Cited 32 times since 2006 (1.8 per year) source: EuropePMC Heart rhythm, Volume 3, Issue 12, 10 2 2006, Pages 1397-1403 Right ventricular pacing and the risk of heart failure in implantable cardioverter-defibrillator patients. Smit MD, Van Dessel PF, Nieuwland W, Wiesfeld AC, Tan ES, Anthonio RL, Van Erven L, Van Veldhuisen DJ, Van Gelder IC
Background
Right ventricular (RV) pacing in implantable cardioverter-defibrillator (ICD) patients may have detrimental effects on morbidity and mortality, in particular by inducing heart failure (HF).
Objective
We investigated whether RV pacing increases the risk of HF in an asymptomatic ICD population.
Methods
We evaluated all patients without symptomatic HF who received an ICD. The primary endpoint was the occurrence of HF, which was defined as new HF, hospitalization for HF, or death due to HF. The secondary endpoint was appropriate shocks.
Results
The study population consisted of 456 patients with mean left ventricular ejection fraction (LVEF) 40% +/- 13%. Mean follow-up was 31 +/- 22 months. Because of the bimodal distribution of pacing, patients were divided into two groups: paced
Conclusion
RV pacing was associated with an increased risk of HF in asymptomatic ICD patients, particularly in those with preexistent left ventricular dysfunction.
