Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
154 results
Cited 140 times since 2009 (9.7 per year) source: EuropePMC
European heart journal, Volume 30, Issue 24, 1 1 2009, Pages 3037-3047 Strain analysis in patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing surgical valve replacement. Delgado V, Tops LF, van Bommel RJ, van der Kley F, Marsan NA, Klautz RJ, Versteegh MI, Holman ER, Schalij MJ, Bax JJ
Aims: To evaluate myocardial multidirectional strain and strain rate (S-and-SR) in severe aortic stenosis (AS) patients with preserved left ventricular (LV) ejection fraction (EF), using two-dimensional speckle-tracking strain imaging (2D-STI). The long-term effect of aortic valve replacement (AVR) on S-and-SR was also evaluated. Methods and results: Changes in LV radial, circumferential, and longitudinal S-and-SR were evaluated in 73 severe AS patients (65 +/- 13 years; aortic valve area 0.8 +/... Abstract
Cited 22 times since 2009 (1.5 per year) source: EuropePMC
American heart journal, Volume 158, Issue 5, 1 1 2009, Pages 769-776 Cardiac resynchronization therapy in patients with ischemic versus non-ischemic heart failure: Differential effect of optimizing interventricular pacing interval. Marsan NA, Bleeker GB, Van Bommel RJ, Borleffs C, Bertini M, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Background: Whether sequential biventricular pacing provides substantial benefits over conventional simultaneous stimulation remains unclear, particularly regarding the differences between ischemic and non-ischemic patients. The purpose of this study was to evaluate the acute effect of interventricular pacing interval (V-V) optimization on left ventricular (LV) systolic performance and dyssynchrony in ischemic versus non-ischemic patients. Methods: Sixty-nine consecutive patients underwent cardi... Abstract
Cited 11 times since 2009 (0.8 per year) source: EuropePMC
Coronary artery disease, Volume 20, Issue 7, 1 1 2009, Pages 462-466 Value of contrast echocardiography for left ventricular thrombus detection postinfarction and impact on antithrombotic therapy. Siebelink HM, Scholte AJ, Van de Veire NR, Holman ER, Nucifora G, van der Wall EE, Bax JJ
Introduction: Conventional echocardiography is often inconclusive for the presence or the absence of left ventricular (LV) thrombus. Contrast echocardiography could have additional diagnostic and therapeutic significance. This analysis investigated the value of contrast echocardiography for LV thrombus detection in patients postinfarction and the impact on choice of antithrombotic therapy. Methods: From a cohort of 991 patients undergoing routine echocardiography postinfarction, 156 patients who... Abstract
Cited 23 times since 2009 (1.6 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 95, Issue 22, 1 1 2009, Pages 1881-1890 Real-time three dimensional echocardiography: current and future clinical applications. Marsan NA, Tops LF, Nihoyannopoulos P, Holman ER, Bax JJ
Cited 55 times since 2009 (3.8 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 1, 9 2 2009, Pages 15-23 Viability assessment with global left ventricular longitudinal strain predicts recovery of left ventricular function after acute myocardial infarction. Mollema SA, Delgado V, Bertini M, Antoni ML, Boersma E, Holman ER, Stokkel MP, van der Wall EE, Schalij MJ, Bax JJ
Background: The extent of viable myocardial tissue is recognized as a major determinant of recovery of left ventricular (LV) function after myocardial infarction. In the current study, the role of global LV strain assessed with novel automated function imaging (AFI) to predict functional recovery after acute infarction was evaluated. Methods and results: A total of 147 patients (mean age, 61+/-11 years) admitted for acute myocardial infarction were included. All patients underwent 2D echocardiog... Abstract
Cited 69 times since 2009 (4.7 per year) source: EuropePMC
American heart journal, Volume 158, Issue 5, 3 1 2009, Pages 836-844 Incremental value of 2-dimensional speckle tracking strain imaging to wall motion analysis for detection of coronary artery disease in patients undergoing dobutamine stress echocardiography. Ng AC, Sitges M, Pham PN, Tran da T, Delgado V, Bertini M, Nucifora G, Vidaic J, Allman C, Holman ER, Bax JJ, Leung DY
