Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7487 results
Cited 3 times since 2012 (0.2 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 42, Issue 1, 26 4 2012, Pages 50-55 Effect of age on exercise capacity and cardiac reserve in patients with pulmonary atresia with intact ventricular septum after biventricular repair. Romeih S, Groenink M, van der Plas MN, Spijkerboer AM, Hazekamp MG, Luijnenburg S, Mulder BJ, Blom NA
Objectives: In patients with pulmonary atresia with intact ventricular septum (PAIVS), biventricular repair is considered to be the optimal treatment option in the absence of significant right ventricular (RV) hypoplasia. However, long-term clinical outcome studies are limited. We evaluated exercise capacity and cardiac function during pharmacological stress in children and young adults with PAIVS after biventricular repair. Methods: Ten PAIVS patients after biventricular repair, with a median a... Abstract
Cited 48 times since 2012 (3.9 per year) source: EuropePMC
The European respiratory journal, Volume 40, Issue 2, 26 4 2012, Pages 306-312 Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor. Stolk J, Stockley RA, Stoel BC, Cooper BG, Piitulainen E, Seersholm N, Chapman KR, Burdon JG, Decramer M, Abboud RT, Mannes GP, Wouters EF, Garrett JE, Barros-Tizon JC, Russi EW, Lomas DA, MacNee WA, Rames A
Palovarotene is an oral γ-selective retinoid agonist. In animal emphysema models, palovarotene reduced inflammation, promoted structural repair and functional improvement. REPAIR (Retinoid treatment of Emphysema in Patients on the α(1)-antitrypsin International Registry), was an investigator-initiated, double-blind, placebo-controlled randomised study to assess the safety and efficacy of 5 mg·day(-1) palovarotene given for 1 year to 262 patients with severe α(1)-antitrypsin deficiency and emphys... Abstract
Cited 105 times since 2012 (8.6 per year) source: EuropePMC
European heart journal, Volume 33, Issue 8, 26 4 2012, Pages 1007-1016 Automated quantification of coronary plaque with computed tomography: comparison with intravascular ultrasound using a dedicated registration algorithm for fusion-based quantification. Boogers MJ, Broersen A, van Velzen JE, de Graaf FR, El-Naggar HM, Kitslaar PH, Dijkstra J, Delgado V, Boersma E, de Roos A, Schuijf JD, Schalij MJ, Reiber JH, Bax JJ, Jukema JW
Aims: Previous studies have used semi-automated approaches for coronary plaque quantification on multi-detector row computed tomography (CT), while an automated quantitative approach using a dedicated registration algorithm is currently lacking. Accordingly, the study aimed to demonstrate the feasibility and accuracy of automated coronary plaque quantification on cardiac CT using dedicated software with a novel 3D coregistration algorithm of CT and intravascular ultrasound (IVUS) data sets. Meth... Abstract
Cited 6 times since 2012 (0.5 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 28, Issue 8, 24 4 2012, Pages 2065-2071 Non-invasive assessment of atherosclerotic coronary lesion length using multidetector computed tomography angiography: comparison to quantitative coronary angiography. van Velzen JE, de Graaf MA, Ciarka A, de Graaf FR, Schalij MJ, Kroft LJ, de Roos A, Jukema JW, Reiber JH, Schuijf JD, Bax JJ, van der Wall EE
Multidetector computed tomography angiography (CTA) provides information on plaque extent and stenosis in the coronary wall. More accurate lesion assessment may be feasible with CTA as compared to invasive coronary angiography (ICA). Accordingly, lesion length assessment was compared between ICA and CTA in patients referred for CTA who underwent subsequent percutaneous coronary intervention (PCI). 89 patients clinically referred for CTA were subsequently referred for ICA and PCI. On CTA, lesion... Abstract
Cited 24 times since 2012 (2 per year) source: EuropePMC
European heart journal, Volume 33, Issue 7, 24 4 2012, Pages 913-920 Effect of cardiac resynchronization therapy in patients without left intraventricular dyssynchrony. Auger D, Bleeker GB, Bertini M, Ewe SH, van Bommel RJ, Witkowski TG, Ng AC, van Erven L, Schalij MJ, Bax JJ, Delgado V
Aims: To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical dyssynchrony. Methods and results: A total of 290 heart failure patients (age 67 ± 10 years, 77% males) without significant baseline LV dyssynchrony ( Abstract
Cited 16 times since 2012 (1.3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 93, Issue 3, 23 4 2012, Pages 849-855 Long-term results of reoperation for left atrioventricular valve regurgitation after correction of atrioventricular septal defects. Hoohenkerk GJ, Bruggemans EF, Koolbergen DR, Rijlaarsdam ME, Hazekamp MG
Background: Long-term results of reoperation for left atrioventricular valve regurgitation (LAVVR) after previous correction of atrioventricular septal defect (AVSD) are scarce. We evaluated long-term outcome of reoperation for LAVVR and identified risk factors for reoperation. Methods: Between December 1976 and July 2006, 45 of 312 patients with correction of different AVSDs underwent reoperation for LAVVR. The cohort of 267 patients who did not need reoperation for LAVVR allowed for the identi... Abstract
