Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7487 results
Cited 9 times since 2001 (0.4 per year) source: EuropePMC
Nuclear medicine communications, Volume 22, Issue 1, 1 1 2001, Pages 45-55 The additive value of gated SPET myocardial perfusion imaging in patients with known and suspected coronary artery disease. Bavelaar-Croon CD, Atsma DE, van der Wall EE, Dibbets-Schneider P, Zwinderman AH, Pauwels EK
In myocardial perfusion scintigraphy, the clinical significance of fixed defects presents some difficulty. In this study, we evaluated whether additional information on left ventricular function assessed by quantitative gated single-photon emission computed tomography (gated SPET) would increase the diagnostic yield of the study in such patients. We studied 55 patients with a previous myocardial infarction and 20 patients without a previous myocardial infarction using gated SPET 99Tc(m)-tetrofos... Abstract
Cited 17 times since 2001 (0.7 per year) source: EuropePMC
Journal of biomechanics, Volume 34, Issue 1, 1 1 2001, Pages 41-50 Predicting systolic and diastolic aortic blood pressure and stroke volume in the intact sheep. Segers P, Steendijk P, Stergiopulos N, Westerhof N
We developed a mathematical model describing the interaction between the heart and the arterial system. The model was constructed and tested on basis of invasive hemodynamic data in six sheep. Data from a first group of three animals (49 cardiac cycles) were used to assess a template time-varying elastance curve for the left ventricle, while the baseline steady-state data of a second group of three animals were used to assess reference cardiac and arterial parameters in sheep. The model is fully... Abstract
Cited 15 times since 2001 (0.6 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 280, Issue 1, 1 1 2001, Pages H392-400 Enhanced systolic function of the right ventricle during respiratory distress syndrome in newborn lambs. De Vroomen M, Steendijk P, Lopes Cardozo RH, Brouwers HH, Van Bel F, Baan J
Respiratory distress syndrome (RDS) causes pulmonary hypertension. It is often suggested that this increased afterload for the right ventricle (RV) might lead to cardiac dysfunction. To examine this, we studied biventricular function in an experimental model. RDS was induced by lung lavages in seven newborn lambs. Five additional lambs served as controls. Cardiac function was quantified by indexes derived from end-systolic pressure-volume relations obtained by pressure-conductance catheters. Aft... Abstract
Cited 45 times since 2000 (1.9 per year) source: EuropePMC
American journal of respiratory and critical care medicine, Volume 162, Issue 6, 1 1 2000, Pages 2232-2237 Diagnosing acute pulmonary embolism: effect of chronic obstructive pulmonary disease on the performance of D-dimer testing, ventilation/perfusion scintigraphy, spiral computed tomographic angiography, and conventional angiography. ANTELOPE Study Group. Advances in New Technologies Evaluating the Localization of Pulmonary Embolism. Hartmann IJ, Hagen PJ, Melissant CF, Postmus PE, Prins MH
In patients with chronic obstructive pulmonary disease (COPD), differentiating a pulmonary embolism (PE) from an exacerbation of COPD can be difficult, since clinical signs and symptoms of the two conditions overlap. Development of reliable noninvasive or minimally invasive techniques for the diagnosis of PE is, especially in these patients, necessary. In this study we assessed the effect of COPD on the accuracy of the clinical probability estimate (CPE), spiral computed tomographic angiography... Abstract
Cited 20 times since 2000 (0.9 per year) source: EuropePMC
European journal of cancer (Oxford, England : 1990), Volume 36, Issue 18, 1 1 2000, Pages 2420-2429 Schedule-dependent pharmacodynamic effects of gemcitabine and cisplatin in mice bearing Lewis lung murine non-small cell lung tumours. van Moorsel CJ, Pinedo HM, Smid K, Comijn EM, Voorn DA, Veerman G, Lakerveld B, Van der Vijgh WJ, Giaccone G, Postmus PE, Peters GJ
