Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
1722 results
Cited 9 times since 2022 (5.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 80, Issue 5, 1 1 2022, Pages 545-561 Standardized Definitions for Bioprosthetic Valve Dysfunction Following Aortic or Mitral Valve Replacement: JACC State-of-the-Art Review. Pibarot P, Herrmann HC, Wu C, Hahn RT, Otto CM, Abbas AE, Chambers J, Dweck MR, Leipsic JA, Simonato M, Rogers T, Sathananthan J, Guerrero M, Ternacle J, Wijeysundera HC, Sondergaard L, Barbanti M, Salaun E, Généreux P, Kaneko T, Landes U, Wood DA, Deeb GM, Sellers SL, Lewis J, Madhavan M, Gillam L, Reardon M, Bleiziffer S, O'Gara PT, Rodés-Cabau J, Grayburn PA, Lancellotti P, Thourani VH, Bax JJ, Mack MJ, Leon MB, Heart Valve Collaboratory
Bioprosthetic valve dysfunction (BVD) and bioprosthetic valve failure (BVF) may be caused by structural or nonstructural valve dysfunction. Both surgical and transcatheter bioprosthetic valves have limited durability because of structural valve deterioration. The main objective of this summary of experts participating in a virtual workshop was to propose standardized definitions for nonstructural and structural BVD and BVF following aortic or mitral biological valve replacement with the goal of... Abstract
Cited 1 times since 2022 (0.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 80, Issue 5, 1 1 2022, Pages 527-544 Bioprosthetic Aortic Valve Hemodynamics: Definitions, Outcomes, and Evidence Gaps: JACC State-of-the-Art Review. Herrmann HC, Pibarot P, Wu C, Hahn RT, Tang GHL, Abbas AE, Playford D, Ruel M, Jilaihawi H, Sathananthan J, Wood DA, De Paulis R, Bax JJ, Rodes-Cabau J, Cameron DE, Chen T, Del Nido PJ, Dweck MR, Kaneko T, Latib A, Moat N, Modine T, Popma JJ, Raben J, Smith RL, Tchetche D, Thomas MR, Vincent F, Yoganathan A, Zuckerman B, Mack MJ, Leon MB, Heart Valve Collaboratory
A virtual workshop was organized by the Heart Valve Collaboratory to identify areas of expert consensus, areas of disagreement, and evidence gaps related to bioprosthetic aortic valve hemodynamics. Impaired functional performance of bioprosthetic aortic valve replacement is associated with adverse patient outcomes; however, this assessment is complicated by the lack of standardization for labelling, definitions, and measurement techniques, both after surgical and transcatheter valve replacement.... Abstract
Cited 6 times since 2022 (3.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 80, Issue 7, 1 1 2022, Pages 666-676 Prevalence and Prognostic Implications of Discordant Grading and Flow-Gradient Patterns in Moderate Aortic Stenosis. Stassen J, Ewe SH, Singh GK, Butcher SC, Hirasawa K, Amanullah MR, Pio SM, Sin KYK, Ding ZP, Sia CH, Chew NWS, Kong WKF, Poh KK, Leon MB, Pibarot P, Delgado V, Marsan NA, Bax JJ
Background: The prognostic implications of discordant grading in severe aortic stenosis (AS) are well known. However, the prevalence of different flow-gradient patterns and their prognostic implications in moderate AS are unknown. Objectives: The purpose of this study was to investigate the occurrence and prognostic implications of different flow-gradient patterns in patients with moderate AS. Methods: Patients with moderate AS (aortic valve area >1.0 and ≤1.5 cm2) were identified and divided... Abstract
Cited 1 times since 2022 (0.6 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 38, Issue 12, 18 3 2022, Pages 2687-2693 Prognostic value of left atrial volume index in degenerative mitral stenosis. Yedidya I, Butcher SC, Stassen J, van der Bijl P, Ngiam JN, Chew NWS, Sia CH, Leow R, Li TY, Kong WKF, Poh KK, Kornowski R, Marsan NA, Delgado V, Bax JJ
Purpose: Degenerative mitral stenosis (DMS) is associated with a poor prognosis. Although mean transmitral gradient (TMG) has shown a good correlation with outcome, little is known about the association between other echocardiographic parameters and prognosis in patients with DMS. The current study aimed to evaluate the prognostic value of left atrial volume index (LAVI) in patients with DMS. Methods: A total of 155 patients with DMS (72[63-80] years, 67% female) were included. The population wa... Abstract
