Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
482 results
Cited 63 times since 2014 (6.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 100, Issue 12, 21 3 2014, Pages 960-968 Significant lead-induced tricuspid regurgitation is associated with poor prognosis at long-term follow-up. Höke U, Auger D, Thijssen J, Wolterbeek R, van der Velde ET, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: Although the presence of an RV lead is a potential cause of tricuspid regurgitation (TR), the clinical impact of significant lead-induced TR is unknown. Objective: To evaluate the effect of significant lead-induced TR on cardiac performance and long-term outcome after cardioverter-defibrillator (ICD) or pacemaker implantation. Methods: A retrospective cohort of 239 ICD (n=191) or pacemaker (n=48) recipients (age 60±14 years, 77% male) from a tertiary care university hospital, with an... Abstract
Cited 12 times since 2014 (1.2 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 27, Issue 3, 13 2 2014, Pages 239-248 Association between multilayer left ventricular rotational mechanics and the development of left ventricular remodeling after acute myocardial infarction. Abate E, Hoogslag GE, Leong DP, Bertini M, Antoni ML, Nucifora G, Joyce E, Holman ER, Siebelink HM, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Background: The identification of patients at risk for developing left ventricular (LV) remodeling after acute myocardial infarction (AMI) has crucial prognostic implications. The aims of this study were (1) to investigate the relationship between peak subepicardial and subendocardial twist and infarct transmurality, as assessed using contrast-enhanced magnetic resonance imaging, and (2) to evaluate the association between peak subepicardial and subendocardial twist and LV remodeling 6 months af... Abstract
Cited 19 times since 2013 (1.8 per year) source: EuropePMC
European heart journal, Volume 35, Issue 10, 29 5 2014, Pages 633-638 Risks and benefits of cardiac imaging: an analysis of risks related to imaging for coronary artery disease. Knuuti J, Bengel F, Bax JJ, Kaufmann PA, Le Guludec D, Perrone Filardi P, Marcassa C, Ajmone Marsan N, Achenbach S, Kitsiou A, Flotats A, Eeckhout E, Minn H, Hesse B
Cited 2 times since 2013 (0.2 per year) source: EuropePMC
The American journal of cardiology, Volume 113, Issue 6, 25 4 2013, Pages 982-987 Effect of cardiac resynchronization therapy on the sequence of mechanical activation assessed by two-dimensional radial strain imaging. Auger D, Hoke U, Thijssen J, Abate E, Yiu KH, Ewe SH, Witkowski TG, Leong DP, Holman ER, Ajmone Marsan N, Schalij MJ, Bax JJ, Delgado V
Cardiac resynchronization therapy (CRT) induces left ventricular (LV) reverse remodeling by synchronizing LV mechanical activation. We evaluated changes in segmental LV activation after CRT and related them to CRT response. A total of 292 patients with heart failure (65 ± 10 years, 77% men) treated with CRT underwent baseline echocardiographic assessment of LV volumes and ejection fraction. Time-to-peak radial strain was measured for 6 midventricular LV segments with speckle-tracking strain imag... Abstract
Cited 4 times since 2013 (0.4 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 30, Issue 2, 19 3 2013, Pages 313-322 Left ventricular twist during dobutamine stress echocardiography after acute myocardial infarction: association with reverse remodeling. Joyce E, Leong DP, Hoogslag GE, van Herck PL, Debonnaire P, Abate E, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Left ventricular (LV) twist is emerging as a marker of global LV contractility after acute myocardial infarction (AMI). This study aimed to describe stress-induced changes in LV twist during dobutamine stress echocardiography (DSE) after AMI and investigate their association with LV reverse remodeling at 6 months follow-up. In 82 consecutive first AMI patients (61 ± 12 years, 85 % male) treated with primary percutaneous coronary intervention, DSE was performed at 3 months follow-up. Two-dimensio... Abstract
