Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
481 results
The American journal of cardiology, Volume 179, 15 3 2022, Pages 64-69 Effects of Left Bundle Branch Block and Pacemaker Implantation on Left Ventricular Systolic Function After Transcatheter Aortic Valve Implantation. Dolci G, Singh GK, Wang X, van der Kley F, de Weger A, Bootsma M, Ajmone Marsan N, Bax JJ, Delgado V
Permanent pacemaker implantation (PPI) and left bundle branch block (LBBB) frequency after transcatheter aortic valve implantation (TAVI) and their effect on left ventricular ejection fraction (LVEF) remain controversial. We evaluated the incidence of PPI and new-onset LBBB after TAVI and their impact on LVEF at 6-month follow-up. Moreover, the impact of right ventricular (RV) pacing burden on changes in LVEF after TAVI was analyzed. The electrocardiograms of 377 patients (age 80 ± 7 years, 52%... Abstract
The American journal of cardiology, Volume 178, 11 2 2022, Pages 106-111 Relation of Myocardial Work Indexes and Forward Flow Reserve in Patients With Significant Secondary Mitral Regurgitation Undergoing Transcatheter Mitral Valve Repair. Yedidya I, Stassen J, Butcher SC, Pio SM, Lustosa RP, van der Bijl P, Vo NM, Namazi F, Marsan NA, Delgado V, Bax JJ
Left ventricular (LV) myocardial work (LVMW) indexes have shown incremental value over LV ejection fraction and were found to have prognostic significance in patients with secondary mitral regurgitation. We therefore aimed to investigate the association between LVMW indexes and forward flow reserve in patients with secondary mitral regurgitation, treated with transcatheter edge-to-edge repair (TEER). LVMW indexes were evaluated at baseline and forward stroke volume index (FSVI) was evaluated at... Abstract
Cited 1 times since 2022 (0.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 8, 1 1 2022, Pages 1090-1097 Association between computed tomography-derived tricuspid annular dimensions and prognosis: insights from whole-beat computed tomography assessment. Hirasawa K, Fortuni F, van Rosendael PJ, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Tricuspid regurgitation (TR) has been associated with outcome in patients treated with transcatheter aortic valve implantation (TAVI). Tricuspid annulus (TA) dimensions are associated with TR. However, the TA is highly dynamic during the cardiac cycle, and the interaction between the TA dimensions, TR, and patient prognosis has never been evaluated. This study aimed to characterize the dynamics of the TA along with the cardiac cycle and its association with prognosis in patients undergoing... Abstract
Cited 3 times since 2022 (1.7 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 62, Issue 2, 1 1 2022, Pages ezac290 Staging right heart failure in patients with tricuspid regurgitation undergoing tricuspid surgery. Galloo X, Stassen J, Butcher SC, Meucci MC, Dietz MF, Mertens BJA, Prihadi EA, van der Bijl P, Ajmone Marsan N, Braun J, Bax JJ, Delgado V
Objectives: This study evaluated the prognostic value of staging right heart failure in patients with significant tricuspid regurgitation (TR) undergoing tricuspid valve (TV) surgery. Methods: Patients with significant TR who underwent TV surgery were divided into 4 right heart failure stages according to the presence of right ventricular (RV) dysfunction and clinical signs of right heart failure: stage 1 was defined as no RV dysfunction and no signs of right heart failure; stage 2 indicated RV... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
Revista espanola de cardiologia (English ed.), Volume 76, Issue 1, 24 4 2022, Pages 2-3 Fusion imaging in congenital heart disease: just a pretty picture or a new tool to improve patient management? Regeer MV, Ajmone Marsan N
Cited 4 times since 2022 (2.2 per year) source: EuropePMC
International journal of cardiology, Volume 363, 15 3 2022, Pages 87-93 Left atrioventricular coupling index in hypertrophic cardiomyopathy and risk of new-onset atrial fibrillation. Meucci MC, Fortuni F, Galloo X, Bootsma M, Crea F, Bax JJ, Marsan NA, Delgado V
