Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
50 results
Cited 13 times since 2015 (1.5 per year) source: EuropePMC
European journal of heart failure, Volume 17, Issue 10, 4 1 2015, Pages 1042-1049 Anaemia in patients with aortic stenosis: influence on long-term prognosis. Ng AC, Kong WK, Kamperidis V, Bertini M, Antoni ML, Leung DY, Marsan NA, Delgado V, Bax JJ
Aims: The prognostic implications of anaemia in patients with aortic stenosis (AS) remain unclear. Accordingly, the present study aimed to evaluate the prognostic implications of anaemia in AS patients before and after aortic valve replacement (AVR). Methods and results: A total of 856 AS patients (age 71 ± 12 years, 60.2% male, 47.4% severe AS) were included. The mean haemoglobin (Hb) level was 13.2 ± 1.8 g/dL, and the prevalence of anaemia (Hb Abstract
Cited 12 times since 2014 (1.2 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 27, Issue 3, 13 2 2014, Pages 239-248 Association between multilayer left ventricular rotational mechanics and the development of left ventricular remodeling after acute myocardial infarction. Abate E, Hoogslag GE, Leong DP, Bertini M, Antoni ML, Nucifora G, Joyce E, Holman ER, Siebelink HM, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Background: The identification of patients at risk for developing left ventricular (LV) remodeling after acute myocardial infarction (AMI) has crucial prognostic implications. The aims of this study were (1) to investigate the relationship between peak subepicardial and subendocardial twist and infarct transmurality, as assessed using contrast-enhanced magnetic resonance imaging, and (2) to evaluate the association between peak subepicardial and subendocardial twist and LV remodeling 6 months af... Abstract
Cited 5 times since 2013 (0.5 per year) source: EuropePMC
Heart and vessels, Volume 29, Issue 5, 27 4 2013, Pages 619-628 Prognostic implications of left ventricular regional function heterogeneity assessed with two-dimensional speckle tracking in patients with ST-segment elevation myocardial infarction and depressed left ventricular ejection fraction. Hoogslag GE, Thijssen J, Höke U, Boden H, Antoni ML, Debonnaire P, Haeck ML, Holman ER, Bax JJ, Ajmone Marsan N, Schalij MJ, Delgado V
The aim of the current study was to evaluate the prognostic implications of myocardial tissue heterogeneity assessed with two-dimensional speckle-tracking echocardiography in patients three months after first ST-segment elevation myocardial infarction (STEMI) with left ventricular ejection fraction (LVEF) ≤35 %. For this purpose, a total of 79 patients with first STEMI and LVEF ≤35 % at three months postinfarction were evaluated. Based on left ventricular (LV) speckle-tracking longitudinal strai... Abstract
Cited 37 times since 2012 (3.1 per year) source: EuropePMC
The American journal of cardiology, Volume 110, Issue 7, 19 3 2012, Pages 961-967 Value of three-dimensional speckle-tracking longitudinal strain for predicting improvement of left ventricular function after acute myocardial infarction. Abate E, Hoogslag GE, Antoni ML, Nucifora G, Delgado V, Holman ER, Schalij MJ, Bax JJ, Marsan NA
Identification of patients with reversible left ventricular (LV) dysfunction has important prognostic implications after acute myocardial infarction (AMI). This study aimed to determine the value of LV segmental and global longitudinal strains assessed with 3-dimensional (3D) speckle-tracking analysis in predicting improvement of LV function after AMI. One hundred fifty-three patients (80% men, 59 ± 11 years old) with AMI and treated with primary percutaneous coronary intervention underwent 3D e... Abstract
Cited 14 times since 2012 (1.2 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 25, Issue 6, 17 3 2012, Pages 674-681 Right ventricular longitudinal peak systolic strain measurements from the subcostal view in patients with suspected pulmonary hypertension: a feasibility study. Haeck ML, Scherptong RW, Antoni ML, Marsan NA, Vliegen HW, Holman ER, Schalij MJ, Bax JJ, Delgado V
Background: The assessment of right ventricular (RV) function with two-dimensional echocardiography can be challenging in patients with pulmonary hypertension, especially in those with chronic pulmonary disease. The aim of the present study was to evaluate the feasibility of measuring RV longitudinal peak systolic strain (LPSS) in the echocardiographic subcostal view in patients with suspected pulmonary hypertension. Methods: A total of 179 patients evaluated for pulmonary hypertension were incl... Abstract
