Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
44 results
Cited 18 times since 2010 (1.3 per year) source: EuropePMC
Tissue engineering. Part C, Methods, Volume 16, Issue 4, 1 1 2010, Pages 597-607 Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study. Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer JE, Aikawa E
Objectives: Creating functional small-diameter tissue-engineered blood vessels has not been successful to date. Moreover, the processes underlying the in vivo remodeling of these grafts and the fate of cells seeded onto scaffolds remain unclear. Here we addressed these unmet scientific needs by using intravital molecular imaging to monitor the development of tissue-engineered vascular grafts (TEVG) implanted in mouse carotid artery. Methods and results: Green fluorescent protein-labeled human bo... Abstract
Cited 119 times since 2010 (8.6 per year) source: EuropePMC
European heart journal, Volume 31, Issue 16, 2 1 2010, Pages 1975-1984 Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E
Aims: Westernized countries face a growing burden of cardiovascular calcification and osteoporosis. Despite its vast clinical significance, the precise nature of this reciprocal relationship remains obscure. We hypothesize that cardiovascular calcification progresses with inflammation and inversely correlates with bone tissue mineral density (TMD). Methods and results: Arterial, valvular, and bone metabolism were visualized using near-infrared fluorescence (NIRF) molecular imaging agents, target... Abstract
Cited 16 times since 2009 (1.1 per year) source: EuropePMC
Tissue engineering. Part B, Reviews, Volume 15, Issue 3, 1 1 2009, Pages 307-317 Translating autologous heart valve tissue engineering from bench to bed. Hjortnaes J, Bouten CV, Van Herwerden LA, Gründeman PF, Kluin J
Tissue engineering is currently being actively investigated to ascertain if it can offer an alternative to prosthetic aortic heart valves that may overcome the current limitations of prosthetic aortic heart valves while at the same time conferring the advantages of a living autologous structure, such as biocompatibility, the capacity to grow, repair, and remodel. In vitro studies have shown tissue-engineered heart valves to have adequate structural and functional properties, indicating a promisi... Abstract
Cited 30 times since 2007 (1.8 per year) source: EuropePMC
The Journal of rheumatology, Volume 34, Issue 9, 1 1 2007, Pages 1882-1887 Serum uric acid levels and risk for vascular diseases in patients with metabolic syndrome. Hjortnaes J, Algra A, Olijhoek J, Huisman M, Jacobs J, van der Graaf Y, Visseren F
Objective: Gout and increased serum uric acid (SUA) levels are often seen in patients with components of the metabolic syndrome. Increased SUA levels are associated with increased vascular risk, as is the metabolic syndrome. We investigated the association between SUA levels and the metabolic syndrome in a population of patients with manifest vascular disease to determine whether SUA levels convey an independent risk for vascular disease in patients with the metabolic syndrome. Methods: A nested... Abstract