Cited 2 times since 2022 (1.1 per year) source: EuropePMC
Journal of cardiovascular development and disease, Volume 9, Issue 7, 18 3 2022, Pages 230 Left Atrial Remodeling after Mitral Valve Repair for Primary Mitral Regurgitation: Evolution over Time and Prognostic Significance. Stassen J, van Wijngaarden AL, Wu HW, Palmen M, Tomsic A, Delgado V, Bax JJ, Marsan NA
Left atrial (LA) dilatation is associated with worse outcomes in primary mitral regurgitation (MR). However, the effects of mitral valve repair on LA size and its prognostic implications are not well known. In the current study, LA volume index (LAVi) and LA reservoir strain (LASr) were evaluated immediately before and after surgery, and during long-term follow-up in 226 patients undergoing mitral valve repair for primary MR (age 62 ± 13 years, 66% male). Mean LAVi was reduced significantly afte... Abstract
Herzschrittmachertherapie & Elektrophysiologie, Volume 33, Issue 3, 16 3 2022, Pages 261-267 Imaging for risk stratification of sudden cardiac death. van der Bijl P, Bax JJ
Sudden cardiac death (SCD) can be effectively prevented with the use of implantable cardioverter-defibrillator (ICD). Current guidelines advocate an ICD for primary prevention in the presence of an left ventricular ejection fraction (LVEF) ≤ 35%. The majority of individuals that experience SCD, however, have an LVEF > 35%. Multimodality cardiac imaging has the ability to visualize the three factors responsible for arrhythmia-mediated SCD, namely substrate, trigger and modulator. Advances in c... Abstract
The American journal of cardiology, Volume 179, 15 3 2022, Pages 64-69 Effects of Left Bundle Branch Block and Pacemaker Implantation on Left Ventricular Systolic Function After Transcatheter Aortic Valve Implantation. Dolci G, Singh GK, Wang X, van der Kley F, de Weger A, Bootsma M, Ajmone Marsan N, Bax JJ, Delgado V
Permanent pacemaker implantation (PPI) and left bundle branch block (LBBB) frequency after transcatheter aortic valve implantation (TAVI) and their effect on left ventricular ejection fraction (LVEF) remain controversial. We evaluated the incidence of PPI and new-onset LBBB after TAVI and their impact on LVEF at 6-month follow-up. Moreover, the impact of right ventricular (RV) pacing burden on changes in LVEF after TAVI was analyzed. The electrocardiograms of 377 patients (age 80 ± 7 years, 52%... Abstract
The American journal of cardiology, Volume 178, 11 2 2022, Pages 106-111 Relation of Myocardial Work Indexes and Forward Flow Reserve in Patients With Significant Secondary Mitral Regurgitation Undergoing Transcatheter Mitral Valve Repair. Yedidya I, Stassen J, Butcher SC, Pio SM, Lustosa RP, van der Bijl P, Vo NM, Namazi F, Marsan NA, Delgado V, Bax JJ
Left ventricular (LV) myocardial work (LVMW) indexes have shown incremental value over LV ejection fraction and were found to have prognostic significance in patients with secondary mitral regurgitation. We therefore aimed to investigate the association between LVMW indexes and forward flow reserve in patients with secondary mitral regurgitation, treated with transcatheter edge-to-edge repair (TEER). LVMW indexes were evaluated at baseline and forward stroke volume index (FSVI) was evaluated at... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 8, 1 1 2022, Pages 1090-1097 Association between computed tomography-derived tricuspid annular dimensions and prognosis: insights from whole-beat computed tomography assessment. Hirasawa K, Fortuni F, van Rosendael PJ, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Tricuspid regurgitation (TR) has been associated with outcome in patients treated with transcatheter aortic valve implantation (TAVI). Tricuspid annulus (TA) dimensions are associated with TR. However, the TA is highly dynamic during the cardiac cycle, and the interaction between the TA dimensions, TR, and patient prognosis has never been evaluated. This study aimed to characterize the dynamics of the TA along with the cardiac cycle and its association with prognosis in patients undergoing... Abstract
