Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7496 results
Cited 462 times since 1994 (15.5 per year) source: EuropePMC
American journal of respiratory cell and molecular biology, Volume 11, Issue 1, 1 1 1994, Pages 95-102 Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol. Stolk J, Hiltermann TJ, Dijkman JH, Verhoeven AJ
Phagocytes are able to generate reactive oxygen species by an activatable NADPH oxidase system. We investigated the inhibition of NADPH oxidase activation by a methoxy-substituted catechol, apocynin. Oxygen uptake by neutrophils incubated with 300 microM apocynin was completely inhibited at 7 min after addition of serum-treated zymosan (STZ), with a lagtime of inhibition of 2 to 3 min. The lagtime of effect of apocynin in neutrophils relatively deficient of myeloperoxidase was about 50% longer w... Abstract
Cited 8 times since 1994 (0.3 per year) source: EuropePMC
Laboratory investigation; a journal of technical methods and pathology, Volume 71, Issue 1, 1 1 1994, Pages 61-66 Quantitation of DNA topoisomerase II alpha messenger ribonucleic acid levels in a small cell lung cancer cell line and two drug resistant sublines using a polymerase chain reaction-aided transcript titration assay. Withoff S, Smit EF, Meersma GJ, van den Berg A, Timmer-Bosscha H, Kok K, Postmus PE, Mulder NH, de Vries EG, Buys CH
Background: We have modified a polymerase chain reaction (PCR)-aided transcript titration assay (1) in order to allow quantitation of low amounts of DNA topoisomerase II alpha mRNA in small RNA samples. Experimental design: The titration assay was used to quantitate the amount of DNA topoisomerase II alpha mRNA in a human small cell lung carcinoma cell line, GLC4 and its drug-resistant sublines, GLC4/ADR and GLC4/CDDP. These cell lines show differences in DNA topoisomerase II alpha protein level... Abstract
Cited 12 times since 1994 (0.4 per year) source: EuropePMC
The European respiratory journal, Volume 7, Issue 7, 1 1 1994, Pages 1281-1284 Treatment of patients with spontaneous pneumothorax during videothoracoscopy. Janssen JP, van Mourik J, Cuesta Valentin M, Sutedja G, Gigengack K, Postmus PE
Thoracoscopy for spontaneous pneumothorax has been performed over the years by many pulmonologists. The aim of the procedure was merely diagnostic: the detection of blebs and bullae. Therapeutic modalities were restricted to chemical pleurodesis. The development of videothoracoscopy has made more complex interventions, such as bullectomy possible. A protocol for videothoracoscopic treatment of spontaneous pneumothorax, with all treatment modalities in one session, has been developed. All patient... Abstract
Chest, Volume 106, Issue 1, 1 1 1994, Pages 265-267 Pneumonia after aspiration of grit. Zweegman S, Koeleman HG, van Kralingen KW, Postmus PE
Cited 1 times since 1994 (0 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 138, Issue 30, 1 1 1994, Pages 1529-1531 [Bacteremia caused by Streptococcus salivarius and S. Milleri, and colonic carcinoma]. Smit EF, Wijnja L, Manson WL
There is a well-known association between colon carcinoma and bacteraemia with Streptococcus bovis biotype I. There are also associations, less well known, with other streptococci of the viridans group. In three patients, a man of 44, a woman of 53 and one of 52 years old, colorectal carcinomas were diagnosed in association with bacteraemia with S. salivarius, S. milleri, and S. salivarius respectively. Abstract
Cited 1 times since 1994 (0 per year) source: EuropePMC
The European respiratory journal, Volume 7, Issue 7, 1 1 1994, Pages 1379-1380 Skin lesions and an intrathoracic mass. Vasmel WL, van Mourik JC, Jiwa MN, Postmus PE
We describe a case of thoracic actinomycosis in a previously healthy man. The clinical features were a paramediastinal mass with skin lesions due to haematogenic dissemination. After parasternal mediastomy, the diagnosis was made. After treatment with penicillin, there was complete recovery. Abstract
Cited 30 times since 1994 (1 per year) source: EuropePMC
Lung cancer (Amsterdam, Netherlands), Volume 11, Issue 1-2, 1 1 1994, Pages 1-17 Bronchoscopic treatment of lung tumors. Sutedja G, Postmus PE
Several bronchoscopic techniques for the treatment of patients with tracheobronchial pathology have become available during the last decade. Technical development and additional instruments have provided the bronchoscopist with several alternatives for bronchoscopic therapeutic interventions. The majority of patients with malignant tracheobronchial neoplasm have a dismal prognosis. Palliation is the main aim of the treatment. However, in patients with an early-stage tumor, bronchoscopic treatmen... Abstract
Cited 18 times since 1994 (0.6 per year) source: EuropePMC