Background: Interpretation of dobutamine stress echocardiogram (DSE) is often subjective and requires expert training. The purposes of this study was to determine optimal cutoff values for longitudinal, circumferential, and radial strains at peak DSE for detection of significant stenoses on coronary angiography and to investigate incremental value of combining strain measurements to wall motion analysis. Methods: In this multicenter study, 102 patients underwent concomitant DSE and coronary angi... Abstract
Cited 45 times since 2009 (3.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 54, Issue 14, 1 1 2009, Pages 1317-1325 Effects of cardiac resynchronization therapy on left ventricular twist. Bertini M, Marsan NA, Delgado V, van Bommel RJ, Nucifora G, Borleffs CJ, Boriani G, Biffi M, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Objectives: This study explored the effects of cardiac resynchronization therapy (CRT) on left ventricular (LV) twist, particularly in relation to LV lead position. Background: LV twist is emerging as a comprehensive index of LV function. Methods: Eighty heart failure patients were included. Two-dimensional echocardiography was performed at baseline, immediately after CRT, and at 6-month follow-up. Speckle-tracking analysis was applied to assess LV twist. The LV lead was placed preferably in a (... Abstract
Cited 55 times since 2009 (3.7 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 25, Issue 7, 30 5 2009, Pages 669-676 Right ventricular peak systolic longitudinal strain is a sensitive marker for right ventricular deterioration in adult patients with tetralogy of Fallot. Scherptong RW, Mollema SA, Blom NA, Kroft LJ, de Roos A, Vliegen HW, van der Wall EE, Bax JJ, Holman ER
The aim of this study was to evaluate the feasibility of right ventricular (RV) longitudinal peak systolic strain (LPSS) assessment for the follow-up of adult patients with corrected tetralogy of Fallot (TOF). Adult patients (n = 18) with corrected TOF underwent echocardiography and CMR twice with a time interval of 4.2 +/- 1.7 years. RV performance was derived from CMR, and included RV volumes and ejection fraction (EF). LPSS was calculated globally (GLPSS) and in the RV free wall (LPSS FW), wi... Abstract
Cited 15 times since 2009 (1 per year) source: EuropePMC
The American journal of cardiology, Volume 104, Issue 4, 17 3 2009, Pages 480-485 Impact of time to reperfusion after acute myocardial infarction on myocardial damage assessed by left ventricular longitudinal strain. Bertini M, Mollema SA, Delgado V, Antoni ML, Ng AC, Holman ER, Boriani G, Schalij MJ, Bax JJ
The relation between cardiac troponin T (cTnT) and regional strain in patients with acute myocardial infarction (AMI) was investigated. Furthermore, the effect of symptoms-to-balloon time on impairment in regional strain after AMI was evaluated. A total of 157 consecutive patients with AMI who underwent primary percutaneous coronary intervention were included. Two-dimensional echocardiography soon after percutaneous coronary intervention was performed. Speckle-tracking analysis was applied to as... Abstract
Cited 32 times since 2009 (2.1 per year) source: EuropePMC
The American journal of cardiology, Volume 103, Issue 11, 8 2 2009, Pages 1506-1512 Left ventricular rotational mechanics in acute myocardial infarction and in chronic (ischemic and nonischemic) heart failure patients. Bertini M, Nucifora G, Marsan NA, Delgado V, van Bommel RJ, Boriani G, Biffi M, Holman ER, Van der Wall EE, Schalij MJ, Bax JJ
Left ventricular (LV) twist and untwisting rate are emerging as global and thorough parameters for assessment of LV function. This study explored differences of LV twist and untwisting rate in patients with acute myocardial infarction (AMI) and patients with ischemic and nonischemic chronic heart failure (HF). Fifty patients with AMI, 49 with ischemic HF, and 38 with nonischemic HF were studied. As a control group, 28 subjects without evidence of structural heart disease were included. Speckle-t... Abstract
Cited 22 times since 2009 (1.5 per year) source: Scopus