Backgrounds: This study aimed to investigate the association between left atrioventricular coupling index (LACI) and the occurrence of atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). Methods: A total of 373 patients with HCM and no history of AF were evaluated by transthoracic echocardiography. LACI was defined by the ratio of left atrial (LA) end-diastolic volume divided by left ventricular (LV) end-diastolic volume. The cut-off value for LACI (≥40%) to identify LA-... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 177, 9 2 2022, Pages 90-99 Prognostic Implications of Change in Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Implantation. Kuneman JH, Butcher SC, Singh GK, Wang X, Hirasawa K, van der Kley F, Leon MB, Knuuti J, Pibarot P, Ajmone Marsan N, Delgado V, Bax JJ
Reduced left ventricular (LV) systolic function is associated with worse prognosis in patients with severe aortic stenosis (AS) treated with transcatheter aortic valve implantation (TAVI). We aimed to examine the changes in left ventricular ejection fraction (LVEF) after TAVI among patients with varying baseline LVEF. Moreover, variables associated with lack of LVEF improvement were identified and the association with long-term outcomes was investigated. A total of 560 patients (age 80 ± 7 years... Abstract
Cited 8 times since 2022 (4.3 per year) source: EuropePMC
The American journal of cardiology, Volume 177, 9 2 2022, Pages 151-161 Right Ventricular Myocardial Work Characterization in Patients With Pulmonary Hypertension and Relation to Invasive Hemodynamic Parameters and Outcomes. Butcher SC, Feloukidis C, Kamperidis V, Yedidya I, Stassen J, Fortuni F, Vrana E, Mouratoglou SA, Boutou A, Giannakoulas G, Playford D, Ajmone Marsan N, Bax JJ, Delgado V
Noninvasive evaluation of indexes of right ventricular (RV) myocardial work (RVMW) derived from RV pressure-strain loops may provide novel insights into RV function in precapillary pulmonary hypertension. This study was designed to evaluate the association between the indexes of RVMW and invasive parameters of right heart catheterization and all-cause mortality. Noninvasive analysis of RVMW was completed in 51 patients (mean age 58.1 ± 12.7 years, 31% men) with group I or group IV pulmonary hype... Abstract
Structural heart : the journal of the Heart Team, Volume 6, Issue 3, 8 2 2022, Pages 100042 Sex-Related Differences in Medically Treated Moderate Aortic Stenosis. Stassen J, Pio SM, Ewe SH, Amanullah MR, Hirasawa K, Butcher SC, Singh GK, Sin KYK, Ding ZP, Chew NWS, Sia CH, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Background: Recent data showed poor long-term survival in patients with moderate AS. Although sex differences in left ventricular (LV) remodeling and outcome are well described in severe AS, it has not been evaluated in moderate AS. Methods: In this retrospective, multicenter study, patients with a first diagnosis of moderate AS diagnosed between 2001 and 2019 were identified. Clinical and echocardiographic parameters were recorded at baseline and compared between men and women. Patients were fo... Abstract
Cited 10 times since 2022 (5.3 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 7, 1 1 2022, Pages 885-897 The dysfunctional right ventricle: the importance of multi-modality imaging. Surkova E, Cosyns B, Gerber B, Gimelli A, La Gerche A, Ajmone Marsan N
Assessment of right ventricular (RV) function is crucial for the evaluation of the dyspnoeic patient and/or with systemic venous congestion and provides powerful prognostic insights. It can be performed using different imaging modalities including standard and advanced echocardiographic techniques, cardiac magnetic resonance imaging, computed tomography, and radionuclide techniques, which should be used in a complementary fashion. Each modality has strengths and weaknesses based on which the cho... Abstract