The combination of 2',2'-difluorodeoxycytidine (gemcitabine, dFdC) and cis-diammine-dichloroplatinum(II) (cisplatin, CDDP) is increasingly applied in clinical oncology. We studied the underlying mechanisms of the in vivo schedule dependency and supraadditive interaction between dFdC and CDDP in C57/B16 mice bearing Lewis lung (LL) tumours. Mice were treated with CDDP (6 mg/kg) and dFdC (60 mg/kg) either simultaneously or in a 4 or 24 h interval with dFdC preceding CDDP or vice versa. F... Abstract
Cited 8 times since 2000 (0.3 per year) source: EuropePMC
Cardiovascular research, Volume 48, Issue 3, 1 1 2000, Pages 455-463 A new approach to determine parallel conductance for left ventricular volume measurements. Kornet L, Schreuder JJ, van der Velde ET, Baan J, Jansen JR
Objectives: To determine absolute ventricular volume with the conductance catheter technique, the electrical conductance of tissues and fluids (parallel conductance) around the ventricle should be determined precisely. Methods: A new objective method to estimate parallel conductance based on analysis of the dilution curve of hypertonic saline was investigated. The parallel conductances obtained with the new method (G(a)(p)) were compared to those obtained with the conventional method (G(l)(p)).... Abstract
Cited 45 times since 2000 (1.9 per year) source: EuropePMC
Critical care medicine, Volume 28, Issue 12, 1 1 2000, Pages 3891-3895 Monitoring of recruitment and derecruitment by electrical impedance tomography in a model of acute lung injury. Kunst PW, Vazquez de Anda G, Böhm SH, Faes TJ, Lachmann B, Postmus PE, de Vries PM
Objective: To evaluate a noninvasive system for obtaining information about alveolar recruitment and derecruitment in a model of acute lung injury. Design: Prospective experimental study. Setting: Animal research laboratory. Subjects: Nine anesthetized pigs. Interventions: Electrical impedance tomography measurements were performed. Electrical impedance tomography is an imaging technique that can register the ventilation-induced impedance changes in different parts of the lung. In nine anestheti... Abstract
Cited 18 times since 2000 (0.8 per year) source: EuropePMC
International journal of cardiac imaging, Volume 16, Issue 6, 1 1 2000, Pages 447-453 Good correlation between gated single photon emission computed myocardial tomography and contrast ventriculography in the assessment of global and regional left ventricular function. Atsma DE, Bavelaar-Croon CD, Germano G, Dibbets-Schneider P, van Eck-Smit BL, Pauwels EK, van der Wall EE
Purpose: The purpose of this study was to determine the reliability of the measured left ventricular ejection fraction (LVEF) and wall motion analysis by the recently introduced quantitative electrocardiographically (ECG)-gated myocardial perfusion single-photon emission computed myocardial tomography technique (gated SPECT) (QGS). Materials and methods: We compared technetium-99 m tetrofosmin gated SPECT imaging and contrast ventriculography in the assessment of global and regional left ventric... Abstract
Cited 104 times since 2000 (4.4 per year) source: EuropePMC
The American journal of cardiology, Volume 86, Issue 12, 1 1 2000, Pages 1299-1305 Comparison of gated single-photon emission computed tomography with magnetic resonance imaging for evaluation of left ventricular function in ischemic cardiomyopathy. Bax JJ, Lamb H, Dibbets P, Pelikan H, Boersma E, Viergever EP, Germano G, Vliegen HW, de Roos A, Pauwels EK, Van der Wall EE
To perform a head-to-head comparison between magnetic resonance imaging (MRI) and gated single-photon emission computed tomography (SPECT) for the evaluation of left ventricular (LV) function (LV ejection fraction [LVEF], LV volumes, and regional wall motion) in patients with ischemic cardiomyopathy, we studied 22 patients with chronic coronary artery disease and LV dysfunction. Multislice, multiphase echoplanar MRI was performed with Philips Gyroscan ACS-NT15. Image analysis was performed using... Abstract