Cited 33 times since 2013 (3.1 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 7, Issue 1, 1 1 2013, Pages 74-81 Association between left ventricular global longitudinal strain and adverse left ventricular dilatation after ST-segment-elevation myocardial infarction. Joyce E, Hoogslag GE, Leong DP, Debonnaire P, Katsanos S, Boden H, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Background: Myocardial infarct size is a major determinant of left ventricular (LV) remodeling after ST-segment-elevation myocardial infarction. We evaluated whether LV global longitudinal strain (GLS), proposed as a novel marker of infarct size, is associated with 3- and 6-month LV dilatation after ST-segment-elevation myocardial infarction. Methods and results: In the first ST-segment-elevation myocardial infarction patients treated with primary percutaneous coronary intervention, baseline LVG... Abstract
Cited 4 times since 2013 (0.4 per year) source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Volume 28, Issue 12, 3 1 2013, Pages 3045-3052 Echocardiographical determinants of an abnormal spatial QRS-T angle in chronic dialysis patients. de Bie MK, Ajmone Marsan N, Gaasbeek A, Bax JJ, Delgado V, Rabelink TJ, Schalij MJ, Jukema JW
Background: The spatial QRS-T angle describes the relation between ventricular depolarization and repolarization. Having a wide (abnormal) angle is considered an important predictor of arrhythmic events. Given the high incidence of sudden cardiac death in dialysis patients, this parameter is of particular interest in this patient group. The objective of this study was to assess the association of (modifiable) echocardiographic parameters and an abnormal spatial QRS-T angle in dialysis patients.... Abstract
Cited 5 times since 2013 (0.5 per year) source: EuropePMC
Heart and vessels, Volume 29, Issue 5, 27 4 2013, Pages 619-628 Prognostic implications of left ventricular regional function heterogeneity assessed with two-dimensional speckle tracking in patients with ST-segment elevation myocardial infarction and depressed left ventricular ejection fraction. Hoogslag GE, Thijssen J, Höke U, Boden H, Antoni ML, Debonnaire P, Haeck ML, Holman ER, Bax JJ, Ajmone Marsan N, Schalij MJ, Delgado V
The aim of the current study was to evaluate the prognostic implications of myocardial tissue heterogeneity assessed with two-dimensional speckle-tracking echocardiography in patients three months after first ST-segment elevation myocardial infarction (STEMI) with left ventricular ejection fraction (LVEF) ≤35 %. For this purpose, a total of 79 patients with first STEMI and LVEF ≤35 % at three months postinfarction were evaluated. Based on left ventricular (LV) speckle-tracking longitudinal strai... Abstract
Cited 16 times since 2013 (1.5 per year) source: Scopus
The American journal of cardiology, Volume 112, Issue 11, 13 2 2013, Pages 1800-1806 Multidetector row computed tomography parameters associated with paravalvular regurgitation after transcatheter aortic valve implantation. Katsanos S, Ewe SH, Debonnaire P, van der Kley F, de Weger A, Palmen M, Scholte AJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Multidetector row computed tomographic (MDCT) assessment of aortic annulus dimensions and frame position and deployment have been associated with paravalvular aortic regurgitation (PAVR) after transcatheter aortic valve implantation (TAVI). The present evaluation investigated the (pre- and postprocedure) MDCT associates of PAVR ≥2+. In total, 123 patients referred for TAVI underwent clinical evaluation, transthoracic echocardiography, and pre- and post-TAVI MDCT. Pre-TAVI MDCT measurements of th... Abstract
Cited 42 times since 2013 (3.9 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 26, Issue 9, 13 2 2013, Pages 1053-1062 Left atrial function by two-dimensional speckle-tracking echocardiography in patients with severe organic mitral regurgitation: association with guidelines-based surgical indication and postoperative (long-term) survival. Debonnaire P, Leong DP, Witkowski TG, Al Amri I, Joyce E, Katsanos S, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: Left atrial (LA) mechanics in patients with severe mitral regurgitation (MR) remain largely unexplored. The aim of the present evaluation was to assess the effect of severe MR on LA function, its potential relation with conventional surgical indications, and long-term postoperative survival. Methods: Two-dimensional speckle-tracking strain and volumetric indices of LA reservoir, conduit, and contractile function were assessed in 121 patients with severe MR and 70 controls. Patients w... Abstract
