Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
154 results
Cited 16 times since 2010 (1.2 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 90, Issue 6, 1 1 2010, Pages 1913-1920 Clinical and functional effects of restrictive mitral annuloplasty at midterm follow-up in heart failure patients. ten Brinke EA, Klautz RJ, Tulner SA, Verwey HF, Bax JJ, Delgado V, Holman ER, Schalij MJ, van der Wall EE, Braun J, Versteegh MI, Dion RA, Steendijk P
Background: Restrictive mitral annuloplasty (RMA) is increasingly applied to treat functional mitral regurgitation in heart failure patients. Previous studies indicated beneficial clinical effects with low recurrence rates. However, the underlying pathophysiology is complex and outcome in terms of left ventricular function is not well known. We investigated chronic effects of RMA on ventricular function in relation to clinical outcome. Methods: Heart failure patients (n = 11) with severe mitral... Abstract
Cited 11 times since 2010 (0.8 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 10, 1 1 2010, Pages 1404-1409 Left ventricular muscle and fluid mechanics in acute myocardial infarction. Nucifora G, Delgado V, Bertini M, Marsan NA, Van de Veire NR, Ng AC, Siebelink HM, Schalij MJ, Holman ER, Sengupta PP, Bax JJ
Left ventricular (LV) diastolic filling is characterized by the formation of intraventricular rotational bodies of fluid (termed "vortex rings") that optimize the efficiency of LV ejection. The aim of the present study was to evaluate the morphology and dynamics of LV diastolic vortex ring formation early after acute myocardial infarction (AMI), in relation to LV diastolic function and infarct size. A total of 94 patients with a first ST-segment elevation AMI (59 ± 11 years; 78% men) w... Abstract
Cited 18 times since 2010 (1.3 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 56, Issue 19, 1 1 2010, Pages 1567-1575 Effect of biventricular pacing on diastolic dyssynchrony. Shanks M, Bertini M, Delgado V, Ng AC, Nucifora G, van Bommel RJ, Borleffs CJ, Holman ER, van de Veire NR, Schalij MJ, Bax JJ
Objectives: This study sought to examine the changes in diastolic dyssynchrony with cardiac resynchronization therapy (CRT). Background: Little is known about the effect of CRT on diastolic dyssynchrony. Methods: Consecutive heart failure patients (n = 266, age 65.7 ± 10.0 years) underwent color-coded tissue Doppler imaging at baseline, 48 h, and 6 months after CRT. Systolic and diastolic dyssynchrony were defined as maximal time delay in peak systolic and early diastolic velocities, respectivel... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 1, 24 4 2010, Pages 101-104 Speckle tracking: distinction of physiologic from pathologic LVH? van der Wall EE, Delgado V, Holman ER, Bax JJ
Cited 52 times since 2010 (3.8 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 16, 1 1 2010, Pages 1275-1280 Beneficial effects of catheter ablation on left ventricular and right ventricular function in patients with frequent premature ventricular contractions and preserved ejection fraction. Wijnmaalen AP, Delgado V, Schalij MJ, van Huls van Taxis CF, Holman ER, Bax JJ, Zeppenfeld K
Background: Improvement of left ventricular ejection fraction (LVEF) after radiofrequency catheter ablation (RFCA) of frequent premature ventricular contractions (PVCs) has been reported. However, most patients with frequent PVCs have a normal LVEF. In these patients subtle and early forms of PVC-induced left and right ventricular (RV) impairment may not be detected by standard echocardiographic techniques. Objective: To assess the effect of frequent PVCs on ventricular function in patients with... Abstract
Cited 37 times since 2010 (2.7 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 5, 23 4 2010, Pages 723-729 Relation of left ventricular twist and global strain with right ventricular dysfunction in patients after operative "correction" of tetralogy of fallot. van der Hulst AE, Delgado V, Holman ER, Kroft LJ, de Roos A, Hazekamp MG, Blom NA, Bax JJ, Roest AA
In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse ventricular-ventricular interactions. However, the mechanism that links RV dysfunction to LV dysfunction remains unclear. In this prospective study, 32 patients with cToF and 19 controls were enrolled. With cardiac magnetic resonance imaging, biventricular ejection fractions were assessed. Using 2-dimensional speckle tracking, globa... Abstract
Cited 15 times since 2010 (1.1 per year) source: EuropePMC
European journal of endocrinology, Volume 163, Issue 3, 29 5 2010, Pages 435-441 Abnormal cardiac contractility in long-term exogenous subclinical hyperthyroid patients as demonstrated by two-dimensional echocardiography speckle tracking imaging. Abdulrahman RM, Delgado V, Ng AC, Ewe SH, Bertini M, Holman ER, Hovens GC, Pereira AM, Romijn JA, Bax JJ, Smit JW
