Cited 7 times since 2015 (0.8 per year) source: EuropePMC Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 11, 1 1 2015, Pages 539-545 Platypnoea-orthodeoxia syndrome, an underdiagnosed cause of hypoxaemia: four cases and the possible underlying mechanisms. Nassif M, Lu H, Konings TC, Bouma BJ, Vonk Noordegraaf A, Straver B, Blom NA, Clur SA, Backx AP, Groenink M, Boekholdt SM, Koolbergen DR, Hazekamp MG, Mulder BJ, de Winter RJ
Cardiac platypnoea-orthodeoxia syndrome (POS) is a position-dependent condition of dyspnoea and hypoxaemia due to right-to-left shunting. It often remains unrecognised in clinical practice, possibly because of its complex underlying pathophysiology. We present four consecutive patients with POS and patent foramen ovale (PFO) who underwent a successful percutaneous PFO closure, describe the mechanism of their POS and provide a review of the literature.
