Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
154 results
Cited 25 times since 2005 (1.3 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 16, Issue 7, 1 1 2005, Pages 701-707 Long-term follow-up of cardiac resynchronization therapy in patients with end-stage heart failure. Molhoek SG, Bax JJ, Bleeker GB, Holman ER, Van Erven L, Bootsma M, Boersma E, Steendijk P, Van Der Wall EE, Schalij MJ
Unlabelled: Long-term follow-up of cardiac resynchronization therapy. Introduction: Cardiac resynchronization therapy (CRT) has been introduced to treat patients with end-stage heart failure, and results of this technique are promising. The aim of our study was to assess the sustained benefit of CRT in a large patient cohort with end-stage heart failure at long-term follow-up. In addition, the prognosis of responders and nonresponders was evaluated. Methods and results: 125 patients with end-sta... Abstract
Cited 124 times since 2005 (6.5 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 27, Issue 5, 1 1 2005, Pages 847-853 Preoperative left ventricular dimensions predict reverse remodeling following restrictive mitral annuloplasty in ischemic mitral regurgitation. Braun J, Bax JJ, Versteegh MI, Voigt PG, Holman ER, Klautz RJ, Boersma E, Dion RA
Objective: Ischemic mitral regurgitation can be treated with a restrictive mitral annuloplasty, with or without coronary revascularization. In this study, the extent of reverse remodeling of the left ventricle following this strategy is assessed, as well as the factors that influence it. Methods: Eighty-seven consecutive patients with ischemic mitral regurgitation and a mean ejection fraction of 32+/-10% underwent restrictive mitral annuloplasty (downsizing by two ring sizes, median ring size 26... Abstract
Cited 5 times since 2005 (0.3 per year) source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 6, Issue 5, 2 1 2005, Pages 388-391 Contrast echocardiography as a useful additional diagnostic tool in evaluating a primary cardiac tumor. Haverkamp MC, Scholte AJ, Holman ER, Jongbloed MR, Schippers EF, de Roos A, van der Wall EE, Poldermans D, Bax JJ, Schalij MJ
The current report describes a case of a primary cardiac lymphoma. For early and appropriate treatment of a cardiac mass it is not only important to determine its localization and extension but also to differentiate between malignant and benign lesions. This report demonstrates that not only transthoracic echocardiography but also the other different forms of echocardiography such as transesophageal echocardiography, as well as contrast and intracardiac echocardiography, are useful tools in the... Abstract
Cited 78 times since 2005 (4 per year) source: EuropePMC
The American journal of cardiology, Volume 95, Issue 1, 1 1 2005, Pages 140-142 Frequency of left ventricular dyssynchrony in patients with heart failure and a narrow QRS complex. Bleeker GB, Schalij MJ, Molhoek SG, Holman ER, Verwey HF, Steendijk P, van der Wall EE, Bax JJ
Cardiac resynchronization therapy (CRT) is considered a major advance in the treatment of patients with heart failure. The presence of left ventricular (LV) dyssynchrony seems mandatory for a positive response to CRT. Currently, only patients with wide QRS complexes are considered for CRT, although patients with narrow QRS complexes may also have LV dyssynchrony. In the present study, the incidence of LV dyssynchrony was prospectively evaluated in 64 patients with heart failure and narrow QRS co... Abstract
Cited 5 times since 2004 (0.3 per year) source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 6, Issue 4, 20 3 2004, Pages 297-300 Underestimation of severity of mitral regurgitation with varying hemodynamics. Scholte AJ, Holman ER, Haverkamp MC, Poldermans D, van der Wall EE, Dion RA, Bax JJ