Background: Subclinical hyperthyroidism is associated with cardiovascular morbidity. Recent advances in echocardiography imaging have allowed sophisticated evaluation of myocardial tissue properties. Objective: To investigate the myocardial effects of long-term exogenous subclinical hyperthyroidism using two-dimensional speckle tracking echocardiography imaging (2D-STE). Design: Prospective, single-blinded, placebo-controlled randomized trial of 6 months duration with two parallel groups. Patien... Abstract
Cited 30 times since 2010 (2.2 per year) source: EuropePMC
European heart journal, Volume 31, Issue 16, 20 3 2010, Pages 2006-2013 Time course of global left ventricular strain after acute myocardial infarction. Antoni ML, Mollema SA, Atary JZ, Borleffs CJ, Boersma E, van de Veire NR, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Aims: The purpose of the present study was to assess the evolution of left ventricular (LV) function after acute myocardial infarction (AMI) using global longitudinal peak systolic strain (GLPSS) during 1 year follow-up. In addition, patients were divided in groups with early, late, or no improvement of LV function and predictors of recovery of LV function were established. Methods and results: A total of 341 patients with AMI were evaluated. Two-dimensional echocardiography was performed at bas... Abstract
Cited 33 times since 2010 (2.4 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 2, 9 2 2010, Pages 198-203 Predictive value of total atrial conduction time estimated with tissue Doppler imaging for the development of new-onset atrial fibrillation after acute myocardial infarction. Antoni ML, Bertini M, Atary JZ, Delgado V, ten Brinke EA, Boersma E, Holman ER, van der Wall EE, Schalij MJ, Bax JJ, van de Veire NR
Patients who develop new-onset atrial fibrillation (AF) after acute myocardial infarction (AMI) show an increased risk for adverse events and mortality during follow-up. Recently, a novel noninvasive echocardiographic method has been validated for the estimation of total atrial activation time using tissue Doppler imaging of the atria (PA-TDI duration). PA-TDI duration has shown to be independently predictive of new-onset AF. However, whether PA-TDI duration provides predictive value for new-ons... Abstract
Cited 4 times since 2010 (0.3 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 26, Issue 5, 1 1 2010, Pages 537-540 Echocardiography in Takotsubo cardiomyopathy; a useful approach? van der Wall EE, Holman ER, Scholte AJ, Bax JJ
Cited 31 times since 2010 (2.2 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 4, 17 3 2010, Pages 433-442 Reduced left ventricular torsion early after myocardial infarction is related to left ventricular remodeling. Nucifora G, Marsan NA, Bertini M, Delgado V, Siebelink HM, van Werkhoven JM, Scholte AJ, Schalij MJ, van der Wall EE, Holman ER, Bax JJ
Background: Left ventricular (LV) torsion is emerging as a sensitive parameter of LV systolic myocardial performance. The aim of the present study was to explore the effects of acute myocardial infarction (AMI) on LV torsion and to determine the value of LV torsion early after AMI in predicting LV remodeling at 6-month follow-up. Methods and results: A total of 120 patients with a first ST-segment elevation AMI (mean+/-SD age, 59+/-10 years; 73% male) were included. All patients underwent primar... Abstract
Cited 2 times since 2010 (0.1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 7, 8 2 2010, Pages 939-942 Stress imaging in patients with diabetes; routine practice? van der Wall EE, Scholte AJ, Holman ER, Bax JJ
Cited 104 times since 2010 (7.4 per year) source: EuropePMC
European heart journal, Volume 31, Issue 13, 27 4 2010, Pages 1640-1647 Prognostic importance of strain and strain rate after acute myocardial infarction. Antoni ML, Mollema SA, Delgado V, Atary JZ, Borleffs CJ, Boersma E, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Aims: Recently, strain and strain rate have been introduced as novel parameters reflecting left ventricular (LV) function. The purpose of the current study was to assess the prognostic importance of strain and strain rate after acute myocardial infarction (AMI). Methods and results: A total of 659 patients after AMI were evaluated. Baseline echocardiography was performed to assess LV function with traditional parameters and strain and strain rate. During follow-up, 51 patients (8%) reached the p... Abstract
Cited 13 times since 2010 (0.9 per year) source: EuropePMC
BMC geriatrics, Volume 10, 1 1 2010, Pages 17 Impact of valvular heart disease on activities of daily living of nonagenarians: the Leiden 85-plus study a population based study. van Bemmel T, Delgado V, Bax JJ, Gussekloo J, Blauw GJ, Westendorp RG, Holman ER
Background: Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown. The present study evaluated the prevalence of significant valvular heart disease and the impact of valvular heart disease on the activities of daily living in community dwelling nonagenarians. Nested within the Leiden 85-plus study, a population... Abstract