JACC. Cardiovascular interventions, Volume 15, Issue 14, 1 1 2022, Pages 1491 Reply: Could Left Atrial Function Modify Outcomes After Transcatheter Edge-to-Edge Repair of the Mitral Valve? Yoon SH, Siegel RJ, Bax JJ, Makkar RR
Cited 3 times since 2022 (1.6 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 62, Issue 2, 1 1 2022, Pages ezac290 Staging right heart failure in patients with tricuspid regurgitation undergoing tricuspid surgery. Galloo X, Stassen J, Butcher SC, Meucci MC, Dietz MF, Mertens BJA, Prihadi EA, van der Bijl P, Ajmone Marsan N, Braun J, Bax JJ, Delgado V
Objectives: This study evaluated the prognostic value of staging right heart failure in patients with significant tricuspid regurgitation (TR) undergoing tricuspid valve (TV) surgery. Methods: Patients with significant TR who underwent TV surgery were divided into 4 right heart failure stages according to the presence of right ventricular (RV) dysfunction and clinical signs of right heart failure: stage 1 was defined as no RV dysfunction and no signs of right heart failure; stage 2 indicated RV... Abstract
European heart journal. Cardiovascular Imaging, Volume 23, Issue 8, 1 1 2022, Pages e301-e302 Discussion forum: it is time to assess left ventricular segmental remodelling in aortic stenosis. Stassen J, Bax JJ
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 30, Issue 1, 20 3 2022, Pages 251-253 Using a deep learning algorithm to score coronary artery calcium in myocardial perfusion imaging: A real opportunity or just a new hype? Stassen J, van der Bijl P, Bax JJ
Cited 8 times since 2022 (4.2 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 15, Issue 10, 15 3 2022, Pages 1760-1767 Association Between Changes in Perivascular Adipose Tissue Density and Plaque Progression. Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Kitslaar PH, Reiber JHC, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Background: The association between the change in vessel inflammation, as quantified by perivascular adipose tissue (PVAT) density, and the progression of coronary atherosclerosis remains to be determined. Objectives: The purpose of this study was to explore the association between the change in PVAT density and the progression of total and compositional plaque volume (PV). Methods: Patients were selected from a prospective multinational registry. Patients who underwent serial coronary computed... Abstract
Cited 4 times since 2022 (2.1 per year) source: EuropePMC
International journal of cardiology, Volume 363, 15 3 2022, Pages 87-93 Left atrioventricular coupling index in hypertrophic cardiomyopathy and risk of new-onset atrial fibrillation. Meucci MC, Fortuni F, Galloo X, Bootsma M, Crea F, Bax JJ, Marsan NA, Delgado V
Backgrounds: This study aimed to investigate the association between left atrioventricular coupling index (LACI) and the occurrence of atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). Methods: A total of 373 patients with HCM and no history of AF were evaluated by transthoracic echocardiography. LACI was defined by the ratio of left atrial (LA) end-diastolic volume divided by left ventricular (LV) end-diastolic volume. The cut-off value for LACI (≥40%) to identify LA-... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 177, 9 2 2022, Pages 90-99 Prognostic Implications of Change in Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Implantation. Kuneman JH, Butcher SC, Singh GK, Wang X, Hirasawa K, van der Kley F, Leon MB, Knuuti J, Pibarot P, Ajmone Marsan N, Delgado V, Bax JJ