Cited 37 times since 2000 (1.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 36, Issue 7, 1 1 2000, Pages 2104-2114 Acute and short-term effects of partial left ventriculectomy in dilated cardiomyopathy: assessment by pressure-volume loops. Schreuder JJ, Steendijk P, van der Veen FH, Alfieri O, van der Nagel T, Lorusso R, van Dantzig JM, Prenger KB, Baan J, Wellens HJ, Batista RJ
Objectives: The aim of this study was to evaluate the short-term effects of partial left ventriculectomy (PLV) on left ventricular (LV) pressure-volume (P-V) loops, wall stress, and the synchrony of LV segmental volume motions in patients with dilated cardiomyopathy. Background: Surgical LV volume reduction is under investigation as an alternative for, or bridge to, heart transplantation for patients with end-stage dilated cardiomyopathy. Methods: We measured P-V loops in eight patients with dil... Abstract
Respiratory research, Volume 1, Issue 3, 6 1 2000, Pages 178-179 World Congress on Lung Health and 10th ERS Annual Congress 30 August-3 September 2000, Florence, Italy. Hiemstra PS
Cited 37 times since 2000 (1.6 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 11, Issue 11, 1 1 2000, Pages 1183-1192 Three-dimensional catheter positioning during radiofrequency ablation in patients: first application of a real-time position management system. de Groot NM, Bootsma M, van der Velde ET, Schalij MJ
Introduction: Precise localization of target sites for radiofrequency catheter ablation (RFCA) of arrhythmias is hampered by the relative inaccuracy of X-ray localization procedures. This study evaluated the efficacy of a three-dimensional (3D) real-time position management system in guiding RFCA procedures in patients. Methods and results: Patients (n = 30, age 59+/-20 years) referred for ablation of either atrial flutter (n = 10), ventricular tachycardia (n = 15), or accessory pathways (n = 5)... Abstract
Cited 1 times since 2000 (0 per year) source: EuropePMC
Health & social work, Volume 25, Issue 4, 1 1 2000, Pages 276-279 Suggestions to social workers for surviving in managed care. Schneider AW, Hyer K, Luptak M
Cited 75 times since 2000 (3.2 per year) source: EuropePMC
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 18, Issue 21, 1 1 2000, Pages 3722-3730 Second-line chemotherapy in relapsing or refractory non-small-cell lung cancer: a review. Huisman C, Smit EF, Giaccone G, Postmus PE
Purpose: Since the increased use of first-line chemotherapy for non-small-cell lung cancer (NSCLC), second-line chemotherapy may nowadays be considered for a growing group of patients. Guidelines for second-line treatment have to be developed yet. Methods: We reviewed the published literature on second-line chemotherapy for NSCLC with emphasis on the role of factors such as pretreatment, response to first-line treatment, and length of disease-free-interval. Results: Thirty-four single-agent-stud... Abstract
Cited 102 times since 2000 (4.3 per year) source: EuropePMC
Radiology, Volume 217, Issue 2, 1 1 2000, Pages 572-575 Left ventricular function: correlation of quantitative gated SPECT and MR imaging over a wide range of values. Bavelaar-Croon CD, Kayser HW, van der Wall EE, de Roos A, Dibbets-Schneider P, Pauwels EK, Germano G, Atsma DE
In 21 patients, the authors compared results with quantitative gated single photon emission computed tomography (SPECT) to results with magnetic resonance imaging in the assessment of left ventricular (LV) end-diastolic volume (LVEDV), end-systolic volume (LVESV), and ejection fraction (LVEF). Between the two methods, correlations were good for LVEF (r = 0.85), LVEDV (r = 0.94), and LVESV (r = 0.95). Quantitative gated SPECT can help determine LVEF, LVEDV, and LVESV. Abstract
Cited 28 times since 2000 (1.2 per year) source: EuropePMC
Circulation, Volume 102, Issue 21, 1 1 2000, Pages 2650-2658 Anisotropic reentry in a perfused 2-dimensional layer of rabbit ventricular myocardium. Schalij MJ, Boersma L, Huijberts M, Allessie MA