Cited 87 times since 2010 (6.1 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 3, Issue 3, 27 4 2010, Pages 264-271 Prognostic value of right ventricular function in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Antoni ML, Scherptong RW, Atary JZ, Boersma E, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Background: Data on the association between right ventricular (RV) function and adverse events after acute myocardial infarction (AMI) are scarce. The purpose of the current study was to evaluate the relation between RV function and adverse events in patients treated with primary percutaneous coronary intervention for AMI. Methods and results: Consecutive patients admitted with AMI treated with primary percutaneous coronary intervention underwent echocardiography within 48 hours of admission to... Abstract
Cited 22 times since 2010 (1.6 per year) source: EuropePMC
The American journal of cardiology, Volume 105, Issue 8, 20 3 2010, Pages 1153-1158 Value of tissue Doppler echocardiography in predicting response to cardiac resynchronization therapy in patients with heart failure. Van Bommel RJ, Ypenburg C, Borleffs CJ, Delgado V, Marsan NA, Bertini M, Holman ER, Schalij MJ, Bax JJ
Several studies have demonstrated a relation between left ventricular (LV) dyssynchrony and response to cardiac resynchronization therapy (CRT). Many methods of determining LV dyssynchrony have been proposed, including a value of 65 ms as assessed by tissue Doppler imaging. The aim of the present validation study was to prospectively test the predictive accuracy of the 65-ms cutoff for LV dyssynchrony in a large cohort of patients with heart failure undergoing CRT. The study included 361 patient... Abstract
Cited 9 times since 2010 (0.6 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 4, 1 1 2010, Pages 807-815 Noninvasive estimation of left ventricular filling pressures in patients with heart failure after surgical ventricular restoration and restrictive mitral annuloplasty. ten Brinke EA, Bertini M, Klautz RJ, Antoni ML, Holman ER, van de Veire NR, Bax JJ, Steendijk P
Objective: Doppler echocardiography, including tissue Doppler imaging, is widely applied to assess diastolic left ventricular function using early transmitral flow velocity combined with mitral annular velocity as a noninvasive estimate of left ventricular filling pressures. However, the accuracy of early transmitral flow velocity/mitral annular velocity in patients with heart failure, particularly after extensive cardiac surgery, is debated. Global diastolic strain rate during isovolumic relaxa... Abstract
Cited 32 times since 2010 (2.2 per year) source: EuropePMC
The American journal of cardiology, Volume 105, Issue 5, 22 4 2010, Pages 592-597 Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction. Shanks M, Ng AC, van de Veire NR, Antoni ML, Bertini M, Delgado V, Nucifora G, Holman ER, Choy JB, Leung DY, Schalij MJ, Bax JJ
This study examined the prognostic value of novel diastolic indexes in ST-elevation acute myocardial infarction (AMI), derived from strain and strain rate analysis using 2-dimensional speckle tracking imaging. Echocardiograms were obtained within 48 hours of admission in 371 consecutive patients with first ST-elevation AMI (59.7 +/- 11.6 years old). Indexes of diastolic function including mean strain rate during isovolumic relaxation (SR(IVR)), mean early diastolic strain rate (SR(E)) and mean d... Abstract
Cited 47 times since 2010 (3.3 per year) source: EuropePMC
American heart journal, Volume 159, Issue 1, 1 1 2010, Pages 148-157 Incremental value of subclinical left ventricular systolic dysfunction for the identification of patients with obstructive coronary artery disease. Nucifora G, Schuijf JD, Delgado V, Bertini M, Scholte AJ, Ng AC, van Werkhoven JM, Jukema JW, Holman ER, van der Wall EE, Bax JJ
Background: Left ventricular (LV) diastolic dysfunction and subclinical systolic dysfunction may be markers of coronary artery disease (CAD). However, whether these markers are useful for prediction of obstructive CAD is unknown. Methods: A total of 182 consecutive outpatients (54 +/- 10 years, 59% males) without known CAD and overt LV systolic dysfunction underwent 64-slice multislice computed tomography (MSCT) coronary angiography and echocardiography. The MSCT angiograms showing atheroscleros... Abstract
Cited 22 times since 2009 (1.5 per year) source: EuropePMC
The American journal of cardiology, Volume 105, Issue 3, 21 3 2009, Pages 306-311 Impact of left ventricular dyssynchrony early on left ventricular function after first acute myocardial infarction. Nucifora G, Bertini M, Marsan NA, Delgado V, Scholte AJ, Ng AC, van Werkhoven JM, Siebelink HM, Holman ER, Schalij MJ, van der Wall EE, Bax JJ
The impact of left ventricular (LV) dyssynchrony after acute myocardial infarction (AMI) on LV ejection fraction (EF) is unknown. One hundred twenty-nine patients with a first ST-elevation AMI (58 + or - 11 years, 78% men) and QRS duration Abstract