Reduced left ventricular (LV) systolic function is associated with worse prognosis in patients with severe aortic stenosis (AS) treated with transcatheter aortic valve implantation (TAVI). We aimed to examine the changes in left ventricular ejection fraction (LVEF) after TAVI among patients with varying baseline LVEF. Moreover, variables associated with lack of LVEF improvement were identified and the association with long-term outcomes was investigated. A total of 560 patients (age 80 ± 7 years... Abstract
Cited 8 times since 2022 (4.2 per year) source: EuropePMC
The American journal of cardiology, Volume 177, 9 2 2022, Pages 151-161 Right Ventricular Myocardial Work Characterization in Patients With Pulmonary Hypertension and Relation to Invasive Hemodynamic Parameters and Outcomes. Butcher SC, Feloukidis C, Kamperidis V, Yedidya I, Stassen J, Fortuni F, Vrana E, Mouratoglou SA, Boutou A, Giannakoulas G, Playford D, Ajmone Marsan N, Bax JJ, Delgado V
Noninvasive evaluation of indexes of right ventricular (RV) myocardial work (RVMW) derived from RV pressure-strain loops may provide novel insights into RV function in precapillary pulmonary hypertension. This study was designed to evaluate the association between the indexes of RVMW and invasive parameters of right heart catheterization and all-cause mortality. Noninvasive analysis of RVMW was completed in 51 patients (mean age 58.1 ± 12.7 years, 31% men) with group I or group IV pulmonary hype... Abstract
Cited 2 times since 2022 (1 per year) source: EuropePMC
Clinical cardiology, Volume 45, Issue 8, 8 2 2022, Pages 873-881 Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease. Won KB, Park HB, Heo R, Lee BK, Lin FY, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Gonçalves PA, Leipsic JA, Lee SE, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Berman DS, Narula J, Bax JJ, Min JK, Chang HJ
Background: Atherosclerosis-related adverse events are commonly observed even in conditions with low cardiovascular (CV) risk. Longitudinal data regarding the association of normal systolic blood pressure maintenance (SBPmaintain ) with coronary plaque volume changes (PVC) has been limited in adults without traditional CV disease. Hypothesis: Normal SBPmaintain is important to attenuate coronary atherosclerosis progression in adults without baseline CV disease. Methods: We analyzed 95 adults (56... Abstract
Structural heart : the journal of the Heart Team, Volume 6, Issue 3, 8 2 2022, Pages 100042 Sex-Related Differences in Medically Treated Moderate Aortic Stenosis. Stassen J, Pio SM, Ewe SH, Amanullah MR, Hirasawa K, Butcher SC, Singh GK, Sin KYK, Ding ZP, Chew NWS, Sia CH, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Background: Recent data showed poor long-term survival in patients with moderate AS. Although sex differences in left ventricular (LV) remodeling and outcome are well described in severe AS, it has not been evaluated in moderate AS. Methods: In this retrospective, multicenter study, patients with a first diagnosis of moderate AS diagnosed between 2001 and 2019 were identified. Clinical and echocardiographic parameters were recorded at baseline and compared between men and women. Patients were fo... Abstract
Cited 59 times since 2022 (30.3 per year) source: EuropePMC
JAMA, Volume 327, Issue 23, 1 1 2022, Pages 2296-2305 Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The DECAAF II Randomized Clinical Trial. Marrouche NF, Wazni O, McGann C, Greene T, Dean JM, Dagher L, Kholmovski E, Mansour M, Marchlinski F, Wilber D, Hindricks G, Mahnkopf C, Wells D, Jais P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Akoum N, DECAAF II Investigators
Importance: Ablation of persistent atrial fibrillation (AF) remains a challenge. Left atrial fibrosis plays an important role in the pathophysiology of AF and has been associated with poor procedural outcomes. Objective: To investigate the efficacy and adverse events of targeting atrial fibrosis detected on magnetic resonance imaging (MRI) in reducing atrial arrhythmia recurrence in persistent AF. Design, setting, and participants: The Efficacy of Delayed Enhancement-MRI-Guided Fibrosis Ablation... Abstract