Cited 10 times since 2012 (0.8 per year) source: EuropePMC
European heart journal, Volume 33, Issue 15, 22 4 2012, Pages 1934-1941 Predictors of long-term benefit of cardiac resynchronization therapy in patients with right bundle branch block. Leong DP, Höke U, Delgado V, Auger D, Thijssen J, van Erven L, Bax JJ, Schalij MJ, Marsan NA
Aims: The aims of this study were: (i) to characterize consecutive cardiac resynchronization therapy (CRT) recipients with right bundle branch block (RBBB) in comparison with left bundle branch block (LBBB) and (ii) to identify independent predictors of long-term outcome among CRT recipients with RBBB. The presence of RBBB has been associated with poorer prognosis after CRT compared with LBBB; however, little is known about the differences in cardiac mechanics between RBBB and LBBB patients. Fur... Abstract
Cited 8 times since 2012 (0.7 per year) source: EuropePMC
Journal of electrocardiology, Volume 45, Issue 3, 20 3 2012, Pages 312-318 Diagnosis and mortality prediction in pulmonary hypertension: the value of the electrocardiogram-derived ventricular gradient. Scherptong RW, Henkens IR, Kapel GF, Swenne CA, van Kralingen KW, Huisman MV, Schuerwegh AJ, Bax JJ, van der Wall EE, Schalij MJ, Vliegen HW
Purpose: The aim of this study was to investigate the use of the electrocardiogram-derived ventricular gradient, projected on the x-axis (VGx), for detection of pulmonary hypertension (PH) and for prediction of all-cause mortality in PH patients. Methods: In patients referred for PH screening (n = 216), the VGx was calculated semiautomatically from the electrocardiogram and was defined as abnormal when less than 24 mV · ms. The VGx of PH patients was compared with the VGx of patients without PH.... Abstract
Cited 158 times since 2012 (12.9 per year) source: EuropePMC
Cardiovascular research, Volume 94, Issue 2, 20 3 2012, Pages 276-283 The innate immune response in reperfused myocardium. Timmers L, Pasterkamp G, de Hoog VC, Arslan F, Appelman Y, de Kleijn DP
One of the major therapeutic challenges in the arena of interventional cardiology is to design strategies aimed at reducing myocardial tissue damage after myocardial infarction. In response to tissue injury, an innate immune response is initiated that orchestrates homeostatic responses and is a prerequisite for subsequent wound healing. An exaggerated inflammatory reaction, however, countervenes these beneficial effects and contributes to maladaptive tissue damage. Herein, we discuss the pathway... Abstract
Cited 4 times since 2012 (0.3 per year) source: EuropePMC
Acta anaesthesiologica Scandinavica, Volume 56, Issue 4, 19 3 2012, Pages 449-458 Xenon is not superior to isoflurane on cardiovascular function during experimental acute pulmonary hypertension. Roehl AB, Steendijk P, Rossaint R, Bleilevens C, Goetzenich A, Hein M
Background: Acute right ventricular afterload increase is a known perioperative challenge for the anaesthetic regime especially for patients with a compromised right ventricle. The accused negative inotropic action of volatile anaesthetics, with the exception of xenon, might be crucial for the adaptation of the right ventricle. Methods: Reversible pulmonary hypertension (mean pressure 40 mmHg) was induced by an infusion of the stable thromboxane A(2) analog U46619 in a porcine model (n = 35). Th... Abstract
Pacing and clinical electrophysiology : PACE, Volume 35, Issue 7, 16 3 2012, Pages 884-886 Single and inappropriate shock delivered out of tachycardia: device dysfunction? Fontenla A, Carrero D, Salguero R, López-Gil M, De Riva M, Arribas F
Cited 63 times since 2012 (5.1 per year) source: EuropePMC
European journal of clinical nutrition, Volume 66, Issue 3, 11 2 2012, Pages 399-404 Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT. van der Meij BS, Langius JA, Spreeuwenberg MD, Slootmaker SM, Paul MA, Smit EF, van Leeuwen PA
Background/objectives: Our objective was to investigate effects of an oral nutritional supplement containing n-3 polyunsaturated fatty acids (FAs) on quality of life, performance status, handgrip strength and physical activity in patients with non-small cell lung cancer (NSCLC) undergoing multimodality treatment. Subjects/methods: In a double-blind experiment, 40 patients with stage III NSCLC were randomised to receive 2 cans/day of a protein- and energy-dense oral nutritional supplement contain... Abstract
The Journal of thoracic and cardiovascular surgery, Volume 144, Issue 2, 11 2 2012, Pages 506-508 Surgical treatment of residual systolic anterior motion after otherwise successful percutaneous transluminal septal myocardial ablation: a case report. Hjortnaes J, Leemans PA, ten Cate FJ, van Herwerden LA
Cited 98 times since 2012 (8 per year) source: EuropePMC
The Journal of clinical endocrinology and metabolism, Volume 97, Issue 3, 11 2 2012, Pages 852-861 Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Nanchen D, Gussekloo J, Westendorp RG, Stott DJ, Jukema JW, Trompet S, Ford I, Welsh P, Sattar N, Macfarlane PW, Mooijaart SP, Rodondi N, de Craen AJ, PROSPER Group
