Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
884 results
Cited 1 times since 2020 (0.3 per year) source: EuropePMC
Clinical case reports, Volume 8, Issue 11, 6 1 2020, Pages 2320-2321 The constrictive consequences of pericardial calcifications. Egorova AD, Schalij MJ, Kiès P
A 53-year-old man presented with symptomatic severe pulmonary valve regurgitation. He underwent a diagnostic catheterization. A heavily calcified pericardium and the pressure tracings illustrate typical features of constrictive pericarditis physiology, including the "square root sign." This condition is important to recognize given the progressive nature and poor prognosis if untreated. Abstract
Cited 8 times since 2020 (2.1 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 6, Issue 9, 29 5 2020, Pages 1103-1114 Prevalence and Prognostic Impact of Pathogenic Variants in Patients With Dilated Cardiomyopathy Referred for Ventricular Tachycardia Ablation. Ebert M, Wijnmaalen AP, de Riva M, Trines SA, Androulakis AFA, Glashan CA, Schalij MJ, Peter van Tintelen J, Jongbloed JDH, Zeppenfeld K
Objectives: This study aimed to assess the frequency of (likely) pathogenic variants (LP/Pv) among dilated cardiomyopathy (DCM) ventricular tachycardia (VT) patients referred for CA and their impact on procedural outcome and long-term prognosis. Background: The prevalence of genetic variants associated with monomorphic VT among DCM is unknown. Methods: Ninety-eight consecutive patients (age 56 ± 15 years; 84% men, left ventricular ejection fraction [LVEF] 39 ± 12%) referred for DCM-VT ablation w... Abstract
Cited 10 times since 2020 (2.6 per year) source: EuropePMC
JMIR human factors, Volume 7, Issue 2, 23 4 2020, Pages e17147 Perspectives of Patients and Professionals on Information and Education After Myocardial Infarction With Insight for Mixed Reality Implementation: Cross-Sectional Interview Study. Hilt AD, Mamaqi Kapllani K, Hierck BP, Kemp AC, Albayrak A, Melles M, Schalij MJ, Scherptong RWC
Background: Patient education is crucial in the secondary prevention of cardiovascular disease. Novel technologies such as augmented reality or mixed reality expand the possibilities for providing visual support in this process. Mixed reality creates interactive digital three-dimensional (3D) projections overlaying virtual objects on the real-world environment. While augmented reality only overlays objects, mixed reality not just overlays but anchors virtual objects to the real world. However, r... Abstract
Cited 1 times since 2020 (0.2 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 33, Issue 8, 4 1 2020, Pages 964-972 Correlates and Long-Term Implications of Left Ventricular Mechanical Dispersion by Two-Dimensional Speckle-Tracking Echocardiography in Patients with ST-Segment Elevation Myocardial Infarction. Abou R, Goedemans L, van der Bijl P, Fortuni F, Prihadi EA, Mertens B, Schalij MJ, Ajmone Marsan N, Bax JJ, Delgado V
Background: Left ventricular (LV) mechanical dispersion (LVMD), measured with speckle-tracking echocardiography (STE) after ST-segment elevation myocardial infarction (STEMI), has been proposed as a measurement of regional heterogeneity of myocardial contraction and may reflect changes in the myocardial structure (e.g., fibrosis or edema). Further insight into this parameter may aid in the risk stratification of STEMI patients. Methods: A total of 1,000 STEMI patients (77% male, 60 ± 12 years) t... Abstract
Cited 8 times since 2020 (2 per year) source: EuropePMC
JMIR research protocols, Volume 9, Issue 4, 21 3 2020, Pages e16326 Use of Smart Technology for the Early Diagnosis of Complications After Cardiac Surgery: The Box 2.0 Study Protocol. Biersteker TE, Boogers MJ, de Lind van Wijngaarden RA, Groenwold RH, Trines SA, van Alem AP, Kirchhof CJ, van Hof N, Klautz RJ, Schalij MJ, Treskes RW
Background: Atrial fibrillation (AF), sternal wound infection, and cardiac decompensation are complications that can occur after cardiac surgery. Early detection of these complications is clinically relevant, as early treatment is associated with better clinical outcomes. Remote monitoring with the use of a smartphone (mobile health [mHealth]) might improve the early detection of complications after cardiac surgery. Objective: The primary aim of this study is to compare the detection rate of AF... Abstract