Cited 81 times since 2012 (6.7 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 5, Issue 3, 12 2 2012, Pages 383-391 Global longitudinal strain predicts long-term survival in patients with chronic ischemic cardiomyopathy. Bertini M, Ng AC, Antoni ML, Nucifora G, Ewe SH, Auger D, Marsan NA, Schalij MJ, Bax JJ, Delgado V
Background: Left ventricular (LV) global longitudinal strain (GLS) is a measure of the active shortening of the LV in the longitudinal direction, which can be assessed with speckle-tracking echocardiography. The aims of this evaluation were to validate the prognostic value of GLS as a new index of LV systolic function in a large cohort of patients with chronic ischemic cardiomyopathy and to determine the incremental value of GLS to predict long-term outcome over other strong and well-established... Abstract
Cited 16 times since 2012 (1.3 per year) source: EuropePMC
The American journal of cardiology, Volume 109, Issue 2, 1 1 2012, Pages 187-194 Cardiovascular mortality and heart failure risk score for patients after ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention (Data from the Leiden MISSION! Infarct Registry). Antoni ML, Hoogslag GE, Boden H, Liem SS, Boersma E, Fox K, Schalij MJ, Bax JJ, Delgado V
The risk scores developed for the prediction of an adverse outcome in patients after ST-segment elevation myocardial infarction (STEMI) have mostly addressed patients treated with thrombolysis and evaluated solely all-cause mortality as the primary end point. Primary percutaneous coronary intervention in patients with STEMI has improved the outcome significantly and might have changed the relative contribution of different risk factors. Our patient population included 1,484 consecutive patients... Abstract
Cited 11 times since 2011 (0.9 per year) source: EuropePMC
Coronary artery disease, Volume 22, Issue 8, 1 1 2011, Pages 533-536 Distribution of culprit lesions in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention. Antoni ML, Yiu KH, Atary JZ, Delgado V, Holman ER, van der Wall EE, Schuijf JD, Bax JJ, Schalij MJ
Objectives: Data regarding the distribution of vulnerable lesions in the coronary arteries are scarce. The aim was to evaluate the frequency and distribution of culprit lesions in patients with ST-segment elevation acute myocardial infarction. In addition, the location of culprit lesions was related to infarct size. Methods: Consecutive patients (N=1533, mean age 61±12 years) were evaluated. All patients were treated with primary percutaneous coronary intervention and underwent two-dimensional e... Abstract
Cited 14 times since 2011 (1.1 per year) source: EuropePMC
The American journal of cardiology, Volume 108, Issue 12, 8 2 2011, Pages 1689-1696 Prevalence of dyssynchrony and relation with long-term outcome in patients after acute myocardial infarction. Antoni ML, Boden H, Hoogslag GE, Ewe SH, Auger D, Holman ER, van der Wall EE, Schalij MJ, Bax JJ, Delgado V
The impact of left ventricular (LV) dyssynchrony on the long-term outcomes of patients with acute myocardial infarction (AMI) remains unknown. The purpose of the present study was to evaluate the prevalence of LV dyssynchrony after AMI and the potential relation with adverse events. A total of 976 consecutive patients admitted with AMI treated with primary percutaneous coronary intervention were evaluated. Two-dimensional echocardiography was performed Abstract
Cited 13 times since 2011 (1 per year) source: EuropePMC
European journal of heart failure, Volume 13, Issue 10, 25 4 2011, Pages 1133-1139 The effect of cardiac resynchronization therapy on left ventricular diastolic function assessed with speckle-tracking echocardiography. Shanks M, Antoni ML, Hoke U, Bertini M, Ng AC, Auger D, Marsan NA, van Erven L, Holman ER, Schalij MJ, Bax JJ, Delgado V
Aims: Changes in left ventricular (LV) diastolic function after cardiac resynchronization therapy (CRT) in relation to LV reverse remodelling and heart failure aetiology have not been extensively characterized. The aims of the study were to evaluate changes in LV diastolic function with speckle-tracking echocardiography in relation to: (i) cardiac resynchronization therapy response (LV remodelling) and (ii) heart failure aetiology. Methods and results: A total of 192 heart failure patients under... Abstract