Background: Anisotropy creates nonuniformity in electrical propagation and may contribute to the occurrence of unidirectional conduction block and reentry. We describe the characteristics of reentrant tachycardia in a 2D layer of anisotropic ventricular myocardium. Methods and results: A Langendorff-perfused epicardial sheet (1.0+/-0.4 mm, n=35) was created by freezing the intramural layers of the rabbit left ventricle. Epicardial activation maps were constructed by use of different high-resolut... Abstract
Cited 29 times since 2000 (1.2 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 23, Issue 11 Pt 1, 1 1 2000, Pages 1638-1644 Reduction of radiation exposure in the cardiac electrophysiology laboratory. Wittkampf FH, Wever EF, Vos K, Geleijns J, Schalij MJ, van der Tol J, Robles de Medina EO
The purpose of this study was to determine the effects of various protective measures on patient and operator radiation dose levels in catheter ablation procedures. Catheter ablation procedures are associated with significant radiation levels. The patient's skin and operator radiation levels were measured (1) at baseline, (2) after primary beam filtration by 0.3-mm copper sheet and 2-mm aluminium plate and implementation of the LocaLisa system, and (3) after reduction of the left anterior o... Abstract
Cited 34 times since 2000 (1.4 per year) source: EuropePMC
Journal of hypertension, Volume 18, Issue 11, 1 1 2000, Pages 1635-1644 The importance of high-frequency paced breathing in spectral baroreflex sensitivity assessment. Frederiks J, Swenne CA, TenVoorde BJ, Honzíková N, Levert JV, Maan AC, Schalij MJ, Bruschke AV
Objective: Computation of the low-frequency (LF) blood pressure variability (BPV) to heart rate variability (HRV) transfer-index is a common method to assess baroreflex sensitivity (BRS), tacitly assuming that all LF-HRV is caused by baroreflex feedback of LF-BPV. However, respiration may also cause HRV by mechanisms not involving the baroreflex. Application of narrow-band (controlled) high-frequency breathing would keep such non-baroreflex-mediated HRV best out of the LF band. Spontaneous breat... Abstract
Cited 105 times since 2000 (4.5 per year) source: EuropePMC
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 18, Issue 19, 1 1 2000, Pages 3400-3408 Treatment of brain metastases of small-cell lung cancer: comparing teniposide and teniposide with whole-brain radiotherapy--a phase III study of the European Organization for the Research and Treatment of Cancer Lung Cancer Cooperative Group. Postmus PE, Haaxma-Reiche H, Smit EF, Groen HJ, Karnicka H, Lewinski T, van Meerbeeck J, Clerico M, Gregor A, Curran D, Sahmoud T, Kirkpatrick A, Giaccone G
Purpose: Approximately 60% of patients with small-cell lung cancer (SCLC) develop brain metastases. Whole-brain radiotherapy (WBRT) gives symptomatic improvement in more than 50% of these patients. Because brain metastases are a sign of systemic progression, and chemotherapy was found to be effective as well, it becomes questionable whether WBRT is the only appropriate therapy in this situation. Patients and methods: In a phase III study, SCLC patients with brain metastases were randomized to re... Abstract
Cited 1 times since 2000 (0 per year) source: EuropePMC
International journal of cardiac imaging, Volume 16, Issue 5, 1 1 2000, Pages 359-364 Stentless bioprostheses have ideal haemodynamics, even in the small aortic root. Baur LH, Houdas Y, Peels KH, Braun J, van Straten B, Prat A, Kappetein AP, Wolters-Geldoff M, van der Wall EE, Bruschke AV, Huysmans HA
Objective: To determine normal Doppler and 2D gradients and flow characteristics of the Freestyle stentless aortic bioprosthesis related to valve size. Background: The Freestyle stentless aortic bioprosthesis is one of the newer aortic xenografts. Only limited data are available of the echocardiographic flow characteristics during a mid-term follow-up period of this valve. Therefore valve performance related to valve size was measured during a follow-up period of two years. Methods: 175 consecut... Abstract