Cited 13 times since 2020 (3.2 per year) source: EuropePMC
Journal of medical genetics, Volume 57, Issue 12, 10 2 2020, Pages 843-850 Identification of known and unknown genes associated with mitral valve prolapse using an exome slice methodology. van Wijngaarden AL, Hiemstra YL, Koopmann TT, Ruivenkamp CAL, Aten E, Schalij MJ, Bax JJ, Delgado V, Barge-Schaapveld DQCM, Ajmone Marsan N
Purpose: Although a familial distribution has been documented, the genetic aetiology of mitral valve prolapse (MVP) is largely unknown, with only four genes identified so far: FLNA, DCHS1, DZIP1 and PLD1. The aim of this study was to evaluate the genetic yield in known causative genes and to identify possible novel genes associated with MVP using a heart gene panel based on exome sequencing. Methods: Patients with MVP were referred for genetic counselling when a positive family history for MVP w... Abstract
Cited 3 times since 2020 (0.7 per year) source: EuropePMC
JMIR human factors, Volume 7, Issue 2, 8 2 2020, Pages e17131 Teamwork and Safety Attitudes in Complex Aortic Surgery at a Dutch Hospital: Cross-Sectional Survey Study. Hilt AD, Kaptein AA, Schalij MJ, van Schaik J
Background: Improving teamwork in surgery is a complex goal and difficult to achieve. Human factors questionnaires, such as the Safety Attitudes Questionnaire (SAQ), can help us understand medical teamwork and may assist in achieving this goal. Objective: This paper aimed to assess local team and safety culture in a cardiovascular surgery setting to understand how purposeful teamwork improvements can be reached. Methods: Two cardiovascular surgical teams performing complex aortic treatments were... Abstract
Cited 7 times since 2020 (1.7 per year) source: EuropePMC
Journal of molecular and cellular cardiology, Volume 143, 8 2 2020, Pages 26-37 Human epicardium-derived cells reinforce cardiac sympathetic innervation. Ge Y, Smits AM, van Munsteren JC, Gittenberger-de Groot AC, Poelmann RE, van Brakel TJ, Schalij MJ, Goumans MJ, DeRuiter MC, Jongbloed MRM
Rationale: After cardiac damage, excessive neurite outgrowth (sympathetic hyperinnervation) can occur, which is related to ventricular arrhythmias/sudden cardiac death. Post-damage reactivation of epicardium causes epicardium-derived cells (EPDCs) to acquire a mesenchymal character, contributing to cardiac regeneration. Whether EPDCs also contribute to cardiac re/hyperinnervation, is unknown. Aim: To investigate whether mesenchymal EPDCs influence cardiac sympathetic innervation. Methods and res... Abstract
Cited 40 times since 2020 (9.7 per year) source: EuropePMC
JAMA network open, Volume 3, Issue 4, 1 1 2020, Pages e202165 Effect of Smartphone-Enabled Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial Infarction: A Randomized Clinical Trial. Treskes RW, van Winden LAM, van Keulen N, van der Velde ET, Beeres SLMA, Atsma DE, Schalij MJ
Importance: Smart technology via smartphone-compatible devices might improve blood pressure (BP) regulation in patients after myocardial infarction. Objectives: To investigate whether smart technology in clinical practice can improve BP regulation and to evaluate the feasibility of such an intervention. Design, setting, and participants: This study was an investigator-initiated, single-center, nonblinded, feasibility, randomized clinical trial conducted at the Department of Cardiology of the Lei... Abstract
Cited 1 times since 2020 (0.2 per year) source: EuropePMC
European journal of obstetrics, gynecology, and reproductive biology, Volume 248, 6 1 2020, Pages 150-155 Evaluation of mode of birth in pregnant women with heart disease. Petrus AHJ, Jongert BL, Kiès P, Sueters M, Jongbloed MRM, Vliegen HW, Schalij MJ, van Lith J, van den Akker T
Objective: Maternal heart disease (HD) complicates 1-4 % of pregnancies and is associated with adverse maternal and fetal outcomes. Although vaginal birth is generally recommended in the guidelines, cesarean section (CS) rates in women with HD are often high. Aim of the present study was to evaluate mode of birth and pregnancy outcomes in women with HD in a tertiary care hospital in the Netherlands. Study design: The study population consisted of 128 consecutive pregnancies in 99 women with HD,... Abstract