Cited 11 times since 2013 (1 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 36, Issue 11, 4 1 2013, Pages 1391-1401 Clinical, echocardiographic, and neurohormonal response to cardiac resynchronization therapy: are they interchangeable? Hoogslag GE, Höke U, Thijssen J, Auger D, Marsan NA, Wolterbeek R, Holman ER, Schalij MJ, Bax JJ, Verwey HF, Delgado V
Background: The relationship between changes in N-terminal pro-brain natriuretic peptide (NT-proBNP) and echocardiographic or clinical definitions of response to cardiac resynchronization therapy (CRT) has not been evaluated. The aims of the present evaluation were to assess: (1) the relationship between changes in NT-proBNP after 6 months of CRT and clinical and echocardiographic responses; (2) the association between NT-proBNP changes and long-term outcome. Methods: In 170 patients treated wit... Abstract
Cited 12 times since 2013 (1.1 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 21, Issue 7-8, 1 1 2013, Pages 347-353 Different value of coronary calcium score to predict obstructive coronary artery disease in patients with and without moderate chronic kidney disease. Yiu KH, de Graaf FR, van Velzen JE, Marsan NA, Roos CJ, de Bie MK, Tse HF, van der Wall EE, Schalij MJ, Bax JJ, Schuijf JD, Jukema JW
Purpose: The coronary calcium score (CCS) predicts significant coronary artery disease (CAD) in the general population. While moderate chronic kidney disease (CKD) is associated with high CCS, the use of CCS to predict significant CAD in these patients is unknown. Methods: A total of 704 patients underwent computed tomography coronary angiography for the assessment of CCS and CAD. Sixty-nine (10 %) patients had moderate CKD, defined by an estimated glomerular filtration rate (eGFR) between 30 an... Abstract
Cited 5 times since 2013 (0.5 per year) source: Scopus
The American journal of cardiology, Volume 112, Issue 5, 24 4 2013, Pages 714-719 Mitral valve geometry and hemodynamics after surgical mitral valve annuloplasty and implications for percutaneous treatment of patients with recurrent mitral regurgitation. Al Amri I, Debonnaire P, Witkowski T, van der Kley F, Palmen M, de Weger A, Klautz RJ, Bax JJ, Schalij MJ, Ajmone Marsan N, Delgado V
The feasibility of transcatheter mitral valve therapy (edge-to-edge or valve-in-ring technique) in patients with significant mitral regurgitation (MR) recurrence after surgical restrictive mitral valve annuloplasty remains unknown. The aim of the present study was to investigate the eligibility for transcatheter mitral valve therapy of high-surgical-risk patients with significant MR recurrence after initial successful restrictive mitral valve annuloplasty. A total of 47 patients (age 67 ± 10 yea... Abstract
Cited 33 times since 2013 (3 per year) source: EuropePMC
The American journal of cardiology, Volume 112, Issue 4, 15 3 2013, Pages 560-566 Accuracy of three-dimensional versus two-dimensional echocardiography for quantification of aortic regurgitation and validation by three-dimensional three-directional velocity-encoded magnetic resonance imaging. Ewe SH, Delgado V, van der Geest R, Westenberg JJ, Haeck ML, Witkowski TG, Auger D, Marsan NA, Holman ER, de Roos A, Schalij MJ, Bax JJ, Sieders A, Siebelink HM
Quantitative assessment of aortic regurgitation (AR) remains challenging. The present study evaluated the accuracy of 2-dimensional (2D) and 3-dimensional (3D) transthoracic echocardiography (TTE) for AR quantification, using 3D 3-directional velocity-encoded magnetic resonance imaging (VE-MRI) as the reference method. Thirty-two AR patients were included. With color Doppler TTE, 2D effective regurgitant orifice area (EROA) was calculated using the proximal isovelocity surface area method. From... Abstract
Cited 23 times since 2013 (2.1 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 26, Issue 7, 11 2 2013, Pages 691-698 Impact of valvuloarterial impedance on 2-year outcome of patients undergoing transcatheter aortic valve implantation. Katsanos S, Yiu KH, Clavel MA, Rodés-Cabau J, Leong D, van der Kley F, Ajmone Marsan N, Bax JJ, Pibarot P, Delgado V