Cited 44 times since 2011 (3.5 per year) source: EuropePMC
European heart journal, Volume 33, Issue 1, 22 4 2011, Pages 96-102 Relationship between discharge heart rate and mortality in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Antoni ML, Boden H, Delgado V, Boersma E, Fox K, Schalij MJ, Bax JJ
Aims: In patients with coronary artery disease, the prognostic value of heart rate has been mainly evaluated in patients with left ventricular dysfunction. Patients with ST-segment elevation acute myocardial infarction (STEMI) are currently treated with primary percutaneous coronary intervention (PCI) and in this contemporary population of patients, the relationship between heart rate and mortality during a follow-up >1 year has not been investigated. Methods and results: The population compr... Abstract
Cited 24 times since 2011 (1.9 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 24, Issue 10, 6 1 2011, Pages 1126-1133 Comprehensive assessment of changes in left atrial volumes and function after ST-segment elevation acute myocardial infarction: role of two-dimensional speckle-tracking strain imaging. Antoni ML, Ten Brinke EA, Marsan NA, Atary JZ, Holman ER, van der Wall EE, Schalij MJ, Bax JJ, Delgado V
Background: Left atrial (LA) size has been associated with adverse outcome in patients after acute myocardial infarction. However, data about the occurrence of late LA enlargement and changes in LA function during follow-up are scarce. The purpose of the current study was to evaluate changes in LA size and function during 1-year follow-up. Methods: The study population comprised 407 patients with acute myocardial infarction who were treated with primary percutaneous coronary intervention. At bas... Abstract
Cited 43 times since 2011 (3.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 97, Issue 16, 25 4 2011, Pages 1332-1337 Left atrial strain is related to adverse events in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Antoni ML, ten Brinke EA, Atary JZ, Marsan NA, Holman ER, Schalij MJ, Bax JJ, Delgado V
Background: Left atrial (LA) maximal volume is of prognostic value in patients after acute myocardial infarction (AMI). Recently, LA mechanical function and LA strain have been introduced as alternative methods to assess LA performance more accurately. Objective: To evaluate the relation between LA volume, mechanical function and strain, and adverse events in patients after AMI. Methods: Patients with AMI underwent two-dimensional echocardiography within 48 h of admission. LA volume and LA perfo... Abstract
Cited 104 times since 2011 (8 per year) source: EuropePMC
European heart journal, Volume 32, Issue 12, 29 5 2011, Pages 1542-1550 Alterations in multidirectional myocardial functions in patients with aortic stenosis and preserved ejection fraction: a two-dimensional speckle tracking analysis. Ng AC, Delgado V, Bertini M, Antoni ML, van Bommel RJ, van Rijnsoever EP, van der Kley F, Ewe SH, Witkowski T, Auger D, Nucifora G, Schuijf JD, Poldermans D, Leung DY, Schalij MJ, Bax JJ
Aims: To identify changes in multidirectional strain and strain rate (SR) in patients with aortic stenosis (AS). Methods and results: A total of 420 patients (age 66.1 ± 14.5 years, 60.7% men) with aortic sclerosis, mild, moderate, and severe AS with preserved left ventricular (LV) ejection fraction [(EF), ≥50%] were included. Multidirectional strain and SR imaging were performed by two-dimensional speckle tracking. Patients were more likely to be older (P < 0.001) and at a worse New York Hea... Abstract
Cited 70 times since 2011 (5.3 per year) source: Scopus
The Annals of thoracic surgery, Volume 92, Issue 4, 21 3 2011, Pages 1244-1251 Outcomes after transcatheter aortic valve implantation: transfemoral versus transapical approach. Ewe SH, Delgado V, Ng AC, Antoni ML, van der Kley F, Marsan NA, de Weger A, Tavilla G, Holman ER, Schalij MJ, Bax JJ
Background: Transcatheter aortic valve implantation is commonly implanted through a transfemoral (TFA) or transapical approach (TAA) for patients with severe aortic stenosis. This study aimed to describe the clinical and echocardiographic outcomes of TFA versus TAA. Methods: Clinical and echocardiographic evaluations were performed at baseline, post-TAVI (transcatheter aortic valve implantation), at 6 and 12 months follow-up in 107 consecutive patients who underwent TAVI with balloon-expandable... Abstract
