Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
1723 results
European heart journal. Cardiovascular Imaging, Volume 24, Issue 3, 1 1 2023, Pages 327-335 Feature-tracking computed tomography left atrial strain and long-term survival after transcatheter aortic valve implantation. Hirasawa K, Singh GK, Kuneman JH, Gegenava T, van der Kley F, Hautemann D, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Aortic stenosis (AS) induces left atrial (LA) remodelling through the increase of left ventricular (LV) filling pressures. Peak LA longitudinal strain (PALS), reflecting LA reservoir function, has been proposed as a prognostic marker in patients with AS. Feature-tracking (FT) multi-detector computed tomography (MDCT) allows assessment of LA strain from MDCT data. The aim of this study is to investigate the association between PALS using FT MDCT and survival in patients with severe AS who u... Abstract
Cited 6 times since 2023 (4.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 81, Issue 8, 1 1 2023, Pages 743-752 Cardiac Damage and Quality of Life After Aortic Valve Replacement in the PARTNER Trials. Généreux P, Cohen DJ, Pibarot P, Redfors B, Bax JJ, Zhao Y, Prince H, Makkar RR, Kapadia S, Thourani VH, Mack MJ, Nazif TM, Lindman BR, Babaliaros V, Russo M, McCabe JM, Gillam LD, Alu MC, Hahn RT, Webb JG, Leon MB, Arnold SV
Background: The extent of extravalvular cardiac damage is associated with increased risk of adverse events among patients with severe aortic stenosis undergoing aortic valve replacement (AVR). Objectives: The goal was to describe the association of cardiac damage on health status before and after AVR. Methods: Patients from the PARTNER (Placement of Aortic Transcatheter Valves) 2 and 3 trials were pooled and classified by echocardiographic cardiac damage stage at baseline and 1 year as previousl... Abstract
Cited 3 times since 2023 (2.3 per year) source: EuropePMC
Rheumatology (Oxford, England), Volume 62, Issue SI, 1 1 2023, Pages SI20-SI31 Evaluation of left cardiac chamber function with cardiac magnetic resonance and association with outcome in patients with systemic sclerosis. Butcher SC, Vos JL, Fortuni F, Galloo X, Liem SIE, Bax JJ, Delgado V, Vonk MC, van Leuven SI, Snoeren M, El Messaoudi S, de Vries-Bouwstra JK, Nijveldt R, Ajmone Marsan N
Objective: This study aimed to determine whether lower values of feature-tracking cardiovascular magnetic resonance (CMR)-derived left atrial reservoir strain (LARS) and impaired left ventricular (LV) global longitudinal strain (GLS) were associated with the presence of symptoms and long-term prognosis in patients with SSc. Methods: A total of 100 patients {54 [interquartile range (IQR) 46-64] years, 42% male} with SSc who underwent CMR imaging at two tertiary referral centres were included. All... Abstract
Cited 1 times since 2023 (0.8 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 16, Issue 2, 25 4 2023, Pages e011676 Prognostic Implications of Right Ventricular Size and Function in Patients Undergoing Cardiac Resynchronization Therapy. Galloo X, Stassen J, Hirasawa K, Mertens BJA, Cosyns B, van der Bijl P, Delgado V, Ajmone Marsan N, Bax JJ
Cited 1 times since 2023 (0.8 per year) source: EuropePMC
Clinical cardiology, Volume 46, Issue 3, 24 4 2023, Pages 320-327 Risk factors based vessel-specific prediction for stages of coronary artery disease using Bayesian quantile regression machine learning method: Results from the PARADIGM registry. Park HB, Lee J, Hong Y, Byungchang S, Kim W, Lee BK, Lin FY, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Gonçalves PA, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Kook W, Chang HJ
Background and hypothesis: The recently introduced Bayesian quantile regression (BQR) machine-learning method enables comprehensive analyzing the relationship among complex clinical variables. We analyzed the relationship between multiple cardiovascular (CV) risk factors and different stages of coronary artery disease (CAD) using the BQR model in a vessel-specific manner. Methods: From the data of 1,463 patients obtained from the PARADIGM (NCT02803411) registry, we analyzed the lumen diameter st... Abstract
Journal of the American College of Cardiology, Volume 81, Issue 3, 1 1 2023, Pages e25 Reply: Outcomes in Bicuspid Aortic Valve Disease. Hecht S, Bax JJ, Pibarot P
Cited 11 times since 2023 (8 per year) source: EuropePMC