Cited 4 times since 2022 (2.1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 6, 1 1 2022, Pages 730-740 Clinical implications of left atrial reverse remodelling after cardiac resynchronization therapy. Stassen J, Galloo X, Chimed S, Hirasawa K, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Aims: Left atrial (LA) function is a marker of prognosis in patients with heart failure. The prognostic implications of an improvement in LA function in addition to an improvement in left ventricular (LV) function after cardiac resynchronization therapy (CRT) implantation are unknown. This study aimed to evaluate the prognostic value of a significant change in LA reservoir strain (RS) and/or LV global longitudinal strain (GLS) after initiation of CRT. Methods and results: LARS and LVGLS were mea... Abstract
Cited 4 times since 2022 (2.1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 6, 1 1 2022, Pages 781-789 Sex differences in left ventricular remodelling in patients with severe aortic valve stenosis. Kuneman JH, Singh GK, Milhorini Pio S, Hirasawa K, Hautemann D, van der Kley F, Ajmone Marsan N, Knuuti J, Delgado V, Bax JJ
Aims: Women with severe aortic stenosis (AS) have better long-term outcome after transcatheter aortic valve implantation (TAVI) but worse survival after surgical aortic valve replacement compared with men. Whether this is related to sex differences in left ventricular (LV) remodelling is unknown. The aim of this study was to examine the sex differences in LV remodelling with multidetector row computed tomography (MDCT) and outcome in patients with severe AS undergoing TAVI between 2007 and 2018.... Abstract
Cited 5 times since 2022 (2.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 6, 1 1 2022, Pages 790-799 Moderate aortic stenosis: importance of symptoms and left ventricular ejection fraction. Stassen J, Ewe SH, Butcher SC, Amanullah MR, Hirasawa K, Singh GK, Sin KYK, Ding ZP, Pio SM, Sia CH, Chew NWS, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Delgado V, Bax JJ
Aims: The aim of this study is to investigate the independent determinants of survival in patients with moderate aortic stenosis (AS), stratified by severity of symptoms and left ventricular ejection fraction (LVEF). Methods and results: Patients with a first diagnosis of moderate AS (aortic valve area >1.0 and ≤1.5 cm2) were identified. Patients were stratified by New York Heart Association (NYHA) functional class (NYHA I, NYHA II, or NYHA III-IV) and LVEF (LVEF ≥60%, LVEF 50-59%, or LVEF... Abstract
Journal of the American Heart Association, Volume 11, Issue 10, 16 3 2022, Pages e023313 Differences in Characteristics and Outcomes Between Patients With Hypertrophic Cardiomyopathy From Asian and European Centers. Tjahjadi C, Butcher SC, Zegkos T, Sia CH, Hirasawa K, Kamperidis V, Ngiam JN, Wong RCC, Efthimiadis G, Bax JJ, Delgado V, Ajmone Marsan N
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 38, Issue 9, 21 3 2022, Pages 1973-1985 Interaction between sex and left ventricular reverse remodeling and its association with outcomes after transcatheter aortic valve implantation. Kuneman JH, Butcher SC, Stassen J, Singh GK, Pio SM, van der Kley F, Ajmone Marsan N, Knuuti J, Bax JJ, Delgado V
Women with severe aortic stenosis (AS) have better long-term prognosis after transcatheter aortic valve implantation (TAVI) compared to men. Whether this is caused by sex-related differences in left ventricular (LV) reverse remodeling after TAVI is unknown. Patients with severe AS who underwent transfemoral TAVI between 2007 and 2018 were selected. LV dimensions, volumes, and ejection fraction (LVEF) were assessed by transthoracic echocardiography before TAVI and at 6 and 12 months follow-up aft... Abstract
European heart journal. Cardiovascular Imaging, Volume 23, Issue 5, 1 1 2022, Pages 590-597 EACVI survey on hypertrophic cardiomyopathy. Podlesnikar T, Cardim N, Ajmone Marsan N, D'Andrea A, Cameli M, Popescu BA, Schulz-Menger J, Stankovic I, Toplisek J, Maurer G, Haugaa KH, Dweck MR