Transesophageal echocardiography (TEE) is a valuable technique to assess mitral valve anatomy and the mechanism of mitral regurgitation (MR). We present the case of a 35-year-old woman with severe MR due to restrictive motion of the posterior mitral leaflet, who was referred for mitral annuloplasty. Under physiologic circumstances, a severe (grade 3+) MR was present, whereas in the operating room during general anesthesia, the MR had disappeared almost completely. The downgrading of MR due to ge... Abstract
Cited 103 times since 2004 (5.2 per year) source: EuropePMC
Circulation, Volume 110, Issue 11 Suppl 1, 1 1 2004, Pages II103-8 Restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation results in reverse left ventricular remodeling. Bax JJ, Braun J, Somer ST, Klautz R, Holman ER, Versteegh MI, Boersma E, Schalij MJ, van der Wall EE, Dion RA
Background: Data on combined coronary artery bypass grafting (CABG) and restrictive annuloplasty in patients with ischemic cardiomyopathy are scarce, and the effect on reverse left ventricular (LV) remodeling is unknown. Methods and results: 51 patients with ischemic LV dysfunction (LV ejection fraction 31+/-8%) and severe mitral regurgitation (grade 3 to 4+) underwent CABG and restrictive annuloplasty with stringent downsizing of the mitral annulus (by 2 sizes, Physio-ring, mean size 28+/-2). S... Abstract
Cited 4 times since 2004 (0.2 per year) source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 5, Issue 3, 1 1 2004, Pages 231-236 Aortic valve regurgitation due to cusp aneurysm: a case report. Scholte AJ, Agema WR, Poldermans D, Somer ST, Holman ER, van der Wall EE, Bax JJ
Two-dimensional echocardiography is a valuable tool in visualizing and monitoring aortic valve and root abnormalities. We present a rare case of a patient with massive aortic regurgitation due to cusp aneurysm, which was accurately diagnosed by echocardiography and treated by valve replacement. A complicated course with recurrent aneurysms of the aortic wall after aortic valve replacement was remarkable in this case. Although different possible etiologies could not be determined, endocarditis an... Abstract
Cited 239 times since 2004 (12 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 15, Issue 5, 1 1 2004, Pages 544-549 Relationship between QRS duration and left ventricular dyssynchrony in patients with end-stage heart failure. Bleeker GB, Schalij MJ, Molhoek SG, Verwey HF, Holman ER, Boersma E, Steendijk P, Van Der Wall EE, Bax JJ
Introduction: Patients with end-stage heart failure and a wide QRS complex are considered candidates for cardiac resynchronization therapy (CRT). However, 20% to 30% of patients do not respond to CRT. Lack of left ventricular dyssynchrony may explain the nonresponse. Accordingly, we evaluated the presence of left ventricular dyssynchrony using tissue Doppler imaging (TDI) in 90 consecutive patients with heart failure. Methods and results: Ninety patients with severe heart failure (left ventricul... Abstract
Cited 93 times since 1997 (3.4 per year) source: EuropePMC
Circulation, Volume 95, Issue 4, 1 1 1997, Pages 924-931 Detection and quantification of dysfunctional myocardium by magnetic resonance imaging. A new three-dimensional method for quantitative wall-thickening analysis. Holman ER, Buller VG, de Roos A, van der Geest RJ, Baur LH, van der Laarse A, Bruschke AV, Reiber JH, van der Wall EE
Background: Regional left ventricular dysfunction is a major consequence of myocardial ischemia, and its extent determines long-term prognosis. Accurate and reproducible analysis of left ventricular dysfunction is therefore useful for risk stratification and patient management. Methods and results: Short-axis cardiac cine magnetic resonance (MR) imaging was performed in 25 patients after anterior myocardial infarction at 21 +/- 2.1 days after the acute onset. The MR images were analyzed with the... Abstract
Cited 16 times since 1996 (0.6 per year) source: EuropePMC
Magnetic resonance imaging, Volume 14, Issue 1, 1 1 1996, Pages 21-29 Assessment of acute myocardial infarction in man with magnetic resonance imaging and the use of a new paramagnetic contrast agent gadolinium-BOPTA. Holman ER, van Rossum AC, Doesburg T, van der Wall EE, de Roos A, Visser CA