JACC. Cardiovascular imaging, Volume 2, Issue 4, 1 1 2009, Pages 522-523 Percutaneous valve-in-valve procedure for severe paravalvular regurgitation in aortic bioprosthesis. Ng AC, van der Kley F, Delgado V, Shanks M, van Bommel RJ, de Weger A, Tavilla G, Holman ER, Schuijf JD, van de Veire NR, Schalij MJ, Bax JJ
Cited 14 times since 2009 (0.9 per year) source: EuropePMC
Arthritis and rheumatism, Volume 60, Issue 4, 1 1 2009, Pages 987-993 No increased risk of valvular heart disease in adult poststreptococcal reactive arthritis. van Bemmel JM, Delgado V, Holman ER, Allaart CF, Huizinga TW, Bax JJ, van der Helm-van Mil AH
Objective: Poststreptococcal reactive arthritis (ReA) is a (poly)arthritis presenting after a Streptococcus group A infection. Acute rheumatic fever (ARF), albeit caused by the same pathogen, has different risk characteristics and is considered to be a separate entity. Whereas ARF is known to cause carditis, the risk of carditis in adult poststreptococcal ReA is unknown. Consequently, the prevailing recommendations regarding long-term antibiotic prophylaxis in poststreptococcal ReA are imprecise... Abstract
Cited 2 times since 2009 (0.1 per year) source: EuropePMC
American heart journal, Volume 157, Issue 5, 25 4 2009, Pages 882.e1-8 Real-time 3-dimensional echocardiography early after acute myocardial infarction: incremental value of echo-contrast for assessment of left ventricular function. Nucifora G, Marsan NA, Holman ER, Siebelink HM, van Werkhoven JM, Scholte AJ, van der Wall EE, Schalij MJ, Bax JJ
Background: Accurate and reproducible assessment of left ventricular (LV) systolic function is important in patients with acute myocardial infarction (AMI). Real-time 3-dimensional echocardiography (RT3DE) is an accurate technique, but it relies heavily on good image quality. The aim of the present study was to evaluate the incremental value of contrast-enhanced RT3DE. Methods: A total of 140 consecutive patients (58 +/- 11 years, 78% men) with ST-elevation AMI clinically underwent nonenhanced a... Abstract
Cited 22 times since 2009 (1.5 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 35, Issue 5, 9 2 2009, Pages 847-52; discussion 852-3 Wall motion score index predicts mortality and functional result after surgical ventricular restoration for advanced ischemic heart failure. Klein P, Holman ER, Versteegh MI, Boersma E, Verwey HF, Bax JJ, Dion RA, Klautz RJ
Objective: Advanced ischemic heart failure can be treated with surgical ventricular restoration (SVR). While numerous risk factors for mortality and recurrent heart failure have been identified, no plain predictor for identifying SVR patients with left ventricular damage beyond recovery is yet available. We tested echocardiographic wall motion score index (WMSI) as a predictor for mortality or poor functional result. Methods: One hundred and one patients electively operated between April 2002 an... Abstract
Cited 44 times since 2009 (2.9 per year) source: EuropePMC
Circulation, Volume 119, Issue 11, 9 2 2009, Pages 1467-1472 Tricuspid valve surgery in adults with a dysfunctional systemic right ventricle: repair or replace? Scherptong RW, Vliegen HW, Winter MM, Holman ER, Mulder BJ, van der Wall EE, Hazekamp MG
Background: In patients with a right ventricle (RV) in the systemic position, tricuspid valve surgery for regurgitation beyond adolescence is a subject of debate. The aim of the present study was to evaluate the complications, survival, and benefit of tricuspid surgery in adult patients with an atrium-level correction for transposition of the great arteries or congenitally corrected transposition of the great arteries. Methods and results: All adult patients (n=16; 7 men, 9 women; age 35+/-11 ye... Abstract
Cited 15 times since 2009 (1 per year) source: EuropePMC
The American journal of cardiology, Volume 103, Issue 8, 25 4 2009, Pages 1045-1050 Usefulness of echocardiographic assessment of cardiac and ascending aorta calcific deposits to predict coronary artery calcium and presence and severity of obstructive coronary artery disease. Nucifora G, Schuijf JD, van Werkhoven JM, Jukema JW, Marsan NA, Holman ER, van der Wall EE, Bax JJ