Aims: The European Association of Cardiovascular Imaging (EACVI) Scientific Initiatives Committee performed a global survey to evaluate current practice for the assessment and management of patients with hypertrophic cardiomyopathy (HCM). Methods and results: A total of 213 centres from 38 different countries (87% European) responded to the survey. One hundred twenty-one (57%) centres followed HCM patients in a general cardiology outpatient clinic and 85 (40%) centres in a specialized HCM/cardio... Abstract
Cited 5 times since 2022 (2.4 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 5, 1 1 2022, Pages 699-707 Prognostic implications of left ventricular myocardial work index in patients with ST-segment elevation myocardial infarction and reduced left ventricular ejection fraction. Butcher SC, Lustosa RP, Abou R, Marsan NA, Bax JJ, Delgado V
Aims: This study aimed to determine whether lower values of left ventricular (LV) global work index (GWI) at baseline were associated with a reduction in LV functional recovery and poorer long-term prognosis in patients with reduced LV ejection fraction (LVEF ≤40%) following ST-segment elevation myocardial infarction (STEMI). Methods and results: A total of 197 individuals (62 ± 12 years, 75% male) with STEMI treated with primary percutaneous coronary intervention and reduced LVEF were evaluated... Abstract
Cited 5 times since 2022 (2.4 per year) source: EuropePMC
The American journal of cardiology, Volume 173, 1 1 2022, Pages 120-127 Prognostic Implications of Right Ventricular Systolic Dysfunction in Cardiac Amyloidosis. Tjahjadi C, Fortuni F, Stassen J, Debonnaire P, Lustosa RP, Marsan NA, Delgado V, Bax JJ
Left ventricular (LV) systolic dysfunction in cardiac amyloidosis (CA) is associated with poor prognosis. This study aimed to investigate the prognostic implications of right ventricular (RV) systolic dysfunction in CA. A total of 93 patients diagnosed with CA who underwent standard and speckle-tracking echocardiography were included. During a median follow-up of 17 (5 to 38) months, 42 patients (45%) died. Nonsurvivors were more likely to present with immunoglobulin light-chain amyloidosis and... Abstract
Cited 3 times since 2022 (1.4 per year) source: EuropePMC
The American journal of cardiology, Volume 172, 19 3 2022, Pages 54-61 The Quantity of Epicardial Adipose Tissue in Patients Having Ablation for Atrial Fibrillation With and Without Heart Failure. Wang X, Butcher SC, Kuneman JH, Lustosa RP, Fortuni F, Ajmone Marsan N, Knuuti J, Bax JJ, Delgado V
The distribution of epicardial adipose tissue (EAT) across the spectrum of heart failure (HF) has yet to be fully elucidated. The present study investigated the distribution of EAT in an HF spectrum and its association with clinical and echocardiographic parameters. A total of 326 patients who underwent contrast-enhanced computed tomography before transcatheter atrial fibrillation ablation with and without HF symptoms, and a wide range of left ventricular (LV) ejection fractions (LVEF) were incl... Abstract
Cited 3 times since 2022 (1.4 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 9, 17 3 2022, Pages 845359 The Prognostic Value of Right Atrial and Right Ventricular Functional Parameters in Systemic Sclerosis. Vos JL, Butcher SC, Fortuni F, Galloo X, Rodwell L, Vonk MC, Bax JJ, van Leuven SI, de Vries-Bouwstra JK, Snoeren M, El Messaoudi S, Marsan NA, Nijveldt R
Introduction: Right ventricular (RV) function is of particular importance in systemic sclerosis (SSc), since common SSc complications, such as interstitial lung disease and pulmonary hypertension may affect RV afterload. Cardiovascular magnetic resonance (CMR) is the gold standard for measuring RV function. CMR-derived RV and right atrial (RA) strain is a promising tool to detect subtle changes in RV function, and might have incremental value, however, prognostic data is lacking. Therefore, the... Abstract