Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
36 results
Cited 11 times since 2011 (0.8 per year) source: EuropePMC
Current problems in cardiology, Volume 36, Issue 1, 1 1 2011, Pages 9-47 Multimodality imaging in diabetic heart disease. Ng AC, Delgado V, Djaberi R, Schuijf JD, Boogers MJ, Auger D, Bertini M, de Roos A, van der Meer RW, Lamb HJ, Bax JJ
Diabetic heart disease is currently defined as left ventricular dysfunction that occurs independently of coronary artery disease and hypertension. Its underlying etiology is likely to be multifactorial, acting synergistically together to cause myocardial dysfunction. Multimodality cardiac imaging, such as echocardiography, nuclear, computed tomography, and magnetic resonance imaging, can provide invaluable insight into different aspects of the disease process, from imaging at the cellular level... Abstract
Cited 16 times since 2010 (1.2 per year) source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 12, Issue 2, 24 4 2010, Pages 148-155 Subclinical left ventricular dysfunction and coronary atherosclerosis in asymptomatic patients with type 2 diabetes. Scholte AJ, Nucifora G, Delgado V, Djaberi R, Boogers MJ, Schuijf JD, Kharagjitsingh AV, Jukema JW, van der Wall EE, Kroft LJ, de Roos A, Bax JJ
Aims: The aim of the present study was to evaluate whether subclinical left ventricular (LV) systolic dysfunction is independently related to subclinical coronary atherosclerosis in type 2 diabetic patients and if it could provide incremental information over baseline characteristics to identify high-risk patients. Methods and results: A total of 234 asymptomatic, type 2 diabetic patients without overt LV systolic dysfunction underwent coronary artery calcium (CAC) scoring and two-dimensional ec... Abstract
Cited 2 times since 2010 (0.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 97, Issue 1, 11 2 2010, Pages 1-3 Can cardiac [123I]m-iodobenzylguanidine imaging be used for risk stratification of patients with acute myocardial infarction? Boogers MJ, Bax JJ
Cited 25 times since 2010 (1.9 per year) source: EuropePMC
The American journal of cardiology, Volume 106, Issue 12, 4 1 2010, Pages 1675-1679 Impact of clinical presentation and pretest likelihood on the relation between calcium score and computed tomographic coronary angiography. van Werkhoven JM, de Boer SM, Schuijf JD, Cademartiri F, Maffei E, Jukema JW, Boogers MJ, Kroft LJ, de Roos A, Bax JJ
The purpose of the present study was to assess the impact of clinical presentation and pretest likelihood on the relation between coronary calcium score (CCS) and computed tomographic coronary angiography (CTA) to determine the role of CCS as a gatekeeper to CTA in patients presenting with chest pain. In 576 patients with suspected coronary artery disease (CAD), CCS and CTA were performed. CCS was categorized as 0, 1 to 400, and >400. On CT angiogram the presence of significant CAD (≥50% lumi... Abstract
Cited 30 times since 2010 (2.2 per year) source: EuropePMC
European heart journal, Volume 32, Issue 5, 29 5 2010, Pages 637-645 Diagnostic performance of non-invasive multidetector computed tomography coronary angiography to detect coronary artery disease using different endpoints: detection of significant stenosis vs. detection of atherosclerosis. van Velzen JE, Schuijf JD, de Graaf FR, Boersma E, Pundziute G, Spanó F, Boogers MJ, Schalij MJ, Kroft LJ, de Roos A, Jukema JW, van der Wall EE, Bax JJ
Aims: The positive predictive value of multidetector computed tomography angiography (CTA) for detecting significant stenosis remains limited. Possibly CTA may be more accurate in the evaluation of atherosclerosis rather than in the evaluation of stenosis severity. However, a comprehensive assessment of the diagnostic performance of CTA in comparison with both conventional coronary angiography (CCA) and intravascular ultrasound (IVUS) is lacking. Therefore, the aim of the study was to systematic... Abstract
Cited 66 times since 2010 (4.9 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 38, Issue 2, 17 3 2010, Pages 230-238 Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT. Boogers MJ, Chen J, van Bommel RJ, Borleffs CJ, Dibbets-Schneider P, van der Hiel B, Al Younis I, Schalij MJ, van der Wall EE, Garcia EV, Bax JJ
