Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
111 results
Cited 3 times since 1996 (0.1 per year) source: EuropePMC
European journal of applied physiology and occupational physiology, Volume 73, Issue 1-2, 1 1 1996, Pages 113-116 Intravenous instrumentation alters the autonomic state in humans. Bootsma M, Swenne CA, Lenders JW, Jacobs MC, Bruschke AV
Intravascular instrumentation may induce syncope or presyncope. It is not known whether asymptomatic subjects also have autonomic reactions, albeit concealed. We addressed this issue by studying 44 healthy young male subjects of various levels of fitness, ranging from inactivity to athletic [mean maximal oxygen uptake was 49.1 (SD 10.7) ml*kg(-1)*min(-1), range 28.7-71.9 ml*kg(-1)*min(-1)]. The autonomic response to venous cannulation was quantified by measuring heart rate before cannulation (HR... Abstract
Cited 9 times since 1996 (0.3 per year) source: EuropePMC
Clinical cardiology, Volume 19, Issue 1, 1 1 1996, Pages 62-68 Heart rate variability during repeated incremental head-up tilt discloses time dependence of individual autonomic dynamics. Bootsma M, Swenne CA, Bruschke AV
According to the Rosenblueth-Simeone model, the heart rate (HR) is proportional to the sympathovagal balance. The individual proportionality constant is the intrinsic HR, which can be determined only invasively. The percentage low-frequency spectral HR variability power, relative to the low- plus high-frequency spectral power (%LF) has been raised as a noninvasive alternative. We previously studied young healthy male subjects, in whom gradual autonomic changes were induced by incremental head-up... Abstract
Clinical science (London, England : 1979), Volume 91 Suppl, 1 1 1996, Pages 113-115 Heart rate variability, baroreflex sensitivity, and cardiac vagal tone. Swenne CA, Bootsma M, Hyndman BW, Voogd J, Bruschke AV
Cited 2 times since 1995 (0.1 per year) source: EuropePMC
The American journal of cardiology, Volume 76, Issue 12, 1 1 1995, Pages 922-927 Similar orthostatic defense in active, healthy young adult and late middle-aged men. Bootsma M, Swenne CA, Bruschke AV
Orthostatic defense is commonly validated with a 60 degrees to 80 degrees head-up tilt test, addressing the step response rather than the response to permanent orthostatis. During the initial phase of tilt, neural factors predominate, while later, the slower humoral factors fade in. It has been demonstrated that, during adaptation of the circulatory system to the standing conditions, overshoot and undershoot occur. These oscillations hamper straight-forward interpretation of a tilt test, and may... Abstract
Cited 2 times since 1995 (0.1 per year) source: EuropePMC
Circulation, Volume 91, Issue 8, 1 1 1995, Pages 2292-2293 Sympathovagal balance and graded orthostatic tilt. Swenne CA, Bootsma M
Cited 78 times since 1994 (2.6 per year) source: EuropePMC
The American journal of physiology, Volume 266, Issue 4 Pt 2, 1 1 1994, Pages H1565-71 Heart rate and heart rate variability as indexes of sympathovagal balance. Bootsma M, Swenne CA, Van Bolhuis HH, Chang PC, Cats VM, Bruschke AV
According to the Rosenblueth-Simeone model, the heart rate (HR) is proportional to the sympathovagal balance. The individual proportionality constant is the intrinsic heart rate, which can only be determined invasively. The normalized low-frequency heart rate variability power (LF) has been raised as a calibrated noninvasive alternative. To concrete this assumption, we studied the individual LF-HR relation during incremental head-up tilt (0, 10, 20, 30, 40, 45, 50, 55, 60, 65, 70, 75, and 80 deg... Abstract
Cited 21 times since 1994 (0.7 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 23, Issue 1, 1 1 1994, Pages 82-91 Systemic and cardiac neuroendocrine activation and severity of myocardial ischemia in humans. Remme WJ, Kruyssen DA, Look MP, Bootsma M, de Leeuw PW
Objectives: The purpose of this study was to assess the effect of different degrees of ischemia on circulating and cardiac neurohormones and vasotone. Background: Neuroendocrine activation and subsequent systemic vasoconstriction may complicate ischemia. Whether this relates to severity of ischemia and subsequent cardiac dysfunction, and whether neurohormonal balance in the ischemic area changes, is unknown. Methods: Fifty-six normotensive patients with coronary artery disease were evaluated dur... Abstract
Cited 14 times since 1993 (0.4 per year) source: EuropePMC
The Anatomical record, Volume 235, Issue 1, 1 1 1993, Pages 74-86 Histological organization of the right and left atrioventricular valves of the chicken heart and their relationship to the atrioventricular Purkinje ring and the middle bundle branch. Lu Y, James TN, Bootsma M, Terasaki F
In the avian heart the right and left atrioventricular (AV) valves not only exhibit their own special anatomical characteristics, but they also are in close proximity to the conduction system. The right AV valve is a single, spiral plane of myocardium, in remarkable contrast to the fibrous structure characteristic of the mammalian tricuspid valve. A ring of Purkinje tissue encircles the avian right AV orifice and connects to the muscular valve. The chicken has no crista supraventricularis, its r... Abstract
Cited 12 times since 1991 (0.4 per year) source: EuropePMC
The American journal of cardiology, Volume 68, Issue 2, 1 1 1991, Pages 181-186 Systemic neurohumoral activation and vasoconstriction during pacing-induced acute myocardial ischemia in patients with stable angina pectoris. Remme WJ, de Leeuw PW, Bootsma M, Look MP, Kruijssen DA
To identify the effect of myocardial ischemia on systemic neurohormones and vascular resistance, 32 untreated, normotensive patients with coronary artery disease underwent incremental atrial pacing until angina. Arterial and coronary venous lactate and arterial values of catecholamines and angiotensin II were determined at control, at maximal pacing rates, and at 1, 2, 5 and 30 minutes after pacing. Based on pacing-induced ST-segment depression (greater than or equal to 0.1 mV) or myocardial lac... Abstract
Cited 4 times since 1990 (0.1 per year) source: EuropePMC
European heart journal, Volume 11 Suppl B, 1 1 1990, Pages 162-171 Neurohumoral activation during acute myocardial ischaemia. Effects of ACE inhibition. Remme WJ, Look MP, Bootsma M, Kruyssen HA, Verrostte JM, Krauss XH, van Hoogenhuyze DC, Storm CJ
ACE inhibition may be useful in several manifestations of ischaemic heart disease, such as heart failure due to ischaemic cardiomyopathy. Recent evidence suggests that these effects may also be present in normotensive patients with ischaemic heart disease without heart failure. Theoretically, converting-enzyme inhibition, through coronary and systemic vasodilating effects and negative inotropic properties, should have a favourable effect on the myocardial oxygen supply/demand ratio and, hence, a... Abstract
Cited 6 times since 1980 (0.1 per year) source: EuropePMC
Lancet (London, England), Volume 2, Issue 8206, 1 1 1980, Pages 1241-1242 Hepatitis A in non-human primates in nature. Smith MS, Swanepoel PJ, Bootsma M