European heart journal, Volume 44, Issue 1, 1 1 2023, Pages 28-40 Valvular heart disease: shifting the focus to the myocardium. Ajmone Marsan N, Delgado V, Shah DJ, Pellikka P, Bax JJ, Treibel T, Cavalcante JL
Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative valvular heart disease (VHD). However, to give an indication for valvular intervention, current guidelines include parameters of cardiac chamber dilatation or function which are subject to variability, do not directly reflect myocardial structural changes, and, more importantly, seem to be not sensitive enough in depicting early signs of myocardial dysfunction before irreversible myocardial damage has occurr... Abstract
European heart journal, Volume 44, Issue 2, 1 1 2023, Pages 159-161 Guideline-based use of cardiac imaging for chronic coronary syndromes. van der Bijl P, Stassen J, Bax JJ
Cited 3 times since 2022 (2.2 per year) source: EuropePMC
JACC. Cardiovascular interventions, Volume 16, Issue 2, 28 4 2022, Pages 140-151 Staging Heart Failure Patients With Secondary Mitral Regurgitation Undergoing Transcatheter Edge-to-Edge Repair. Stolz L, Doldi PM, Orban M, Karam N, Puscas T, Wild MG, Popescu A, von Bardeleben RS, Iliadis C, Baldus S, Adamo M, Thiele H, Besler C, Unterhuber M, Ruf T, Pfister R, Higuchi S, Koell B, Giannini C, Petronio A, Kassar M, Weckbach LT, Butter C, Stocker TJ, Neuss M, Melica B, Braun D, Windecker S, Massberg S, Praz F, Näbauer M, Kalbacher D, Lurz P, Metra M, Bax JJ, Hausleiter J, EuroSMR Investigators
Background: Secondary mitral regurgitation (SMR) is a progressive disease with characteristic pathophysiological changes that may influence prognosis. Although the staging of SMR patients suffering from heart failure with reduced ejection fraction (HFrEF) according to extramitral cardiac involvement has prognostic value in medically treated patients, such data are so far lacking for edge-to-edge mitral valve repair (M-TEER). Objectives: This study sought to classify M-TEER patients into disease... Abstract
Circulation, Volume 147, Issue 10, 27 4 2022, Pages 798-811 The MIDA-Q Mortality Risk Score: A Quantitative Prognostic Tool for the Mitral Valve Prolapse Spectrum. Essayagh B, Benfari G, Antoine C, Grigioni F, Le Tourneau T, Roussel JC, Bax JJ, Delgado V, Ajmone Marsan N, van Wijngaarden A, Tribouilloy C, Rusinaru D, Hochstadt A, Topilsky Y, Thapa P, Michelena HI, Enriquez-Sarano M
Background: Mitral valve prolapse (MVP) is responsible for a considerable disease burden but is widely heterogeneous. The lack of a comprehensive prognostic instrument covering the entire MVP spectrum, encompassing the quantified consequent degenerative mitral regurgitation (DMR), hinders clinical management and therapeutic trials. Methods: The new Mitral Regurgitation International Database Quantitative (MIDA-Q) registry enrolled 8187 consecutive patients (ages 63±16 years, 47% women, follow-up... Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 30, Issue 4, 24 4 2022, Pages 1396-1398 More evidence for prognostic value of quantification of myocardial perfusion. Saraste A, Knuuti J, Bax JJ
The American journal of cardiology, Volume 190, 20 3 2022, Pages 41-47 Association Between Chronic Obstructive Pulmonary Disease and All-Cause Mortality After Aortic Valve Replacement for Aortic Stenosis. Myagmardorj R, Nabeta T, Hirasawa K, Singh GK, van der Kley F, de Weger A, Ajmone Marsan N, Bax JJ, Delgado V
Chronic obstructive pulmonary disease (COPD) and aortic stenosis (AS) are the most common diseases in which age plays a major role in the increase of their prevalence and when they co-exist, the outcomes prognosis worsens significantly. The aim of the present study was to evaluate the association between pulmonary functional parameters and all-cause mortality after aortic valve replacement (transcatheter or surgical). A total of 400 patients with severe AS and preoperative pulmonary functional t... Abstract
Cited 1 times since 2022 (0.7 per year) source: EuropePMC
Journal of the American Heart Association, Volume 11, Issue 24, 19 3 2022, Pages e027260 Performance of the American Heart Association/American College of Cardiology Guideline-Recommended Pretest Probability Model for the Diagnosis of Obstructive Coronary Artery Disease. Winther S, Murphy T, Schmidt SE, Bax JJ, Wijns W, Knuuti J, Bøttcher M
