of these bearings may be a metal inlay in a polyethylene cup. However, these metal inlays are relatively thin and may deform on loading. The purpose of the current study was to determine whether these potential problems become actual for a realistic range of metal-inlay components having a thickness greater than 1 mm. For this purpose, the effects of thickness variation of a metal inlay... Abstract
Cited 3 times since 2002 (0.1 per year) source: EuropePMC
Acta orthopaedica Belgica, Volume 68, Issue 4, 1 1 2002, Pages 348-355 Do unloading periods affect migration characteristics of cemented femoral components? An in vitro evaluation with the Exeter stem. Verdonschot N, Barink M, Stolk J, Gardeniers JW, Schreurs BW
Prosthetic migration has been identified as a marker for future revision of cemented total hip reconstructions. This could be tested at a pre-clinical stage with dynamic loading experiments. The purpose of this study was to assess the effects of resting periods, which are a considerable part of the daily activity cycle, on the migration characteristics of femoral cemented stems. Ten polished Exeter stems were implanted in composite femurs and loaded either with a continuous load or a discontinuo... Abstract