Context: Subclinical thyroid dysfunction is common in older people. However, its clinical importance is uncertain. Objective: Our objective was to determine the extent to which subclinical hyperthyroidism and hypothyroidism influence the risk of heart failure and cardiovascular diseases in older people. Setting and design: The Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) is an prospective cohort study. Patients: Patients included men and women aged 70-82 yr (n=5316) with kno... Abstract
Cited 31 times since 2012 (2.5 per year) source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Volume 14, 9 2 2012, Pages 2 Bramwell-Hill modeling for local aortic pulse wave velocity estimation: a validation study with velocity-encoded cardiovascular magnetic resonance and invasive pressure assessment. Westenberg JJ, van Poelgeest EP, Steendijk P, Grotenhuis HB, Jukema JW, de Roos A
Background: The Bramwell-Hill model describes the relation between vascular wall stiffness expressed in aortic distensibility and the pulse wave velocity (PWV), which is the propagation speed of the systolic pressure wave through the aorta. The main objective of this study was to test the validity of this model locally in the aorta by using PWV-assessments based on in-plane velocity-encoded cardiovascular magnetic resonance (CMR), with invasive pressure measurements serving as the gold standard.... Abstract
Cited 19 times since 2012 (1.5 per year) source: EuropePMC
Lung cancer (Amsterdam, Netherlands), Volume 76, Issue 3, 9 2 2012, Pages 452-456 History of tuberculosis as an independent prognostic factor for lung cancer survival. Heuvers ME, Aerts JG, Hegmans JP, Veltman JD, Uitterlinden AG, Ruiter R, Rodenburg EM, Hofman A, Bakker M, Hoogsteden HC, Stricker BH, van Klaveren RJ
Introduction: It is well known that pulmonary tuberculosis is associated with an increased risk of lung cancer. We investigated whether a history of pulmonary tuberculosis is an independent risk factor for lung cancer survival in Caucasian patients. Methods: The data of the prospective population-based cohort of The Rotterdam Study were used. During a mean follow-up time of 18 years, there were 214 incident cases of pathology-proven lung cancer in a source population of 7983 study participants.... Abstract
European heart journal. Cardiovascular Imaging, Volume 13, Issue 6, 9 2 2012, Pages 535 Isolated posterior mitral leaflet cleft resembling trileaflet valve. Vignalou JB, Ewe SH, Schalij MJ, Bax JJ, Delgado V
Cited 16 times since 2012 (1.3 per year) source: EuropePMC
The American journal of cardiology, Volume 109, Issue 2, 1 1 2012, Pages 187-194 Cardiovascular mortality and heart failure risk score for patients after ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention (Data from the Leiden MISSION! Infarct Registry). Antoni ML, Hoogslag GE, Boden H, Liem SS, Boersma E, Fox K, Schalij MJ, Bax JJ, Delgado V
The risk scores developed for the prediction of an adverse outcome in patients after ST-segment elevation myocardial infarction (STEMI) have mostly addressed patients treated with thrombolysis and evaluated solely all-cause mortality as the primary end point. Primary percutaneous coronary intervention in patients with STEMI has improved the outcome significantly and might have changed the relative contribution of different risk factors. Our patient population included 1,484 consecutive patients... Abstract
Nederlands tijdschrift voor geneeskunde, Volume 156, Issue 41, 1 1 2012, Pages A3604 [Surgery in patients with centrally-situated non-small cell lung carcinoma: lung-parenchymal sparing procedure versus pneumonectomy]. Versteegh M, Smeenk HG, Annema J, Wijers O, Tjon A, Wolterbeek R, van Kralingen K, Klautz R, Braun J
Objective: To examine if lung-parenchymal sparing resection ('sleeve' resection) is a safe and oncologically responsible alternative to pneumonectomy in patients with central tumours. Further, to evaluate in how far this technique is being used in the Netherlands. Design: Retrospective cohort study. Method: Patients undergoing either lung-parenchymal sparing procedure or pneumonectomy for centrally situated non-small cell lung carcinoma (NSCLC) between January 1995 and January 2010 wer... Abstract
Cited 6 times since 2012 (0.5 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 41, Issue 1, 1 1 2012, Pages 74-80; discussion 80-1 Management of mitral regurgitation during left ventricular reconstruction for ischemic heart failure. Klein P, Braun J, Holman ER, Versteegh MI, Verwey HF, Dion RA, Bax JJ, Klautz RJ
Objective: Remodeling of the left ventricle (LV) in ischemic cardiomyopathy frequently leads to functional mitral regurgitation (MR). The indication for correcting MR in patients undergoing LV reconstruction (LVR) is unclear. In this study, we evaluated our strategy of correcting MR≥grade 2+ by restrictive mitral annuloplasty (RMA) during LVR. Methods: We studied 92 consecutive patients (76 men, mean age 61±10 years) who underwent LVR for ischemic heart failure (IHF). RMA was performed in all pa... Abstract