Electroencephalography and clinical neurophysiology, Volume 93, Issue 3, 1 1 1994, Pages 163-168 Fasciculation potentials in foot and leg muscles of healthy young adults. Van der Heijden A, Spaans F, Reulen J
The occurrence of fasciculation potentials (FPs) was studied in healthy subjects aged 18-25. In 25 males and 25 females 3 intrinsic foot muscles, the tibialis anterior and the gastrocnemius muscles on both sides were monitored with surface electrodes for 2 min periods. Only potentials with a peak-to-peak amplitude of at least 50 microV were counted. The number of FPs per minute (FPs/min) was significantly higher in the abductor hallucis (AH) and significantly lower in the tibialis anterior as co... Abstract
Cited 34 times since 1994 (1.1 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 107, Issue 6, 1 1 1994, Pages 1416-1422 Inhibition of the fetal stress response improves cardiac output and gas exchange after fetal cardiac bypass. Fenton KN, Heinemann MK, Hickey PR, Klautz RJ, Liddicoat JR, Hanley FL
Cardiac bypass in late-gestation fetal lambs causes severe placental vasoconstriction, which leads to fetal death from hypoxemia and respiratory acidosis. This response can be blocked by the administration of indomethacin; however, a fatal metabolic acidosis then gradually develops in the fetus. Because the fetus is known to mount an intensive catecholamine response to stress, and because the fetal myocardium is particularly sensitive to increased afterload, we hypothesized that elevated afterlo... Abstract
Cited 11 times since 1994 (0.4 per year) source: EuropePMC
Journal of molecular and cellular cardiology, Volume 26, Issue 5, 1 1 1994, Pages 639-648 The effect of sarcolemmal cholesterol content on the tolerance to anoxia in cardiomyocyte cultures. Bastiaanse EM, van der Valk-Kokshoorn LJ, Egas-Kenniphaas JM, Atsma DE, van der Laarse A
To determine whether the sarcolemmal-free cholesterol content influences the tolerance to anoxia in cultured neonatal rat cardiomyocytes, we modulated the free cholesterol content of the cultures, and determined the time course of anoxia-induced cell death. Incubation for 5 h with liposomes having a free cholesterol to phospholipid molar ratio of 2, 0.5 and 0, resulted in a change of cellular free cholesterol content by +54.7 +/- 5.8% (P < 0.001), by -5.2 +/- 6.3% (n.s.), and by -22.1 +/- 4.9... Abstract
Cited 14 times since 1994 (0.5 per year) source: EuropePMC
Journal of vascular research, Volume 31, Issue 3, 1 1 1994, Pages 153-162 In the normal rabbit femoral artery increasing arterial wall injury does not lead to increased intimal hyperplasia. van Erven L, Post MJ, Velema E, Borst C
Angioplasty inflicts damage to the arterial wall. We studied whether augmented medial smooth muscle cell necrosis leads to augmented intimal hyperplasia and thus aggravates restenosis. Sixty-three normal femoral arteries of New Zealand White rabbits were overstretched with an angioplasty balloon during either maximal vasoconstriction with phenylephrine (32 arteries) or maximal vasodilation with nitroprusside (31 arteries). After 3 days' survival, medial necrosis was determined as percentage... Abstract
Cited 78 times since 1994 (2.6 per year) source: EuropePMC
The American journal of physiology, Volume 266, Issue 4 Pt 2, 1 1 1994, Pages H1565-71 Heart rate and heart rate variability as indexes of sympathovagal balance. Bootsma M, Swenne CA, Van Bolhuis HH, Chang PC, Cats VM, Bruschke AV
According to the Rosenblueth-Simeone model, the heart rate (HR) is proportional to the sympathovagal balance. The individual proportionality constant is the intrinsic heart rate, which can only be determined invasively. The normalized low-frequency heart rate variability power (LF) has been raised as a calibrated noninvasive alternative. To concrete this assumption, we studied the individual LF-HR relation during incremental head-up tilt (0, 10, 20, 30, 40, 45, 50, 55, 60, 65, 70, 75, and 80 deg... Abstract
Cited 17 times since 1994 (0.6 per year) source: EuropePMC
Pharmacological research, Volume 29, Issue 3, 1 1 1994, Pages 261-272 Endothelial dysfunction and dyslipidemia: possible effects of lipid lowering and lipid modifying therapy. van Boven AJ, Jukema JW, Paoletti R
Hypercholesterolemic and atherosclerotic coronary endothelial dysfunction consist of a progressive, not irreversible, impairment in reactions to various endothelium dependent relaxing substances in both the epicardial coronary artery and in the resistance vessel. Paradoxical vasoconstriction, dynamic stenoses and dysregulation of the coronary blood flow make this endothelial dysfunction contribute to the pathogenesis of myocardial ischemia. The selectivity of the impairment makes the concept of... Abstract
Cited 10 times since 1994 (0.3 per year) source: EuropePMC