Background: Elderly patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) often have increased calcification and fibrosis of the aorta. Indices that account for the severity of valvular obstruction and systemic vascular impedance may better assess total left ventricular afterload. The aims of the present study were to evaluate changes in valvuloarterial impedance (Zva), systemic arterial compliance, and systemic vascular resistance after TAVI and to inves... Abstract
Cited 23 times since 2013 (2.1 per year) source: Scopus
European journal of heart failure, Volume 15, Issue 9, 10 2 2013, Pages 1011-1018 Galectin-3 and left ventricular reverse remodelling after surgical mitral valve repair. Kortekaas KA, Hoogslag GE, de Boer RA, Dokter MM, Versteegh MI, Braun J, Marsan NA, Verwey HF, Delgado V, Schalij MJ, Klautz RJ
Aims: Mitral valve repair in patients with functional mitral regurgitation (FMR) has been associated with beneficial left ventricular (LV) reverse remodelling. Recently, galectin-3 emerged as a marker of myocardial inflammation and fibrosis which may influence LV remodelling after surgery. The aim of the current study was to evaluate the association between pre-operative galectin-3 levels and LV reverse remodelling in heart failure patients with significant FMR who underwent mitral valve repair.... Abstract
Cited 4 times since 2013 (0.4 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 99, Issue 8, 6 1 2013, Pages 556-561 Association between discharge heart rate and left ventricular adverse remodelling in ST segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention. Joyce E, Hoogslag GE, Leong DP, Fox K, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Objective: Left ventricular (LV) adverse remodelling is an important determinant of mortality after ST segment elevation myocardial infarction (STEMI). Recently, discharge heart rate (DHR) has been associated with long-term outcomes after STEMI. Whether DHR is related to the development of LV remodelling after STEMI remains unknown. The present study evaluated the association between DHR after STEMI and the occurrence of LV remodelling at 6 months. DESIGN, SETTING, PATIENTS AND INTERVENTIONS: In... Abstract
Cited 2 times since 2013 (0.2 per year) source: EuropePMC
European heart journal, Volume 34, Issue 17, 7 1 2013, Pages 1278 The invisible made visible: multi-modality imaging in the evaluation of cardiac sarcoidosis. Joyce E, Delgado V, Ninaber MK, Marsan NA
Cited 8 times since 2013 (0.7 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 15, Issue 5, 22 4 2013, Pages 690-696 Duty-cycled bipolar/unipolar radiofrequency ablation for symptomatic atrial fibrillation induces significant pulmonary vein narrowing at long-term follow-up. Compier MG, Leong DP, Marsan NA, Delgado V, Zeppenfeld K, Schalij MJ, Trines SA
Aims: A novel duty-cycled bipolar/unipolar ablation catheter pulmonary vein ablation catheter (PVAC) has been developed to achieve pulmonary vein (PV) isolation in patients with atrial fibrillation (AF). Ablation with PVAC was recently found to induce PV narrowing at 3 months follow-up. The long-term effects of this catheter on PV dimensions are however unknown and were evaluated with this study. Methods and results: Patients (n = 62, 71% male, age 60 ± 7 years) with drug-refractory AF scheduled... Abstract
Cited 24 times since 2013 (2.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 99, Issue 10, 12 2 2013, Pages 722-728 Right ventricular function and survival following cardiac resynchronisation therapy. Leong DP, Höke U, Delgado V, Auger D, Witkowski T, Thijssen J, van Erven L, Bax JJ, Schalij MJ, Marsan NA
Objectives: Right ventricular (RV) function is an important prognostic marker in heart failure. However, its impact on all-cause mortality following cardiac resynchronisation therapy (CRT) independent of confounding factors has not been evaluated. Furthermore, evidence concerning the effect of CRT on RV function is limited. The study's aims were to: (1) assess the prognostic importance of RV function among CRT recipients, and (2) characterise RV functional change following CRT and its deter... Abstract