The presence of cardiac and aortic calcific deposits has been related to coronary artery disease (CAD) and cardiovascular events. The present study aimed to evaluate whether comprehensive echocardiographic assessment of cardiac and ascending aorta calcific deposits could predict coronary calcium and obstructive CAD. A total of 140 outpatients (age 61 +/- 11 years; 90 men) without a history of CAD were studied. Aortic valve sclerosis and mitral annular, papillary muscle, and ascending aorta calci... Abstract
Cited 79 times since 2009 (5.2 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 2, 18 3 2009, Pages 135-145 Acute effects of right ventricular apical pacing on left ventricular synchrony and mechanics. Delgado V, Tops LF, Trines SA, Zeppenfeld K, Marsan NA, Bertini M, Holman ER, Schalij MJ, Bax JJ
Background: Chronic right ventricular (RV) apical pacing has a detrimental effect on left ventricular (LV) function. However, the acute effects of RV apical pacing on LV mechanics remain unclear. The purpose of the study was to assess the acute impact of RV apical pacing on global LV function, evaluating LV contraction synchrony and LV shortening and twist, using 2D speckle-tracking strain imaging. Methods and results: A group of 25 patients with structural normal hearts referred for electrophys... Abstract
Cited 34 times since 2008 (2.2 per year) source: EuropePMC
The American journal of cardiology, Volume 103, Issue 5, 26 4 2008, Pages 690-694 Comparison of time course of response to cardiac resynchronization therapy in patients with ischemic versus nonischemic cardiomyopathy. Marsan NA, Bleeker GB, van Bommel RJ, Ypenburg C, Delgado V, Borleffs CJ, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
The time course of the effects of cardiac resynchronization therapy (CRT) on left ventricular (LV) systolic function and reverse remodeling is still unknown and was the subject of this study. In particular, whether the acute benefit of CRT translates in late response was explored. Furthermore, the time course of response was compared between ischemic and nonischemic patients. A total of 222 consecutive patients with heart failure (135 ischemic) scheduled for CRT were included. Standard echocardi... Abstract
Cited 8 times since 2008 (0.5 per year) source: EuropePMC
European journal of endocrinology, Volume 159, Issue 6, 11 2 2008, Pages 705-712 Cardiac manifestations of GH deficiency after treatment for acromegaly: a comparison to patients with biochemical remission and controls. van der Klaauw AA, Bax JJ, Bleeker GB, Holman ER, Delgado V, Smit JW, Romijn JA, Pereira AM
Objective: Both GH excess and GH deficiency (GHD) lead to specific cardiac pathology. The aim of this study was to evaluate cardiac morphology and function in patients with GHD after treatment for acromegaly. Design: Cross-sectional study. Patients and methods: Cardiac parameters were studied by conventional two-dimensional echocardiography and tissue Doppler imaging in 53 patients with acromegaly (16 patients with GHD, 20 patients with biochemical remission, and 17 patients with active disease)... Abstract
Cited 29 times since 2008 (1.9 per year) source: EuropePMC
The American journal of cardiology, Volume 102, Issue 10, 6 1 2008, Pages 1366-1372 Comparison between tissue Doppler imaging and velocity-encoded magnetic resonance imaging for measurement of myocardial velocities, assessment of left ventricular dyssynchrony, and estimation of left ventricular filling pressures in patients with ischemic cardiomyopathy. Marsan NA, Westenberg JJ, Tops LF, Ypenburg C, Holman ER, Reiber JH, de Roos A, van der Wall EE, Schalij MJ, Roelandt JR, Bax JJ
Velocity-encoded magnetic resonance imaging (VE-MRI), commonly used to perform flow measurements, can be applied for myocardial velocity analysis, similar to tissue Doppler imaging (TDI). In this study, a comparison between VE-MRI and TDI was performed for the assessment of left ventricular dyssynchrony and left ventricular filling pressures. Ten healthy volunteers and 22 patients with heart failure secondary to ischemic cardiomyopathy underwent both VE-MRI and TDI. Longitudinal myocardial peak... Abstract