Purpose: The aim of the current study was to evaluate the relationship between the site of latest mechanical activation as assessed with gated myocardial perfusion SPECT (GMPS), left ventricular (LV) lead position and response to cardiac resynchronization therapy (CRT). Methods: The patient population consisted of consecutive patients with advanced heart failure in whom CRT was currently indicated. Before implantation, 2-D echocardiography and GMPS were performed. The echocardiography was perfor... Abstract
Cited 4 times since 2010 (0.3 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 17, Issue 6, 6 1 2010, Pages 1034-1040 Incremental prognostic value of left ventricular function analysis over non-invasive coronary angiography with multidetector computed tomography. de Graaf FR, van Werkhoven JM, van Velzen JE, Antoni ML, Boogers MJ, Kroft LJ, de Roos A, Schalij MJ, Jukema JW, van der Wall EE, Schuijf JD, Bax JJ
Background: The purpose of this study was to determine the prognostic value of computed tomography coronary angiography (CTA)-derived left ventricular (LV) function analysis and to assess its incremental prognostic value over the detection of significant stenosis using CTA. Methods: In 728 patients (400 males, mean age 55 ± 12 years) with known or suspected CAD, the presence of significant stenosis (≥ 50% stenosis) and LV function were assessed using CTA. LV end-systolic volume (LVESV), LV end-d... Abstract
Cited 36 times since 2010 (2.6 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 3, Issue 7, 1 1 2010, Pages 699-709 Automated quantification of stenosis severity on 64-slice CT: a comparison with quantitative coronary angiography. Boogers MJ, Schuijf JD, Kitslaar PH, van Werkhoven JM, de Graaf FR, Boersma E, van Velzen JE, Dijkstra J, Adame IM, Kroft LJ, de Roos A, Schreur JH, Heijenbrok MW, Jukema JW, Reiber JH, Bax JJ
Objectives: This study sought to demonstrate the feasibility of a dedicated algorithm for automated quantification of stenosis severity on multislice computed tomography in comparison with quantitative coronary angiography (QCA). Background: Limited information is available on quantification of coronary stenosis, and previous attempts using semiautomated approaches have been suboptimal. Methods: In patients who had undergone 64-slice computed tomography and invasive coronary angiography, the mos... Abstract
Cited 7 times since 2010 (0.5 per year) source: EuropePMC
Cardiovascular therapeutics, Volume 29, Issue 6, 14 2 2010, Pages e43-53 Coronary artery calcium scoring in cardiovascular risk assessment. Nucifora G, Bax JJ, van Werkhoven JM, Boogers MJ, Schuijf JD
Identification of patients at risk of future coronary artery disease (CAD) events traditionally relies on scoring tools that take demographic and clinical characteristics into account (e.g., the Framingham risk score in the United States and the Heart Score in Europe). Although these scoring tools have been shown to have a good predictive value, they may still fail to recognize a proportion of patients with coronary atherosclerosis at risk for future CAD events. In order to improve risk stratifi... Abstract
Cited 176 times since 2010 (12.7 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 55, Issue 24, 1 1 2010, Pages 2769-2777 Cardiac sympathetic denervation assessed with 123-iodine metaiodobenzylguanidine imaging predicts ventricular arrhythmias in implantable cardioverter-defibrillator patients. Boogers MJ, Borleffs CJ, Henneman MM, van Bommel RJ, van Ramshorst J, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Schalij MJ, Bax JJ
Objectives: The purpose of this study was to evaluate whether 123-iodine metaiodobenzylguanidine (123-I MIBG) imaging predicts ventricular arrhythmias causing appropriate implantable cardioverter-defibrillator (ICD) therapy (primary end point) and the composite of appropriate ICD therapy or cardiac death (secondary end point). Background: Although cardiac sympathetic denervation is associated with ventricular arrhythmias, limited data are available on the predictive value of sympathetic nerve im... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 17, Issue 3, 1 1 2010, Pages 354-358 Should mechanical dyssynchrony be assessed in patients with implantable cardioverter-defibrillators? Boogers MJ, Schalij MJ, Bax JJ