FEBS letters, Volume 343, Issue 2, 1 1 1994, Pages 151-154 Simvastatin-sodium delays cell death of anoxic cardiomyocytes by inhibition of the Na+/Ca2+ exchanger. Bastiaanse EM, Atsma DE, Kuijpers MM, Van der Laarse A
When incubated under anoxic conditions, cultured neonatal cardiomyocytes undergo cell necrosis. Simvastatin-sodium, the bioactive metabolite of simvastatin (a potent serum cholesterol-lowering drug), delayed the anoxia-induced myocyte necrosis in a dose-dependent manner. This beneficial effect of simvastatin-sodium could not be attributed to its cholesterol-lowering properties. We found that simvastatin-sodium, at concentrations of 20 and 50 microM, attenuated the rise in intracellular Ca2+ conc... Abstract
Cited 74 times since 1994 (2.5 per year) source: EuropePMC
Pediatric research, Volume 35, Issue 3, 1 1 1994, Pages 329-333 Relationship between brain blood flow and carotid arterial flow in the sheep fetus. van Bel F, Roman C, Klautz RJ, Teitel DF, Rudolph AM
The present study investigates whether changes in total brain blood flow can be reliably estimated by changes in carotid arterial blood flow in fetal and perinatal lambs. We therefore compared carotid arterial blood flow, measured with implanted transit-time ultrasound transducers, with brain blood flow, measured by radioactive microspheres in fetal lambs during normal oxygenation and during pulmonary ventilation with oxygen, with PO2 ranging from levels normal for the healthy fetus to levels no... Abstract
Cited 2 times since 1994 (0.1 per year) source: EuropePMC
Thorax, Volume 49, Issue 3, 1 1 1994, Pages 289-290 Photodynamic therapy for treatment of bronchial carcinomas. Sutedja G, Risse R, Van Mourik JC, Postmus PE
Cited 4 times since 1994 (0.1 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 138, Issue 13, 1 1 1994, Pages 661-664 [Treatment of spontaneous pneumothorax: survey among Dutch pneumonologists]. Janssen JP, Cuesta MA, Postmus PE
Objective: To gain insight into the treatment of spontaneous pneumothorax in the Netherlands. Design: Questionnaire. Setting: Nationwide in the Netherlands. Method: A questionnaire was sent to all 286 practising pulmonologists in the Netherlands to inquire about the mode of treatment used for spontaneous pneumothorax. Answers were sorted by size of practice. University hospital, non-university hospitals qualified for residency training and offices with at least 4 pulmonologists were classified a... Abstract
Cited 1 times since 1994 (0 per year) source: EuropePMC
The Netherlands journal of medicine, Volume 44, Issue 2, 1 1 1994, Pages 60-64 Q-fever in a patient with a ventriculo-peritoneal drain. Case report and short review of the literature. Lohuis PJ, Ligtenberg PC, Diepersloot RJ, de Graaf M
Although Q-fever is still a relatively rare disease in the Netherlands, its incidence seems to be increasing. In this article we describe the case-history of a 65-year-old woman with a Pudenz-drain, who acquired Q-fever pneumonia while manuring her garden. The course of the disease was deviant, which most likely was caused by colonization of the ventriculo-peritoneal drain with Coxiella burnetii. Q-fever usually presents as a self-limiting illness. In the case of chronic Q-fever, complications s... Abstract
Cited 1 times since 1994 (0 per year) source: EuropePMC
The European respiratory journal, Volume 7, Issue 2, 1 1 1994, Pages 419-420 Haemoptysis and an abnormal X-ray after prolonged treatment in the ICU. van Kralingen KW, Hekker TA, Bril H, Strack van Schijndel RJ, Postmus PE
We describe a case of Nocardia bronchopneumonia occurring in a patient after 5 weeks of treatment in an ICU. The clinical features were haemoptysis and fever, and an aspecific coarse nodular pattern on the chest roentgenogram. The diagnosis was made, after death, by positive blood cultures for Nocardia asteroides and autopsy showing Nocardia bronchopneumonia. Abstract
Cited 17 times since 1994 (0.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 23, Issue 2, 1 1 1994, Pages 514-524 Nonlinearity of the left ventricular end-systolic wall stress-velocity of fiber shortening relation in young pigs: a potential pitfall in its use as a single-beat index of contractility. Banerjee A, Brook MM, Klautz RJ, Teitel DF
Objectives: We sought to evaluate in the young heart the primary assumptions on which the current use of the mean "velocity of fiber shortening corrected for heart rate" as a noninvasive index of contractility are based. Background: End-systolic wall stress-velocity of fiber shortening relation has been applied as a single-beat, load-independent index of contractility in children. This use is based on poorly validated assumptions of linearity, parallel shifts with changing contractile... Abstract