To assess the feasibility of and characterize the new paramagnetic contrast agent gadolinium-BOPTA/dimeglumine (Gd-BOPTA) to detect acute myocardial infarctions with MR imaging, 24 patients (53.3 +/- 8.3 yr) were examined 9.3 +/- 3.6 days after a first myocardial infarction. Short-axis T1-weighted and T2-weighted MR imaging was performed at three slice levels. T1-weighted images were obtained before, immediately after, 15, 30, and 45 min after injection. Patients received either 0.05 or 0.1 mmol... Abstract
Cited 33 times since 1995 (1.1 per year) source: EuropePMC
Magnetic resonance in medicine, Volume 34, Issue 2, 1 1 1995, Pages 161-169 Quantitative analysis of regional left ventricular function after myocardial infarction in the pig assessed with cine magnetic resonance imaging. Holman ER, Vliegen HW, van der Geest RJ, Reiber JH, van Dijkman PR, van der Laarse A, de Roos A, van der Wall EE
To assess the accuracy of quantitative analysis of global and regional wall motion and wall thickening of the left ventricle with cine magnetic resonance (MR), images obtained in eight pigs before and after myocardial infarction were compared with those obtained using gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced multislice spin-echo MR imaging and determination of pathology. The region with abnormal wall motion and wall thickening, as determined with cine MR imaging, identifi... Abstract
Cited 56 times since 1993 (1.8 per year) source: EuropePMC
The American journal of cardiology, Volume 71, Issue 12, 1 1 1993, Pages 1036-1040 Comparison of magnetic resonance imaging studies with enzymatic indexes of myocardial necrosis for quantification of myocardial infarct size. Holman ER, van Jonbergen HP, van Dijkman PR, van der Laarse A, de Roos A, van der Wall EE
To evaluate the potential of gadolinium-diethylene triamine pentaacetic acid (DTPA)-enhanced magnetic resonance imaging (MRI) in the quantification of infarct size in patients with a first acute myocardial infarction, 24 patients with a first acute myocardial infarction were studied by electrocardiographic gated MRI at a mean of 4.3 days after the acute event. Multislice, single-phase, T1-weighted, spin-echo MRI in the true short-axis plane was performed 20 minutes after intravenous injection of... Abstract
Cited 83 times since 1993 (2.7 per year) source: EuropePMC
European heart journal, Volume 14, Issue 4, 1 1 1993, Pages 456-463 Quantitation of global and regional left ventricular function by cine magnetic resonance imaging during dobutamine stress in normal human subjects. van Rugge FP, Holman ER, van der Wall EE, de Roos A, van der Laarse A, Bruschke AV
Magnetic resonance imaging (MRI) provides high-resolution images of the heart. However, physical exercise during MRI is difficult due to space restriction and motion artefacts. To evaluate the feasibility of MRI during stress conditions, dobutamine was used as an alternative to exercise. Haemodynamics, ventricular volumes and wall thickening were measured at rest and during peak dobutamine infusion (15 micrograms.kg-1 x min-1) in 23 normal human subjects. To calculate left ventricular volumes, e... Abstract
Cited 15 times since 1993 (0.5 per year) source: EuropePMC
Magnetic resonance imaging, Volume 11, Issue 2, 1 1 1993, Pages 207-218 Sequential analysis of infarcted and normal myocardium in piglets using in vivo gadolinium-enhanced MR images. van Dijkman PR, Höld KM, van der Laarse A, Holman ER, Ozdemir HI, van der Nat TH, de Roos A, van der Wall EE
Gadolinium-enhanced magnetic resonance (MR) imaging was performed before, and 1 and 3 wk after coronary occlusion in domestic piglets. After administration of the contrast agent gadopentetate dimeglumine, two different enhancement patterns within the infarcted region were observed. The first pattern, showing peripheral enhancement of the infarcted region with absence of contrast in the center, was seen at 1 wk after occlusion at 5 min after administration of the contrast agent. The second patter... Abstract