Cited 51 times since 2010 (3.7 per year) source: EuropePMC
Investigative radiology, Volume 45, Issue 6, 1 1 2010, Pages 331-340 Diagnostic accuracy of 320-row multidetector computed tomography coronary angiography to noninvasively assess in-stent restenosis. de Graaf FR, Schuijf JD, van Velzen JE, Boogers MJ, Kroft LJ, de Roos A, Reiber JH, Sieders A, Spanó F, Jukema JW, Schalij MJ, van der Wall EE, Bax JJ
Objectives: Percutaneous coronary intervention with stent implantation is routinely performed to treat patients with obstructive coronary artery disease. However, thus far, noninvasive assessment of in-stent restenosis has been challenging. Recently, 320-row multidetector computed tomography coronary angiography (CTA) was introduced, allowing volumetric image acquisition of the heart in a single heart beat or gantry rotation. The aim of this study was to evaluate the diagnostic performance of 32... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 6 Suppl G, 1 1 2010, Pages G57-64 Quantification of stenosis severity on multidetector row computed tomography. Boogers MJ, Schuijf JD
A comprehensive evaluation of coronary anatomy and atherosclerosis can be provided by MDCT. Currently, several studies have used either manual or semi-automated algorithms for quantification of different plaque characteristics, in particular the degree of luminal narrowing. Although the feasibility of these quantitative algorithms has been demonstrated, further refinement of quantitative CT algorithms is currently indicated to allow a comprehensive yet fully automated analysis of plaque characte... Abstract
Cited 26 times since 2010 (1.8 per year) source: EuropePMC
Current cardiology reports, Volume 12, Issue 2, 1 1 2010, Pages 185-191 The use of nuclear imaging for cardiac resynchronization therapy. Chen J, Boogers MJ, Bax JJ, Soman P, Garcia EV
Cardiac resynchronization therapy (CRT) has shown benefits in patients with end-stage heart failure, depressed left ventricular (LV) ejection fraction (< or = 35%), and prolonged QRS duration (> or = 120 ms). However, based on the conventional criteria, 20% to 40% of patients fail to respond to CRT. Studies have focused on important parameters for predicting CRT response, such as LV dyssynchrony, scar burden, LV lead position, and site of latest activation. Phase analysis allows nuclear ca... Abstract
Cited 16 times since 2008 (1 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 10 Suppl 3, 1 1 2008, Pages iii101-5 Is nuclear imaging a viable alternative technique to assess dyssynchrony? Chen J, Bax JJ, Henneman MM, Boogers MJ, Garcia EV
Cardiac resynchronization therapy (CRT) has shown benefits in patients with end-stage heart failure (HF) (NYHA class III or IV), depressed left ventricular (LV) ejection fraction, and prolonged QRS duration (>120 ms). However, at least 30% of the patients who meet the above criteria show no response to CRT. It has shown with echocardiography that the presence of LV mechanical dyssynchrony is an important predictor for response to CRT. However, echocardiography requires expertise to produce re... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
Minerva cardioangiologica, Volume 56, Issue 2, 1 1 2008, Pages 227-235 Measuring left ventricular mechanical dyssynchrony from ECG-gated SPECT myocardial perfusion imaging. Chen J, Garcia EV, Henneman MM, Bax JJ, Boogers MJ, Trimble MA, Borges-Neto S, Velazquez EJ, Iskandrian AE
Cardiac resynchronization therapy (CRT) has shown benefits in patients with severe heart failure. The traditional criteria to select patients for CRT (New York Heart Association [NYHA] class III or IV, depressed left ventricular [LV] ejection fraction, and prolonged QRS duration) result in at least 30% of the selected patients with no response to CRT. Recent studies with echocardiography have shown that the presence of LV dyssynchrony is an important predictor for response to CRT. However, the r... Abstract