European heart journal. Cardiovascular Imaging, Volume 21, Issue 3, 1 1 2020, Pages 299-306 Exercise haemodynamics after restrictive mitral annuloplasty for functional mitral regurgitation. Petrus AHJ, Tops LF, Holman ER, Marsan NA, Bax JJ, Schalij MJ, Steendijk P, Klautz RJM, Braun J
Aims: Restrictive mitral annuloplasty (RMA) can provide a durable solution for functional mitral regurgitation (MR), but might result in obstruction to antegrade mitral flow. Aim of this study was to assess the magnitude of change in mitral valve area (MVA) during exercise after RMA, to relate the change in MVA to left ventricular (LV) geometry and function, and to assess its haemodynamic and clinical impact. Methods and results: Bicycle exercise echocardiography was performed in 32 patients aft... Abstract
Cited 13 times since 2020 (3.1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 21, Issue 3, 1 1 2020, Pages 273-281 The impact of visceral and general obesity on vascular and left ventricular function and geometry: a cross-sectional magnetic resonance imaging study of the UK Biobank. van Hout MJP, Dekkers IA, Westenberg JJM, Schalij MJ, Scholte AJHA, Lamb HJ
Aims: We aimed to evaluate the associations of body fat distribution with cardiovascular function and geometry in the middle-aged general population. Methods and results: Four thousand five hundred and ninety participants of the UK Biobank (54% female, mean age 61.1 ± 7.2 years) underwent cardiac magnetic resonance for assessment of left ventricular (LV) parameters [end-diastolic volume (EDV), ejection fraction (EF), cardiac output (CO), and index (CI)] and magnetic resonance imaging for body co... Abstract
Cited 11 times since 2020 (2.6 per year) source: EuropePMC
International journal of cardiology, Volume 306, 17 3 2020, Pages 78-85 Coronary anomalies in tetralogy of Fallot - A meta-analysis. Koppel CJ, Jongbloed MRM, Kiès P, Hazekamp MG, Mertens BJA, Schalij MJ, Vliegen HW
Background: An anomalous coronary artery is reported in 2% to 23% of patients with tetralogy of Fallot (TOF). Knowledge of coronary anatomy prior to corrective surgery is vital to avoid damage to vessels crossing the right ventricular outflow tract (RVOT). A meta-analysis on the prevalence of anomalous coronary arteries in TOF is lacking to date. Here, an overview of coronary anomalies in TOF is provided and implications for patient management are discussed. Methods: PubMed, Embase and Web of Sc... Abstract
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
Philosophy, ethics, and humanities in medicine : PEHM, Volume 15, Issue 1, 13 2 2020, Pages 2 Heart in art: cardiovascular diseases in novels, films, and paintings. Kaptein AA, van der Meer PB, Florijn BW, Hilt AD, Murray M, Schalij MJ
Background: Understanding representations of disease in various art genres provides insights into how patients and health care providers view the diseases. It can also be used to enhance patient care and stimulate patient self-management. Methods: This paper reviews how cardiovascular diseases are represented in novels, films, and paintings: myocardial infarction, aneurysm, hypertension, stroke, heart transplantation, Marfan's disease, congestive heart failure. Various search systems and de... Abstract
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
Journal of applied physiology (Bethesda, Md. : 1985), Volume 128, Issue 3, 30 5 2020, Pages 545-553 The proarrhythmic features of pathological cardiac hypertrophy in neonatal rat ventricular cardiomyocyte cultures. Neshati Z, Schalij MJ, de Vries AAF
Different factors may trigger arrhythmias in diseased hearts, including fibrosis, cardiomyocyte hypertrophy, hypoxia, and inflammation. This makes it difficult to establish the relative contribution of each of them to the occurrence of arrhythmias. Accordingly, in this study, we used an in vitro model of pathological cardiac hypertrophy (PCH) to investigate its proarrhythmic features and the underlying mechanisms independent of fibrosis or other PCH-related processes. Neonatal rat ventricular ca... Abstract
