Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
248 results
Cited 26 times since 1990 (0.8 per year) source: EuropePMC
International journal of cancer, Volume 45, Issue 1, 1 1 1990, Pages 16-20 Frequency and degree of aneuploidy in benign and malignant thyroid neoplasms. Schelfhout LJ, Cornelisse CJ, Goslings BM, Hamming JF, Kuipers-Dijkshoorn NJ, van de Velde CJ, Fleuren GJ
The frequency and degree of aneuploidy in 44 benign and 124 malignant thyroid neoplasms were analyzed by DNA flow cytometry. Single aneuploid cell populations were found in 72% of the undifferentiated carcinomas, 64% of the follicular carcinomas, 24% of the papillary carcinomas and in 24% of the follicular adenomas. Multiple aneuploid cell populations were detected in 4% of the papillary and in 36% of the follicular carcinomas but not in undifferentiated carcinomas. A low degree of aneuploidy wa... Abstract
Cited 82 times since 1990 (2.4 per year) source: EuropePMC
Archives of internal medicine, Volume 150, Issue 1, 1 1 1990, Pages 113-116 The value of fine-needle aspiration biopsy in patients with nodular thyroid disease divided into groups of suspicion of malignant neoplasms on clinical grounds. Hamming JF, Goslings BM, van Steenis GJ, van Ravenswaay Claasen H, Hermans J, van de Velde CJ
The accuracy of clinical diagnosis and fine-needle aspiration biopsy (FNAB) was evaluated in 169 patients surgically treated for nodular thyroid disease. Patients were divided into three groups with high, moderate, or low suspicion of malignant neoplasms on clinical grounds without previous knowledge of cytologic or histologic results. Histologic examination revealed an overall malignant neoplasm rate of 23%; the rate was 71%, 14%, and 11% for the groups with high, moderate, and low suspicion, r... Abstract
Cited 18 times since 1989 (0.5 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 25, Issue 9, 1 1 1989, Pages 1317-1323 Prognosis and morbidity after total thyroidectomy for papillary, follicular and medullary thyroid cancer. Hamming JF, Van de Velde CJ, Goslings BM, Schelfhout LJ, Fleuren GJ, Hermans J, Zwaveling A
The prognosis and the morbidity results after total thyroidectomy are reported for 148 patients with differentiated thyroid cancer. Ninety-two patients (62%) had papillary cancer, 27 (18%) had follicular cancer and 29 (20%) had medullary cancer. In the latter group, 16 patients had no clinical signs of a tumour and underwent total thyroidectomy after elevated calcitonin levels were found in a family screening programme. The mean follow-up period was 9.7 years in the present series. The 5- and 10... Abstract
Cited 17 times since 1989 (0.5 per year) source: EuropePMC
Surgery, gynecology & obstetrics, Volume 169, Issue 2, 1 1 1989, Pages 107-114 Peroperative diagnosis and treatment of metastases to the regional lymph nodes in papillary carcinoma of the thyroid gland. Hamming JF, van de Velde CJ, Goslings BM, Fleuren GJ, Hermans J, Delemarre JF, van Slooten EA
The management of two groups of patients with papillary carcinoma of the thyroid gland (n = 165) was evaluated retrospectively. Total thyroidectomy was the standard procedure in both groups, but the peroperative diagnosis and treatment of metastases to the regional lymph nodes differed. In group 1 (n = 84), only clinically positive lymph nodes were resected, and if residual postoperative 131I uptake was found, an ablation dose of 131I was given. In group 2 (n = 81), all of the tissue in the trac... Abstract
Cited 1 times since 1989 (0 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 133, Issue 10, 1 1 1989, Pages 494-498 [Diagnosis and treatment of differentiated thyroid carcinoma]. Schelfhout LJ, Goslings BM, Hamming JF, Bruining HA, Krenning EP, van de Velde CJ
Cited 24 times since 1988 (0.7 per year) source: EuropePMC
World journal of surgery, Volume 12, Issue 4, 1 1 1988, Pages 503-508 Prognostic value of nuclear DNA content in papillary and follicular thyroid cancer. Hamming JF, Schelfhout LJ, Cornelisse CJ, van de Velde CJ, Goslings BM, Hermans J, Fleuren GJ
Cited 17 times since 1988 (0.5 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 24, Issue 2, 1 1 1988, Pages 325-330 Differentiated thyroid cancer: a stage adapted approach to the treatment of regional lymph node metastases. Hamming JF, van de Velde CJ, Fleuren GJ, Goslings BM
The controversy in the management of regional lymph nodes in patients with differentiated thyroid cancer is discussed on the basis of a review of the literature. Since no prospective studies have yet compared limited dissections ('node picking') with more extensive dissections [(modified) radical neck dissection], a retrospective analysis was performed using two patient groups in which patients were managed differently with regard to the preoperative diagnosis and treatment of regional... Abstract
Cited 58 times since 1988 (1.6 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 24, Issue 2, 1 1 1988, Pages 331-337 Multivariate analysis of survival in differentiated thyroid cancer: the prognostic significance of the age factor. Schelfhout LJ, Creutzberg CL, Hamming JF, Fleuren GJ, Smeenk D, Hermans J, van de Velde CJ, Goslings BM
A retrospective analysis of tumour and patient characteristics was performed in 202 patients with papillary (n = 132) or follicular (n = 70) thyroid carcinoma, in order to identify prognostic factors related to survival. The following facts were found to be unfavourably related to survival: follicular histology, extrathyroidal growth of the primary tumour (stage pT4), regional lymph node involvement (stages pN1-3), presence of distant metastases at diagnosis (stage pM1), male sex (in papillary c... Abstract