Cited 12 times since 2011 (0.9 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 4, Issue 2, 5 1 2011, Pages 122-129 Intramyocardial bone marrow-derived mononuclear cell injection for chronic myocardial ischemia: the effect on diastolic function. van Ramshorst J, Antoni ML, Beeres SL, Roes SD, Delgado V, Rodrigo SF, de Roos A, Holman ER, Fibbe WE, Lamb HJ, Zwaginga JJ, Boersma E, van der Wall EE, Schalij MJ, Atsma DE, Bax JJ
Background: The present substudy of a recently published randomized trial aimed to investigate the effect of intramyocardial bone marrow cell injection on diastolic function in patients with chronic myocardial ischemia. Methods and results: In a total of 50 patients, diastolic function was evaluated before and 3 months after bone marrow cell injection using standard echocardiography and strain analysis. In addition, MRI-derived transmitral flow measurements were obtained in a subset of 36 patien... Abstract
Cited 29 times since 2010 (2.2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 21, 1 1 2010, Pages 1737-1743 Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers. Bertini M, Delgado V, Nucifora G, Ajmone Marsan N, Ng AC, Shanks M, Antoni ML, van de Veire NR, van Bommel RJ, Rapezzi C, Schalij MJ, Bax JJ
Objective: Subendocardial and subepicardial layers have opposite orientation of the myofibres and they are differently affected by coronary artery disease. This study investigated the differences in subendocardial and subepicardial left ventricular (LV) twist in patients with coronary artery disease. Methods: 214 patients were included in the study: 60 with first ST elevation myocardial infarction (STEMI), 111 with chronic ischaemic heart failure (HF) and 43 normal subjects. Real-time three-dime... Abstract
Cited 25 times since 2010 (1.8 per year) source: EuropePMC
European journal of heart failure, Volume 12, Issue 10, 1 1 2010, Pages 1101-1110 Prediction of atrial fibrillation in patients with an implantable cardioverter-defibrillator and heart failure. Bertini M, Borleffs CJ, Delgado V, Ng AC, Piers SR, Shanks M, Antoni ML, Biffi M, Boriani G, Schalij MJ, Bax JJ, Van de Veire NR
Aims: Heart failure and atrial fibrillation (AF) frequently coexist and AF worsens heart failure prognosis. Device-based diagnostics derived from implantable cardioverter-defibrillator (ICD) interrogation provide an accurate method for detecting AF episodes. This study sought to determine clinical and echocardiographic predictors of AF occurrence, including an index of total atrial conduction time derived by tissue Doppler imaging (PA-TDI duration), in patients with heart failure. Moreover, the... Abstract
Cited 10 times since 2010 (0.7 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 18, Issue 9, 1 1 2010, Pages 408-415 Standardised pre-hospital care of acute myocardial infarction patients: MISSION! guidelines applied in practice. Atary JZ, de Visser M, van den Dijk R, Bosch J, Liem SS, Antoni ML, Bootsma M, Viergever EP, Kirchhof CJ, Padmos I, Sedney MI, van Exel HJ, Verwey HF, Atsma DE, van der Wal EE, Jukema JW, Schalij MJ
Background. To improve acute myocardial infarction (AMI) care in the region 'Hollands-Midden' (the Netherlands), a standardised guideline-based care program was developed (MISSION!). This study aimed to evaluate the outcome of the pre-hospital part of the MISSION! program and to study potential differences in pre-hospital care between four areas of residency.Methods. Time-to-treatment delays, AMI risk profile, cardiac enzymes, hospital stay, in-hospital mortality, and pre-AMI medicatio... Abstract
Cited 4 times since 2010 (0.3 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 17, Issue 6, 6 1 2010, Pages 1034-1040 Incremental prognostic value of left ventricular function analysis over non-invasive coronary angiography with multidetector computed tomography. de Graaf FR, van Werkhoven JM, van Velzen JE, Antoni ML, Boogers MJ, Kroft LJ, de Roos A, Schalij MJ, Jukema JW, van der Wall EE, Schuijf JD, Bax JJ
Background: The purpose of this study was to determine the prognostic value of computed tomography coronary angiography (CTA)-derived left ventricular (LV) function analysis and to assess its incremental prognostic value over the detection of significant stenosis using CTA. Methods: In 728 patients (400 males, mean age 55 ± 12 years) with known or suspected CAD, the presence of significant stenosis (≥ 50% stenosis) and LV function were assessed using CTA. LV end-systolic volume (LVESV), LV end-d... Abstract