Cited 7 times since 2019 (1.6 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 27, Issue 12, 1 1 2019, Pages 590-593 Ventricular assist device implantation in patients with a failing systemic right ventricle: a call to expand current practice. Zandstra TE, Palmen M, Hazekamp MG, Meyns B, Beeres SLMA, Holman ER, Kiès P, Jongbloed MRM, Vliegen HW, Egorova AD, Schalij MJ, Tops LF
Ventricular assist device (VAD) implantation is an established treatment modality for patients with end-stage heart failure, and improves symptoms and survival. In the Netherlands, it is not yet routinely considered in patients with congenital heart disease and failing systemic right ventricle (SRV). Recently, a VAD was implanted in 2 SRV patients, one who underwent a Mustard procedure during infancy for transposition of the great arteries (male, 47 years old) and one with a congenitally correct... Abstract
Journal of cardiothoracic surgery, Volume 14, Issue 1, 21 3 2019, Pages 200 Vasoresponsiveness in patients with heart failure (VASOR): protocol for a prospective observational study. van Vessem ME, Beeres SLMA, de Wilde RBP, de Vries R, Berendsen RR, de Jonge E, Danser AHJ, Klautz RJM, Schalij MJ, Palmen M
Background: Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of vasodilator pathways, inactivation of vasoconstrictor pathways and the resistance to vasopressors. However, the precise etiology remains unclear. The aim of the Vasoresponsiveness in patients with heart failure (VASOR) study is to objectify and characterize the altered vasoresponsiveness in patients with heart failure, before, during... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, Volume 25, Issue 3, 10 2 2019, Pages e12722 An initial exploration of subtraction electrocardiography to detect myocardial ischemia in the prehospital setting. Ter Haar CC, Peters RJG, Bosch J, Sbrollini A, Gripenstedt S, Adams R, Bleijenberg E, Kirchhof CJHJ, Alizadeh Dehnavi R, Burattini L, de Winter RJ, Macfarlane PW, Postema PG, Man S, Scherptong RWC, Schalij MJ, Maan AC, Swenne CA
Background: In the prehospital triage of patients presenting with symptoms suggestive of acute myocardial ischemia, reliable myocardial ischemia detection in the electrocardiogram (ECG) is pivotal. Due to large interindividual variability and overlap between ischemic and nonischemic ECG-patterns, incorporation of a previous elective (reference) ECG may improve accuracy. The aim of the current study was to explore the potential value of serial ECG analysis using subtraction electrocardiography. M... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 27, Issue 11, 1 1 2019, Pages 550-558 Myocardial infarction patients referred to the primary care physician after 1‑year treatment according to a guideline-based protocol have a good prognosis. Bodde MC, van Hattem NE, Abou R, Mertens BJA, van Duijn HJ, Numans ME, Bax JJ, Schalij MJ, Jukema JW
Introduction: Identifying ST-elevation myocardial infarction (STEMI) patients who can be referred back to the general practitioner (GP) can improve patient-tailored care. However, the long-term prognosis of patients who are returned to the care of their GP is unknown. Therefore, the aim of this study was to assess the long-term prognosis of patients referred back to the GP after treatment in accordance with a 1-year institutional guideline-based protocol. Methods: All consecutive patients treate... Abstract
Cited 8 times since 2019 (1.8 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 11, 1 1 2019, Pages 1231-1238 Referral of patients for fractional flow reserve using quantitative flow ratio. Smit JM, Koning G, van Rosendael AR, El Mahdiui M, Mertens BJ, Schalij MJ, Jukema JW, Delgado V, Reiber JHC, Bax JJ, Scholte AJ
Aims: Quantitative flow ratio (QFR) is a recently developed technique to calculate fractional flow reserve (FFR) based on 3D quantitative coronary angiography and computational fluid dynamics, obviating the need for a pressure-wire and hyperaemia induction. QFR might be used to guide patient selection for FFR and subsequent percutaneous coronary intervention (PCI) referral in hospitals not capable to perform FFR and PCI. We aimed to investigate the feasibility to use QFR to appropriately select... Abstract