Background Substantial differences exist between different guideline-recommended pretest probability (PTP) models for the detection of obstructive coronary artery disease (CAD). This study was performed to study the performance of the 2021 American Heart Association/American College of Cardiology (AHA/ACC) guideline-recommended PTP (AHA/ACC-PTP) model in assessing the likelihood of obstructive CAD compared with previously proposed models. Methods and Results Symptomatic patients (N=50 561) refer... Abstract
Cited 1 times since 2022 (0.7 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 16, Issue 4, 14 2 2022, Pages 495-504 Clinical and Coronary Plaque Predictors of Atherosclerotic Nonresponse to Statin Therapy. van Rosendael SE, van den Hoogen IJ, Lin FY, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Leipsic JA, Maffei E, Pontone G, Raff GL, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Lee SE, Virmani R, Samady H, Stone PH, Min JK, Narula J, Shaw LJ, Chang HJ, van Rosendael AR, Bax JJ
Background: Statins reduce the incidence of major cardiovascular events, but residual risk remains. The study examined the determinants of atherosclerotic statin nonresponse. Objectives: This study aimed to investigate factors associated with statin nonresponse-defined atherosclerosis progression in patients treated with statins. Methods: The multicenter PARADIGM (Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging) registry included patients who underwen... Abstract
Cited 5 times since 2022 (3.5 per year) source: EuropePMC
The American journal of medicine, Volume 136, Issue 3, 10 2 2022, Pages 260-269.e7 Integrating Coronary Atherosclerosis Burden and Progression with Coronary Artery Disease Risk Factors to Guide Therapeutic Decision Making. Freeman AM, Raman SV, Aggarwal M, Maron DJ, Bhatt DL, Parwani P, Osborne J, Earls JP, Min JK, Bax JJ, Shapiro MD
Importance: Although atherosclerosis represents the primary driver of coronary artery disease, evaluation and treatment approaches have historically relied upon indirect markers of atherosclerosis that include surrogates (cholesterol), signs (angina), and sequelae (ischemia) of atherosclerosis. Direct quantification and characterization of atherosclerosis may encourage a precision heart care paradigm that improves diagnosis, risk stratification, therapeutic decision-making, and longitudinal dise... Abstract
Frontiers in cardiovascular medicine, Volume 9, 6 1 2022, Pages 1053100 Editorial: Atherosclerosis and functional imaging. Huang JY, Lin YH, Hung CL, Chen WP, Tamaki N, Bax JJ, Morris DA, Korosoglou G, Wu YW
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 30, Issue 1, 6 1 2022, Pages 10-13 Third decade of the Journal of Nuclear Cardiology: reflections of an author, reviewer, and editor. Bax JJ
European heart journal. Cardiovascular Imaging, Volume 24, Issue 1, 1 1 2022, Pages 36-37 Coronary artery calcium scoring in the general population. van der Bijl P, Kuneman J, Bax JJ
Cited 6 times since 2022 (4.1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 24, Issue 1, 1 1 2022, Pages 142-151 Prognostic value of left atrial reservoir function in patients with severe primary mitral regurgitation undergoing mitral valve repair. Stassen J, van Wijngaarden AL, Butcher SC, Palmen M, Herbots L, Bax JJ, Delgado V, Ajmone Marsan N
Aims: Mitral regurgitation (MR) has a significant haemodynamic impact on the left atrium. Assessment of left atrial reservoir strain (LARS) may have important prognostic implications, incremental to left atrial (LA) volume, and conventional parameters of left ventricular (LV) structure and function. This study investigated whether preoperative assessment of LARS by speckle tracking echocardiography is associated with long-term outcomes in patients undergoing mitral valve repair for severe primar... Abstract
Cited 1 times since 2022 (0.7 per year) source: EuropePMC
International journal of cardiology, Volume 373, 23 4 2022, Pages 101-106 Incremental value of left ventricular global longitudinal strain in moderate aortic stenosis and reduced left ventricular ejection fraction. Stassen J, Singh GK, Pio SM, Chimed S, Butcher SC, Hirasawa K, Marsan NA, Bax JJ
Background: Moderate aortic stenosis (AS) often coexists with left ventricular (LV) systolic dysfunction and may affect survival through afterload mismatch. Because outcomes are ultimately driven by the condition of the LV, accurate assessment of LV performance is crucial to improve risk stratification. This study investigated the prognostic value of LV global longitudinal strain (GLS) in patients with moderate AS and reduced LV systolic dysfunction. Methods: Patients with moderate AS (aortic va... Abstract